Determinants of catalytic power and ligand binding in glutamate racemase

Journal of the American Chemical Society

Volumn 131, Issue 14, 2009, Pages 5274-5284

  Spies, M Ashley ^a,b,c,d   Reese, Joseph G ^a,b,c,d   Dodd, Dylan ^a,b,c,d   Pankow, Katherine L ^a,b,c,d   Blanke, Steven R ^a,b,c,d   Baudry, Jerome ^a,b,c  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b UNIVERSITY OF TENNESSEE   (United States)

^c OAK RIDGE NATIONAL LABORATORY   (United States)

^d UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVE SITE; ANTIBACTERIAL AGENT; BACILLUS SUBTILIS; CARBANION COMPLEXES; CATALYTIC POWER; COFACTOR; ELECTROSTATIC INTERACTIONS; ENZYME-LIGAND INTERACTIONS; EXPERIMENTAL STUDIES; HIGH AFFINITY LIGANDS; IN-SILICO; INTERACTION ENERGIES; L-GLUTAMATE; LIGAND BINDING; PEPTIDOGLYCAN; PROTON ABSTRACTION; RACEMASE; SITE DIRECTED MUTAGENESIS; STEREOINVERSION; TIGHT BINDING;

AMINES; AMINO ACIDS; BACTERIOLOGY; BINDING ENERGY; BIOCHEMICAL ENGINEERING; BIOCHEMISTRY; CHROMIUM COMPOUNDS; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYMES; HYDROGEN; IONS; LIGANDS; ORGANIC ACIDS; SUBSTRATES;

HYDROGEN BONDS;

CARBON; CARBOXYLIC ACID; DEXTRO GLUTAMIC ACID; GLUTAMATE CARBANION; GLUTAMATE RACEMASE; GLUTAMIC ACID; HYDROGEN; LIGAND; PROTON; RACEMASE; UNCLASSIFIED DRUG; BACTERIAL PROTEIN; ISOMERASE; PROTEIN BINDING;

ARTICLE; BACILLUS SUBTILIS; CATALYSIS; COMPUTER MODEL; CRYSTAL STRUCTURE; ELECTRICITY; ENERGY; HYDROGEN BOND; LIGAND BINDING; MUTAGENESIS; NONHUMAN; PROTEIN INTERACTION; SITE DIRECTED MUTAGENESIS; CHEMICAL STRUCTURE; CHEMISTRY; COMPUTER SIMULATION; ENZYME SPECIFICITY; ENZYMOLOGY; ESCHERICHIA COLI; GENETICS; ISOLATION AND PURIFICATION; KINETICS; METABOLISM; PROTEIN CONFORMATION; THERMODYNAMICS;

AMINO ACID ISOMERASES; BACILLUS SUBTILIS; BACTERIAL PROTEINS; COMPUTER SIMULATION; ESCHERICHIA COLI; GLUTAMIC ACID; KINETICS; LIGANDS; MODELS, MOLECULAR; MUTAGENESIS, SITE-DIRECTED; PROTEIN BINDING; PROTEIN CONFORMATION; SUBSTRATE SPECIFICITY; THERMODYNAMICS;

EID: 67749103829     PISSN: 00027863     EISSN: None     Source Type: Journal    
DOI: 10.1021/ja809660g     Document Type: Article

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