Synthesis and preliminary evaluation of duocarmycin analogues incorporating the 1,2,11,11a-tetrahydrocyclopropa[c]naphtho[2,3-e]indol-4-one (CNI) and 1,2,11,11a-tetrahydrocyclopropa[c]naphtho[1,2-e]indol-4-one (iso-CNI) alkylation subunits

Tetrahedron

Volumn 65, Issue 33, 2009, Pages 6591-6599

  Gauss, Carla M ^a   Hamasaki, Akiyuki ^a   Parrish, Jay P ^a   MacMillan, Karen S ^a   Rayl, Thomas J ^a   Hwang, Inkyu ^a   Boger, Dale L ^a  

^a SCRIPPS RESEARCH INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,2,11,11A TETRAHYDROCYCLOPROPA[C]NAPHTHO[1,2 E]INDOL 4 ONE; 1,2,11,11A TETRAHYDROCYCLOPROPA[C]NAPHTHO[2,3 E]INDOL 4 ONE; ANTHRACENE DERIVATIVE; DUOCARMYCIN DERIVATIVE; PHENANTHRENE DERIVATIVE; RACHELMYCIN; UNCLASSIFIED DRUG;

ARTICLE; CYTOTOXICITY; DNA ALKYLATION; DRUG STRUCTURE; DRUG SYNTHESIS; PRIORITY JOURNAL; SOLVOLYSIS;

EID: 67650260769     PISSN: 00404020     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.tet.2009.02.065     Document Type: Article

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