Adrenomedullin in the gastrointestinal tract. Distribution and gene expression in rat and augmented gastric adrenomedullin after fasting

Journal of Gastroenterology

Volumn 33, Issue 6, 1998, Pages 828-834

  Sakata, Junichiro ^a   Asada, Yujiro ^a   Shimokubo, Toru ^a   Kitani, Michitaka ^a   Inatsu, Haruhiko ^a   Kitamura, Kazuo ^a   Kangawa, Kenji ^b   Matsuo, Hisayuki ^b   Sumiyoshi, Akinobu ^a   Eto, Tanenao ^a  

^a UNIVERSITY OF MIYAZAKI   (Japan)

^b NATIONAL CEREBRAL AND CARDIOVASCULAR CENTER   (Japan)

Author keywords

Adrenomedullin; Bioactive peptide; Distribution in gastrointestinal tract; Endocrine cell; Fasting; Vasodilating activity

Indexed keywords

ADRENOMEDULLIN; MESSENGER RNA; VASODILATOR AGENT;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CECUM; COLON; CONTROLLED STUDY; DIET RESTRICTION; DUODENUM; ENDOCRINE CELL; ENDOCRINE SYSTEM; GASTROINTESTINAL TRACT; GENE EXPRESSION; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; ILEUM; IMMUNOHISTOCHEMISTRY; JEJUNUM; MALE; NONHUMAN; NORTHERN BLOTTING; PRIORITY JOURNAL; RADIOIMMUNOASSAY; RAT; STOMACH; STOMACH BLOOD FLOW; STOMACH MUCOSA; TIME; TISSUE DISTRIBUTION;

ADRENOMEDULLIN; ANIMALS; CULTURE TECHNIQUES; DIGESTIVE PHYSIOLOGY; FASTING; GASTRIC MUCOSA; GENE EXPRESSION; IMMUNOHISTOCHEMISTRY; INTESTINAL MUCOSA; MALE; PEPTIDES; RATS; RATS, SPRAGUE-DAWLEY; REFERENCE VALUES; RNA, MESSENGER;

EID: 0032466173     PISSN: 09441174     EISSN: None     Source Type: Journal    
DOI: 10.1007/s005350050183     Document Type: Article

References (36)

1. Kitamura K, Kangawa K, Eto T, et al. Isolation and characterization of peptides which act on rat platelets from a pheochromocytoma. Biochem Biophys Res Commun 1992; 185:134-141.
2. Kitamura K, Sakata J, Eto T, et al. Cloning and characterization of cDNA encoding a precursor for human adrenomedullin. Biochem Biophys Res Commun 1993;194:720-725.
3. Sakata J, Shimokubo T, Eto T, et al. Molecular cloning and biological activities of rat adrenomedullin, a hypotensive peptide. Biochem Biophys Res Commun 1993;195:921-927.
4. Nuki C, Kawasaki H, Eto T, et al. A vasodilator effect of adrenomedullin and calcitonin gene related peptide receptors in rat mesenteric vascular beds. Biochem Biophys Res Commun 1993;196:245-251.
5. Sakata J, Shimokubo T, Eto T, et al. Distribution and characterization of immunoreactive rat adrenomedullin in tissue and plasma. FEBS Lett 1994;352:105-108.
6. Ichiki Y, Kitamura K, Eto T, et al. Distribution and characterization of immunoreactive adrenomedullin in human tissue and plasma. FEBS Lett 1994;338:6-10.
7. Ishiyama Y, Kitamura K, Eto T, et al. Hemodynamic change of a novel hypotensive rat peptide, human adrenomedullin in rats. Eur J Pharmacol 1993;241:271-274.
8. Ishiyama Y, Sakata J, Eto T, et al. Hemodynamic responses to rat adrenomedullin in anaesthetized spontaneously hypertensive rats. Clin Exp Pharmacol Physiol 1995;22:614-618.
9. Ishizaka Y, Ishizaka Y, Eto T, et al. Adrenomedullin stimulates cyclic AMP formation in rat vascular smooth muscle cells. Biochem Biophys Res Commun 1994;200:642-646.
10. Eguchi S, Hirata Y, Maruno F, et al. Specific receptor for adrenomedullin in cultured rat vascular smooth muscle cells. FEBS Lett 1994;340:226-230.
11. 125I-containing acylating agent. Biochem J 1973;133:529-539.
12. Chomczynski P, Sacchi N. Single step method of RNA isolation by acid guanidium-thiocyanate-phenol-chloroform extraction. Anal Biochem 1987;162:156-159.
13. + RNA. In: Berger SL, Kimmel AR (eds) Methods in enzymology 152. Guide to molecular cloning techniques. London: Academic, 1987:254-261.
14. Sambrook J, Fritsch EF, Maniatis T. Molecular cloning a laboratory manual. 2nd ed. New York: Cold Spring Harbour Laboratories, 1989:7.43-7.50.
15. Sakata J, Uyeda K. Bovine heart fructose-6-phosphate 2-kinase/ fructose-2,6-bisphosphatase: Complete amino acid sequence and localization of phosphorylation sites. Proc Natl Acad Sci USA 1990;87:4951-4955.
16. Feinberg AP, Vogelstein B. A technique for radiolabeling DNA restriction endonuclease fragments to high specific activity. Anal Biochem 1983;132:6-13.
17. Tso JY, Sun XH, Wu R, et al. Isolation and characterization of rat and human glyceraldehyde-3-phosphate dehydrogenase cDNAs: Genomic complexity and molecular evolution of the gene. Nucleic Acids Res 1985;13:2485-2502.
18. Kitamura K, Kangawa K, Eto T, et al. Complete amino acid sequence of porcine adrenomedullin and cloning of cDNA encoding its precursor. FEBS Lett 1994;338:6-10.
19. O'Connor DT, Pamer RJ, Deftos LJ. Choromogranin A: Studies in the endocrine system. Trans Assoc Am Physicians 1984;97:242-250.
20. Wilson BS, Lloyd RV. Detection of chromogranin in neuroendocrine cells with a monoclonal antibody. Am J Pathol 1984; 115:458-468.
21. Solcia E, Capella C, Sessa F. Endocrine cells of the digestive system. In: Johnson LR (ed) Physiology of the gastrointestinal tract. 2nd ed. New York: Raven, 1987:111-129.
22. Delellis RA, Dayal Y. Neuroendocrine system. In: Sternberg SS (ed) Histology for pathologists. New York: Raven, 1992:347-362.
23. Washimine H, Asada Y, Eto T, et al. Immunohistochemical identification of adrenomedullin in human, rat, and porcine tissue. Histochem. 1995;103:251-254.
24. Mulder H, Ahren B, Sundler F, et al. Adrenomedullin: Localization in the gastrointestinal tract and effects on insulin secretion. Regul Pept 1996;62:107-112.
25. Shimokubo T, Sakata J, Eto T, et al. Alterations in tissue concentration and gene expression of adrenomedullin in spontaneously hypertensive rats. Pathophysiology 1995;2:223-226.
26. Shimokubo T, Sakata J, Eto T, et al. Augmented adrenomedullin concentrations in right ventricle and plasma of experimental pulmonary hypertension. Life Sci 1995;57:1771-1779.
27. Shimokubo T, Sakata J, Eto T, et al. Adrenomedullin: Changes in circulating and cardiac tissue concentration in Dahl salt-sensitive rats on a high-salt diet. Clin Exp Hypertens 1996;18:949-961.
28. Taylor TV, Pullan BR, Torrance HB. Effect of fasting on mucosal blood flow in antrum and corpus of the stomach Eur Surg Res 1976;8:227-235.
29. He H, Bessho H, Abe Y, et al. Effects of a synthetic rat adrenomedullin on regional hemodynamics in rats. Eur J pharmacol 1995;273:209-214.
30. Yanagizawa M, Kurihara H, Masaki T, et al. A novel potent vasoconstrictor peptide produced by vascular endothelial cells. Nature 1988;332:441-445.
31. Ota S, Hirata Y, Sugimoto T, et al. Endothelin-1 secretion from cultured rabbit gastric epithelial cells. J Cardiovasc Pharmacol 1991;17:S406-S407.
32. Whittle BJR, Esplugues JV. Induction of rat gastric damage by the endothelium-derived peptide, endothelin. Br J Pharmacol 1988;95:1011-1013.
33. Lazaratos S, Kashimura H, Goto K, et al. Gastric ulcer induced by submucosal injection of ET-1: Role of potent vasoconstriction and intraluminal acid. Am J Physiol 1993;265:G491-G498.
34. Rae GA, Calixto JB, D'Orleans Juste P. Effects and mechanisms of action of endothelin on non-vascular smooth muscle of the respiratory, gastrointestinal and urogenital tracts. Regul Pept 1995;55:1-46.
35. Kohno M, Kano H, Takeda T, et al. Inhibition of endothelin production by adrenomedullin in vascular smooth muscle cells. Hypertension 1995;25:1185-1190.
36. Wu V, Sumii K, Walsh JH, et al. Regulation of rat antral gastrin and somatostatin gene expression during starvation and after refeeding. Gastroenterology 1991;101:1552-1558.