Leishmania LPG3 encodes a GRP94 homolog required for phosphoglycan synthesis implicated in parasite virulence but not viability

EMBO Journal

Volumn 21, Issue 17, 2002, Pages 4458-4469

  Descoteaux, Albert ^a   Avila, Herbert A ^a   Zhang, Kai ^a   Turco, Salvatore J ^a   Beverley, Stephen M ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Glycoconjugate biosynthesis; GPI anchored molecules; Lipophosphoglycan; Parasite virulence; Trypanosomatid protozoan

Indexed keywords

CHAPERONE; GLYCAN DERIVATIVE; PHOSPHOGLYCAN; PROTEIN GRP 94; PROTEIN LPG 3; PROTOZOAL PROTEIN; UNCLASSIFIED DRUG;

ARTICLE; LEISHMANIA; LEISHMANIA DONOVANI; NONHUMAN; PARASITE VIRULENCE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN SYNTHESIS; REGULATORY MECHANISM; RNA ANALYSIS;

ALLELES; AMINO ACID SEQUENCE; ANIMALS; CARBOHYDRATE SEQUENCE; CARRIER PROTEINS; GENE EXPRESSION REGULATION; GENES, PROTOZOAN; GENETIC COMPLEMENTATION TEST; GLYCOSPHINGOLIPIDS; GLYCOSYLPHOSPHATIDYLINOSITOLS; HSP70 HEAT-SHOCK PROTEINS; HUMANS; LEISHMANIA DONOVANI; LEISHMANIA INFANTUM; MANNOSEPHOSPHATES; MEMBRANE PROTEINS; MOLECULAR CHAPERONES; MOLECULAR SEQUENCE DATA; N-ACETYLLACTOSAMINE SYNTHASE; PROTEIN BINDING; PROTOZOAN PROTEINS; RNA, MESSENGER; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; SPECIES SPECIFICITY; STRESS; VIRULENCE;

EUKARYOTA; LEISHMANIA DONOVANI; LEISHMANIA INFANTUM; MAMMALIA; PROTOZOA;

EID: 0037009446     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdf447     Document Type: Article

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