Adrenomedullin reduces intestinal epithelial permeability in vivo and in vitro

American Journal of Physiology - Gastrointestinal and Liver Physiology

Volumn 297, Issue 1, 2009, Pages

  Temmesfeld Wollbrück, Bettina ^a   Brell, Bernhard ^a   Dohna, Corinna Zu ^a   Dorenberg, Martin ^a   Hocke, Andreas C ^a   Martens, Holger ^b   Klar, Jürgen ^c   Suttorp, Norbert ^a   Hippenstiel, Stefan ^a  

^a CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

^b FREIE UNIVERSITÄT BERLIN   (Germany)

^c Nycomed   (Germany)

Author keywords

Cyclic AMP; Intestinal permeability; Sepsis; Transepithelial resistance

Indexed keywords

ADENYLATE CYCLASE; ADRENOMEDULLIN; CYCLIC AMP; DEXTRAN; FORSKOLIN; HYDROGEN PEROXIDE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE P38; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHODIESTERASE; PHOSPHODIESTERASE III; PHOSPHODIESTERASE IV; PROTEIN KINASE C; VIRULENCE FACTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BACTERIAL TRANSLOCATION; CELL STRAIN CACO 2; CONTROLLED STUDY; CRITICAL ILLNESS; DEGRADATION; ELECTRIC RESISTANCE; ENDOTHELIUM; ENZYME INHIBITION; IN VITRO STUDY; IN VIVO STUDY; INFLAMMATION; INTESTINE EPITHELIUM; INTESTINE MUCOSA PERMEABILITY; MALE; NONHUMAN; PRIORITY JOURNAL; RAT; SEPSIS; SEPTIC SHOCK; STAPHYLOCOCCUS AUREUS; SYSTEMIC CIRCULATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ADRENOMEDULLIN; ANIMALS; BACTERIAL TOXINS; BACTERIAL TRANSLOCATION; CACO-2 CELLS; COLON; CYCLIC AMP; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 3; CYCLIC NUCLEOTIDE PHOSPHODIESTERASES, TYPE 4; DEXTRANS; DISEASE MODELS, ANIMAL; ENZYME ACTIVATORS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FLUORESCEIN-5-ISOTHIOCYANATE; FLUORESCENT DYES; HEMOLYSIN PROTEINS; HUMANS; HYDROGEN PEROXIDE; ILEUM; INFUSIONS, INTRAVENOUS; INTESTINAL MUCOSA; MALE; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PERMEABILITY; PHOSPHODIESTERASE INHIBITORS; PROTEIN KINASE C; PROTEIN KINASE INHIBITORS; RATS; RATS, SPRAGUE-DAWLEY; SHOCK, SEPTIC; SIGNAL TRANSDUCTION; TIME FACTORS;

EID: 67650090899     PISSN: 01931857     EISSN: 15221547     Source Type: Journal    
DOI: 10.1152/ajpgi.90532.2008     Document Type: Article

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