New arylpyrido-diazepine and -thiodiazepine derivatives are potent and highly selective HIV-1 inhibitors targeted at the reverse transcriptase

Antiviral Research

Volumn 30, Issue 2-3, 1996, Pages 109-124

  Bellarosa, D ^a,c   Antonelli, G ^b   Bambacioni, F ^a   Giannotti, D ^c   Viti, G ^c   Nannicini, R ^c   Giachetti, A ^c   Dianzani, F ^a   Witvrouw, M ^d   Pauwels, R ^d   Desmyter, J ^d   De Clercq, E ^d  

^a SAPIENZA UNIVERSITY OF ROME   (Italy)

^b UNIVERSITY OF PISA   (Italy)

^c Menarini Ricerche SpA   (Italy)

^d REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

Author keywords

HIV; Non nucleoside reverse transcriptase inhibitors

Indexed keywords

9 CHLORO 4,5,6,7 TETRAHYDRO 5 METHYL 6 (3 METHYL 2 BUTENYL)IMIDAZO[4,5,1 JK][1,4]BENZODIAZEPINE 2(1H) THIONE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; ARYLPYRIDODIAZEPINE DERIVATIVE; ARYLPYRIDOTHIODIAZEPINE DERIVATIVE; DEXTRAN SULFATE; DIDANOSINE; MEN 10597; MEN 10610; MEN 10683; MEN 10690; MEN 10704; MEN 10789; MEN 10880; MEN 10977; MEN 10979; MEN 10992; MEN 11006; MEN 11009; MEN 11016; MEN 11017; NEVIRAPINE; NEW DRUG; RNA DIRECTED DNA POLYMERASE; RNA DIRECTED DNA POLYMERASE INHIBITOR; SAQUINAVIR; UNCLASSIFIED DRUG; VIRUS ENZYME; ZIDOVUDINE;

ANTIVIRAL ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOTOXICITY; DRUG POTENTIATION; DRUG RESISTANCE; HERPES SIMPLEX VIRUS; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2; PRIORITY JOURNAL; SIMIAN IMMUNODEFICIENCY VIRUS; VIRUS REPLICATION;

HERPES; HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 2; SIMIAE; SIMIAN IMMUNODEFICIENCY VIRUS; SIMPLEXVIRUS;

EID: 0029893162     PISSN: 01663542     EISSN: None     Source Type: Journal    
DOI: 10.1016/0166-3542(95)00906-X     Document Type: Article

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