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Volumn 16, Issue 5, 2009, Pages 290-299

Glucocorticoid receptor in human respiratory epithelial cells

Author keywords

Airway inflammation; Airway respiratory diseases; Glucocorticoid; Glucocorticoid receptor isoforms; Respiratory airway epithelial cells

Indexed keywords

BUDESONIDE; GLUCOCORTICOID; GLUCOCORTICOID RECEPTOR ALPHA; GLUCOCORTICOID RECEPTOR BETA; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MESSENGER RNA; TRANSCRIPTION FACTOR AP 1;

EID: 67651089737     PISSN: 10217401     EISSN: None     Source Type: Journal    
DOI: 10.1159/000216187     Document Type: Review
Times cited : (23)

References (85)
  • 1
    • 26944454482 scopus 로고    scopus 로고
    • Glucocorticoids suppress inflammation but spare innate immune responses in airway epithelium
    • Schleimer RP: Glucocorticoids suppress inflammation but spare innate immune responses in airway epithelium. Proc Am Thorac Soc 2004;1:222-230.
    • (2004) Proc Am Thorac Soc , vol.1 , pp. 222-230
    • Schleimer, R.P.1
  • 2
    • 36749082528 scopus 로고    scopus 로고
    • Glucocorticoid actions on airway epithelial responses in immunity: Functional outcomes and molecular targets
    • Stellato C: Glucocorticoid actions on airway epithelial responses in immunity: functional outcomes and molecular targets. J Allergy Clin Immunol 2007;120: 1247-1263.
    • (2007) J Allergy Clin Immunol , vol.120 , pp. 1247-1263
    • Stellato, C.1
  • 4
    • 33746785057 scopus 로고    scopus 로고
    • Bousquet J, van Cauwenberge P, and members of the ARIA Science Committee: Phar-macologic and anti-IgE treatment of allergic rhinitis. ARIA update (in collaboration with GA2LEN). Allergy 2006;61: 1086-1096.
    • Bousquet J, van Cauwenberge P, and members of the ARIA Science Committee: Phar-macologic and anti-IgE treatment of allergic rhinitis. ARIA update (in collaboration with GA2LEN). Allergy 2006;61: 1086-1096.
  • 5
    • 34447542269 scopus 로고    scopus 로고
    • European position paper on rhinosinusitis and nasal polyps 2007
    • on behalf of the European Position Paper on Rhinosinusitis and Nasal Polyps Group
    • Fokkens W, Lund V, Mullol J, on behalf of the European Position Paper on Rhinosinusitis and Nasal Polyps Group: European position paper on rhinosinusitis and nasal polyps 2007. Rhinol Suppl 2007;20:1-136.
    • (2007) Rhinol Suppl , vol.20 , pp. 1-136
    • Fokkens, W.1    Lund, V.2    Mullol, J.3
  • 6
    • 34547863538 scopus 로고    scopus 로고
    • Molecular mechanisms of glucocorticoid action and selective glucocorticoid receptor agonists
    • Stahn C, Löwenberg M, Hommes DW, Buttgereit F: Molecular mechanisms of glucocorticoid action and selective glucocorticoid receptor agonists. Mol Cell Endocrinol 2007;275: 71-78.
    • (2007) Mol Cell Endocrinol , vol.275 , pp. 71-78
    • Stahn, C.1    Löwenberg, M.2    Hommes, D.W.3    Buttgereit, F.4
  • 7
    • 26844433194 scopus 로고    scopus 로고
    • Anti-inflammatory action of glucocorticoids - new mechanisms for old drugs
    • Rhen T, Cidlowski JA: Anti-inflammatory action of glucocorticoids - new mechanisms for old drugs. N Engl J Med 2005;353:1711-1723.
    • (2005) N Engl J Med , vol.353 , pp. 1711-1723
    • Rhen, T.1    Cidlowski, J.A.2
  • 8
  • 9
    • 33745090483 scopus 로고    scopus 로고
    • Glucocorticoid receptor isoforms generate transcription specificity
    • Lu NZ, Cidlowski JA: Glucocorticoid receptor isoforms generate transcription specificity. Trends Cell Biol 2006;16:301-307.
    • (2006) Trends Cell Biol , vol.16 , pp. 301-307
    • Lu, N.Z.1    Cidlowski, J.A.2
  • 10
    • 33751000477 scopus 로고    scopus 로고
    • Multiple glucocorticoid receptor isoforms and mechanisms of post-translational modification
    • Duma D, Jewell CM, Cidlowski JA: Multiple glucocorticoid receptor isoforms and mechanisms of post-translational modification. J Steroid Biochem Mol Biol 2006;102:11-21.
    • (2006) J Steroid Biochem Mol Biol , vol.102 , pp. 11-21
    • Duma, D.1    Jewell, C.M.2    Cidlowski, J.A.3
  • 11
    • 34248575033 scopus 로고    scopus 로고
    • Alpha- and beta-glucocorticoid receptors: Relevance in airway diseases
    • Pujols L, Mullol J, Picado C: Alpha- and beta-glucocorticoid receptors: relevance in airway diseases. Curr Allergy Asthma Rep 2007;7: 93-99.
    • (2007) Curr Allergy Asthma Rep , vol.7 , pp. 93-99
    • Pujols, L.1    Mullol, J.2    Picado, C.3
  • 12
    • 34547884315 scopus 로고    scopus 로고
    • Crosstalk between the glucocorticoid receptor and other transcription factors: Molecular aspects
    • Kassel O, Herrlich P: Crosstalk between the glucocorticoid receptor and other transcription factors: molecular aspects. Mol Cell Endocrinol 2007;275:13-29.
    • (2007) Mol Cell Endocrinol , vol.275 , pp. 13-29
    • Kassel, O.1    Herrlich, P.2
  • 14
    • 34547883918 scopus 로고    scopus 로고
    • Anti-inflammatory functions of glucocorticoid-induced genes
    • Clark AR: Anti-inflammatory functions of glucocorticoid-induced genes. Mol Cell Endocrinol 2007;275: 79-97.
    • (2007) Mol Cell Endocrinol , vol.275 , pp. 79-97
    • Clark, A.R.1
  • 15
    • 33751064334 scopus 로고    scopus 로고
    • Tissue-specific glucocorticoid receptor expression, a role for alternative first exon usage?
    • Turner JD, Schote AB, Macedo JA, Pelascini LPL, Muller CP: Tissue-specific glucocorticoid receptor expression, a role for alternative first exon usage? Biochem Pharmacol 2006;72: 1529-1537.
    • (2006) Biochem Pharmacol , vol.72 , pp. 1529-1537
    • Turner, J.D.1    Schote, A.B.2    Macedo, J.A.3    Pelascini, L.P.L.4    Muller, C.P.5
  • 16
    • 0029993518 scopus 로고    scopus 로고
    • The human glucocorticoid receptor beta isoform. Expression, biochemical properties, and putative function
    • Oakley RH, Sar M, Cidlowski JA: The human glucocorticoid receptor beta isoform. Expression, biochemical properties, and putative function. J Biol Chem 1996;271:9550-9559.
    • (1996) J Biol Chem , vol.271 , pp. 9550-9559
    • Oakley, R.H.1    Sar, M.2    Cidlowski, J.A.3
  • 18
    • 20844437424 scopus 로고    scopus 로고
    • Translational regulatory mechanisms generate N-terminal glucocorticoid receptor isoforms with unique transcriptional target genes
    • Lu NZ, Cidlowski JA: Translational regulatory mechanisms generate N-terminal glucocorticoid receptor isoforms with unique transcriptional target genes. Mol Cell 2005;18: 331-342.
    • (2005) Mol Cell , vol.18 , pp. 331-342
    • Lu, N.Z.1    Cidlowski, J.A.2
  • 19
    • 35148835555 scopus 로고    scopus 로고
    • Selective regulation of bone cell apoptosis by translational isoforms of the glucocorticoid receptor
    • Lu NZ, Collins JB, Grissom SF, Cidlowski JA: Selective regulation of bone cell apoptosis by translational isoforms of the glucocorticoid receptor. Mol Cell Biol 2007;27: 7143-7160.
    • (2007) Mol Cell Biol , vol.27 , pp. 7143-7160
    • Lu, N.Z.1    Collins, J.B.2    Grissom, S.F.3    Cidlowski, J.A.4
  • 20
    • 31344446119 scopus 로고    scopus 로고
    • Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-κB suppression
    • Ito K, Yamamura S, Essilfie-Quaye S, Cosio B, Ito M, Barnes PJ, Adcodk IM: Histone deacetylase 2-mediated deacetylation of the glucocorticoid receptor enables NF-κB suppression. J Exp Med 2006;203: 7-13.
    • (2006) J Exp Med , vol.203 , pp. 7-13
    • Ito, K.1    Yamamura, S.2    Essilfie-Quaye, S.3    Cosio, B.4    Ito, M.5    Barnes, P.J.6    Adcodk, I.M.7
  • 21
    • 34548856201 scopus 로고    scopus 로고
    • Impact of protein acetylation in inflammatory lung diseases
    • Ito K, Charron CE, Adcodk IM: Impact of protein acetylation in inflammatory lung diseases. Pharmacol Ther 2007;116: 249-265.
    • (2007) Pharmacol Ther , vol.116 , pp. 249-265
    • Ito, K.1    Charron, C.E.2    Adcodk, I.M.3
  • 22
    • 33845382332 scopus 로고    scopus 로고
    • Importin-13 regulates nuclear import of the glucocorticoid receptor in airway epithelial cells
    • Tao T, Lan J, Lukacs GL, HachéRJ, Kaplan F: Importin-13 regulates nuclear import of the glucocorticoid receptor in airway epithelial cells. Am J Respir Cell Mol Biol 2006;35: 668-680.
    • (2006) Am J Respir Cell Mol Biol , vol.35 , pp. 668-680
    • Tao, T.1    Lan, J.2    Lukacs, G.L.3    Haché, R.J.4    Kaplan, F.5
  • 23
    • 4644235617 scopus 로고    scopus 로고
    • Glucocorticoid receptors in human airways
    • Pujols L, Mullol J, Torrego A, Picado C: Glucocorticoid receptors in human airways. Allergy 2004;59:1042-1052.
    • (2004) Allergy , vol.59 , pp. 1042-1052
    • Pujols, L.1    Mullol, J.2    Torrego, A.3    Picado, C.4
  • 24
    • 17844365062 scopus 로고    scopus 로고
    • Linking the ubiquitin-proteasome pathway to chromatin remodeling/modification by nuclear receptors
    • Kinyamu HK, Chen J, Archer TK: Linking the ubiquitin-proteasome pathway to chromatin remodeling/modification by nuclear receptors. J Mol Endocrinol 2005;34:281-297.
    • (2005) J Mol Endocrinol , vol.34 , pp. 281-297
    • Kinyamu, H.K.1    Chen, J.2    Archer, T.K.3
  • 26
    • 33846867493 scopus 로고    scopus 로고
    • Glucocorticoids in innate immunity: More transactivation than transrepres-sion
    • Perreti M: Glucocorticoids in innate immunity: more transactivation than transrepres-sion. Blood 2007;109:852-853.
    • (2007) Blood , vol.109 , pp. 852-853
    • Perreti, M.1
  • 27
    • 33845945174 scopus 로고    scopus 로고
    • The antiinflammatory effect of glucocorticoids is mediated by glucocorticoid-induced leucine zipper in epithelial cells
    • Eddleston J, Herschbach J, Wagelie-Steffen AL, Christiansen SC, Zuraw BL: The antiinflammatory effect of glucocorticoids is mediated by glucocorticoid-induced leucine zipper in epithelial cells. J Allergy Clin Immunol 2007;119:115-122.
    • (2007) J Allergy Clin Immunol , vol.119 , pp. 115-122
    • Eddleston, J.1    Herschbach, J.2    Wagelie-Steffen, A.L.3    Christiansen, S.C.4    Zuraw, B.L.5
  • 29
    • 33845218654 scopus 로고    scopus 로고
    • Glucocorticoids regulate tristetraprolin synthesis and post-transcriptionally regulate tumor necrosis factor α inflammatory signaling
    • Smoak K, Cidlowski JA: Glucocorticoids regulate tristetraprolin synthesis and post-transcriptionally regulate tumor necrosis factor α inflammatory signaling. Mol Cell Biol 2006;26: 9126-9135.
    • (2006) Mol Cell Biol , vol.26 , pp. 9126-9135
    • Smoak, K.1    Cidlowski, J.A.2
  • 32
    • 33751543436 scopus 로고    scopus 로고
    • Rapid glucocorticoid signaling via membrane-associated receptors
    • Tasker JG, Di S, Malcher-Lopes R: Rapid glucocorticoid signaling via membrane-associated receptors. Endocrinology 2006;147: 5549-5556.
    • (2006) Endocrinology , vol.147 , pp. 5549-5556
    • Tasker, J.G.1    Di, S.2    Malcher-Lopes, R.3
  • 33
    • 33645394365 scopus 로고    scopus 로고
    • Rapid anti-secretory effects of glucocorticoids in human airway epithelium
    • Urbach V, Verriere V, Grumbach Y, Bous-quet J, Harvey BJ: Rapid anti-secretory effects of glucocorticoids in human airway epithelium. Steroids 2006;71: 323-328.
    • (2006) Steroids , vol.71 , pp. 323-328
    • Urbach, V.1    Verriere, V.2    Grumbach, Y.3    Bous-quet, J.4    Harvey, B.J.5
  • 34
    • 0030691015 scopus 로고    scopus 로고
    • Evidence that the β-isoform of the human glucocorticoid receptor does not act as a physiologically significant repressor
    • Hecht K, Carlstedt-Duke J, Stierna P, Gus-tafsson JÅ, Brönnegård M, Wikström AC: Evidence that the β-isoform of the human glucocorticoid receptor does not act as a physiologically significant repressor. J Biol Chem 1997;272:26659-26664.
    • (1997) J Biol Chem , vol.272 , pp. 26659-26664
    • Hecht, K.1    Carlstedt-Duke, J.2    Stierna, P.3    Gus-tafsson, J.Å.4    Brönnegård, M.5    Wikström, A.C.6
  • 36
    • 0032701608 scopus 로고    scopus 로고
    • Interaction of glucocorticoid receptor isoform with transcription factors AP-1 and NF- κB: Lack of effect of glucocorticoid receptor β
    • Brogan IJ, Murray IA, Cerillo G, Needham M, White A, Davis JRE: Interaction of glucocorticoid receptor isoform with transcription factors AP-1 and NF- κB: lack of effect of glucocorticoid receptor β. Mol Cell Endocrinol 1999;157: 95-104.
    • (1999) Mol Cell Endocrinol , vol.157 , pp. 95-104
    • Brogan, I.J.1    Murray, I.A.2    Cerillo, G.3    Needham, M.4    White, A.5    Davis, J.R.E.6
  • 37
    • 0033600936 scopus 로고    scopus 로고
    • The dominant negative activity of the human glucocorticoid receptor β isoform. Specificity and mechanisms of action
    • Oakley RH, Jewell CM, Yudt MR, Bofetiado DM, Cidlowski JA: The dominant negative activity of the human glucocorticoid receptor β isoform. Specificity and mechanisms of action. J Biol Chem 1999;274:27857-27866.
    • (1999) J Biol Chem , vol.274 , pp. 27857-27866
    • Oakley, R.H.1    Jewell, C.M.2    Yudt, M.R.3    Bofetiado, D.M.4    Cidlowski, J.A.5
  • 38
    • 0029056558 scopus 로고
    • Glucocorticoid receptor p, a potential endogenous inhibitor of glucocorticoid action in humans
    • Bamberger CM, Bamberger AM, de Castro M, Chrousos GP: Glucocorticoid receptor p, a potential endogenous inhibitor of glucocorticoid action in humans. J Clin Invest 1995;95: 2435-2441.
    • (1995) J Clin Invest , vol.95 , pp. 2435-2441
    • Bamberger, C.M.1    Bamberger, A.M.2    de Castro, M.3    Chrousos, G.P.4
  • 39
    • 0036013805 scopus 로고    scopus 로고
    • Over-expression of the human glucocorticoid receptor α and β isoforms inhibits AP-1 and NF-κB activities hormone independently
    • Gougat C, Jaffuel D, Gagliardo R, Henriquet C, Bousquet J, Demoly P, Mathieu M: Over-expression of the human glucocorticoid receptor α and β isoforms inhibits AP-1 and NF-κB activities hormone independently. J Mol Med 2002;80:309-318.
    • (2002) J Mol Med , vol.80 , pp. 309-318
    • Gougat, C.1    Jaffuel, D.2    Gagliardo, R.3    Henriquet, C.4    Bousquet, J.5    Demoly, P.6    Mathieu, M.7
  • 40
    • 0033587516 scopus 로고    scopus 로고
    • Natural variants of the β isoform of the human glucocorticoid receptor do not alter sensitivity to glucocorticoids
    • De Lange, Koper JW, Brinkmann AO, de Jong FH, Lamberts SWJ: Natural variants of the β isoform of the human glucocorticoid receptor do not alter sensitivity to glucocorticoids. Mol Cell Endocrinol 1999;153:163-168.
    • (1999) Mol Cell Endocrinol , vol.153 , pp. 163-168
    • Lange, D.1    Koper, J.W.2    Brinkmann, A.O.3    de Jong, F.H.4    Lamberts, S.W.J.5
  • 41
    • 0035809314 scopus 로고    scopus 로고
    • High constitutive glucocorticoid receptor β in human neutrophils enables them to reduce their spontaneous rate of cell death in response to corticosteroids
    • Strickland I, Kisich K, Hauk PJ, Vottero A, Chrousos GP, Klemm DJ, Leung DY: High constitutive glucocorticoid receptor β in human neutrophils enables them to reduce their spontaneous rate of cell death in response to corticosteroids. J Exp Med 2001;193:585-594.
    • (2001) J Exp Med , vol.193 , pp. 585-594
    • Strickland, I.1    Kisich, K.2    Hauk, P.J.3    Vottero, A.4    Chrousos, G.P.5    Klemm, D.J.6    Leung, D.Y.7
  • 43
    • 0037979126 scopus 로고    scopus 로고
    • Molecular origins for the dominant negative function of human glucocorticoid receptor β
    • Yudt MR, Jewell CM, Bienstock RJ, Cidlowski JA: Molecular origins for the dominant negative function of human glucocorticoid receptor β. Mol Cell Biol 2003;23: 4319-4330.
    • (2003) Mol Cell Biol , vol.23 , pp. 4319-4330
    • Yudt, M.R.1    Jewell, C.M.2    Bienstock, R.J.3    Cidlowski, J.A.4
  • 44
    • 11244329291 scopus 로고    scopus 로고
    • The human glucocorticoid receptor (hGR)-β isoform suppresses the transcriptional activity of hGR-α by interfering with formation of active coactivator complexes
    • Charmandari E, Chrousos GP, Ichijo T, Bhattacharyya N, Vottero A, Souvatzoglou E, Kino T: The human glucocorticoid receptor (hGR)-β isoform suppresses the transcriptional activity of hGR-α by interfering with formation of active coactivator complexes. Mol Endocrinol 2005;19:52-64.
    • (2005) Mol Endocrinol , vol.19 , pp. 52-64
    • Charmandari, E.1    Chrousos, G.P.2    Ichijo, T.3    Bhattacharyya, N.4    Vottero, A.5    Souvatzoglou, E.6    Kino, T.7
  • 45
  • 49
    • 0032898142 scopus 로고    scopus 로고
    • Pharmacological characterization of glucocorticoid receptors in primary human bronchial epithelial cells
    • LeVan TD, Babin EA, Yamamura HI, Bloom JW: Pharmacological characterization of glucocorticoid receptors in primary human bronchial epithelial cells. Biochem Pharmacol 1999;57: 1003-1009.
    • (1999) Biochem Pharmacol , vol.57 , pp. 1003-1009
    • LeVan, T.D.1    Babin, E.A.2    Yamamura, H.I.3    Bloom, J.W.4
  • 52
    • 0035132054 scopus 로고    scopus 로고
    • Expression of the human glucocorticoid receptor α and β isoforms in human respiratory epithelial cells and their regulation by dexamethasone
    • Pujols L, Mullol J, Pérez M, Roca-Ferrer J, Juan M, Xaubet A, Cidlowski JA, Picado C: Expression of the human glucocorticoid receptor α and β isoforms in human respiratory epithelial cells and their regulation by dexamethasone. Am J Respir Cell Mol Biol 2001;24: 49-57.
    • (2001) Am J Respir Cell Mol Biol , vol.24 , pp. 49-57
    • Pujols, L.1    Mullol, J.2    Pérez, M.3    Roca-Ferrer, J.4    Juan, M.5    Xaubet, A.6    Cidlowski, J.A.7    Picado, C.8
  • 54
    • 0036142243 scopus 로고    scopus 로고
    • Expression of glucocorticoid receptors and cyclooxygenase-2 in nasal polyps from nonallergic patients
    • Yun CB, Lee BH, Jang TJ: Expression of glucocorticoid receptors and cyclooxygenase-2 in nasal polyps from nonallergic patients. Ann Otol Rhinol Laryngol 2002;111: 61-67.
    • (2002) Ann Otol Rhinol Laryngol , vol.111 , pp. 61-67
    • Yun, C.B.1    Lee, B.H.2    Jang, T.J.3
  • 56
    • 0030894724 scopus 로고    scopus 로고
    • In vitro and in vivo modulation of α- and β-glucocorticoid-receptor mRNA in human bronchial epithelium
    • Korn SH, Wouters EF, Wesseling G, Arends JW, Thunnissen FB: In vitro and in vivo modulation of α- and β-glucocorticoid-receptor mRNA in human bronchial epithelium. Am J Respir Crit Care Med 1997;155: 1117-1122.
    • (1997) Am J Respir Crit Care Med , vol.155 , pp. 1117-1122
    • Korn, S.H.1    Wouters, E.F.2    Wesseling, G.3    Arends, J.W.4    Thunnissen, F.B.5
  • 57
    • 0030048554 scopus 로고    scopus 로고
    • Regulation of glucocorticoid receptor mRNA in nasal mucosa by local administration of fluticasone and budesonide
    • Knutsson PU, Brönnegård M, Marcus C, Stierna P: Regulation of glucocorticoid receptor mRNA in nasal mucosa by local administration of fluticasone and budesonide. J Allergy Clin Immunol 1996;97: 655-661.
    • (1996) J Allergy Clin Immunol , vol.97 , pp. 655-661
    • Knutsson, P.U.1    Brönnegård, M.2    Marcus, C.3    Stierna, P.4
  • 58
    • 0035090577 scopus 로고    scopus 로고
    • Effects of topical budesonide treatment on glucocorticoid receptor mRNA downregulation and cytokine patterns in nasal polyps
    • Henriksson G, Norlander T, Forsgren J, Stierna P: Effects of topical budesonide treatment on glucocorticoid receptor mRNA downregulation and cytokine patterns in nasal polyps. Am J Rhinol 2001;15: 1-8.
    • (2001) Am J Rhinol , vol.15 , pp. 1-8
    • Henriksson, G.1    Norlander, T.2    Forsgren, J.3    Stierna, P.4
  • 60
    • 0028079557 scopus 로고
    • Steroid-resistant asthma. Cellular mechanisms contributing to inadequate response to glucocorticoid therapy
    • Sher ER, Leung DY, Surs W, Kam JC, Zieg G, Kamada AK, Szefler SJ: Steroid-resistant asthma. Cellular mechanisms contributing to inadequate response to glucocorticoid therapy. J Clin Invest 1994;93:33-39.
    • (1994) J Clin Invest , vol.93 , pp. 33-39
    • Sher, E.R.1    Leung, D.Y.2    Surs, W.3    Kam, J.C.4    Zieg, G.5    Kamada, A.K.6    Szefler, S.J.7
  • 61
    • 0036231010 scopus 로고    scopus 로고
    • p38 Mitogen-ac-tivated protein kinase-induced glucocorticoid receptor phosphorylation reduces its activity: Role in steroid-insensitive asthma
    • Irusen E, Matthews JG, Takahashi A, Barnes PJ, Chung KF, Adcock IM: p38 Mitogen-ac-tivated protein kinase-induced glucocorticoid receptor phosphorylation reduces its activity: role in steroid-insensitive asthma. J Allergy Clin Immunol 2002;109:649-657.
    • (2002) J Allergy Clin Immunol , vol.109 , pp. 649-657
    • Irusen, E.1    Matthews, J.G.2    Takahashi, A.3    Barnes, P.J.4    Chung, K.F.5    Adcock, I.M.6
  • 62
    • 3042788350 scopus 로고    scopus 로고
    • Modulation of glucocorticoid receptor function via phosphorylation
    • Ismaili N, Garabedian MJ: Modulation of glucocorticoid receptor function via phosphorylation. Ann NY Acad Sci 2004;1024: 86-101.
    • (2004) Ann NY Acad Sci , vol.1024 , pp. 86-101
    • Ismaili, N.1    Garabedian, M.J.2
  • 63
    • 34948900221 scopus 로고    scopus 로고
    • Steroid receptor phosphorylation: A key modulator of multiple receptor functions
    • Weigel NL, Moore NL: Steroid receptor phosphorylation: a key modulator of multiple receptor functions. Mol Endocrinol 2007;21:2311-2319.
    • (2007) Mol Endocrinol , vol.21 , pp. 2311-2319
    • Weigel, N.L.1    Moore, N.L.2
  • 64
    • 48249157970 scopus 로고    scopus 로고
    • Chen W, Dang T, Blind RD, Wang Z, Cavasotto CN, Hittelman AB, Rogatsky I, Logan SK, Garabedian MJ: Glucocorticoid receptor phosphorylation differentially affects target gene expression. Mol Endocrinol 2008;22: 1754-1766.
    • Chen W, Dang T, Blind RD, Wang Z, Cavasotto CN, Hittelman AB, Rogatsky I, Logan SK, Garabedian MJ: Glucocorticoid receptor phosphorylation differentially affects target gene expression. Mol Endocrinol 2008;22: 1754-1766.
  • 65
    • 31044434618 scopus 로고    scopus 로고
    • CD38 expression is insensitive to steroid action in cells treated with tumor necrosis factor-α and interferon-γ by a mechanism involving the upregulation of the glucocorticoid receptor β isoform
    • Tliba O, Cidlowski JA, Amrani Y: CD38 expression is insensitive to steroid action in cells treated with tumor necrosis factor-α and interferon-γ by a mechanism involving the upregulation of the glucocorticoid receptor β isoform. Mol Pharmacol 2006;69:588-596.
    • (2006) Mol Pharmacol , vol.69 , pp. 588-596
    • Tliba, O.1    Cidlowski, J.A.2    Amrani, Y.3
  • 66
    • 41449101856 scopus 로고    scopus 로고
    • Cytokines induce an early steroid resistance in airway smooth muscle cells: Novel role of interferon regulatory factor-1
    • Tliba O, Damera G, Banerjee A, Gu S, Baidouri H, Keslacy S, Amrani Y: Cytokines induce an early steroid resistance in airway smooth muscle cells: novel role of interferon regulatory factor-1. Am J Respir Cell Mol Biol 2008;38:463-472.
    • (2008) Am J Respir Cell Mol Biol , vol.38 , pp. 463-472
    • Tliba, O.1    Damera, G.2    Banerjee, A.3    Gu, S.4    Baidouri, H.5    Keslacy, S.6    Amrani, Y.7
  • 67
    • 0035521148 scopus 로고    scopus 로고
    • Epithelial cells infected with respiratory syncytial virus are resistant to the anti-inflammatory effects of hydrocortisone
    • Bonville CA, Mehta PA, Krilov LR, Rosenberg HF, Domachowske JB: Epithelial cells infected with respiratory syncytial virus are resistant to the anti-inflammatory effects of hydrocortisone. Cell Immunol 2001;213: 134-140.
    • (2001) Cell Immunol , vol.213 , pp. 134-140
    • Bonville, C.A.1    Mehta, P.A.2    Krilov, L.R.3    Rosenberg, H.F.4    Domachowske, J.B.5
  • 69
    • 51249109929 scopus 로고    scopus 로고
    • Relative corticosteroid insensitivity of alveolar macrophages in severe asthma compared with non-severe asthma
    • Bhavsar P, Hew M, Khorasani N, Torrego A, Barnes PJ, Adcock I, Chung KF: Relative corticosteroid insensitivity of alveolar macrophages in severe asthma compared with non-severe asthma. Thorax 2008;63: 784-790.
    • (2008) Thorax , vol.63 , pp. 784-790
    • Bhavsar, P.1    Hew, M.2    Khorasani, N.3    Torrego, A.4    Barnes, P.J.5    Adcock, I.6    Chung, K.F.7
  • 72
    • 0037244071 scopus 로고    scopus 로고
    • Expression of the glucocorticoid receptor α and β isoforms in human nasal mucosa and polyp epithelial cells
    • Pujols L, Mullol J, Benítez P, Torrego A, Xaubet A, de Haro J, Picado C: Expression of the glucocorticoid receptor α and β isoforms in human nasal mucosa and polyp epithelial cells. Respir Med 2003;97: 90-96.
    • (2003) Respir Med , vol.97 , pp. 90-96
    • Pujols, L.1    Mullol, J.2    Benítez, P.3    Torrego, A.4    Xaubet, A.5    de Haro, J.6    Picado, C.7
  • 75
    • 33746423134 scopus 로고    scopus 로고
    • Divergent expression and function of glucocorticoid receptor β in human monocytes and T cells
    • Li LB, Leung DY, Hall CF, Goleva E: Divergent expression and function of glucocorticoid receptor β in human monocytes and T cells. J Leukoc Biol 2006;79:818-827.
    • (2006) J Leukoc Biol , vol.79 , pp. 818-827
    • Li, L.B.1    Leung, D.Y.2    Hall, C.F.3    Goleva, E.4
  • 76
    • 0030774245 scopus 로고    scopus 로고
    • Expression and subcellular distribution of the β-isoform of the human glucocorticoid receptor
    • Oakley RH, Webster JC, Sar M, Parker CR Cidlowski JA: Expression and subcellular distribution of the β-isoform of the human glucocorticoid receptor. Endocrinology 1997;138: 5028-5038.
    • (1997) Endocrinology , vol.138 , pp. 5028-5038
    • Oakley, R.H.1    Webster, J.C.2    Sar, M.3    Parker, C.R.4    Cidlowski, J.A.5
  • 77
    • 0004815929 scopus 로고    scopus 로고
    • Glucocorticoid resistance in asthma is associated with elevated in vivo expression of the glucocorticoid receptor β-isoform
    • Sousa AR, Lane SJ, Cidlowski JA, Staynov DZ, Lee TH: Glucocorticoid resistance in asthma is associated with elevated in vivo expression of the glucocorticoid receptor β-isoform. J Allergy Clin Immunol 2000;105: 943-950.
    • (2000) J Allergy Clin Immunol , vol.105 , pp. 943-950
    • Sousa, A.R.1    Lane, S.J.2    Cidlowski, J.A.3    Staynov, D.Z.4    Lee, T.H.5
  • 78
    • 0034048372 scopus 로고    scopus 로고
    • Induction of corticosteroid insensitivity in human PBMCs by microbial superantigens
    • Hauk PJ, Hamid QA, Chrousos GP, Leung DY: Induction of corticosteroid insensitivity in human PBMCs by microbial superantigens. J Allergy Clin Immunol 2000;105: 782-787.
    • (2000) J Allergy Clin Immunol , vol.105 , pp. 782-787
    • Hauk, P.J.1    Hamid, Q.A.2    Chrousos, G.P.3    Leung, D.Y.4
  • 82
    • 0034742656 scopus 로고    scopus 로고
    • GR β expression in nasal polyps inflammatory cells and its relationship to the anti-inflammatory effects of intranasal fluticasone
    • Hamilos DL, Leung DY, Muro S, Kahn AM, Hamilos SS, Thawley SE, Hamid QA: GR β expression in nasal polyps inflammatory cells and its relationship to the anti-inflammatory effects of intranasal fluticasone. J Allergy Clin Immunol 2001;108:59-68.
    • (2001) J Allergy Clin Immunol , vol.108 , pp. 59-68
    • Hamilos, D.L.1    Leung, D.Y.2    Muro, S.3    Kahn, A.M.4    Hamilos, S.S.5    Thawley, S.E.6    Hamid, Q.A.7
  • 84
    • 0035810930 scopus 로고    scopus 로고
    • Proinflammatory cytokines regulate human glucocorticoid receptor gene expression and lead to the accumulation of the dominant negative β isoform: A mechanism for the generation of glucocorticoid resistance
    • Webster JC, Oakley RH, Jewell CM, Cidlowski JA: Proinflammatory cytokines regulate human glucocorticoid receptor gene expression and lead to the accumulation of the dominant negative β isoform: a mechanism for the generation of glucocorticoid resistance. PNAS 2001;98:6865-6870.
    • (2001) PNAS , vol.98 , pp. 6865-6870
    • Webster, J.C.1    Oakley, R.H.2    Jewell, C.M.3    Cidlowski, J.A.4


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