Crystal structures of HIV-1 reverse transcriptase in complex with carboxanilide derivatives

Biochemistry

Volumn 37, Issue 41, 1998, Pages 14394-14403

  Ren, Jingshan ^a   Esnouf, Robert M ^b   Hopkins, Andrew L ^a   Warren, Jonathan ^a   Balzarini, Jan ^b   Stuart, David I ^a,c   Stammers, David K ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b REGA INSTITUTE FOR MEDICAL RESEARCH   (Belgium)

^c UNIVERSITY OF OXFORD   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ANILIDE; CARBOXANILIDE DERIVATIVE; RNA DIRECTED DNA POLYMERASE; UNCLASSIFIED DRUG;

ARTICLE; COMPLEX FORMATION; CRYSTAL STRUCTURE; DRUG RECEPTOR BINDING; ENZYME ACTIVE SITE; ENZYME ACTIVITY; ENZYME INHIBITOR COMPLEX; HUMAN IMMUNODEFICIENCY VIRUS 1; HYDROGEN BOND; NONHUMAN; POINT MUTATION; PRIORITY JOURNAL; PROTEIN DOMAIN; X RAY CRYSTALLOGRAPHY;

ANILIDES; ANTI-HIV AGENTS; BENZOATES; BINDING SITES; CARBOXIN; COMPUTER SIMULATION; CRYSTALLIZATION; CRYSTALLOGRAPHY, X-RAY; FURANS; HIV-1 REVERSE TRANSCRIPTASE; HUMANS; MODELS, MOLECULAR; PROTEIN CONFORMATION; REVERSE TRANSCRIPTASE INHIBITORS; STEREOISOMERISM; THIOCARBAMATES;

HUMAN IMMUNODEFICIENCY VIRUS; HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 0032514718     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi981309m     Document Type: Article

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