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Volumn 136, Issue 7, 2009, Pages 723-735

Searching for virulence factors in the non-pathogenic parasite to humans Leishmania tarentolae

Author keywords

Leishmania infantum; Leishmania major; Leishmania tarentolae; Non pathogenic; Pathogenic; Virulence factors

Indexed keywords

CYSTEINE PROTEASE B; LIPOPHOSPHOGLYCAN; LIPOPHOSPHOGLYCAN 3; MICROBIAL ENZYME; PROTEIN A2; PROTEIN GP63; PROTOZOAL PROTEIN; UNCLASSIFIED DRUG; VIRULENCE FACTOR; MESSENGER RNA; PROTOZOAL DNA;

EID: 67651183810     PISSN: 00311820     EISSN: 14698161     Source Type: Journal    
DOI: 10.1017/S0031182009005873     Document Type: Article
Times cited : (36)

References (70)
  • 1
    • 2342467942 scopus 로고    scopus 로고
    • Expression profiling using random genomic DNA microarrays identifies differentially expressed genes associated with three major developmental stages of the protozoan parasite Leishmania major
    • Akopyants, N. S., Matlib, R. S., Bukanova, E. N., Smeds, M. R., Brownstein, B. H., Stormo, G. D. and Beverley, S. M. (2004). Expression profiling using random genomic DNA microarrays identifies differentially expressed genes associated with three major developmental stages of the protozoan parasite Leishmania major. Molecular and Biochemical Parasitology 136, 71-86.
    • (2004) Molecular and Biochemical Parasitology , vol.136 , pp. 71-86
    • Akopyants, N.S.1    Matlib, R.S.2    Bukanova, E.N.3    Smeds, M.R.4    Brownstein, B.H.5    Stormo, G.D.6    Beverley, S.M.7
  • 2
    • 0032534577 scopus 로고    scopus 로고
    • Leishmania mexicana cysteine proteinase-deficient mutants have attenuated virulence for mice and potentiate a Th1 response
    • Alexander, J., Coombs, G. H. and Mottram, J. C. (1998). Leishmania mexicana cysteine proteinasedeficient mutants have attenuated virulence for mice and potentiate a Th1 response. Journal of Immunology 161, 6794-6801. (Pubitemid 28562223)
    • (1998) Journal of Immunology , vol.161 , Issue.12 , pp. 6794-6801
    • Alexander, J.1    Coombs, G.H.2    Mottram, J.C.3
  • 3
    • 0023193846 scopus 로고
    • The promastigote surface protease of Leishmania
    • Bordier, C. (1987). The promastigote surface protease of Leishmania. Parsitology Today 3, 151-153.
    • (1987) Parsitology Today , vol.3 , pp. 151-153
    • Bordier, C.1
  • 4
    • 25444511090 scopus 로고    scopus 로고
    • Live nonpathogenic parasitic vector as a candidate vaccine against visceral leishmaniasis
    • DOI 10.1128/IAI.73.10.6372-6382.2005
    • Breton, M., Tremblay, M. J., Ouellette, M. and Papadopoulou, B. (2005). Live nonpathogenic parasitic vector as a candidate vaccine against visceral leishmaniasis. Infection and Immunity 73, 6372-6382. (Pubitemid 41368798)
    • (2005) Infection and Immunity , vol.73 , Issue.10 , pp. 6372-6382
    • Breton, M.1    Tremblay, M.J.2    Ouellette, M.3    Papadopoulou, B.4
  • 5
    • 0141955100 scopus 로고    scopus 로고
    • Cysteine protease B of Leishmania mexicana inhibits host Th1 responses and protective immunity
    • Buxbaum, L. U., Denise, H., Coombs, G. H., Alexander, J., Mottram, J. C. and Scott, P. (2003). Cysteine protease B of Leishmania mexicana inhibits host Th1 responses and protective immunity. Journal of Immunology 171, 3711-3717. (Pubitemid 37254576)
    • (2003) Journal of Immunology , vol.171 , Issue.7 , pp. 3711-3717
    • Buxbaum, L.U.1    Denise, H.2    Coombs, G.H.3    Alexander, J.4    Mottram, J.C.5    Scott, P.6
  • 6
    • 4344613395 scopus 로고    scopus 로고
    • Inhibition of lipopolysaccharide-induced macrophage IL-12 production by Leishmania mexicana amastigotes: The role of cysteine peptidases and the NF-kappaB signaling pathway
    • Cameron, P., McGachy, A., Anderson, M., Paul, A., Coombs, G. H., Mottram, J. C., Alexander, J. and Plevin, R. (2004). Inhibition of lipopolysaccharideinduced macrophage IL-12 production by Leishmania mexicana amastigotes: the role of cysteine peptidases and the NF-kappaB signaling pathway. Journal of Immunology 173, 3297-3304. (Pubitemid 39142038)
    • (2004) Journal of Immunology , vol.173 , Issue.5 , pp. 3297-3304
    • Cameron, P.1    McGachy, A.2    Anderson, M.3    Paul, A.4    Coombs, G.H.5    Mottram, J.C.6    Alexander, J.7    Plevin, R.8
  • 7
    • 0026672806 scopus 로고
    • Identification of a gp63 surface glycoprotein in Leishmania tarentolae
    • Campbell, D., Kurath, U. and Fleischmann, J. (1992). Identification of a gp63 surface glycoprotein in Leishmania tarentolae. FEMS Microbiology Letters 75, 89-92.
    • (1992) FEMS Microbiology Letters , vol.75 , pp. 89-92
    • Campbell, D.1    Kurath, U.2    Fleischmann, J.3
  • 8
    • 0033966027 scopus 로고    scopus 로고
    • Episomal expression of specific sense and antisense mRNAs in Leishmania amazonensis: Modulation of gp63 level in promastigotes and their infection of macrophages in vitro
    • Chen, D. Q., Kolli, B. K., Yadava, N., Lu, H. G., Gilman-Sachs, A., Peterson, D. A. and Chang, K-P. (2000). Episomal expression of specific sense and antisense mRNAs in Leishmania amazonensis: modulation of gp63 level in promastigotes and their infection of macrophages in vitro. Infection and Immunity 68, 80-86. (Pubitemid 30016680)
    • (2000) Infection and Immunity , vol.68 , Issue.1 , pp. 80-86
    • Chen, D.-Q.1    Kolli, B.K.2    Yadava, N.3    Lu, H.G.4    Gilman-Sachs, A.5    Peterson, D.A.6    Chang, K.-P.7
  • 10
    • 0030866388 scopus 로고    scopus 로고
    • Evolution of the genus Leishmania revealed by comparison of DNA and RNA polymerase gene sequences
    • Croan, D. G., Morrison, D. A. and Ellis, J. T. (1997). Evolution of the genus Leishmania revealed by comparison of DNA and RNA polymerase gene sequences. Molecular and Biochemical Parasitology 89, 149-159.
    • (1997) Molecular and Biochemical Parasitology , vol.89 , pp. 149-159
    • Croan, D.G.1    Morrison, D.A.2    Ellis, J.T.3
  • 11
    • 0037009446 scopus 로고    scopus 로고
    • Leishmania LPG3 encodes a GRP94 homolog required for phosphoglycan synthesis implicated in parasite virulence but not viability
    • DOI 10.1093/emboj/cdf447
    • Descoteaux, A., Avila, H. A., Zhang, K., Turco, S. J. and Beverley, S. M. (2002). Leishmania LPG3 encodes a GRP94 homolog required for phosphoglycan synthesis implicated in parasite virulence but not viability. The EMBO Journal 21, 4458-4469. (Pubitemid 34984333)
    • (2002) EMBO Journal , vol.21 , Issue.17 , pp. 4458-4469
    • Descoteaux, A.1    Avila, H.A.2    Zhang, K.3    Turco, S.J.4    Beverley, S.M.5
  • 12
    • 3042555141 scopus 로고    scopus 로고
    • Leishmaniasis: Current situation and new perspectives
    • DOI 10.1016/j.cimid.2004.03.004, PII S0147957104000232
    • Desjeux, P. (2004). Leishmaniasis: current situation and new perspectives. Comparative Immunology, Microbiology and Infectious Diseases 27, 305-318. (Pubitemid 38842803)
    • (2004) Comparative Immunology, Microbiology and Infectious Diseases , vol.27 , Issue.5 , pp. 305-318
    • Desjeux, P.1
  • 13
    • 33645804408 scopus 로고    scopus 로고
    • Mayday - A Microarray Data Analysis Workbench
    • Dietzsch, J., Gehlenborg, N. and Nieselt, K. (2006). Mayday - a Microarray Data Analysis Workbench. Bioinformatics 22, 1010-1012.
    • (2006) Bioinformatics , vol.22 , pp. 1010-1012
    • Dietzsch, J.1    Gehlenborg, N.2    Nieselt, K.3
  • 14
    • 0015882029 scopus 로고
    • Leismania adleri: In vitro phagocytosis by lizard leukocytes and peritoneal cells
    • Dollahon, N. R. and Janovy, J. (1973). Leismania adleri : in vitro phagocytosis by lizard leukocytes and peritoneal cells. Experimental Parasitology 34, 56-61.
    • (1973) Experimental Parasitology , vol.34 , pp. 56-61
    • Dollahon, N.R.1    Janovy, J.2
  • 15
    • 0033820138 scopus 로고    scopus 로고
    • Analysis of the roles of cysteine proteinases of Leishmania mexicana in the host-parasite interaction
    • Frame, M. J., Mottram, J. C. and Coombs, G. H. (2000). Analysis of the roles of cysteine proteinases of Leishmania mexicana in the host-parasite interaction. Parasitology 121, 367-377.
    • (2000) Parasitology , vol.121 , pp. 367-377
    • Frame, M.J.1    Mottram, J.C.2    Coombs, G.H.3
  • 16
    • 0033970867 scopus 로고    scopus 로고
    • Synergistic effects of IL-4 and IL-18 on IL-12-dependent IFN-gamma production by dendritic cells
    • Fukao, T., Matsuda, S. and Koyasu, S. (2000). Synergistic effects of IL-4 and IL-18 on IL-12- dependent IFN-gamma production by dendritic cells. Journal of Immunology 164, 64-71. (Pubitemid 30012973)
    • (2000) Journal of Immunology , vol.164 , Issue.1 , pp. 64-71
    • Fukao, T.1    Matsuda, S.2    Koyasu, S.3
  • 17
    • 25444482154 scopus 로고    scopus 로고
    • A2 gene of Old World cutaneous Leishmania is a single highly conserved functional gene
    • DOI 10.1186/1471-2334-5-18
    • Garin, Y. J., Meneceur, P., Pratlong, F., Dedet, J. P., Derouin, F. and Lorenzo, F. (2005). A2 gene of Old World cutaneous Leishmania is a single highly conserved functional gene. BMC Infectious Disease 28, 18. (Pubitemid 41363808)
    • (2005) BMC Infectious Diseases , vol.5 , pp. 18
    • Garin, Y.J.F.1    Meneceur, P.2    Pratlong, F.3    Dedet, J.-P.4    Derouin, F.5    Lorenzo, F.6
  • 18
    • 38749130506 scopus 로고    scopus 로고
    • A protein of the leucine-rich repeats (LRRs) superfamily is implicated in antimony resistance in Leishmania infantum amastigotes
    • DOI 10.1016/j.molbiopara.2007.11.008, PII S0166685107003143
    • Genest, P. A., Haimeur, A., Légaré , D., Sereno, D., Roy, G., Messier, N., Papadopoulou, B. and Ouellette, M. (2008). A protein of the leucine-rich repeats (LRRs) superfamily is implicated in antimony resistance in Leishmania infantum amastigotes. Molecular and Biochemical Parasitology 158, 95-99. (Pubitemid 351181236)
    • (2008) Molecular and Biochemical Parasitology , vol.158 , Issue.1 , pp. 95-99
    • Genest, P.-A.1    Haimeur, A.2    Legare, D.3    Sereno, D.4    Roy, G.5    Messier, N.6    Papadopoulou, B.7    Ouellette, M.8
  • 19
    • 0042351392 scopus 로고    scopus 로고
    • A2rel: A constitutively expressed Leishmania gene linked to an amastigote-stage-specific gene
    • DOI 10.1016/S0166-6851(98)00027-9, PII S0166685198000279
    • Ghedin, E., Charest, H. and Matlashewski, G. (1998). A2rel: a constitutively expressed Leishmania gene linked to an amastigote-stage-specific gene. Molecular and Biochemical Parasitology 93, 23-29. (Pubitemid 28252226)
    • (1998) Molecular and Biochemical Parasitology , vol.93 , Issue.1 , pp. 23-29
    • Ghedin, E.1    Charest, H.2    Matlashewski, G.3
  • 20
    • 0017137042 scopus 로고
    • Activities of glucose-6-phosphate, 6-phosphogluconate, and isocitrate dehydrogenases from Leishmania donovani cultivated at 25 and 37 C
    • Ghosh, D. K. and Honigberg, B. M. (1976). Activities of glucose-6-phosphate, 6-phosphogluconate, and isocitrate dehydrogenases from Leishmania donovani cultivated at 25 and 37 C. Journal of Parasitology 23, 450-455.
    • (1976) Journal of Parasitology , vol.23 , pp. 450-455
    • Ghosh, D.K.1    Honigberg, B.M.2
  • 21
    • 44849118269 scopus 로고    scopus 로고
    • A novel form of NF-kB is induced by Leishmania infection: Involvement in macrophage gene expression
    • Gregory, D. J., Godbout, M., Contreras, I., Forget, G. and Olivier, M. (2008). A novel form of NF-kB is induced by Leishmania infection: involvement in macrophage gene expression. European Journal of Immunology 38, 1071-1081.
    • (2008) European Journal of Immunology , vol.38 , pp. 1071-1081
    • Gregory, D.J.1    Godbout, M.2    Contreras, I.3    Forget, G.4    Olivier, M.5
  • 22
    • 33846821807 scopus 로고    scopus 로고
    • Specific cpb copies within the Leishmania donovani complex: Evolutionary interpretations and potential clinical implications in humans
    • Hide, M., Bras-Goncalves, R. and Banœ uls, A.-L. (2007). Specific cpb copies within the Leishmania donovani complex: evolutionary interpretations and potential clinical implications in humans. Parasitology 134, 379-389.
    • (2007) Parasitology , vol.134 , pp. 379-389
    • Hide, M.1    Bras-Goncalves, R.2    Banœ Uls, A.-L.3
  • 23
    • 0034595204 scopus 로고    scopus 로고
    • Lipophosphoglycan is not required for infection of macrophages or mice by Leishmania mexicana
    • Ilg, T. (2000). Lipophosphoglycan is not required for infection of macrophages or mice by Leishmania mexicana. The EMBO Journal 19, 1953-1962. (Pubitemid 30237571)
    • (2000) EMBO Journal , vol.19 , Issue.9 , pp. 1953-1962
    • Ilg, T.1
  • 25
    • 0015416332 scopus 로고
    • Temperature and metabolism in Leishmania. 3. Some dehydrogenases of L. donovani, L. mexicana, and L. tarentolae
    • Janovy, J. (1972). Temperature and metabolism in Leishmania. 3. Some dehydrogenases of L. donovani, L. mexicana, and L. tarentolae. Experimental Parasitology 32, 196-205.
    • (1972) Experimental Parasitology , vol.32 , pp. 196-205
    • Janovy, J.1
  • 27
    • 0035910270 scopus 로고    scopus 로고
    • Predicting transmembrane protein topology with a hidden Markov model: Application to complete genomes
    • DOI 10.1006/jmbi.2000.4315
    • Krogh, A., Larsson, B., von Heijne, G. and Sonnhammer, E. L. (2001). Predicting transmembrane protein topology with a hidden Markov model: application to complete genomes. Journal of Molecular Biology 19, 567-580. (Pubitemid 33032862)
    • (2001) Journal of Molecular Biology , vol.305 , Issue.3 , pp. 567-580
    • Krogh, A.1    Larsson, B.2    Von Heijne, G.3    Sonnhammer, E.L.L.4
  • 29
    • 0033759568 scopus 로고    scopus 로고
    • Leishmania infantum: Gene cloning of the GRP94 homologue, its expression as recombinant protein, and analysis of antigenicity
    • DOI 10.1006/expr.2000.4553
    • Larreta, R., Soto, M., Alonso, C. and Requena, J. M. (2000). Leishmania infantum: gene cloning of the GRP94 homologue, its expression as recombinant protein and analysis of antigenicity. Experimental Parasitology 96, 108-115. (Pubitemid 30818896)
    • (2000) Experimental Parasitology , vol.96 , Issue.2 , pp. 108-115
    • Larreta, R.1    Soto, M.2    Alonso, C.3    Requena, J.M.4
  • 30
    • 33846202033 scopus 로고    scopus 로고
    • Genomic and proteomic expression analysis of Leishmania promastigote and amastigote life stages. The Leishmania genome is constitutively expressed
    • Leifso, K., Cohen-Freue, G., Dogra, N., Murray, A. and McMaster, W. R. (2007). Genomic and proteomic expression analysis of Leishmania promastigote and amastigote life stages. The Leishmania genome is constitutively expressed. Molecular and Biochemical Parasitology 152, 35-46.
    • (2007) Molecular and Biochemical Parasitology , vol.152 , pp. 35-46
    • Leifso, K.1    Cohen-Freue, G.2    Dogra, N.3    Murray, A.4    McMaster, W.R.5
  • 31
    • 0028209204 scopus 로고
    • Evolution of RNA editing in kinetoplastid protozoa
    • DOI 10.1038/368345a0
    • Maslov, D. A., Avila, H. A., Lake, J. A. and Simpson, L. (1994). Evolution of RNA editing in kinetoplastid protozoa. Nature, London 368, 345-348. (Pubitemid 24104270)
    • (1994) Nature , vol.368 , Issue.6469 , pp. 345-348
    • Maslov, D.A.1    Avila, H.A.2    Lake, J.A.3    Simpson, L.4
  • 32
    • 0037088686 scopus 로고    scopus 로고
    • Extracellular release of the glycosylphosphatidylinositol (GPI)-linked Leishmania surface metalloprotease, gp63, is independent of GPI phospholipolysis: Implications for parasite virulence
    • McGwire, B. S., O'Connell, W. A., Chang, K. P. and Engman, D. M. (2002). Extracellular release of the glycosylphosphatidylinositol (GPI)-linked Leishmania surface metalloprotease, gp63, is independent of GPI phospholipolysis: implications for parasite virulence. Journal of Biological Chemistry 277, 8802-8809.
    • (2002) Journal of Biological Chemistry , vol.277 , pp. 8802-8809
    • McGwire, B.S.1    O'Connell, W.A.2    Chang, K.P.3    Engman, D.M.4
  • 33
    • 0027982197 scopus 로고
    • Mutational and functional analysis of the Leishmania surface metalloproteinase GP63: Similarities to matrix metalloproteinases
    • McMaster, W. R., Morrison, C. J., MacDonald, M. H. and Joshi, P. B. (1994). Mutational and functional analysis of the Leishmania surface metalloproteinase GP63: similarities to matrix metalloproteinases. Parasitology 108, S29-S36.
    • (1994) Parasitology , vol.108
    • McMaster, W.R.1    Morrison, C.J.2    MacDonald, M.H.3    Joshi, P.B.4
  • 34
    • 33745725868 scopus 로고    scopus 로고
    • A combined proteomic and transcriptomic approach to the study of stage differentiation in Leishmania infantum
    • DOI 10.1002/pmic.200500853
    • McNicoll, F., Drummelsmith, J., Muller, M., Madore, E., Boilard, N., Ouellette, M. and Papadopoulou, B. (2006). A combined proteomic and transcriptomic approach to the study of stage differentiation in Leishmania infantum. Proteomics 6, 3567-3581. (Pubitemid 44000186)
    • (2006) Proteomics , vol.6 , Issue.12 , pp. 3567-3581
    • McNicoll, F.1    Drummelsmith, J.2    Muller, M.3    Madore, E.4    Boilard, N.5    Ouellette, M.6    Papadopoulou, B.7
  • 35
    • 27444434267 scopus 로고    scopus 로고
    • Distinct 3k-untranslated region elements regulate stage-specific mRNA accumulation and translation in Leishmania
    • DOI 10.1074/jbc.M507511200
    • McNicoll, F., Muller, M., Cloutier, S., Boilard, N., Rochette, A., Dube, M. and Papadopoulou, B. (2005). Distinct 3k-untranslated region elements regulate stage-specific mRNA accumulation and translation in Leishmania. Journal of Biological Chemistry 280, 35238-35246. (Pubitemid 41532711)
    • (2005) Journal of Biological Chemistry , vol.280 , Issue.42 , pp. 35238-35246
    • McNicoll, F.1    Muller, M.2    Cloutier, S.3    Boilard, N.4    Rochette, A.5    Dube, M.6    Papadopoulou, B.7
  • 36
    • 0027466501 scopus 로고
    • Evolution and expression of the Leishmania surface proteinase (gp63) gene locus
    • Medina-Acosta, E., Beverley, S. M. and Russell, D. G. (1993). Evolution and expression of the Leishmania surface proteinase (gp63) gene locus. Infectious Agents and Diseases 2, 25-34 (Pubitemid 23111833)
    • (1993) Infectious Agents and Disease , vol.2 , Issue.1 , pp. 25-34
    • Medina-Acosta, E.1    Beverley, S.M.2    Russell, D.G.3
  • 37
    • 0032129794 scopus 로고    scopus 로고
    • Roles of cysteine proteinases of trypanosomes and Leishmania in host-parasite interactions
    • Mottram, J. C., Brooks, D. R. and Coombs, G. H. (1998). Roles of cysteine proteinases of trypanosomes and Leishmania in host-parasite interactions. Current Opinion in Microbiology 1, 455-460.
    • (1998) Current Opinion in Microbiology , vol.1 , pp. 455-460
    • Mottram, J.C.1    Brooks, D.R.2    Coombs, G.H.3
  • 39
    • 0037045399 scopus 로고    scopus 로고
    • Genomic organization and functional expression of differentially regulated cysteine protease genes of Leishmania donovani complex
    • DOI 10.1016/S0378-1119(01)00851-4, PII S0378111901008514
    • Mundodi, V., Somanna, A., Farrell, P. J. and Gedamu, L. (2002). Genomic organization and functional expression of differentially regulated cysteine protease genes of Leishmania donovani complex. Gene 282, 257-265. (Pubitemid 34117582)
    • (2002) Gene , vol.282 , Issue.1-2 , pp. 257-265
    • Mundodi, V.1    Somanna, A.2    Farrell, P.J.3    Gedamu, L.4
  • 41
    • 1642472963 scopus 로고    scopus 로고
    • Humoral and cellular immune responses against Type I cysteine proteinase of Leishmania infantum are higher in asymptomatic than symptomatic dogs selected from a naturally infected population
    • DOI 10.1016/j.vetpar.2003.11.013
    • Nakhaee, A., Taheri, T., Taghikhani, M., Mohebali, M., Salmanian, A. H., Fasel, N. and Rafati, S. (2004). Humoral and cellular immune responses against type I cysteine proteinase of Leishmania infantum are higher in asymptomatic than symptomatic dogs selected from a naturally infected population. Veterinary Parasitology 119, 107-123. (Pubitemid 38121383)
    • (2004) Veterinary Parasitology , vol.119 , Issue.2-3 , pp. 107-123
    • Nakhaee, A.1    Taheri, T.2    Taghikhani, M.3    Mohebali, M.4    Salmanian, A.-H.5    Fasel, N.6    Rafati, S.7
  • 42
  • 43
    • 0036633054 scopus 로고    scopus 로고
    • Intergenic and external transcribed spacers of ribosomal RNA genes in lizard-infecting Leishmania: Molecular structure and phylogenetic relationship to mammalinfecting Leishmania in the subgenus Leishmania (Leishmania)
    • Orlando, T. C., Rubio, M. A., Sturm, N. R., Campbell, D. A. and Floeter-Winter, L. M. (2002). Intergenic and external transcribed spacers of ribosomal RNA genes in lizard-infecting Leishmania: molecular structure and phylogenetic relationship to mammalinfecting Leishmania in the subgenus Leishmania (Leishmania). Memórias do Instituto Oswaldo Cruz 97, 695-701.
    • (2002) Memórias Do Instituto Oswaldo Cruz , vol.97 , pp. 695-701
    • Orlando, T.C.1    Rubio, M.A.2    Sturm, N.R.3    Campbell, D.A.4    Floeter-Winter, L.M.5
  • 44
    • 34250863493 scopus 로고    scopus 로고
    • Selection of endogenous reference genes for gene expression analysis in Leishmania major developmental stages
    • DOI 10.1007/s00436-007-0491-1
    • Ouakad, M., Bahi-Jaber, N., Chenik, M., Dellagi, K. and Louzir, H. (2007a). Selection of endogenous reference genes for gene expression analysis in Leishmania major developmental stages. Parasitology Research 101, 473-477. (Pubitemid 46980536)
    • (2007) Parasitology Research , vol.101 , Issue.2 , pp. 473-477
    • Ouakad, M.1    Bahi-Jaber, N.2    Chenik, M.3    Dellagi, K.4    Louzir, H.5
  • 45
    • 33845438028 scopus 로고    scopus 로고
    • Gene expression analysis of wild Leishmania major isolates: Identification of genes preferentially expressed in amastigotes
    • DOI 10.1007/s00436-006-0277-x
    • Ouakad, M., Chenik, M., Achour-Chenik, Y. B., Louzir, H. and Dellagi, K. (2007b). Gene expression analysis of wild Leishmania major isolates : identification of genes preferentially expressed in amastigotes. Parasitology Research 100, 255-264. (Pubitemid 44900259)
    • (2007) Parasitology Research , vol.100 , Issue.2 , pp. 255-264
    • Ouakad, M.1    Chenik, M.2    Ben Achour-Chenik, Y.3    Louzir, H.4    Dellagi, K.5
  • 48
    • 0030854605 scopus 로고    scopus 로고
    • Leishmania adleri a lizard parasite, expresses structurally similar glycoinositolphospholipids to mammalian Leishmania
    • DOI 10.1093/glycob/7.5.687
    • Previato, J. O., Jones, C., Wait, R., Routier, F., Saraiva, E. and Mendonça-Previato, L. (1997). Leishmania adleri, a lizard parasite, expresses structurally similar glycoinositolphospholipids to mammalian Leishmania. Glycobiology 7, 687-695. (Pubitemid 27308496)
    • (1997) Glycobiology , vol.7 , Issue.5 , pp. 687-695
    • Previato, J.O.1    Jones, C.2    Wait, R.3    Routier, F.4    Saraiva, E.5    Mendonca-Previato, L.6
  • 49
    • 33750360882 scopus 로고    scopus 로고
    • Amastin peptide-binding antibodies as biomarkers of active human visceral leishmaniasis
    • DOI 10.1128/CVI.00188-06
    • Rafati, S., Hassani, N., Taslimi, Y., Movassagh, H., Rochette, A. and Papadopoulou, B. (2006). Amastin peptide-binding antibodies as biomarkers of active human visceral leishmaniasis. Clinical Vaccine Immunology 13, 1104-1110. (Pubitemid 44622537)
    • (2006) Clinical and Vaccine Immunology , vol.13 , Issue.10 , pp. 1104-1110
    • Rafati, S.1    Hassani, N.2    Taslimi, Y.3    Movassagh, H.4    Rochette, A.5    Papadopoulou, B.6
  • 50
    • 0041669532 scopus 로고    scopus 로고
    • Expression of cysteine proteinase type I and II of Leishmania infantum and their recognition by sera during canine and human visceral leishmaniasis
    • DOI 10.1016/S0014-4894(03)00097-3
    • Rafati, S., Nakhaee, A., Taheri, T., Ghashghaii, A., Salmanian, A. H., Jimenez, M., Mohebali, M., Masina, S. and Fasel, N. (2003). Expression of cysteine proteinase type I and II of Leishmania infantum and their recognition by sera during canine and human visceral leishmaniasis. Experimental Parasitology 103, 143-151. (Pubitemid 36918189)
    • (2003) Experimental Parasitology , vol.103 , Issue.3-4 , pp. 143-151
    • Rafati, S.1    Nakhaee, A.2    Taheri, T.3    Ghashghaii, A.4    Salmanian, A.-H.5    Jimenez, M.6    Mohebali, M.7    Masina, S.8    Fasel, N.9
  • 51
    • 21044441505 scopus 로고    scopus 로고
    • Protective vaccination against experimental canine visceral leishmaniasis using a combination of DNA and protein immunization with cysteine proteinases type I and II of L. infantum
    • DOI 10.1016/j.vaccine.2005.02.009, PII S0264410X05002690
    • Rafati, S., Nakhaee, A., Taheri, T., Taslimi, Y., Darabi, H., Eravani, D., Sanos, S., Kaye, P., Taghikhani, M., Jamshidi, S. and Rad, M. A. (2005). Protective vaccination against experimental canine visceral leishmaniasis using a combination of DNA and protein immunization with cysteine proteinases type I and II of L. infantum. Vaccine 23, 3716-3725. (Pubitemid 40692418)
    • (2005) Vaccine , vol.23 , Issue.28 , pp. 3716-3725
    • Rafati, S.1    Nakhaee, A.2    Taheri, T.3    Taslimi, Y.4    Darabi, H.5    Eravani, D.6    Sanos, S.7    Kaye, P.8    Taghikhani, M.9    Jamshidi, S.10    Rad, M.A.11
  • 52
    • 0035089822 scopus 로고    scopus 로고
    • Identification of Leishmania major cysteine proteinases as targets of the immune response in humans
    • DOI 10.1016/S0166-6851(00)00377-7, PII S0166685100003777
    • Rafati, S., Salmanian, A. H., Hashemi, K., Schaff, C., Belli, S. and Fasel, N. (2001). Identification of Leishmania major cysteine proteinases as targets of the immune response in humans. Molecular and Biochemical Parasitology 113, 35-43. (Pubitemid 32209280)
    • (2001) Molecular and Biochemical Parasitology , vol.113 , Issue.1 , pp. 35-43
    • Rafati, S.1    Salmanian, A.-H.2    Hashemi, K.3    Schaff, C.4    Belli, S.5    Fasel, N.6
  • 53
    • 0034214297 scopus 로고    scopus 로고
    • Evolutionarily conserved proteins as prominent immunogens during Leishmania infections
    • DOI 10.1016/S0169-4758(00)01651-3, PII S0169475800016513
    • Requena, J. M., Alonso, C. and Soto, M. (2000). Evolutionarily conserved proteins as prominent immunogens during Leishmania infections. Parasitology Today 16, 246-250. (Pubitemid 30332127)
    • (2000) Parasitology Today , vol.16 , Issue.6 , pp. 246-250
    • Requena, J.M.1    Alonso, C.2    Soto, M.3
  • 54
    • 14744299083 scopus 로고    scopus 로고
    • Characterization and developmental gene regulation of a large gene family encoding amastin surface proteins in Leishmania spp
    • DOI 10.1016/j.molbiopara.2005.01.006
    • Rochette, A., McNicoll, F., Girard, J., Breton, M., Leblanc, E., Bergeron, M. G. and Papadopoulou, B. (2005). Characterization and developmental gene regulation of a large gene family encoding amastin surface proteins in Leishmania spp. Molecular and Biochemical Parasitology 140, 205-220. (Pubitemid 40332731)
    • (2005) Molecular and Biochemical Parasitology , vol.140 , Issue.2 , pp. 205-220
    • Rochette, A.1    McNicoll, F.2    Girard, J.3    Breton, M.4    Leblanc, E.5    Bergeron, M.G.6    Papadopoulou, B.7
  • 55
    • 47249134311 scopus 로고    scopus 로고
    • Genome-wide gene expression profiling analysis of Leishmania major and Leishmania infantum developmental stages reveals substantial differences between the two species
    • DOI 10.1186/1471-2164-9-255
    • Rochette, A., Raymond, F., Ubeda, J. M., Smith, M., Messier, N., Boisvert, S., Rigault, P., Corbeil, J., Ouellette, M. and Papadopoulou, B. (2008). Genome-wide gene expression profiling analysis of Leishmania major and Leishmania infantum developmental stages reveals substantial differences between the two species. BMC Genomics 9, 255-281. (Pubitemid 351984856)
    • (2008) BMC Genomics , vol.9 , pp. 255
    • Rochette, A.1    Raymond, F.2    Ubeda, J.-M.3    Smith, M.4    Messier, N.5    Boisvert, S.6    Rigault, P.7    Corbeil, J.8    Ouellette, M.9    Papadopoulou, B.10
  • 56
    • 0033042010 scopus 로고    scopus 로고
    • Proteases of protozoan parasites
    • Rosenthal, P. J. (1999). Proteases of protozoan parasites. Advances in Parasitology 43, 105-159.
    • (1999) Advances in Parasitology , vol.43 , pp. 105-159
    • Rosenthal, P.J.1
  • 57
    • 38949167477 scopus 로고    scopus 로고
    • Retooling Leishmania metabolism: From sand fly gut to human macrophage
    • DOI 10.1096/fj.07-9254com
    • Rosenzweig, D., Smith, D., Opperdoes, F., Stern, S., Olafson, R. W. and Zilberstein, D. (2008). Retooling Leishmania metabolism: from sand fly gut to human macrophage. The FASEB Journal 22, 590-602. (Pubitemid 351225595)
    • (2008) FASEB Journal , vol.22 , Issue.2 , pp. 590-602
    • Rosenzweig, D.1    Smith, D.2    Opperdoes, F.3    Stern, S.4    Olafson, R.W.5    Zilberstein, D.6
  • 58
    • 33646066009 scopus 로고    scopus 로고
    • Upregulation of surface proteins in Leishmania donovani isolated from patients of post kala-azar dermal leishmaniasis
    • Salotra, P., Duncan, R. C., Singh, R., Subba Raju, B. V., Sreenivas, G. and Nakhasi, H. L. (2006). Upregulation of surface proteins in Leishmania donovani isolated from patients of post kala-azar dermal leishmaniasis. Microbes and Infection 8, 637-644.
    • (2006) Microbes and Infection , vol.8 , pp. 637-644
    • Salotra, P.1    Duncan, R.C.2    Singh, R.3    Subba Raju, B.V.4    Sreenivas, G.5    Nakhasi, H.L.6
  • 61
  • 62
    • 0033369092 scopus 로고    scopus 로고
    • Genomic organization, transcription, splicing and gene regulation in Leishmania
    • Stiles, J. K., Hicock, P. I., Shah, P. H. and Mead, J. C. (1999). Genomic organization, transcription, splicing and gene regulation in Leishmania. Annals of Tropical Medicine and Parasitology 93, 781-807. (Pubitemid 30058078)
    • (1999) Annals of Tropical Medicine and Parasitology , vol.93 , Issue.8 , pp. 781-807
    • Stiles, J.K.1    Hicock, P.I.2    Shah, P.H.3    Meade, J.C.4
  • 63
    • 33748300634 scopus 로고    scopus 로고
    • Cysteine peptidases CPA and CPB are vital for autophagy and differentiation in Leishmania mexicana
    • DOI 10.1111/j.1365-2958.2006.05274.x
    • Williams, R. A., Tetley, L., Mottram, J. C. and Coombs, G. H. (2006).Cysteine peptidases CPA and CPB are vital for autophagy and differentiation in Leishmania mexicana. Molecular Microbiology 61, 655-674. (Pubitemid 44324091)
    • (2006) Molecular Microbiology , vol.61 , Issue.3 , pp. 655-674
    • Williams, R.A.1    Tetley, L.2    Mottram, J.C.3    Coombs, G.H.4
  • 64
    • 0033727540 scopus 로고    scopus 로고
    • A new developmentally regulated gene family in Leishmania amastigotes encoding a homolog of amastin surface proteins
    • DOI 10.1016/S0166-6851(00)00290-5, PII S0166685100002905
    • Wu, Y., El-Fakhry, Y., Sereno, D., Tamar, S. and Papadopoulou, B. (2000). A new developmentally regulated gene family in Leishmania amastigotes encoding a homolog of amastin surface proteins. Molecular and Biochemical Parasitology 110, 345-357. (Pubitemid 30845534)
    • (2000) Molecular and Biochemical Parasitology , vol.110 , Issue.2 , pp. 345-357
    • Wu, Y.1    El Fakhry, Y.2    Sereno, D.3    Tamar, S.4    Papadopoulou, B.5
  • 65
    • 0141888314 scopus 로고    scopus 로고
    • The major surface protease (MSP or GP63) of Leishmania sp. Biosynthesis, regulation of expression, and function
    • Yao, C., Donelson, J. E. and Wilson, M. E. (2003). The major surface protease (MSP or GP63) of Leishmania sp. Biosynthesis, regulation of expression, and function. Molecular and Biochemical Parasitology 132, 1-16.
    • (2003) Molecular and Biochemical Parasitology , vol.132 , pp. 1-16
    • Yao, C.1    Donelson, J.E.2    Wilson, M.E.3
  • 66
    • 2342461107 scopus 로고    scopus 로고
    • Immunization with the hybrid protein vaccine, consisting of Leishmania major cysteine proteinases Type I (CPB) and Type II (CPA), partially protects against leishmaniasis
    • DOI 10.1016/j.vaccine.2003.11.014, PII S0264410X03008053
    • Zadeh-Vakili, A., Taheri, T., Taslimi, Y., Doustdari, F., Salmanian, A. H. and Rafati, S. (2004). Immunization with the hybrid protein vaccine, consisting of Leishmania major cysteine proteinases Type I (CPB) and Type II (CPA), partially protects against leishmaniasis. Vaccine 22, 1930-1940. (Pubitemid 38581062)
    • (2004) Vaccine , vol.22 , Issue.15-16 , pp. 1930-1940
    • Zadeh-Vakili, A.1    Taheri, T.2    Taslimi, Y.3    Doustdari, F.4    Salmanian, A.-H.5    Rafati, S.6
  • 67
    • 0035117857 scopus 로고    scopus 로고
    • Characterization of the A2-A2rel gene cluster in Leishmania donovani: Involvement of A2 in visceralization during infection
    • Zhang, W. W. and Matlashewski, G. (2001). Characterization of the A2-A2rel gene cluster in Leishmania donovani: involvement of A2 in visceralization during infection. Molecular Microbiology 39, 935-948.
    • (2001) Molecular Microbiology , vol.39 , pp. 935-948
    • Zhang, W.W.1    Matlashewski, G.2
  • 68
    • 8544262185 scopus 로고    scopus 로고
    • In vivo selection for Leishmania donovani miniexon genes that increase virulence in Leishmania major
    • Zhang, W. W. and Matlashewski, G. (2004). In vivo selection for Leishmania donovani miniexon genes that increase virulence in Leishmania major. Molecular Microbiology 54, 1051-1062.
    • (2004) Molecular Microbiology , vol.54 , pp. 1051-1062
    • Zhang, W.W.1    Matlashewski, G.2
  • 69
    • 0030841734 scopus 로고    scopus 로고
    • Loss of virulence in Leishmania donovani deficient in an amastigote-specific protein, A2
    • Zhang, W. W. and Matlashewski, G. (1997). Loss of virulence in Leishmania donovani deficient in an amastigote-specific protein, A2. Proceedings of the National Academy of Sciences, USA 94, 8807-8811.
    • (1997) Proceedings of the National Academy of Sciences, USA , vol.94 , pp. 8807-8811
    • Zhang, W.W.1    Matlashewski, G.2
  • 70
    • 0041315545 scopus 로고    scopus 로고
    • Comparison of the A2 gene locus in Leishmania donovani and Leishmania major and its control over cutaneous infection
    • DOI 10.1074/jbc.M305030200
    • Zhang, W. W., Mendez, S., Ghosh, A., Myler, P., Ivens, A., Clos, J., Sacks, D. L. and Matlashewski, G. (2003). Comparison of the A2 gene locus in Leishmania donovani and Leishmania major and its control over cutaneous infection. Journal of Biological Chemistry 278, 35508-35515. (Pubitemid 37102322)
    • (2003) Journal of Biological Chemistry , vol.278 , Issue.37 , pp. 35508-35515
    • Zhang, W.-W.1    Mendez, S.2    Ghosh, A.3    Myler, P.4    Ivens, A.5    Clos, J.6    Sacks, D.L.7    Matlashewski, G.8


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