The search for potent, small molecule NNRTIs: A review

Bioorganic and Medicinal Chemistry

Volumn 17, Issue 16, 2009, Pages 5744-5762

  Prajapati, Dhaval G ^a   Ramajayam, R ^b   Yadav, Mange Ram ^a   Giridhar, Rajani ^a  

^a Faculty of Technology and Engineering   (India)

^b INDIAN INSTITUTE OF TECHNOLOGY MADRAS   (India)

Author keywords

AIDS, Acquired immunodeficiency Syndrome; NNRTIs, non nucleoside reverse transcriptase inhibitors; RT, Reverse transcriptase

Indexed keywords

3 [(4,7 DICHLORO 2 BENZOXAZOLYLMETHYL)AMINO] 5 ETHYL 6 METHYL 2(1H) PYRIDONE; 4,5,6,7 TETRAHYDRO 5 METHYLIMIDAZOL[4,5,1 JK][1,4]BENZODIAZEPIN 2(1H) ONE DERIVATIVE; ABACAVIR; ACETANILIDE DERIVATIVE; ANILIDE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; BENZOPHENONE DERIVATIVE; BENZOXAZINONE DERIVATIVE; DAPIVIRINE; DELAVIRDINE; DIDANOSINE; EFAVIRENZ; EMIVIRINE; EMTRICITABINE; ETRAVIRINE; LAMIVUDINE; LOVIRIDE; MEN 10979; N [4 CHLORO 3 (3 METHYL 2 BUTENYLOXY)PHENYL] 2 METHYL 3 FURANCARBOTHIOAMIDE; NEVIRAPINE; NSC 287474; NSC 625487; PYRIDONE DERIVATIVE; PYRIMIDINE DERIVATIVE; QUINAZOLINONE DERIVATIVE; R 1545508; R 157208; R 165481; R 221239; RD 42024; RILPIVIRINE; RNA DIRECTED DNA POLYMERASE; RNA DIRECTED DNA POLYMERASE INHIBITOR; STAVUDINE; TALVIRALINE; TENOFOVIR DISOPROXIL; TIVIRAPINE; TRIAZINE DERIVATIVE; TROVIRDINE; U 31355; UK 129485; UNCLASSIFIED DRUG; UNINDEXED DRUG; ZALCITABINE;

ACQUIRED IMMUNE DEFICIENCY SYNDROME; CYTOTOXICITY; DRUG BINDING; DRUG SYNTHESIS; ENZYME INHIBITION; ENZYME INHIBITOR COMPLEX; ENZYME SPECIFICITY; GENE MUTATION; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; LIPOPHILICITY; MOLECULAR INTERACTION; MOLECULAR LIBRARY; MUTAGENICITY; REVIEW; STRUCTURE ACTIVITY RELATION; VIRUS MUTATION; VIRUS RESISTANCE;

ACQUIRED IMMUNODEFICIENCY SYNDROME; ALLOSTERIC SITE; ANTI-HIV AGENTS; BENZODIAZEPINES; BENZOPHENONES; DRUG RESISTANCE, VIRAL; IMIDAZOLES; PYRIDONES; PYRIMIDINES; REVERSE TRANSCRIPTASE INHIBITORS;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 68149096920     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2009.06.060     Document Type: Review

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