Chronic treatment with polychlorinated biphenyls (PCB) during pregnancy and lactation in the rat. Part 2: Effects on reproductive parameters, on sex behavior, on memory retention and on hypothalamic expression of aromatase and 5alpha-reductases in the offspring

Toxicology and Applied Pharmacology

Volumn 239, Issue 1, 2009, Pages 46-54

  Colciago, A ^a   Casati, L ^a   Mornati, O ^a   Vergoni, A V ^b   Santagostino, A ^c   Celotti, F ^a   Negri Cesi, P ^a  

^a UNIVERSITY OF MILAN   (Italy)

^b UNIVERSITY OF MODENA AND REGGIO EMILIA   (Italy)

^c UNIVERSITY OF MILANO BICOCCA   (Italy)

Author keywords

5alpha reductase; Aromatase; Brain sex differentiation; Dimorphism; PCB; Perinatal exposure

Indexed keywords

AROMATASE; POLYCHLORINATED BIPHENYL DERIVATIVE; STEROID 5ALPHA REDUCTASE 1; STEROID 5ALPHA REDUCTASE 2;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ANXIETY; ARTICLE; CONTROLLED STUDY; DEPRESSION; FEMALE; HYPOTHALAMUS; LACTATION; LEARNING; LOCOMOTION; MALE; MEMORY CONSOLIDATION; NEUROBIOLOGY; NEUROENDOCRINE SYSTEM; NONHUMAN; PREGNANCY; PROGENY; PROTEIN EXPRESSION; PUBERTY; RAT; REPRODUCTION; SEX DIFFERENCE; SEXUAL BEHAVIOR;

AGING; ANIMALS; AROMATASE; CHOLESTENONE 5 ALPHA-REDUCTASE; DOSE-RESPONSE RELATIONSHIP, DRUG; ENDOCRINE DISRUPTORS; FEMALE; HYPOTHALAMUS; LACTATION; MALE; MATERNAL EXPOSURE; MAZE LEARNING; MEMORY; MOTOR ACTIVITY; POLYCHLORINATED BIPHENYLS; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS; RATS, SPRAGUE-DAWLEY; REPRODUCTION; SEX CHARACTERISTICS; SEXUAL BEHAVIOR, ANIMAL;

ANIMALIA; RATTUS;

EID: 67650679260     PISSN: 0041008X     EISSN: 10960333     Source Type: Journal    
DOI: 10.1016/j.taap.2009.04.023     Document Type: Article

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