Mutation of amino acids in the connection domain of human immunodeficiency virus type 1 reverse transcriptase that contact the template-primer affects RNase H activity

Journal of Virology

Volumn 77, Issue 15, 2003, Pages 8548-8554

  Julias, John G ^a   McWilliams, Mary Jane ^a   Sarafianos, Stefan G ^b   Alvord, W Gregory ^a   Arnold, Edward ^b   Hughes, Stephen H ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

^b RUTGERS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; DOUBLE STRANDED DNA; PRIMER DNA; PRIMER RNA; RIBONUCLEASE H; RNA DIRECTED DNA POLYMERASE; VIRUS DNA; VIRUS VECTOR;

AMINO ACID SEQUENCE; ARTICLE; COMPLEX FORMATION; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME BINDING; ENZYME DEGRADATION; ENZYME SPECIFICITY; ENZYME STRUCTURE; GENE MUTATION; HUMAN IMMUNODEFICIENCY VIRUS 1; LONG TERMINAL REPEAT; NONHUMAN; PRIORITY JOURNAL; PROTEIN DOMAIN; VIRUS TITRATION;

AMINO ACID SEQUENCE; DNA PRIMERS; HIV-1 REVERSE TRANSCRIPTASE; HUMANS; MODELS, MOLECULAR; MUTATION; RIBONUCLEASE H, CALF THYMUS; RNA, VIRAL; TEMPLATES, GENETIC;

EID: 0038107748     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.77.15.8548-8554.2003     Document Type: Article

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