Anti-HIV-1 activity of thiadiazole derivatives: Structure-activity relationship, reverse transcriptase inhibition, and lipophilicity

Antiviral Research

Volumn 31, Issue 1-2, 1996, Pages 87-94

  Ijichi, Katsushi ^a   Fujiwara, Masatoshi ^a   Nagano, Hideki ^a   Matsumoto, Yukiharu ^a   Hanasaki, Yasuaki ^b   Ide, Teruhiko ^b   Katsuura, Kimio ^b   Takayama, Hiromitsu ^c   Shirakawa, Seiichiro ^c   Aimi, Norio ^c   Shigeta, Shiro ^d   Konno, Kenji ^a   Matsushima, Masaaki ^a   Yokota, Tomoyuki ^a   Baba, Masanori ^e  

^a Rational Drug Design Laboratories   (Japan)

^b TOSOH CORPORATION   (Japan)

^c CHIBA UNIVERSITY   (Japan)

^d FUKUSHIMA MEDICAL UNIVERSITY   (Japan)

^e KAGOSHIMA UNIVERSITY   (Japan)

Author keywords

HIV 1 specific reverse transcriptase inhibitor; Lipophilicity; NNRTI; Structure activity relationship; TDA derivatives

Indexed keywords

NEVIRAPINE; RNA DIRECTED DNA POLYMERASE; THIADIAZOLE DERIVATIVE; ZIDOVUDINE;

ANTIVIRAL ACTIVITY; ARTICLE; DRUG ACTIVITY; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; LIPOPHILICITY; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

EID: 19244377980     PISSN: 01663542     EISSN: None     Source Type: Journal    
DOI: 10.1016/0166-3542(96)00950-3     Document Type: Article

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