Molecular dynamics simulations and free energy analyses on the dimer formation of an amyloidogenic heptapeptide from human β2-microglobulin: Implication for the protofibril structure

Journal of Molecular Biology

Volumn 356, Issue 4, 2006, Pages 1049-1063

  Lei, Hongxing ^a   Wu, Chun ^a   Wang, Zhixiang ^a   Duan, Yong ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Amyloid protofibril filament; Molecular dynamics simulation; Protein aggregation; Protein folding; 2 microglobulin

Indexed keywords

AMYLOID PROTEIN; BETA 2 MICROGLOBULIN; GLUTAMINYLVALYLLEUCYLHISTIDYLTHREONYLSERYLASPARAGININE; HEPTAPEPTIDE; LYSYLHISTIDYLASPARTYLSERYLMETHIONYLALANYLGLUTAMIC ACID; UNCLASSIFIED DRUG;

ARTICLE; DIMERIZATION; ENERGY; ENTROPY; HYDROGEN BOND; HYDROPHOBICITY; MOLECULAR DYNAMICS; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN INTERACTION; WILD TYPE;

EID: 31344481845     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2005.11.087     Document Type: Article

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