메뉴 건너뛰기




Volumn 11, Issue 2, 2009, Pages 201-212

The effects of cardiovascular risk factors on cognitive compromise

Author keywords

Alzheimer's disease; Cholesterol; Cognitive decline; Dementia; Diabetes; Hypertension; Inflammation; Mild cognitive impairment

Indexed keywords

ANTIHYPERTENSIVE AGENT; C REACTIVE PROTEIN; CHOLESTEROL; HYDROXYMETHYLGLUTARYL COENZYME A REDUCTASE INHIBITOR; INTERLEUKIN 6; NONSTEROID ANTIINFLAMMATORY AGENT; ROSIGLITAZONE;

EID: 67650802371     PISSN: 12948322     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (86)

References (163)
  • 2
    • 0037202852 scopus 로고    scopus 로고
    • The dementias
    • Ritchie K, Lovestone S. The dementias. Lancet. 2002;360:1759-1766.
    • (2002) Lancet , vol.360 , pp. 1759-1766
    • Ritchie, K.1    Lovestone, S.2
  • 3
    • 0028386613 scopus 로고
    • Frequency, distribution, and risk factors for Alzheimer's disease
    • Rocca WA. Frequency, distribution, and risk factors for Alzheimer's disease. Nurs Clin North Am. 1994;29:101-111.
    • (1994) Nurs Clin North Am , vol.29 , pp. 101-111
    • Rocca, W.A.1
  • 4
    • 4544359508 scopus 로고    scopus 로고
    • Cardiovascular risk factors and Alzheimer's disease
    • Luchsinger JA, Mayeux R. Cardiovascular risk factors and Alzheimer's disease. Curr Atheroscler Rep. 2004;6:261-266. (Pubitemid 39359464)
    • (2004) Current Atherosclerosis Reports , vol.6 , Issue.4 , pp. 261-266
    • Luchsinger, J.A.1    Mayeux, R.2
  • 6
    • 28444436918 scopus 로고    scopus 로고
    • Challenges in the epidemiological investigation of the relationships between physical activity, obesity, diabetes, dementia and depression
    • DOI 10.1016/j.neurobiolaging.2005.09.030, PII S0197458005003064
    • Brayne C, Gao L, Matthews F. Challenges in the epidemiological investigation of the relationships between physical activity, obesity, diabetes, dementia and depression. Neurobiol Aging. 2005;26(suppl 1):6-10. (Pubitemid 41739417)
    • (2005) Neurobiology of Aging , vol.26 , Issue.SUPPL.
    • Brayne, C.1    Gao, L.2    Matthews, F.3
  • 7
    • 4143119982 scopus 로고    scopus 로고
    • Diabetes, impaired fasting glucose, and development of cognitive impairment in older women
    • Yaffe K, Blackwell T, Kanaya AM, Davidowitz N, Barrett-Connor E, Krueger K. Diabetes, impaired fasting glucose, and development of cognitive impairment in older women. Neurology. 2004;63:658-663. (Pubitemid 39100821)
    • (2004) Neurology , vol.63 , Issue.4 , pp. 658-663
    • Yaffe, K.1    Blackwell, T.2    Kanaya, A.M.3    Davidowitz, N.4    Barrett-Connor, E.5    Krueger, K.6
  • 10
    • 12744273863 scopus 로고    scopus 로고
    • Midlife cardiovascular risk factors and risk of dementia in late life
    • Whitmer RA, Sidney S, Selby J, Johnston SC, Yaffe K. Midlife cardiovascular risk factors and risk of dementia in late life. Neurology. 2005;64:277-281.
    • (2005) Neurology , vol.64 , pp. 277-281
    • Whitmer, R.A.1    Sidney, S.2    Selby, J.3    Johnston, S.C.4    Yaffe, K.5
  • 11
    • 5344237420 scopus 로고    scopus 로고
    • Diabetes mellitus and risk of dementia in the Kungsholmen project: A 6-year follow-up study
    • Xu WL, Qiu CX, Wahlin A, Winblad B, Fratiglioni L. Diabetes mellitus and risk of dementia in the Kungsholmen project: a 6-year follow-up study. Neurology. 2004;63:1181-1186. (Pubitemid 39350014)
    • (2004) Neurology , vol.63 , Issue.7 , pp. 1181-1186
    • Xu, W.L.1    Qiu, C.X.2    Wahlin, A.3    Winblad, B.4    Fratiglioni, L.5
  • 12
    • 0036227542 scopus 로고    scopus 로고
    • Type 2 diabetes, APOE gene, and the risk for dementia and related pathologies: The Honolulu-Asia Aging Study
    • Peila R, Rodriguez BL, Launer LJ. Type 2 diabetes, APOE gene, and the risk for dementia and related pathologies: The Honolulu-Asia Aging Study. Diabetes. 2002;51:1256-1262.
    • (2002) Diabetes , vol.51 , pp. 1256-1262
    • Peila, R.1    Rodriguez, B.L.2    Launer, L.J.3
  • 14
    • 0036973393 scopus 로고    scopus 로고
    • Diabetes mellitus and the risk of dementia, Alzheimer's disease and vascular cognitive impairment in the Canadian Study of Health and Aging
    • MacKnight C, Rockwood K, Awalt E, McDowell I. Diabetes mellitus and the risk of dementia, Alzheimer's disease and vascular cognitive impairment in the Canadian Study of Health and Aging. Dement Geriatr Cogn Disord. 2002;14:77-83.
    • (2002) Dement Geriatr Cogn Disord , vol.14 , pp. 77-83
    • MacKnight, C.1    Rockwood, K.2    Awalt, E.3    McDowell, I.4
  • 15
    • 0036759508 scopus 로고    scopus 로고
    • Diabetes mellitus is a risk factor for vascular dementia, but not for Alzheimer's disease: A population-based study of the oldest old
    • DOI 10.1017/S104161020200844X
    • Hassing LB, Johansson B, Nilsson SE, et al. Diabetes mellitus is a risk factor for vascular dementia, but not for Alzheimer's disease: a population-based study of the oldest old. Int Psychogeriatr. 2002;14:239-248. (Pubitemid 35375539)
    • (2002) International Psychogeriatrics , vol.14 , Issue.3 , pp. 239-248
    • Hassing, L.B.1    Johansson, B.2    Nilsson, S.E.3    Berg, S.4    Pedersen, N.L.5    Gatz, M.6    McClearn, G.7
  • 16
    • 0035479310 scopus 로고    scopus 로고
    • Diabetes mellitus and risk of Alzheimer's disease and dementia with stroke in a multiethnic cohort
    • DOI 10.1093/aje/154.7.635
    • Luchsinger JA, Tang MX, Stern Y, Shea S, Mayeux R. Diabetes mellitus and risk of Alzheimer's disease and dementia with stroke in a multiethnic cohort. Am J Epidemiol. 2001 1;154:635-641. (Pubitemid 32888781)
    • (2001) American Journal of Epidemiology , vol.154 , Issue.7 , pp. 635-641
    • Luchsinger, J.A.1    Tang, M.-X.2    Stern, Y.3    Shea, S.4    Mayeux, R.5
  • 18
    • 0034707612 scopus 로고    scopus 로고
    • Is diabetes associated with cognitive impairment and cognitive decline among older women? Study of Osteoporotic Fractures Research Group
    • Gregg EW, Yaffe K, Cauley JA, et al. Is diabetes associated with cognitive impairment and cognitive decline among older women? Study of Osteoporotic Fractures Research Group. Arch Intern Med. 2000;160:174-180.
    • (2000) Arch Intern Med , vol.160 , pp. 174-180
    • Gregg, E.W.1    Yaffe, K.2    Cauley, J.A.3
  • 19
    • 1542373533 scopus 로고    scopus 로고
    • Prospective study of type 2 diabetes and cognitive decline in women aged 70-81 years
    • Logroscino G, Kang JH, Grodstein F. Prospective study of type 2 diabetes and cognitive decline in women aged 70-81 years. BMJ. 2004;328:548. (Pubitemid 38316623)
    • (2004) British Medical Journal , vol.328 , Issue.7439 , pp. 548-551
    • Logroscino, G.1    Kang, J.H.2    Grodstein, F.3
  • 20
    • 0035141946 scopus 로고    scopus 로고
    • Changes in cognitive abilities over a 4-year period are unfavorably affected in elderly diabetic subjects: Results of the epidemiology of vascular aging study
    • Fontbonne A, Berr C, Ducimetiere P, Alperovitch A. Changes in cognitive abilities over a 4-year period are unfavorably affected in elderly diabetic subjects: results of the Epidemiology of Vascular Aging Study. Diabetes Care. 2001;24:366-370. (Pubitemid 32119140)
    • (2001) Diabetes Care , vol.24 , Issue.2 , pp. 366-370
    • Fontbonne, A.1    Berr, C.2    Ducimetiere, P.3    Alperovitch, A.4
  • 22
    • 44649109475 scopus 로고    scopus 로고
    • Type 2 diabetes mellitus and cognitive decline in two large cohorts of community-dwelling older adults
    • Okereke OI, Kang JH, Cook NR, et al. Type 2 diabetes mellitus and cognitive decline in two large cohorts of community-dwelling older adults. J Am Geriatr Soc. 2008;56:1028-1036.
    • (2008) J Am Geriatr Soc , vol.56 , pp. 1028-1036
    • Okereke, O.I.1    Kang, J.H.2    Cook, N.R.3
  • 24
    • 2442424380 scopus 로고    scopus 로고
    • Diabetes Mellitus and Risk of Alzheimer Disease and Decline in Cognitive Function
    • DOI 10.1001/archneur.61.5.661
    • Arvanitakis Z, Wilson RS, Bienias JL, Evans DA, Bennett DA. Diabetes mellitus and risk of Alzheimer disease and decline in cognitive function. Arch Neurol. 2004;61:661-666. (Pubitemid 38637681)
    • (2004) Archives of Neurology , vol.61 , Issue.5 , pp. 661-666
    • Arvanitakis, Z.1    Wilson, R.S.2    Bienias, J.L.3    Evans, D.A.4    Bennett, D.A.5
  • 25
    • 4043104808 scopus 로고    scopus 로고
    • Comorbid type 2 diabetes mellitus and hypertension exacerbates cognitive decline: Evidence from a longitudinal study
    • Hassing LB, Hofer SM, Nilsson SE, et al. Comorbid type 2 diabetes mellitus and hypertension exacerbates cognitive decline: evidence from a longitudinal study. Age Ageing. 2004;33:355-361.
    • (2004) Age Ageing , vol.33 , pp. 355-361
    • Hassing, L.B.1    Hofer, S.M.2    Nilsson, S.E.3
  • 26
    • 33746691933 scopus 로고    scopus 로고
    • The impact of diabetes mellitus on cognitive decline in the oldest of the old: A prospective population-based study
    • DOI 10.1007/s00125-006-0333-1
    • van den BE, de Craen AJ, Biessels GJ, Gussekloo J, Westendorp RG. The impact of diabetes mellitus on cognitive decline in the oldest of the old: a prospective population-based study. Diabetologia. 2006;49:2015-2023. (Pubitemid 44168467)
    • (2006) Diabetologia , vol.49 , Issue.9 , pp. 2015-2023
    • Van Den Berg, E.1    De Craen, A.J.M.2    Biessels, G.J.3    Gussekloo, J.4    Westendorp, R.G.J.5
  • 27
    • 0842309993 scopus 로고    scopus 로고
    • Increased Risk of Type 2 Diabetes in Alzheimer Disease
    • DOI 10.2337/diabetes.53.2.474
    • Janson J, Laedtke T, Parisi JE, O'Brien P, Petersen RC, Butler PC. Increased risk of type 2 diabetes in Alzheimer disease. Diabetes. 2004;53:474-481. (Pubitemid 38174565)
    • (2004) Diabetes , vol.53 , Issue.2 , pp. 474-481
    • Janson, J.1    Laedtke, T.2    Parisi, J.E.3    O'Brien, P.4    Petersen, R.C.5    Butler, P.C.6
  • 28
    • 28444491100 scopus 로고    scopus 로고
    • Cognitive decline and dementia in diabetes - Systematic overview of prospective observational studies
    • DOI 10.1007/s00125-005-0023-4
    • Cukierman T, Gerstein HC, Williamson JD. Cognitive decline and dementia in diabetes-systematic overview of prospective observational studies. Diabetologia. 2005;48:2460-2469. (Pubitemid 41738208)
    • (2005) Diabetologia , vol.48 , Issue.12 , pp. 2460-2469
    • Cukierman, T.1    Gerstein, H.C.2    Williamson, J.D.3
  • 29
    • 33847061307 scopus 로고    scopus 로고
    • The effect of borderline diabetes on the risk of dementia and Alzheimer's disease
    • DOI 10.2337/db06-0879
    • Xu W, Qiu C, Winblad B, Fratiglioni L. The effect of borderline diabetes on the risk of dementia and Alzheimer's disease. Diabetes. 2007;56:211-216. (Pubitemid 46263130)
    • (2007) Diabetes , vol.56 , Issue.1 , pp. 211-216
    • Xu, W.1    Qiu, C.2    Winblad, B.3    Fratiglioni, L.4
  • 30
    • 3042589342 scopus 로고    scopus 로고
    • Change in cognitive function by glucose tolerance status in older adults: A 4-year prospective study of the Rancho Bernardo Study cohort
    • DOI 10.1001/archinte.164.12.1327
    • Kanaya AM, Barrett-Connor E, Gildengorin G, Yaffe K. Change in cognitive function by glucose tolerance status in older adults: a 4-year prospective study of the Rancho Bernardo study cohort. Arch Intern Med. 2004;164:1327-1333. (Pubitemid 38828884)
    • (2004) Archives of Internal Medicine , vol.164 , Issue.12 , pp. 1327-1333
    • Kanaya, A.M.1    Barrett-Connor, E.2    Gildengorin, G.3    Yaffe, K.4
  • 32
    • 0031025854 scopus 로고    scopus 로고
    • Is type II diabetes associated with an increased risk of cognitive dysfunction? a critical review of published studies
    • Strachan MW, Deary IJ, Ewing FM, Frier BM. Is type II diabetes associated with an increased risk of cognitive dysfunction? A critical review of published studies. Diabetes Care. 1997;20:438-445.
    • (1997) Diabetes Care , vol.20 , pp. 438-445
    • Strachan, M.W.1    Deary, I.J.2    Ewing, F.M.3    Frier, B.M.4
  • 33
    • 0032707190 scopus 로고    scopus 로고
    • Type 2 diabetes mellitus, cognitive impairment and dementia
    • Stewart R, Liolitsa D. Type 2 diabetes mellitus, cognitive impairment and dementia. Diabet Med. 1999;16:93-112.
    • (1999) Diabet Med , vol.16 , pp. 93-112
    • Stewart, R.1    Liolitsa, D.2
  • 34
    • 0037161304 scopus 로고    scopus 로고
    • The relationship of hypertension in the elderly to AD, vascular dementia, and cognitive function
    • Posner HB, Tang MX, Luchsinger J, Lantigua R, Stern Y, Mayeux R. The relationship of hypertension in the elderly to AD, vascular dementia, and cognitive function. Neurology. 2002;58:1175-1181. (Pubitemid 34411860)
    • (2002) Neurology , vol.58 , Issue.8 , pp. 1175-1181
    • Posner, H.B.1    Tang, M.-X.2    Luchsinger, J.3    Lantigua, R.4    Stern, Y.5    Mayeux, R.6
  • 38
    • 33845704496 scopus 로고    scopus 로고
    • Diabetes is related to cerebral infarction but not to AD pathology in older persons
    • DOI 10.1212/01.wnl.0000247053.45483.4e, PII 0000611420061212000014
    • Arvanitakis Z, Schneider JA, Wilson RS, et al. Diabetes is related to cerebral infarction but not to AD pathology in older persons. Neurology. 2006;67:1960-1965. (Pubitemid 44967371)
    • (2006) Neurology , vol.67 , Issue.11 , pp. 1960-1965
    • Arvanitakis, Z.1    Schneider, J.A.2    Wilson, R.S.3    Li, Y.4    Arnold, S.E.5    Wang, Z.6    Bennett, D.A.7
  • 39
    • 15544373905 scopus 로고    scopus 로고
    • White matter lesions on magnetic resonance imaging and their relationship with vascular risk factors in memory clinic attenders
    • DOI 10.1002/gps.1283
    • Lazarus R, Prettyman R, Cherryman G. White matter lesions on magnetic resonance imaging and their relationship with vascular risk factors in memory clinic attenders. Int J Geriatr Psychiatry. 2005;20:274-279. (Pubitemid 40426028)
    • (2005) International Journal of Geriatric Psychiatry , vol.20 , Issue.3 , pp. 274-279
    • Lazarus, R.1    Prettyman, R.2    Cherryman, G.3
  • 41
    • 44649198605 scopus 로고    scopus 로고
    • Insulin receptor signaling regulates synapse number, dendritic plasticity, and circuit function in vivo
    • Chiu SL, Chen CM, Cline HT. Insulin receptor signaling regulates synapse number, dendritic plasticity, and circuit function in vivo. Neuron. 2008;58:708-719.
    • (2008) Neuron , vol.58 , pp. 708-719
    • Chiu, S.L.1    Chen, C.M.2    Cline, H.T.3
  • 42
    • 0036458235 scopus 로고    scopus 로고
    • Synaptic plasticity in the diabetic brain: Advanced aging?
    • Artola A, Kamal A, Ramakers GM, et al. Synaptic plasticity in the diabetic brain: advanced aging? Prog Brain Res. 2002;138:305-314.
    • (2002) Prog Brain Res , vol.138 , pp. 305-314
    • Artola, A.1    Kamal, A.2    Ramakers, G.M.3
  • 43
    • 23844470857 scopus 로고    scopus 로고
    • Insulin modulates hippocampal activity-dependent synaptic plasticity in a N-methyl-D-aspartate receptor and phosphatidyl-inositol-3-kinase-dependent manner
    • DOI 10.1111/j.1471-4159.2005.03269.x
    • van der Heide LP, Kamal A, Artola A, Gispen WH, Ramakers GM. Insulin modulates hippocampal activity-dependent synaptic plasticity in a N-methyl-d-aspartate receptor and phosphatidyl-inositol-3-kinase-dependent manner. J Neurochem. 2005;94:1158-1166. (Pubitemid 41170602)
    • (2005) Journal of Neurochemistry , vol.94 , Issue.4 , pp. 1158-1166
    • Van Der Heide, L.P.1    Kamal, A.2    Artola, A.3    Gispen, W.H.4    Ramakers, G.M.J.5
  • 45
    • 33748295795 scopus 로고    scopus 로고
    • Insulin signaling in the central nervous system: Learning to survive
    • van der Heide LP, Ramakers GM, Smidt MP. Insulin signaling in the central nervous system: learning to survive. Prog Neurobiol. 2006;79:205-221.
    • (2006) Prog Neurobiol , vol.79 , pp. 205-221
    • Van Der Heide, L.P.1    Ramakers, G.M.2    Smidt, M.P.3
  • 46
    • 0025847968 scopus 로고
    • Insulin receptors in the central nervous system: Localization, signalling mechanisms and functional aspects
    • Unger JW, Livingston JN, Moss AM. Insulin receptors in the central nervous system: localization, signalling mechanisms and functional aspects. Prog Neurobiol. 1991;36:343-362.
    • (1991) Prog Neurobiol , vol.36 , pp. 343-362
    • Unger, J.W.1    Livingston, J.N.2    Moss, A.M.3
  • 47
    • 1242316296 scopus 로고    scopus 로고
    • Insulin and neurodegenerative disease: Shared and specific mechanisms
    • DOI 10.1016/S1474-4422(04)00681-7
    • Craft S, Watson GS. Insulin and neurodegenerative disease: shared and specific mechanisms. Lancet Neurol. 2004;3:169-178. (Pubitemid 38229951)
    • (2004) Lancet Neurology , vol.3 , Issue.3 , pp. 169-178
    • Craft, S.1    Watson, G.S.2
  • 48
  • 49
    • 36348935683 scopus 로고    scopus 로고
    • Soluble Abeta inhibits specific signal transduction cascades common to the insulin receptor pathway
    • DOI 10.1074/jbc.M610390200
    • Townsend M, Mehta T, Selkoe DJ. Soluble Abeta inhibits specific signal transduction cascades common to the insulin receptor pathway. J Biol Chem. 2007;282:33305-33312. (Pubitemid 350159548)
    • (2007) Journal of Biological Chemistry , vol.282 , Issue.46 , pp. 33305-33312
    • Townsend, M.1    Mehta, T.2    Selkoe, D.J.3
  • 50
    • 38049110692 scopus 로고    scopus 로고
    • Amyloid beta oligomers induce impairment of neuronal insulin receptors
    • Zhao WQ, De Felice FG, Fernandez S, et al. Amyloid beta oligomers induce impairment of neuronal insulin receptors. FASEB J. 2008;22:246-260.
    • (2008) FASEB J , vol.22 , pp. 246-260
    • Zhao, W.Q.1    De Felice, F.G.2    Fernandez, S.3
  • 51
    • 1842785179 scopus 로고    scopus 로고
    • Glucose metabolism and insulin receptor signal transduction in Alzheimer disease
    • DOI 10.1016/j.ejphar.2004.02.049, PII S0014299904002067
    • Hoyer S. Glucose metabolism and insulin receptor signal transduction in Alzheimer disease. Eur J Pharmacol. 2004;490:115-125. (Pubitemid 38482165)
    • (2004) European Journal of Pharmacology , vol.490 , Issue.1-3 , pp. 115-125
    • Hoyer, S.1
  • 52
    • 0034012017 scopus 로고    scopus 로고
    • Insulin regulates soluble amyloid precursor protein release via phosphatidyl inositol 3 kinase-dependent pathway
    • Solano DC, Sironi M, Bonfini C, Solerte SB, Govoni S, Racchi M. Insulin regulates soluble amyloid precursor protein release via phosphatidyl inositol 3 kinase-dependent pathway. FASEB J. 2000;14:1015-1022. (Pubitemid 30241680)
    • (2000) FASEB Journal , vol.14 , Issue.7 , pp. 1015-1022
    • Solano, D.C.1    Sironi, M.2    Bonfini, C.3    Solerte, S.B.4    Govoni, S.5    Racchi, M.6
  • 54
    • 0034669535 scopus 로고    scopus 로고
    • Intervening in atherogenesis: Lessons from diabetes
    • Vlassara H. Intervening in atherogenesis: lessons from diabetes. Hosp Pract (Off Ed). 2000;35:25-29.
    • (2000) Hosp Pract (Off Ed) , vol.35 , pp. 25-29
    • Vlassara, H.1
  • 56
    • 0032197142 scopus 로고    scopus 로고
    • Tau glycation is involved in aggregation of the protein but not in the formation of filaments
    • Ledesma MD, Perez M, Colaco C, Avila J. Tau glycation is involved in aggregation of the protein but not in the formation of filaments. Cell Mol Biol (Noisy-le-grand). 1998;44:1111-1116.
    • (1998) Cell Mol Biol (Noisy-le-grand) , vol.44 , pp. 1111-1116
    • Ledesma, M.D.1    Perez, M.2    Colaco, C.3    Avila, J.4
  • 60
    • 0028609520 scopus 로고
    • Advanced Maillard reaction end products, free radicals, and protein oxidation in Alzheimer's disease
    • Smith MA, Richey PL, Taneda S, et al. Advanced Maillard reaction end products, free radicals, and protein oxidation in Alzheimer's disease. Ann N Y Acad Sci. 1994;738:447-454.
    • (1994) Ann N Y Acad Sci , vol.738 , pp. 447-454
    • Smith, M.A.1    Richey, P.L.2    Taneda, S.3
  • 62
  • 63
    • 33644592598 scopus 로고    scopus 로고
    • Preserved cognition in patients with early Alzheimer disease and amnestic mild cognitive impairment during treatment with rosiglitazone: A preliminary study
    • Watson GS, Cholerton BA, Reger MA, et al. Preserved cognition in patients with early Alzheimer disease and amnestic mild cognitive impairment during treatment with rosiglitazone: a preliminary study. Am J Geriatr Psychiatry. 2005;13:950-958.
    • (2005) Am J Geriatr Psychiatry , vol.13 , pp. 950-958
    • Watson, G.S.1    Cholerton, B.A.2    Reger, M.A.3
  • 65
    • 34250212715 scopus 로고    scopus 로고
    • Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes
    • Nissen SE, Wolski K. Effects of rosiglitazone on the risk of myocardial infarction and death from cardiovasculr causes. N Engl J Med. 2007;356:2457-2471. (Pubitemid 46919772)
    • (2007) New England Journal of Medicine , vol.356 , Issue.24 , pp. 2457-2471
    • Nissen, S.E.1    Wolski, K.2
  • 69
    • 0032737079 scopus 로고    scopus 로고
    • Enhancement of memory in Alzheimer disease with insulin and somatostatin, but not glucose
    • Craft S, Asthana S, Newcomer JW, et al. Enhancement of memory in Alzheimer disease with insulin and somatostatin, but not glucose. Arch Gen Psychiatry. 1999;56:1135-1140.
    • (1999) Arch Gen Psychiatry , vol.56 , pp. 1135-1140
    • Craft, S.1    Asthana, S.2    Newcomer, J.W.3
  • 70
    • 0031907459 scopus 로고    scopus 로고
    • Cerebrospinal fluid and plasma insulin levels in Alzheimer's disease: Relationship to severity of dementia and apolipoprotein e genotype
    • Craft S, Peskind E, Schwartz MW, Schellenberg GD, Raskind M, Porte D, Jr. Cerebrospinal fluid and plasma insulin levels in Alzheimer's disease: relationship to severity of dementia and apolipoprotein E genotype. Neurology. 1998;50:164-168.
    • (1998) Neurology , vol.50 , pp. 164-168
    • Craft, S.1    Peskind, E.2    Schwartz, M.W.3    Schellenberg, G.D.4    Raskind, M.5    Porte Jr., D.6
  • 72
    • 31844434789 scopus 로고    scopus 로고
    • Effects of intranasal insulin on cognition in memory-impaired older adults: Modulation by APOE genotype
    • Reger MA, Watson GS, Frey WH, et al. Effects of intranasal insulin on cognition in memory-impaired older adults: modulation by APOE genotype. Neurobiol Aging. 2006;27:451-458.
    • (2006) Neurobiol Aging , vol.27 , pp. 451-458
    • Reger, M.A.1    Watson, G.S.2    Frey, W.H.3
  • 73
    • 34848877810 scopus 로고    scopus 로고
    • Intranasal insulin to improve memory function in humans
    • DOI 10.1159/000106378
    • Benedict C, Hallschmid M, Schultes B, Born J, Kern W. Intranasal insulin to improve memory function in humans. Neuroendocrinology. 2007;86:136-142. (Pubitemid 47494214)
    • (2007) Neuroendocrinology , vol.86 , Issue.2 , pp. 136-142
    • Benedict, C.1    Hallschmid, M.2    Schultes, B.3    Born, J.4    Kern, W.5
  • 74
    • 54049136095 scopus 로고    scopus 로고
    • Insulin combination with other diabetes medication is associated with less Alzheimer's neuropathology
    • In press
    • Beeri MS, Schmeidler J, Silverman JM, et al. Insulin combination with other diabetes medication is associated with less Alzheimer's neuropathology. Neurology. In press. 2008;71:750-757.
    • (2008) Neurology , vol.71 , pp. 750-757
    • Beeri, M.S.1    Schmeidler, J.2    Silverman, J.M.3
  • 75
    • 18144442184 scopus 로고    scopus 로고
    • Effect of the treatment of Type II diabetes mellitus on the development of cognitive impairment and dementia
    • CD003804
    • Areosa SA, Grimley EV. Effect of the treatment of Type II diabetes mellitus on the development of cognitive impairment and dementia. Cochrane Database Syst Rev. 2002:CD003804.
    • (2002) Cochrane Database Syst Rev
    • Areosa, S.A.1    Grimley, E.V.2
  • 76
    • 0038460824 scopus 로고    scopus 로고
    • Impact of antidiabetic medications on physical and cognitive functioning of older Mexican Americans with diabetes mellitus: A population-based cohort study
    • DOI 10.1016/S1047-2797(02)00464-7
    • Wu JH, Haan MN, Liang J, Ghosh D, Gonzalez HM, Herman WH. Impact of antidiabetic medications on physical and cognitive functioning of older Mexican Americans with diabetes mellitus: a population-based cohort study. Ann Epidemiol. 2003;13:369-376. (Pubitemid 36765399)
    • (2003) Annals of Epidemiology , vol.13 , Issue.5 , pp. 369-376
    • Wu, J.H.1    Haan, M.N.2    Liang, J.3    Ghosh, D.4    Gonzalez, H.M.5    Herman, W.H.6
  • 80
    • 0037322108 scopus 로고    scopus 로고
    • Low blood pressure and risk of dementia in the Kungsholmen project: A 6-year follow-up study
    • DOI 10.1001/archneur.60.2.223
    • Qiu C, von SE, Fastbom J, Winblad B, Fratiglioni L. Low blood pressure and risk of dementia in the Kungsholmen project: a 6-year follow-up study. Arch Neurol. 2003;60:223-228. (Pubitemid 36193966)
    • (2003) Archives of Neurology , vol.60 , Issue.2 , pp. 223-228
    • Qiu, C.1    Von Strauss, E.2    Fastbom, J.3    Winblad, B.4    Fratiglioni, L.5
  • 83
    • 0033786473 scopus 로고    scopus 로고
    • Metabolic cardiovascular syndrome and risk of dementia in Japanese-American elderly men. the Honolulu-Asia aging study
    • Kalmijn S, Foley D, White L, et al. Metabolic cardiovascular syndrome and risk of dementia in Japanese-American elderly men. The Honolulu-Asia aging study. Arterioscler Thromb Vasc Biol. 2000;20:2255-2260.
    • (2000) Arterioscler Thromb Vasc Biol , vol.20 , pp. 2255-2260
    • Kalmijn, S.1    Foley, D.2    White, L.3
  • 85
    • 0032779103 scopus 로고    scopus 로고
    • Cognitive decline in individuals with high blood pressure: A longitudinal study in the elderly. EVA Study Group. Epidemiology of Vascular Aging
    • Tzourio C, Dufouil C, Ducimetiere P, Alperovitch A. Cognitive decline in individuals with high blood pressure: a longitudinal study in the elderly. EVA Study Group. Epidemiology of Vascular Aging. Neurology. 1999;53:1948-1952.
    • (1999) Neurology , vol.53 , pp. 1948-1952
    • Tzourio, C.1    Dufouil, C.2    Ducimetiere, P.3    Alperovitch, A.4
  • 87
    • 2942590963 scopus 로고    scopus 로고
    • Blood pressure and late-life cognitive function change: A biracial longitudinal population study
    • Hebert LE, Scherr PA, Bennett DA, et al. Blood pressure and late-life cognitive function change: a biracial longitudinal population study. Neurology. 2004;62:2021-2024.
    • (2004) Neurology , vol.62 , pp. 2021-2024
    • Hebert, L.E.1    Scherr, P.A.2    Bennett, D.A.3
  • 88
    • 23844522541 scopus 로고    scopus 로고
    • Aggregation of vascular risk factors and risk of incident Alzheimer disease
    • Luchsinger JA, Reitz C, Honig LS, Tang MX, Shea S, eux R. Aggregation of vascular risk factors and risk of incident Alzheimer disease. Neurology. 2005;65:545-551.
    • (2005) Neurology , vol.65 , pp. 545-551
    • Luchsinger, J.A.1    Reitz, C.2    Honig, L.S.3    Tang, M.X.4    Shea, S.5    Eux, R.6
  • 89
    • 43449083774 scopus 로고    scopus 로고
    • Incidence of dementia, Alzheimer disease, and vascular dementia in a Japanese population: Radiation Effects Research Foundation adult health study
    • Yamada M, Mimori Y, Kasagi F, et al. Incidence of dementia, Alzheimer disease, and vascular dementia in a Japanese population: Radiation Effects Research Foundation adult health study. Neuroepidemiology. 2008;30:152-160.
    • (2008) Neuroepidemiology , vol.30 , pp. 152-160
    • Yamada, M.1    Mimori, Y.2    Kasagi, F.3
  • 90
    • 29144487953 scopus 로고    scopus 로고
    • Relation of blood pressure to risk of incident Alzheimer's disease and change in global cognitive function in older persons
    • DOI 10.1159/000089235
    • Shah RC, Wilson RS, Bienias JL, Arvanitakis Z, Evans DA, Bennett DA. Relation of blood pressure to risk of incident Alzheimer's disease and change in global cognitive function in older persons. Neuroepidemiology. 2006;26:30-36. (Pubitemid 41797935)
    • (2006) Neuroepidemiology , vol.26 , Issue.1 , pp. 30-36
    • Shah, R.C.1    Wilson, R.S.2    Bienias, J.L.3    Arvanitakis, Z.4    Evans, D.A.5    Bennett, D.A.6
  • 91
    • 0031708282 scopus 로고    scopus 로고
    • A population-based study on blood pressure and brain atrophy in 85- Year-olds
    • Skoog I, Andreasson LA, Landahl S, Lernfelt B. A population-based study on blood pressure and brain atrophy in 85-year-olds. Hypertension. 1998;32:404-409. (Pubitemid 28429126)
    • (1998) Hypertension , vol.32 , Issue.3 , pp. 404-409
    • Skoog, I.1    Andreasson, L.-A.2    Landahl, S.3    Lernfelt, B.4
  • 93
    • 0032816804 scopus 로고    scopus 로고
    • Occurrence and progression of dementia in a community population aged 75 years and older: Relationship of antihypertensive medication use
    • DOI 10.1001/archneur.56.8.991
    • Guo Z, Fratiglioni L, Zhu L, Fastbom J, Winblad B, Viitanen M. Occurrence and progression of dementia in a community population aged 75 years and older: relationship of antihypertensive medication use. Arch Neurol. 1999;56:991-996. (Pubitemid 29374817)
    • (1999) Archives of Neurology , vol.56 , Issue.8 , pp. 991-996
    • Guo, Z.1    Fratiglioni, L.2    Zhu, L.3    Fastbom, J.4    Winblad, B.5    Viitanen, M.6
  • 94
    • 33646433026 scopus 로고    scopus 로고
    • Antihypertensive medication use and incident Alzheimer disease: The Cache County Study
    • Khachaturian AS, Zandi PP, Lyketsos CG, et al. Antihypertensive medication use and incident Alzheimer disease: the Cache County Study. Arch Neurol. 2006;63:686-692.
    • (2006) Arch Neurol , vol.63 , pp. 686-692
    • Khachaturian, A.S.1    Zandi, P.P.2    Lyketsos, C.G.3
  • 96
    • 0035242698 scopus 로고    scopus 로고
    • Apolipoprotein e genotypes and the incidence of Alzheimer's disease among persons aged 75 years and older: Variation by use of antihypertensive medication?
    • Guo Z, Fratiglioni L, Viitanen M, et al. Apolipoprotein E genotypes and the incidence of Alzheimer's disease among persons aged 75 years and older: variation by use of antihypertensive medication? Am J Epidemiol. 2001 1;153:225-231.
    • (2001) Am J Epidemiol , vol.1 , Issue.153 , pp. 225-231
    • Guo, Z.1    Fratiglioni, L.2    Viitanen, M.3
  • 97
    • 33646696167 scopus 로고    scopus 로고
    • Reducing the risk of dementia: Efficacy of long-term treatment of hypertension
    • DOI 10.1161/01.STR.0000217653.01615.93, PII 0000767020060500000017
    • Peila R, White LR, Masaki K, Petrovitch H, Launer LJ. Reducing the risk of dementia: efficacy of long-term treatment of hypertension. Stroke. 2006;37:1165-1170. (Pubitemid 43731856)
    • (2006) Stroke , vol.37 , Issue.5 , pp. 1165-1170
    • Peila, R.1    White, L.R.2    Masaki, K.3    Petrovitch, H.4    Launer, L.J.5
  • 98
    • 0042836671 scopus 로고    scopus 로고
    • Combined effects of APOE genotype, blood pressure, and antihypertensive drug use on incident AD
    • Qiu C, Winblad B, Fastbom J, Fratiglioni L. Combined effects of APOE genotype, blood pressure, and antihypertensive drug use on incident AD. Neurology. 2003 9;61:655-660. (Pubitemid 37082603)
    • (2003) Neurology , vol.61 , Issue.5 , pp. 655-660
    • Qiu, C.1    Winblad, B.2    Fastbom, J.3    Fratiglioni, L.4
  • 99
    • 0025831464 scopus 로고
    • Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hypertension. Final results of the Systolic Hypertension in the Elderly Program (SHEP)
    • SHEP Cooperative Research Group
    • Prevention of stroke by antihypertensive drug treatment in older persons with isolated systolic hypertension. Final results of the Systolic Hypertension in the Elderly Program (SHEP). SHEP Cooperative Research Group. JAMA. 1991;265:3255-3264.
    • (1991) JAMA , vol.265 , pp. 3255-3264
  • 100
    • 0028006802 scopus 로고
    • Impact of the treatment of isolated systolic hypertension on behavioral variables. Results from the systolic hypertension in the elderly program
    • Applegate WB, Pressel S, Wittes J, et al. Impact of the treatment of isolated systolic hypertension on behavioral variables. Results from the systolic hypertension in the elderly program. Arch Intern Med. 1994;154:2154-2160.
    • (1994) Arch Intern Med , vol.154 , pp. 2154-2160
    • Applegate, W.B.1    Pressel, S.2    Wittes, J.3
  • 101
    • 0029988543 scopus 로고    scopus 로고
    • Is the cognitive function of older patients affected by antihypertensive treatment? Results from 54 months of the Medical Research Council's trial of hypertension in older adults
    • Prince MJ, Bird AS, Blizard RA, Mann AH. Is the cognitive function of older patients affected by antihypertensive treatment? Results from 54 months of the Medical Research Council's trial of hypertension in older adults. BMJ. 1996;312:801-805.
    • (1996) BMJ , vol.312 , pp. 801-805
    • Prince, M.J.1    Bird, A.S.2    Blizard, R.A.3    Mann, A.H.4
  • 104
    • 46949106968 scopus 로고    scopus 로고
    • Incident dementia and blood pressure lowering in the Hypertension in the Very Elderly Trial cognitive function assessment (HYVET-COG): A double-blind, placebo controlled trial
    • Peters R, Beckett N, Forette F, et al. Incident dementia and blood pressure lowering in the Hypertension in the Very Elderly Trial cognitive function assessment (HYVET-COG): a double-blind, placebo controlled trial. Lancet Neurol. 2008;7:683-689.
    • (2008) Lancet Neurol , vol.7 , pp. 683-689
    • Peters, R.1    Beckett, N.2    Forette, F.3
  • 105
    • 12544254102 scopus 로고    scopus 로고
    • Association between blood pressure, white matter lesions, and atrophy of the medial temporal lobe
    • den HT, Launer LJ, Prins ND, et al. Association between blood pressure, white matter lesions, and atrophy of the medial temporal lobe. Neurology. 2005;64:263-267.
    • (2005) Neurology , vol.64 , pp. 263-267
    • Den, H.T.1    Launer, L.J.2    Prins, N.D.3
  • 107
    • 0034594470 scopus 로고    scopus 로고
    • Midlife blood pressure and neuritic plaques, neurofibrillary tangles, and brain weight at death: The HAAS. Honolulu-Asia aging Study
    • Petrovitch H, White LR, Izmirilian G, et al. Midlife blood pressure and neuritic plaques, neurofibrillary tangles, and brain weight at death: the HAAS. Honolulu-Asia aging Study. Neurobiol Aging. 2000;21:57-62.
    • (2000) Neurobiol Aging , vol.21 , pp. 57-62
    • Petrovitch, H.1    White, L.R.2    Izmirilian, G.3
  • 108
    • 0029020269 scopus 로고
    • Increased incidence of neurofibrillary tangles (NFT) in non-demented individuals with hypertension
    • Sparks DL, Scheff SW, Liu H, Landers TM, Coyne CM, Hunsaker JC, III. Increased incidence of neurofibrillary tangles (NFT) in non-demented individuals with hypertension. J Neurol Sci. 1995;131:162-169.
    • (1995) J Neurol Sci , vol.131 , pp. 162-169
    • Sparks, D.L.1    Scheff, S.W.2    Liu, H.3    Landers, T.M.4    Coyne, C.M.5    Hunsaker III, J.C.6
  • 109
    • 0034042913 scopus 로고    scopus 로고
    • Cerebral hypoperfusion, capillary degeneration, and development of Alzheimer disease
    • de la Torre JC. Cerebral hypoperfusion, capillary degeneration, and development of Alzheimer disease. Alzheimer Dis Assoc Disord. 2000;14 Suppl 1:S72-S81.
    • (2000) Alzheimer Dis Assoc Disord , vol.14 , Issue.SUPPL. 1
    • De La Torre, J.C.1
  • 110
    • 0028865755 scopus 로고
    • Ischemic stress induces deposition of amyloid beta immunoreactivity in human brain
    • Jendroska K, Poewe W, Daniel SE, et al. Ischemic stress induces deposition of amyloid beta immunoreactivity in human brain. Acta Neuropathol. 1995;90:461-466.
    • (1995) Acta Neuropathol , vol.90 , pp. 461-466
    • Jendroska, K.1    Poewe, W.2    Daniel, S.E.3
  • 111
    • 0034064133 scopus 로고    scopus 로고
    • Critically attained threshold of cerebral hypoperfusion: Can it cause Alzheimer's disease?
    • de la Torre JC. Critically attained threshold of cerebral hypoperfusion: can it cause Alzheimer's disease? Ann N Y Acad Sci. 2000;903:424-436.
    • (2000) Ann N Y Acad Sci , vol.903 , pp. 424-436
    • De La Torre, J.C.1
  • 113
    • 3042538272 scopus 로고    scopus 로고
    • Midlife blood pressure and the risk of hippocampal atrophy: The Honolulu Asia aging study
    • DOI 10.1161/01.HYP.0000132475.32317.bb
    • Korf ES, White LR, Scheltens P, Launer LJ. Midlife blood pressure and the risk of hippocampal atrophy: the Honolulu Asia Aging Study. Hypertension. 2004;44:29-34. (Pubitemid 38823483)
    • (2004) Hypertension , vol.44 , Issue.1 , pp. 29-34
    • Korf, E.S.C.1    White, L.R.2    Scheltens, P.3    Launer, L.J.4
  • 114
    • 66149096646 scopus 로고    scopus 로고
    • Less Alzheimer's disease neuropathology in medicated hypertensive than non hypertensive persons
    • In press
    • Hoffman LB, Schmeidler J, Lesser GT, et al. Less Alzheimer's disease neuropathology in medicated hypertensive than non hypertensive persons. Neurology. 2009. In press.
    • (2009) Neurology
    • Hoffman, L.B.1    Schmeidler, J.2    Lesser, G.T.3
  • 115
  • 116
    • 33846061128 scopus 로고    scopus 로고
    • Twenty-six-year change in total cholesterol levels and incident dementia: The Honolulu-Asia aging study
    • DOI 10.1001/archneur.64.1.103
    • Stewart R, White LR, Xue QL, Launer LJ. Twenty-six-year change in total cholesterol levels and incident dementia: the Honolulu-Asia Aging Study. Arch Neurol. 2007;64:103-107. (Pubitemid 46072431)
    • (2007) Archives of Neurology , vol.64 , Issue.1 , pp. 103-107
    • Stewart, R.1    White, L.R.2    Xue, Q.-L.3    Launer, L.J.4
  • 118
    • 18844457544 scopus 로고    scopus 로고
    • High total cholesterol levels in late life associated with a reduced risk of dementia
    • DOI 10.1212/01.WNL.0000161870.78572.A5
    • Mielke MM, Zandi PP, Sjogren M, et al. High total cholesterol levels in late life associated with a reduced risk of dementia. Neurology. 2005;64:1689-1695. (Pubitemid 40695799)
    • (2005) Neurology , vol.64 , Issue.10 , pp. 1689-1695
    • Mielke, M.M.1    Zandi, P.P.2    Sjogren, M.3    Gustafson, D.4    Ostling, S.5    Steen, B.6    Skoog, I.7
  • 121
    • 0036186663 scopus 로고    scopus 로고
    • Serum lipoprotein levels, statin use, and cognitive function in older women
    • Yaffe K, Barrett-Connor E, Lin F, Grady D. Serum lipoprotein levels, statin use, and cognitive function in older women. Arch Neurol. 2002;59:378-384. (Pubitemid 34208144)
    • (2002) Archives of Neurology , vol.59 , Issue.3 , pp. 378-384
    • Yaffe, K.1    Barrett-Connor, E.2    Lin, F.3    Grady, D.4
  • 122
    • 17644412919 scopus 로고    scopus 로고
    • Impact of plasma lipids and time on memory performance in healthy elderly without dementia
    • Reitz C, Luchsinger J, Tang MX, Manly J, Mayeux R. Impact of plasma lipids and time on memory performance in healthy elderly without dementia. Neurology. 2005;64:1378-1383. (Pubitemid 40570505)
    • (2005) Neurology , vol.64 , Issue.8 , pp. 1378-1383
    • Reitz, C.1    Luchsinger, J.2    Tang, M.-X.3    Manly, J.4    Mayeux, R.5
  • 125
    • 2442489033 scopus 로고    scopus 로고
    • Relation of plasma lipids to Alzheimer disease and vascular dementia
    • Reitz C, Tang MX, Luchsinger J, eux R. Relation of plasma lipids to Alzheimer disease and vascular dementia. Arch Neurol. 2004;61:705-714.
    • (2004) Arch Neurol , vol.61 , pp. 705-714
    • Reitz, C.1    Tang, M.X.2    Luchsinger, J.3    Eux, R.4
  • 126
    • 0033546660 scopus 로고    scopus 로고
    • APOE genotype, plasma lipids, lipoproteins, and AD in community elderly
    • Romas SN, Tang MX, Berglund L, eux R. APOE genotype, plasma lipids, lipoproteins, and AD in community elderly. Neurology. 1999;53:517-521.
    • (1999) Neurology , vol.53 , pp. 517-521
    • Romas, S.N.1    Tang, M.X.2    Berglund, L.3    Eux, R.4
  • 127
    • 0345669752 scopus 로고    scopus 로고
    • Alzheimer's disease: The cholesterol connection
    • Puglielli L, Tanzi RE, Kovacs DM. Alzheimer's disease: the cholesterol connection. Nat Neurosci. 2003;6:345-351.
    • (2003) Nat Neurosci , vol.6 , pp. 345-351
    • Puglielli, L.1    Tanzi, R.E.2    Kovacs, D.M.3
  • 128
    • 0033958076 scopus 로고    scopus 로고
    • Serum cholesterol, APOE genotype, and the risk of Alzheimer's disease: A population-based study of African Americans
    • Evans RM, Emsley CL, Gao S, et al. Serum cholesterol, APOE genotype, and the risk of Alzheimer's disease: a population-based study of African Americans. Neurology. 2000;54:240-242.
    • (2000) Neurology , vol.54 , pp. 240-242
    • Evans, R.M.1    Emsley, C.L.2    Gao, S.3
  • 129
    • 33644911218 scopus 로고    scopus 로고
    • Cholesterol, APOE genotype, and Alzheimer disease: An epidemiologic study of Nigerian Yoruba
    • Hall K, Murrell J, Ogunniyi A, et al. Cholesterol, APOE genotype, and Alzheimer disease: an epidemiologic study of Nigerian Yoruba. Neurology. 2006;66:223-227.
    • (2006) Neurology , vol.66 , pp. 223-227
    • Hall, K.1    Murrell, J.2    Ogunniyi, A.3
  • 131
    • 58149168436 scopus 로고    scopus 로고
    • Serum lipids are related to Alzheimer's pathology in nursing home residents
    • Lesser GT, Haroutunian V, Purohit DP, et al. Serum lipids are related to Alzheimer's pathology in nursing home residents. Dement Geriatr Cogn Disord. 2009 8;27:42-49.
    • (2009) Dement Geriatr Cogn Disord , vol.8 , Issue.27 , pp. 42-49
    • Lesser, G.T.1    Haroutunian, V.2    Purohit, D.P.3
  • 133
    • 0035940542 scopus 로고    scopus 로고
    • Cholesterol and neuropathologic markers of AD: A population-based autopsy study
    • Launer LJ, White LR, Petrovitch H, Ross GW, Curb JD. Cholesterol and neuropathologic markers of AD: a population-based autopsy study. Neurology. 2001;57:1447-1452. (Pubitemid 32995727)
    • (2001) Neurology , vol.57 , Issue.8 , pp. 1447-1452
    • Launer, L.J.1    White, L.R.2    Petrovitch, H.3    Ross, G.W.4    Curb, J.D.5
  • 136
    • 7544249658 scopus 로고    scopus 로고
    • How NSAIDs might prevent Alzheimer's disease
    • Bradbury J. How NSAIDs might prevent Alzheimer's disease. Lancet Neurol. 2004;3:638.
    • (2004) Lancet Neurol , vol.3 , pp. 638
    • Bradbury, J.1
  • 137
    • 58249089520 scopus 로고    scopus 로고
    • Statins are associated with a reduced risk of Alzheimer disease regardless of lipophilicity. the Rotterdam Study
    • Haag MD, Hofman A, Koudstaal PJ, Strieker BH, Breteler MM. Statins are associated with a reduced risk of Alzheimer disease regardless of lipophilicity. The Rotterdam Study. J Neurol Neurosurg Psychiatry. 2009;80:13-17.
    • (2009) J Neurol Neurosurg Psychiatry , vol.80 , pp. 13-17
    • Haag, M.D.1    Hofman, A.2    Koudstaal, P.J.3    Strieker, B.H.4    Breteler, M.M.5
  • 139
    • 67649252917 scopus 로고    scopus 로고
    • Use of statins and incidence of dementia and cognitive impairment without dementia in a cohort study
    • Cramer C, Haan MN, Galea S, Langa KM, Kalbfleisch JD. Use of statins and incidence of dementia and cognitive impairment without dementia in a cohort study. Neurology. 2008;71:344-350.
    • (2008) Neurology , vol.71 , pp. 344-350
    • Cramer, C.1    Haan, M.N.2    Galea, S.3    Langa, K.M.4    Kalbfleisch, J.D.5
  • 142
    • 84921537471 scopus 로고    scopus 로고
    • Statins for the prevention of Alzheimer's disease
    • CD003160
    • Scott HD, Laake K. Statins for the prevention of Alzheimer's disease. Cochrane Database Syst Rev. 2001:CD003160.
    • (2001) Cochrane Database Syst Rev
    • Scott, H.D.1    Laake, K.2
  • 143
    • 0036321773 scopus 로고    scopus 로고
    • Early inflammation and dementia: A 25-year follow-up of the Honolulu-Asia Aging Study
    • DOI 10.1002/ana.10265
    • Schmidt R, Schmidt H, Curb JD, Masaki K, White LR, Launer LJ. Early inflammation and dementia: a 25-year follow-up of the Honolulu-Asia Aging Study. Ann Neurol. 2002;52:168-174. (Pubitemid 34810596)
    • (2002) Annals of Neurology , vol.52 , Issue.2 , pp. 168-174
    • Schmidt, R.1    Schmidt, H.2    Curb, J.D.3    Masaki, K.4    White, L.R.5    Launer, L.J.6
  • 147
    • 0037072285 scopus 로고    scopus 로고
    • Interleukin-6 and risk of cognitive decline: Macarthur studies of successful aging
    • Weaver JD, Huang MH, Albert M, Harris T, Rowe JW, Seeman TE. Interleukin-6 and risk of cognitive decline: MacArthur studies of successful aging. Neurology. 2002;59:371-378. (Pubitemid 34857929)
    • (2002) Neurology , vol.59 , Issue.3 , pp. 371-378
    • Weaver, J.D.1    Huang, M.-H.2    Albert, M.3    Harris, T.4    Rowe, J.W.5    Seeman, T.E.6
  • 150
    • 34247625735 scopus 로고    scopus 로고
    • Systemic markers of inflammation and cognitive decline in old age
    • Schram MT, Euser SM, de Craen AJ, et al. Systemic markers of inflammation and cognitive decline in old age. J Am Geriatr Soc. 2007;55:708-716.
    • (2007) J Am Geriatr Soc , vol.55 , pp. 708-716
    • Schram, M.T.1    Euser, S.M.2    De Craen, A.J.3
  • 152
    • 33947727192 scopus 로고    scopus 로고
    • Interleukins, inflammation, and mechanisms of Alzheimer's disease
    • Weisman D, Hakimian E, Ho GJ. Interleukins, inflammation, and mechanisms of Alzheimer's disease. Vitam Horm. 2006;74:505-530.
    • (2006) Vitam Horm , vol.74 , pp. 505-530
    • Weisman, D.1    Hakimian, E.2    Ho, G.J.3
  • 153
    • 0036850023 scopus 로고    scopus 로고
    • Neuroinflammation in Alzheimer's disease and prion disease
    • Eikelenboom P, Bate C, van Gool WA, et al. Neuroinflammation in Alzheimer's disease and prion disease. Glia. 2002;40:232-239.
    • (2002) Glia , vol.40 , pp. 232-239
    • Eikelenboom, P.1    Bate, C.2    Van Gool, W.A.3
  • 155
    • 0042835437 scopus 로고    scopus 로고
    • Lipopolysaccharide-induced-neuroinflammation increases intracellular accumulation of amyloid precursor protein and amyloid beta peptide in APPswe transgenic mice
    • DOI 10.1016/S0969-9961(03)00069-X
    • Sheng JG, Bora SH, Xu G, Borchelt DR, Price DL, Koliatsos VE. Lipopolysaccharide-induced-neuroinflammation increases intracellular accumulation of amyloid precursor protein and amyloid beta peptide in APPswe transgenic mice. Neurobiol Dis. 2003;14:133-145. (Pubitemid 37103187)
    • (2003) Neurobiology of Disease , vol.14 , Issue.1 , pp. 133-145
    • Sheng, J.G.1    Bora, S.H.2    Xu, G.3    Borchelt, D.R.4    Price, D.L.5    Koliatsos, V.E.6
  • 156
    • 0035693924 scopus 로고    scopus 로고
    • Inflammation, autotoxicity and Alzheimer disease
    • McGeer PL, McGeer EG. Inflammation, autotoxicity and Alzheimer disease. Neurobiol Aging. 2001;22:799-809.
    • (2001) Neurobiol Aging , vol.22 , pp. 799-809
    • McGeer, P.L.1    McGeer, E.G.2
  • 159
    • 0033551547 scopus 로고    scopus 로고
    • A double-blind, placebo-controlled trial of diclofenac/misoprostol in Alzheimer's disease
    • Scharf S, Mander A, Ugoni A, Vajda F, Christophidis N. A double-blind, placebo-controlled trial of diclofenac/misoprostol in Alzheimer's disease. Neurology. 1999;53:197-201. (Pubitemid 29329671)
    • (1999) Neurology , vol.53 , Issue.1 , pp. 197-201
    • Scharf, S.1    Mander, A.2    Ugoni, A.3    Vajda, F.4    Christophidis, N.5
  • 161
    • 0037046179 scopus 로고    scopus 로고
    • Randomized pilot study of nimesulide treatment in alzheimer's disease
    • Aisen PS, Schmeidler J, Pasinetti GM. Randomized pilot study of nimesulide treatment in Alzheimer's disease. Neurology. 2002 9;58:1050-1054. (Pubitemid 34298544)
    • (2002) Neurology , vol.58 , Issue.7 , pp. 1050-1054
    • Aisen, P.S.1    Schmeidler, J.2    Pasinetti, G.M.3
  • 163
    • 47549107705 scopus 로고    scopus 로고
    • Cognitive function over time in the Alzheimer's disease anti-inflammatory prevention trial (ADAPT): Results of a randomized, controlled trial of naproxen and celecoxib
    • DOI 10.1001/archneur.2008.65.7.nct70006
    • Martin BK, Szekely C, Brandt J, et al. Cognitive function over time in the Alzheimer's Disease Anti-inflammatory Prevention Trial (ADAPT): results of a randomized, controlled trial of naproxen and celecoxib. Arch Neurol. 2008;65:896-905. (Pubitemid 352008472)
    • (2008) Archives of Neurology , vol.65 , Issue.7 , pp. 896-905
    • Martin, B.K.1    Szekely, C.2    Brandt, J.3    Piantadosi, S.4    Breitner, J.C.S.5    Craft, S.6    Evans, D.7    Green, R.8    Mullan, M.9


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.