Targeted gene deletion in Leishmania major identifies leishmanolysin (GP63) as a virulence factor

Molecular and Biochemical Parasitology

Volumn 120, Issue 1, 2002, Pages 33-40

  Joshi, Phalgun B ^a   Kelly, Ben L ^a   Kamhawi, Shaden ^b   Sacks, David L ^b   McMaster, W Robert ^a  

^a VANCOUVER GENERAL HOSPITAL   (Canada)

^b NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES   (United States)

Author keywords

Complement; Leishmanolysin; Parasitic protozoan; Transgenic knockout

Indexed keywords

LEISHMANOLYSIN; METALLOPROTEINASE; UNCLASSIFIED DRUG; VIRULENCE FACTOR;

ARTICLE; CONTROLLED STUDY; DNA VECTOR; GENE DELETION; GENE EXPRESSION; GENE REPLACEMENT THERAPY; HOST PARASITE INTERACTION; LEISHMANIA MAJOR; MACROPHAGE; MOLECULAR CLONING; NONHUMAN; PARASITE VIRULENCE; PATHOGENESIS; PHENOTYPE; PRIORITY JOURNAL; PROMASTIGOTE; PROTEIN ANALYSIS; PROTEIN DEGRADATION; PSYCHODIDAE; SIGNAL TRANSDUCTION;

ANIMALIA; LEISHMANIA MAJOR; PHLEBOTOMINAE; PROTOZOA;

EID: 0036178528     PISSN: 01666851     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-6851(01)00432-7     Document Type: Article

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