Atomistic details of the disordered states of KID and pKID. implications in coupled binding and folding

Journal of the American Chemical Society

Volumn 131, Issue 14, 2009, Pages 5214-5223

  Ganguly, Debabani ^a   Chen, Jianhan ^a  

^a KANSAS STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATOMISTIC SIMULATIONS; CONFORMATIONAL CHANGE; CONFORMATIONAL SPACE; CONFORMATIONAL SUBSTATES; CREB BINDING PROTEINS; DISORDERED PROTEINS; DISORDERED STATE; FORCE FIELDS; FUNCTIONAL PROTEINS; GENERALIZED BORN; HELICITIES; IMPLICIT SOLVENTS; LOOP REGIONS; MODELING FRAMEWORKS; OPTIMAL BALANCE; REPLICA EXCHANGE; SOLVENT BASED; STRUCTURAL DETAILS; TERTIARY LEVELS;

PHOSPHORYLATION; TRANSCRIPTION FACTORS;

PROTEIN FOLDING;

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN; PROTEIN; SERINE; CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; PHOSPHATE; PROTEIN BINDING;

ARTICLE; ATOM; BINDING KINETICS; CONFORMATIONAL TRANSITION; CONTROLLED STUDY; ENTROPY; FORCE; MOLECULAR RECOGNITION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FOLDING; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SIMULATION; AMINO ACID SEQUENCE; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; GENETICS; METABOLISM; MOLECULAR GENETICS; MUTATION; PHOSPHORYLATION; PROTEIN TERTIARY STRUCTURE;

AMINO ACID SEQUENCE; COMPUTER SIMULATION; CREB-BINDING PROTEIN; CYCLIC AMP RESPONSE ELEMENT-BINDING PROTEIN; ENTROPY; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MUTATION; PHOSPHATES; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STRUCTURE, TERTIARY;

EID: 67849122622     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja808999m     Document Type: Article

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