The benzylthio-pyrimidine U-31,355, a potent inhibitor of HIV-1 reverse transcriptase

Biochemical Pharmacology

Volumn 51, Issue 6, 1996, Pages 743-750

  Althaus, Irene W ^a   Chou, Kuo Chen ^a,b   Lemay, Richelle J ^a   Franks, Kellie M ^a   Deibel, Martin R ^a   Kezdy, Ferenc J ^a   Resnick, Lionel ^a,c   Busso, Mariano E ^a,d   So, Antero G ^a,d   Downey, Kathleen M ^a,d   Romero, Donna L ^a   Thomas, Richard C ^a   Aristoff, Paul A ^a   Tarpley, W Gary ^a   Reusser, Fritz ^a  

^a PFIZER INC   (United States)

^b Upjohn Laboratories ^*  (United States)

^c University of Miami ^*  (United States)

^d UNIVERSITY OF MIAMI   (United States)

Author keywords

HIV 1 reverse transcriptase; inhibition kinetics; non nucleoside inhibitors

Indexed keywords

4 AMINO 2 (BENZYLTHIO) 6 CHLOROPYRIMIDINE; ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; DEOXYNUCLEOSIDE TRIPHOSPHATE; POLYNUCLEOTIDE; RECOMBINANT ENZYME; RNA DIRECTED DNA POLYMERASE; RNA DIRECTED DNA POLYMERASE INHIBITOR; U 31355; UNCLASSIFIED DRUG;

ANTIVIRAL ACTIVITY; ARTICLE; CONCENTRATION RESPONSE; CONTROLLED STUDY; DRUG MECHANISM; ENZYME INHIBITION; ENZYME KINETICS; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; LYMPHOCYTE CULTURE; PRIORITY JOURNAL;

EID: 0029981307     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/0006-2952(95)02390-9     Document Type: Article

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