메뉴 건너뛰기




Volumn 41, Issue 4, 1997, Pages 831-837

Highly potent oxathiin carboxanilide derivatives with efficacy against nonnucleoside reverse transcriptase inhibitor-resistant human immunodeficiency virus isolates

Author keywords

[No Author keywords available]

Indexed keywords

DIDANOSINE; LAMIVUDINE; N [4 CHLORO 3 (3 METHYL 2 BUTENYLOXY)PHENYL] 2 METHYL 3 FURANCARBOTHIOAMIDE; N [4 CHLORO 3 (3 METHYL 2 BUTENYLOXY)PHENYL] 2 METHYL 3 THIOPHENECARBOTHIOAMIDE; OXATHIIN DERIVATIVE; RNA DIRECTED DNA POLYMERASE INHIBITOR; UC 040; UNCLASSIFIED DRUG; ZALCITABINE; ZIDOVUDINE;

EID: 8244226649     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/aac.41.4.831     Document Type: Article
Times cited : (40)

References (29)
  • 2
    • 0028940526 scopus 로고
    • Oxathiin carboxanilide derivatives: A class of nonnucleoside HIV-1-specific reverse transcriptase inhibitors (NNRTIs) that are active against mutant HIV-1 strains resistant to other NNRTIs
    • Balzarini, J., H. Jonckheere, W. A. Harrison, D. C. Dao, J. Anne, E. De Clercq, and A. Karlsson. 1995. Oxathiin carboxanilide derivatives: a class of nonnucleoside HIV-1-specific reverse transcriptase inhibitors (NNRTIs) that are active against mutant HIV-1 strains resistant to other NNRTIs. Antiviral Chem. Chemother. 6:169-178.
    • (1995) Antiviral Chem. Chemother. , vol.6 , pp. 169-178
    • Balzarini, J.1    Jonckheere, H.2    Harrison, W.A.3    Dao, D.C.4    Anne, J.5    De Clercq, E.6    Karlsson, A.7
  • 3
    • 0027412181 scopus 로고
    • Analysis of nonnucleoside drug-resistant variants of human immunodeficiency virus type 1 reverse transcriptase
    • Boyer, P. L., M. J. Currens, J. B. McMahon, M. R. Boyd, and S. H. Hughes. 1993. Analysis of nonnucleoside drug-resistant variants of human immunodeficiency virus type 1 reverse transcriptase. J. Virol. 67:2412-2420.
    • (1993) J. Virol. , vol.67 , pp. 2412-2420
    • Boyer, P.L.1    Currens, M.J.2    McMahon, J.B.3    Boyd, M.R.4    Hughes, S.H.5
  • 7
    • 0027424829 scopus 로고
    • Differential antiviral activity of two TIBO derivatives against the human immunodeficiency and murine leukemia viruses alone and in combination with other anti-HIV agents
    • Buckheit, R. W., Jr., J. Germany-Decker, M. G. Hollingshead, L. B. Allen, W. M. Shannon, P. A. Janssen, and M. A. Chirigos. 1993. Differential antiviral activity of two TIBO derivatives against the human immunodeficiency and murine leukemia viruses alone and in combination with other anti-HIV agents. AIDS Res. Hum. Retroviruses 9:1097-1106.
    • (1993) AIDS Res. Hum. Retroviruses , vol.9 , pp. 1097-1106
    • Buckheit Jr., R.W.1    Germany-Decker, J.2    Hollingshead, M.G.3    Allen, L.B.4    Shannon, W.M.5    Janssen, P.A.6    Chirigos, M.A.7
  • 11
    • 0026333212 scopus 로고
    • Characterization of the binding site for nevirapine (BI-RG-587), a nonnucleoside inhibitor of human immunodeficiency virus type-1 reverse transcriptase
    • Cohen, K. A., J. Hopkins, R. H. Ingraham, C. Pargellis, J. C. Wu, D. E. Palladino, P. Kinkade, T. C. Warren, S. Rogers, and J. Adams. 1991. Characterization of the binding site for nevirapine (BI-RG-587), a nonnucleoside inhibitor of human immunodeficiency virus type-1 reverse transcriptase. J. Biol. Chem. 266:14670-14674.
    • (1991) J. Biol. Chem. , vol.266 , pp. 14670-14674
    • Cohen, K.A.1    Hopkins, J.2    Ingraham, R.H.3    Pargellis, C.4    Wu, J.C.5    Palladino, D.E.6    Kinkade, P.7    Warren, T.C.8    Rogers, S.9    Adams, J.10
  • 12
    • 0026638419 scopus 로고
    • Identification of the human immunodeficiency virus reverse transcriptase residues that contribute to the activity of diverse nonnucleoside inhibitors
    • Condra, J. H., E. A. Emini, L. Gotlib, D. J. Graham, A. J. Schlabach, J. A. Wolfgang, R. J. Colonno, and V. V. Sardana. 1992. Identification of the human immunodeficiency virus reverse transcriptase residues that contribute to the activity of diverse nonnucleoside inhibitors. Antimicrob. Agents Chemother. 36:1441-1446.
    • (1992) Antimicrob. Agents Chemother. , vol.36 , pp. 1441-1446
    • Condra, J.H.1    Emini, E.A.2    Gotlib, L.3    Graham, D.J.4    Schlabach, A.J.5    Wolfgang, J.A.6    Colonno, R.J.7    Sardana, V.V.8
  • 13
    • 0029153101 scopus 로고
    • Synergistic inhibition of HIV-1 reverse transcriptase DNA polymerase activity and virus replication in vitro by combinations of carboxanilide non-nucleoside compounds
    • Fletcher, R. S., D. Arion, G. Borkow, M. A. Wainberg, G. I. Dmitrienko, and M. A. Parniak. 1995. Synergistic inhibition of HIV-1 reverse transcriptase DNA polymerase activity and virus replication in vitro by combinations of carboxanilide non-nucleoside compounds. Biochemistry 34:10106-10112.
    • (1995) Biochemistry , vol.34 , pp. 10106-10112
    • Fletcher, R.S.1    Arion, D.2    Borkow, G.3    Wainberg, M.A.4    Dmitrienko, G.I.5    Parniak, M.A.6
  • 14
    • 0028922944 scopus 로고
    • Carboxanilide derivative non-nucleoside inhibitors of HIV-1 reverse transcriptase interact with different mechanistic forms of the enzyme
    • Fletcher, R. S., K. Syed, S. Mithani, G. I. Dmitrienko, and M. A. Parniak. 1995. Carboxanilide derivative non-nucleoside inhibitors of HIV-1 reverse transcriptase interact with different mechanistic forms of the enzyme. Biochemistry 34:4346-4353.
    • (1995) Biochemistry , vol.34 , pp. 4346-4353
    • Fletcher, R.S.1    Syed, K.2    Mithani, S.3    Dmitrienko, G.I.4    Parniak, M.A.5
  • 17
    • 0028231995 scopus 로고
    • Protein binding of human immunodeficiency virus protease inhibitor KNI-272 and alteration of its in vitro antiretroviral activity in the presence of high concentrations of proteins
    • Kageyama, S., B. D. Anderson, B. L. Hoesterey, H. Hayashi, Y. Kiso, K. P. Flora, and H. Mitsuya. 1994. Protein binding of human immunodeficiency virus protease inhibitor KNI-272 and alteration of its in vitro antiretroviral activity in the presence of high concentrations of proteins. Antimicrob. Agents Chemother. 38:1107-1111.
    • (1994) Antimicrob. Agents Chemother. , vol.38 , pp. 1107-1111
    • Kageyama, S.1    Anderson, B.D.2    Hoesterey, B.L.3    Hayashi, H.4    Kiso, Y.5    Flora, K.P.6    Mitsuya, H.7
  • 19
    • 0029774789 scopus 로고    scopus 로고
    • Isolation and characterization of HIV-1 isolates resistant to oxathiin carboxanilide analogs: Evaluation of variables in the resistance selection process
    • Kinjerski, T. L., L. A. Pallansch, and R. W. Buckheit, Jr. 1996. Isolation and characterization of HIV-1 isolates resistant to oxathiin carboxanilide analogs: evaluation of variables in the resistance selection process. Antiviral Chem. Chemother. 7:261-269.
    • (1996) Antiviral Chem. Chemother. , vol.7 , pp. 261-269
    • Kinjerski, T.L.1    Pallansch, L.A.2    Buckheit Jr., R.W.3
  • 21
    • 0027376921 scopus 로고
    • Viral resistance to the thiazolo-iso-indolinones, a new class of nonnucleoside inhibitors of human immunodeficiency virus type 1 reverse transcriptase
    • Maass, G., U. Immendoerfer, B. Koenig, U. Leser, B. Mueller, R. Goody, and E. Pfaff. 1993. Viral resistance to the thiazolo-iso-indolinones, a new class of nonnucleoside inhibitors of human immunodeficiency virus type 1 reverse transcriptase. Antimicrob. Agents Chemother. 37:2612-2617.
    • (1993) Antimicrob. Agents Chemother. , vol.37 , pp. 2612-2617
    • Maass, G.1    Immendoerfer, U.2    Koenig, B.3    Leser, U.4    Mueller, B.5    Goody, R.6    Pfaff, E.7
  • 23
    • 0026579394 scopus 로고
    • In vitro selection and molecular characterization of human immunodeficiency virus-1 resistant to non-nucleoside inhibitors of reverse transcriptase
    • Erratum, 42:174
    • Mellors, J. W., G. E. Dutschman, G. J. Im, E. Tramontane, S. R. Winkler, and Y. C. Cheng. 1992. In vitro selection and molecular characterization of human immunodeficiency virus-1 resistant to non-nucleoside inhibitors of reverse transcriptase. Mol. Pharmacol. 41:446-451. (Erratum, 42:174.)
    • (1992) Mol. Pharmacol. , vol.41 , pp. 446-451
    • Mellors, J.W.1    Dutschman, G.E.2    Im, G.J.3    Tramontane, E.4    Winkler, S.R.5    Cheng, Y.C.6
  • 26
    • 0024993530 scopus 로고
    • A three-dimensional model to analyze drug-drug interactions
    • Prichard, M. N., and C. Shipman, Jr. 1990. A three-dimensional model to analyze drug-drug interactions. Antiviral Res. 14:181-206.
    • (1990) Antiviral Res. , vol.14 , pp. 181-206
    • Prichard, M.N.1    Shipman Jr., C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.