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Volumn 109, Issue 2, 2004, Pages 242-248

Adrenomedullin Infusion Attenuates Myocardial Ischemia/Reperfusion Injury Through the Phosphatidylinositol 3-Kinase/Akt-Dependent Pathway

Author keywords

Apoptosis; Hemodynamics; Myocardial infarction; Peptides; Reperfusion

Indexed keywords

ADRENOMEDULLIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; WORTMANNIN;

EID: 9144253125     PISSN: 00097322     EISSN: None     Source Type: Journal    
DOI: 10.1161/01.CIR.0000109214.30211.7C     Document Type: Article
Times cited : (149)

References (25)
  • 1
    • 0027197671 scopus 로고
    • Adrenomedullin: A novel hypotensive peptide isolated from human pheochromocytoma
    • Kitamura K, Kangawa K, Kawamoto M, et al. Adrenomedullin: a novel hypotensive peptide isolated from human pheochromocytoma. Biochem Biophys Res Commun. 1993;192:553-560.
    • (1993) Biochem Biophys Res Commun , vol.192 , pp. 553-560
    • Kitamura, K.1    Kangawa, K.2    Kawamoto, M.3
  • 2
    • 0028127987 scopus 로고
    • Distribution and characterization of immunoreactive adrenomedullin in human tissue and plasma
    • Ichiki Y, Kitamura K, Kangawa K, et al. Distribution and characterization of immunoreactive adrenomedullin in human tissue and plasma. FEBS Lett. 1994;338:6-10.
    • (1994) FEBS Lett , vol.338 , pp. 6-10
    • Ichiki, Y.1    Kitamura, K.2    Kangawa, K.3
  • 3
    • 0027933172 scopus 로고
    • Distribution and characterization of immunoreactive rat adrenomedullin in tissue and plasma
    • Sakata J, Shimokubo T, Kitamura K, et al. Distribution and characterization of immunoreactive rat adrenomedullin in tissue and plasma. FEBS Lett. 1994;352:105-108.
    • (1994) FEBS Lett , vol.352 , pp. 105-108
    • Sakata, J.1    Shimokubo, T.2    Kitamura, K.3
  • 4
    • 7144227966 scopus 로고    scopus 로고
    • Increased plasma adrenomedullin levels in patients with acute myocardial infarction in proportion to the clinical severity
    • Miyao Y, Nishikimi T, Goto Y, et al. Increased plasma adrenomedullin levels in patients with acute myocardial infarction in proportion to the clinical severity. Heart. 1998;79:39-44.
    • (1998) Heart , vol.79 , pp. 39-44
    • Miyao, Y.1    Nishikimi, T.2    Goto, Y.3
  • 5
    • 0033993836 scopus 로고    scopus 로고
    • Cardiac adrenomedullin gene expression and peptide accumulation after acute myocardial infarction in rats
    • Nagaya N, Nishikimi T, Yoshihara F, et al. Cardiac adrenomedullin gene expression and peptide accumulation after acute myocardial infarction in rats. Am J Physiol Regul Integr Comp Physiol. 2000;278:R1019-R1026.
    • (2000) Am J Physiol Regul Integr Comp Physiol , vol.278
    • Nagaya, N.1    Nishikimi, T.2    Yoshihara, F.3
  • 6
    • 0031613014 scopus 로고    scopus 로고
    • Adrenomedullin: A possible autocrine or paracrine inhibitor of hypertrophy of cardiomyocytes
    • Tsuruda T, Johji K, Kitamura K, et al. Adrenomedullin: a possible autocrine or paracrine inhibitor of hypertrophy of cardiomyocytes. Hypertension. 1998;31:505-510.
    • (1998) Hypertension , vol.31 , pp. 505-510
    • Tsuruda, T.1    Johji, K.2    Kitamura, K.3
  • 7
    • 0032846084 scopus 로고    scopus 로고
    • An autocrine or a paracrine role of adrenomedullin in modulating cardiac fibroblast growth
    • Tsuruda T, Johji K, Kitamura K, et al. An autocrine or a paracrine role of adrenomedullin in modulating cardiac fibroblast growth. Cardiovasc Res. 1999;43:958-967.
    • (1999) Cardiovasc Res , vol.43 , pp. 958-967
    • Tsuruda, T.1    Johji, K.2    Kitamura, K.3
  • 8
    • 0037796698 scopus 로고    scopus 로고
    • Hemodynamic, renal, and hormonal effects of adrenomedullin infusion in patients with congestive heart failure
    • Nagaya N, Satoh T, Nishikimi T, et al. Hemodynamic, renal, and hormonal effects of adrenomedullin infusion in patients with congestive heart failure. Circulation. 2000;101:498-503.
    • (2000) Circulation , vol.101 , pp. 498-503
    • Nagaya, N.1    Satoh, T.2    Nishikimi, T.3
  • 9
    • 0035816724 scopus 로고    scopus 로고
    • Adrenomedullin induces endothelium-dependent vasorelaxation via the phosphatidylinositol 3-kinase/Akt-dependent pathway in rat aorta
    • Nishimatsu H, Suzuki E, Nagata D, et al. Adrenomedullin induces endothelium-dependent vasorelaxation via the phosphatidylinositol 3-kinase/Akt-dependent pathway in rat aorta. Circ Res. 2001;89:63-70.
    • (2001) Circ Res , vol.89 , pp. 63-70
    • Nishimatsu, H.1    Suzuki, E.2    Nagata, D.3
  • 10
    • 0035902451 scopus 로고    scopus 로고
    • Akt activation preserves cardiac function and prevents injury after transient cardiac ischemia in vivo
    • Matsui T, Tao J, del Monte F, et al. Akt activation preserves cardiac function and prevents injury after transient cardiac ischemia in vivo. Circulation. 2001;104:330-335.
    • (2001) Circulation , vol.104 , pp. 330-335
    • Matsui, T.1    Tao, J.2    Del Monte, F.3
  • 11
    • 0032923160 scopus 로고    scopus 로고
    • Cardiovascular and renal effects of adrenomedullin in rats with heart failure
    • Nagaya N, Nishikimi T, Horio T, et al. Cardiovascular and renal effects of adrenomedullin in rats with heart failure. Am J Physiol. 1999;276:R213-R218.
    • (1999) Am J Physiol , vol.276
    • Nagaya, N.1    Nishikimi, T.2    Horio, T.3
  • 12
    • 0037177142 scopus 로고    scopus 로고
    • Nitric oxide mediates the antiapoptotic effect of insulin in myocardial ischemia-reperfusion: The roles of PI3-kinase, Akt, and endothelial nitric oxide synthase phosphorylation
    • Gao F, Gao E, Yue TL, et al. Nitric oxide mediates the antiapoptotic effect of insulin in myocardial ischemia-reperfusion: the roles of PI3-kinase, Akt, and endothelial nitric oxide synthase phosphorylation. Circulation. 2002;105:1497-1502.
    • (2002) Circulation , vol.105 , pp. 1497-1502
    • Gao, F.1    Gao, E.2    Yue, T.L.3
  • 13
    • 0034625134 scopus 로고    scopus 로고
    • Endogenous tumor necrosis factor protects the adult cardiac myocyte against ischemic-induced apoptosis in a murine model of acute myocardial infarction
    • Kurrelmeyer KM, Michael LH, Baumgarten G, et al. Endogenous tumor necrosis factor protects the adult cardiac myocyte against ischemic-induced apoptosis in a murine model of acute myocardial infarction. Proc Natl Acad Sci U S A. 2000;97:5456-5461.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 5456-5461
    • Kurrelmeyer, K.M.1    Michael, L.H.2    Baumgarten, G.3
  • 14
    • 0032705566 scopus 로고    scopus 로고
    • Quantitative assessment of cardiac myocyte apoptosis in tissue sections using the fluorescence-based TUNEL technique enhanced with counterstains
    • Scarabelli TM, Knight RA, Rayment NB, et al. Quantitative assessment of cardiac myocyte apoptosis in tissue sections using the fluorescence-based TUNEL technique enhanced with counterstains. J Immunol Methods. 1999;228:23-28.
    • (1999) J Immunol Methods , vol.228 , pp. 23-28
    • Scarabelli, T.M.1    Knight, R.A.2    Rayment, N.B.3
  • 15
    • 0027967063 scopus 로고
    • Reperfusion injury induces apoptosis in rabbit cardiomyocytes
    • Gottlieb RA, Burleson KO, Kloner RA, et al. Reperfusion injury induces apoptosis in rabbit cardiomyocytes. J Clin Invest. 1994;94:1621-1628.
    • (1994) J Clin Invest , vol.94 , pp. 1621-1628
    • Gottlieb, R.A.1    Burleson, K.O.2    Kloner, R.A.3
  • 16
    • 0030819138 scopus 로고    scopus 로고
    • Myocyte apoptosis during acute myocardial infarction in the mouse localizes to hypoxic regions but occurs independently of p53
    • Bialik S, Geenen DL, Sasson IE, et al. Myocyte apoptosis during acute myocardial infarction in the mouse localizes to hypoxic regions but occurs independently of p53. J Clin Invest. 1997;100:1363-1372.
    • (1997) J Clin Invest , vol.100 , pp. 1363-1372
    • Bialik, S.1    Geenen, D.L.2    Sasson, I.E.3
  • 17
    • 0030974608 scopus 로고    scopus 로고
    • Adrenomedullin as an autocrine/paracrine apoptosis survival factor for rat endothelial cells
    • Kato H, Shichiri M, Marumo F, et al. Adrenomedullin as an autocrine/paracrine apoptosis survival factor for rat endothelial cells. Endocrinology. 1997;138:2615-2620.
    • (1997) Endocrinology , vol.138 , pp. 2615-2620
    • Kato, H.1    Shichiri, M.2    Marumo, F.3
  • 18
    • 0033854559 scopus 로고    scopus 로고
    • Adrenomedullin and nitric oxide inhibit human endothelial cell apoptosis via a cyclic GMP-independent mechanism
    • Sata M, Kakoki M, Nagata D, et al. Adrenomedullin and nitric oxide inhibit human endothelial cell apoptosis via a cyclic GMP-independent mechanism. Hypertension. 2000;36:83-88.
    • (2000) Hypertension , vol.36 , pp. 83-88
    • Sata, M.1    Kakoki, M.2    Nagata, D.3
  • 19
    • 0029799092 scopus 로고    scopus 로고
    • Apoptosis in the heart
    • Colucci WS. Apoptosis in the heart. N Engl J Med. 1996;335:1224-1226.
    • (1996) N Engl J Med , vol.335 , pp. 1224-1226
    • Colucci, W.S.1
  • 20
    • 0035970539 scopus 로고    scopus 로고
    • Reperfusion-activated Akt kinase prevent apoptosis in transgenic mouse hearts overexpressing insulin-like growth factor-1
    • Yamashita K, Kajstura J, Discher DJ, et al. Reperfusion-activated Akt kinase prevent apoptosis in transgenic mouse hearts overexpressing insulin-like growth factor-1. Circ Res. 2001;88:609-614.
    • (2001) Circ Res , vol.88 , pp. 609-614
    • Yamashita, K.1    Kajstura, J.2    Discher, D.J.3
  • 21
    • 0030907987 scopus 로고    scopus 로고
    • PI3K: Downstream AKTion blocks apoptosis
    • Franke TF, Kaplan DR, Cantley LC, et al. PI3K: downstream AKTion blocks apoptosis. Cell. 1997;88:435-437.
    • (1997) Cell , vol.88 , pp. 435-437
    • Franke, T.F.1    Kaplan, D.R.2    Cantley, L.C.3
  • 22
    • 7144227966 scopus 로고    scopus 로고
    • Increased plasma adrenomedullin levels in patients with acute myocardial infarction in proportion to the clinical severity
    • Miyao Y, Nishikimi T, Goto Y, et al. Increased plasma adrenomedullin levels in patients with acute myocardial infarction in proportion to the clinical severity. Heart. 1998;79:39-44.
    • (1998) Heart , vol.79 , pp. 39-44
    • Miyao, Y.1    Nishikimi, T.2    Goto, Y.3
  • 23
    • 0032570292 scopus 로고    scopus 로고
    • Attenuation of ischemia/reperfusion injury in rats by caspase inhibitor
    • Yaoita H, Ogawa K, Maehara K, et al. Attenuation of ischemia/reperfusion injury in rats by caspase inhibitor. Circulation. 1998;97:276-281.
    • (1998) Circulation , vol.97 , pp. 276-281
    • Yaoita, H.1    Ogawa, K.2    Maehara, K.3
  • 24
    • 0032516036 scopus 로고    scopus 로고
    • Overexpression of human copper, zinc-superoxide dismutase (SODI) prevents postischemic injury
    • Wang P, Chen H, Qin H, et al. Overexpression of human copper, zinc-superoxide dismutase (SODI) prevents postischemic injury. Proc Natl Acad Sci U S A. 1998;95:4556-4560.
    • (1998) Proc Natl Acad Sci U S A , vol.95 , pp. 4556-4560
    • Wang, P.1    Chen, H.2    Qin, H.3
  • 25
    • 0036233597 scopus 로고    scopus 로고
    • Intravenous adrenomedullin in myocardial function and energy metabolism in patients after myocardial infarction
    • Nagaya N, Goto Y, Satoh T, et al. Intravenous adrenomedullin in myocardial function and energy metabolism in patients after myocardial infarction. J Cardiovasc Pharmacol. 2002;39:754-760.
    • (2002) J Cardiovasc Pharmacol , vol.39 , pp. 754-760
    • Nagaya, N.1    Goto, Y.2    Satoh, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.