메뉴 건너뛰기




Volumn 76, Issue 1, 2009, Pages 81-90

Polyethylene glycosylated curcumin conjugate inhibits pancreatic cancer cell growth through inactivation of Jab1

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; CURCUMIN; GEMCITABINE; JUN ACTIVATION DOMAIN BINDING PROTEIN 1; POLYETHYLENE GLYCOL CONJUGATED CURCUMIN; UNCLASSIFIED DRUG;

EID: 67649876052     PISSN: 0026895X     EISSN: 15210111     Source Type: Journal    
DOI: 10.1124/mol.109.054551     Document Type: Article
Times cited : (108)

References (38)
  • 1
    • 0035794541 scopus 로고    scopus 로고
    • COP9 signalosome-specific phosphorylation targets p53 to degradation by the ubiquitin system
    • DOI 10.1093/emboj/20.7.1630
    • Bech-Otschir D, Kraft R, Huang X, Henklein P, Kapelari B, Pollmann C, and Dubiel W (2001) COP9 signalosome-specific phosphorylation targets p53 to degradation by the ubiquitin system. EMBO J 20:1630-1639. (Pubitemid 32299400)
    • (2001) EMBO Journal , vol.20 , Issue.7 , pp. 1630-1639
    • Bech-Otschir, D.1    Kraft, R.2    Huang, X.3    Henklein, P.4    Kapelari, B.5    Pollmann, C.6    Dubiel, W.7
  • 3
    • 20444402990 scopus 로고    scopus 로고
    • Risk factors for pancreatic adenocarcinoma: Are we ready for screening and surveillance?
    • Brand R and Mahr C (2005) Risk factors for pancreatic adenocarcinoma: are we ready for screening and surveillance? Curr Gastroenterol Rep 7:122-127. (Pubitemid 40796697)
    • (2005) Current Gastroenterology Reports , vol.7 , Issue.2 , pp. 122-127
    • Brand, R.1    Mahr, C.2
  • 5
    • 0344420226 scopus 로고    scopus 로고
    • Pharmacokinetic and biodistribution properties of poly(ethylene glycol)-protein conjugates
    • DOI 10.1016/S0169-409X(03)00108-X
    • Caliceti P and Veronese FM (2003) Pharmacokinetic and biodistribution properties of poly(ethylene glycol)-protein conjugates. Adv Drug Deliv Rev 55:1261-1277. (Pubitemid 37464561)
    • (2003) Advanced Drug Delivery Reviews , vol.55 , Issue.10 , pp. 1261-1277
    • Caliceti, P.1    Veronese, F.M.2
  • 6
    • 0036093865 scopus 로고    scopus 로고
    • Inflammation and the development of pancreatic cancer
    • Farrow B, Evers BM (2004) Inflammation and the development of pancreatic cancer. Surg Oncol Oxf 10:153-159.
    • (2004) Surg Oncol Oxf , vol.10 , pp. 153-159
    • Farrow, B.1    Evers, B.M.2
  • 8
    • 33750043187 scopus 로고    scopus 로고
    • Depletion of Jab1 inhibits proliferation of pancreatic cancer cell lines
    • DOI 10.1016/j.febslet.2006.09.042, PII S0014579306011525
    • Fukumoto A, Tomoda K, Yoneda-Kato N, Nakajima Y, and Kato JY (2006) Depletion of Jab1 inhibits proliferation of pancreatic cancer cell lines. FEBS Lett 580:5836-5844. (Pubitemid 44584281)
    • (2006) FEBS Letters , vol.580 , Issue.25 , pp. 5836-5844
    • Fukumoto, A.1    Tomoda, K.2    Yoneda-Kato, N.3    Nakajima, Y.4    Kato, J.-Y.5
  • 9
    • 54949145754 scopus 로고    scopus 로고
    • Multi-targeted therapy by curcumin: How spicy is it?
    • Goel A, Jhurani S, and Aggarwal BB (2008) Multi-targeted therapy by curcumin: how spicy is it? Mol Nutr Food Res 52:1010-1030.
    • (2008) Mol Nutr Food Res , vol.52 , pp. 1010-1030
    • Goel, A.1    Jhurani, S.2    Aggarwal, B.B.3
  • 10
    • 0030071043 scopus 로고    scopus 로고
    • Drug delivery systems: Water soluble taxol 2'-poly(ethylene glycol) ester prodrugs-design and in vivo effectiveness
    • DOI 10.1021/jm950475e
    • Greenwald RB, Gilbert CW, Pendri A, Conover CD, Xia J, and Martinez A (1996) Drug delivery systems: water soluble Taxol 2′-poly(ethylene glycol) ester prodrugs-design and in vivo effectiveness. J Med Chem 39:424-431. (Pubitemid 26037894)
    • (1996) Journal of Medicinal Chemistry , vol.39 , Issue.2 , pp. 424-431
    • Greenwald, R.B.1    Gilbert, C.W.2    Pendri, A.3    Conover, C.D.4    Xia, J.5    Martinez, A.6
  • 11
    • 0037428969 scopus 로고    scopus 로고
    • Effective drug delivery by PEGylated drug conjugates
    • DOI 10.1016/S0169-409X(02)00180-1, PII S0169409X02001801
    • Greenwald RB, Choe YH, McGuire J, and Conover CD (2003) Effective drug delivery by PEGylated drug conjugates. Adv Drug Deliv Rev 55:217-250. (Pubitemid 36135917)
    • (2003) Advanced Drug Delivery Reviews , vol.55 , Issue.2 , pp. 217-250
    • Greenwald, R.B.1    Choe, Y.H.2    McGuire, J.3    Conover, C.D.4
  • 12
    • 0037105505 scopus 로고    scopus 로고
    • Curcumin inhibits interleukin 8 production and enhances interleukin 8 receptor expression on the cell surface: Impact on human pancreatic carcinoma cell growth by autocrine regulation
    • DOI 10.1002/cncr.10812
    • Hidaka H, Ishiko T, Furuhashi T, Kamohara H, Suzuki S, Miyazaki M, Ikeda O, Mita S, Setoguchi T, and Ogawa M (2002) Curcumin inhibits interleukin 8 production and enhances interleukin 8 receptor expression on the cell surface: impact on human pancreatic carcinoma cell growth by autocrine regulation. Cancer 95: 1206-1214. (Pubitemid 35013053)
    • (2002) Cancer , vol.95 , Issue.6 , pp. 1206-1214
    • Hidaka, H.1    Ishiko, T.2    Furuhashi, T.3    Kamohara, H.4    Suzuki, S.5    Miyazaki, M.6    Ikeda, O.7    Mita, S.8    Setoguchi, T.9    Ogawa, M.10
  • 14
    • 0348227997 scopus 로고    scopus 로고
    • Loss of DPC4 expression and its correlation with clinicopathological parameters in pancreatic carcinoma
    • Hua Z, Zhang YC, Hu XM, and Jia ZG (2003) Loss of DPC4 expression and its correlation with clinicopathological parameters in pancreatic carcinoma. World J Gastroenterol 9:2764-2767. (Pubitemid 38054456)
    • (2003) World Journal of Gastroenterology , vol.9 , Issue.12 , pp. 2764-2767
    • Hua, Z.1    Zhang, Y.-C.2    Hu, X.-M.3    Jia, Z.-G.4
  • 15
    • 0001267714 scopus 로고    scopus 로고
    • Gemcitabine: A cytidine analogue active against solid tumors
    • Hui YF and Reitz J (1997) Gemcitabine: a cytidine analogue active against solid tumors. Am J Health Syst Pharm 154:162-170. (Pubitemid 27058210)
    • (1997) American Journal of Health-System Pharmacy , vol.54 , Issue.2 , pp. 162-170
    • Hui, Y.F.1    Reitz, J.2
  • 16
    • 84934444244 scopus 로고    scopus 로고
    • Clinical studies with curcumin
    • Hsu CH and Cheng AL (2007) Clinical studies with curcumin. Adv Exp Med Biol 595:471-480.
    • (2007) Adv Exp Med Biol , vol.595 , pp. 471-480
    • Hsu, C.H.1    Cheng, A.L.2
  • 18
    • 1542314268 scopus 로고    scopus 로고
    • Jab1/CSN5, a Component of the COP9 Signalosome, Regulates Transforming Growth Factor beta Signaling by Binding to Smad7 and Promoting Its Degradation
    • DOI 10.1128/MCB.24.6.2251-2262.2004
    • Kim BC, Lee HJ, Park SH, Lee SR, Karpova TS, McNally JG, Felici A, Lee DK, and Kim SJ (2004) Jab1/CSN5, a component of the COP9 signalosome, regulates transforming growth factor beta signaling by binding to Smad7 and promoting its degradation. Mol Cell Biol 24:2251-2262. (Pubitemid 38325982)
    • (2004) Molecular and Cellular Biology , vol.24 , Issue.6 , pp. 2251-2262
    • Kim, B.-C.1    Lee, H.-J.2    Park, S.H.3    Lee, S.R.4    Karpova, T.S.5    McNally, J.G.6    Felici, A.7    Lee, D.K.8    Kim, S.-J.9
  • 21
    • 34248573808 scopus 로고    scopus 로고
    • Curcumin potentiates antitumor activity of gemcitabine in an orthotopic model of pancreatic cancer through suppression of proliferation, angiogenesis, and inhibition of nuclear factor-κB-regulated gene products
    • DOI 10.1158/0008-5472.CAN-06-4257
    • Kunnumakkara AB, Guha S, Krishnan S, Diagaradjane P, Gelovani J, and Aggarwal BB (2007) Curcumin potentiates antitumor activity of gemcitabine in an orthotopic model of pancreatic cancer through suppression of proliferation, angiogenesis, and inhibition of nuclear factor-κB-regulated gene products. Cancer Res 67:3853-3861. (Pubitemid 46762173)
    • (2007) Cancer Research , vol.67 , Issue.8 , pp. 3853-3861
    • Kunnumakkara, A.B.1    Guha, S.2    Krishnan, S.3    Diagaradjane, P.4    Gelovani, J.5    Aggarwal, B.B.6
  • 22
    • 31544471349 scopus 로고    scopus 로고
    • Curcumin synergistically potentiates the growth inhibitory and pro-apoptotic effects of celecoxib in pancreatic adenocarcinoma cells
    • DOI 10.1016/S0753-3322(05)80045-9, PII S0753332205800459
    • Lev-Ari S, Zinger H, Kazanov D, Yona D, Ben-Yosef R, Starr A, Figer A, and Arber N (2005) Curcumin synergistically potentiates the growth inhibitory and proapoptotic effects of celecoxib in pancreatic adenocarcinoma cells. Biomed Pharmacother 59 (Suppl 2):S276-S280. (Pubitemid 43303888)
    • (2005) Biomedicine and Pharmacotherapy , vol.59 , Issue.SUPPL. 2
    • Lev-Ari, S.1    Zinger, H.2    Kazanov, D.3    Yona, D.4    Ben-Yosef, R.5    Starr, A.6    Figer, A.7    Arber, N.8
  • 23
    • 7644223910 scopus 로고    scopus 로고
    • Nuclear factor-kappaB and IkappaB are constitutively active in human pancreatic cells, and their down-regulation by curcumin (Diferuloylmethane) is associated with the suppression of proliferation and the induction of apoptosis
    • DOI 10.1002/cncr.20605
    • Li L, Aggarwal BB, Shishodia S, Abbruzzese J, and Kurzrock R (2004) Nuclear factor-kappaB and IkappaB kinase are constitutively active in human pancreatic cells, and their down-regulation by curcumin (diferuloylmethane) is associated with the suppression of proliferation and the induction of apoptosis. Cancer 101: 2351-2362. (Pubitemid 39458693)
    • (2004) Cancer , vol.101 , Issue.10 , pp. 2351-2362
    • Li, L.1    Aggarwal, B.B.2    Shishodia, S.3    Abbruzzese, J.4    Kurzrock, R.5
  • 24
    • 24644508916 scopus 로고    scopus 로고
    • Liposome-encapsulated curcumin: In vitro and in vivo effects on proliferation, apoptosis, signaling, and angiogenesis
    • DOI 10.1002/cncr.21300
    • Li L, Braiteh FS, and Kurzrock R (2005) Liposome-encapsulated curcumin: in vitro and in vivo effects on proliferation, apoptosis, signaling, and angiogenesis. Cancer 104:1322-1331. (Pubitemid 41282806)
    • (2005) Cancer , vol.104 , Issue.6 , pp. 1322-1331
    • Li, L.1    Braiteh, F.S.2    Kurzrock, R.3
  • 25
    • 0034993240 scopus 로고    scopus 로고
    • The enhanced permeability and retention (EPR) effect in tumor vasculature: The key role of tumor-selective macromolecular drug targeting
    • DOI 10.1016/S0065-2571(00)00013-3, PII S0065257100000133
    • Maeda H (2001) The enhanced permeability and retention (EPR) effect in tumor vasculature: the key role of tumor-selective macromolecular drug targeting. Adv Enzyme Regul 41:189-207. (Pubitemid 32520323)
    • (2001) Advances in Enzyme Regulation , vol.41 , pp. 189-207
    • Maeda, H.1
  • 26
    • 33644901007 scopus 로고    scopus 로고
    • Multiple biological activities of curcumin: A short review
    • Maheshwari RK, Singh AK, Gaddipati J, and Srimal RC (2006) Multiple biological activities of curcumin: a short review. Life Sci 78:2081-2087.
    • (2006) Life Sci , vol.78 , pp. 2081-2087
    • Maheshwari, R.K.1    Singh, A.K.2    Gaddipati, J.3    Srimal, R.C.4
  • 28
    • 0038686677 scopus 로고    scopus 로고
    • Evidence for a physical association of the COP9 signalosome, the proteasome, and specific SCF E3 ligases in vivo
    • DOI 10.1016/S0960-9822(03)00439-1
    • Peng Z, Shen Y, Feng S, Wang X, Chitteti BN, Vierstra RD, and Deng XW (2003) Evidence for a physical association of the COP9 signalosome, the proteasome, and specific SCF E3 ligases in vivo. Curr Biol 13:R504-R505. (Pubitemid 36815244)
    • (2003) Current Biology , vol.13 , Issue.13
    • Peng, Z.1    Shen, Y.2    Feng, S.3    Wang, X.4    Chitteti, B.N.5    Vierstra, R.D.6    Deng, X.W.7
  • 31
    • 0035675964 scopus 로고    scopus 로고
    • kip1 and poor prognosis in epithelial ovarian tumors
    • Sui L, Dong Y, Ohno M, Watanabe Y, Sugimoto K, Tai Y, and Tokuda M (2001) Jab1 expression is associated with inverse expression of p27(kip1) and poor prognosis in epithelial ovarian tumors. Clin Cancer Res 7:4130-4135. (Pubitemid 34044637)
    • (2001) Clinical Cancer Research , vol.7 , Issue.12 , pp. 4130-4135
    • Sui, L.1    Dong, Y.2    Ohno, M.3    Watanabe, Y.4    Sugimoto, K.5    Tai, Y.6    Tokuda, M.7
  • 32
    • 0037195929 scopus 로고    scopus 로고
    • Inositol 1,3,4-trisphosphate 5/6-kinase associates with the COP9 signalosome by binding to CSN1
    • DOI 10.1074/jbc.M208709200
    • Sun Y, Wilson MP, and Majerus PW (2002) Inositol 1,3,4-trisphosphate 5/6-kinase associates with the COP9 signalosome by binding to CSN1. J Biol Chem 277: 45759-45764. (Pubitemid 35417552)
    • (2002) Journal of Biological Chemistry , vol.277 , Issue.48 , pp. 45759-45764
    • Sun, Y.1    Wilson, M.P.2    Majerus, P.W.3
  • 33
    • 0033545636 scopus 로고    scopus 로고
    • Degradation of the cyclin-dependent-kinase inhibitor p27(Kip1) is instigated by Jab1
    • DOI 10.1038/18230
    • Tomoda K, Kubota Y, and Kato J (1999) Degradation of the cyclin-dependent-kinase inhibitor p27Kip1 is instigated by Jab1. Nature 398:160-165. (Pubitemid 29135455)
    • (1999) Nature , vol.398 , Issue.6723 , pp. 160-165
    • Tomoda, K.1    Kubota, Y.2    Kato, J.-Y.3
  • 34
    • 0034682480 scopus 로고    scopus 로고
    • Site-specific chemical modification with polyethylene glycol of recombinant immunotoxin anti-Tac(Fv)-PE38 (LMB-2) improves antitumor activity and reduces animal toxicity and immunogenicity
    • DOI 10.1073/pnas.140210597
    • Tsutsumi Y, Onda M, Nagata S, Lee B, Kreitman RJ, and Pastan I (2000) Site-specific chemical modification with polyethylene glycol of recombinant immunotoxin anti-Tac(Fv)-PE38 (LMB-2) improves antitumor activity and reduces animal toxicity and immunogenicity. Proc Natl Acad Sci U S A 97:8548-8553. (Pubitemid 30639710)
    • (2000) Proceedings of the National Academy of Sciences of the United States of America , vol.97 , Issue.15 , pp. 8548-8553
    • Tsutsumi, Y.1    Onda, M.2    Nagata, S.3    Lee, B.4    Kreitman, R.J.5    Pastan, I.6
  • 36
    • 0036198412 scopus 로고    scopus 로고
    • Jab1 antagonizes TGF-β signaling by inducing Smad4 degradation
    • DOI 10.1093/embo-reports/kvf024
    • Wan M, Cao X, Wu Y, Bai S, Wu L, Shi X, Wang N, and Cao X (2002) Jab1 antagonizes TGF-β signaling by inducint Smad4 degradation. EMBO Reports 3:171-176. (Pubitemid 34213496)
    • (2002) EMBO Reports , vol.3 , Issue.2 , pp. 171-176
    • Wan, M.1    Cao, X.2    Wu, Y.3    Bai, S.4    Wu, L.5    Shi, X.6    Wang, N.7    Cao, X.8
  • 38
    • 33646877856 scopus 로고    scopus 로고
    • Notch-1 down-regulation by curcumin is associated with the inhibition of cell growth and the induction of apoptosis in pancreatic cancer cells
    • DOI 10.1002/cncr.21904
    • Wang Z, Zhang Y, Banerjee S, Li Y, and Sarkar FH (2006) Notch-1 down-regulation by curcumin is associated with the inhibition of cell growth and the induction of apoptosis in pancreatic cancer cells. Cancer 106:2503-2513. (Pubitemid 43787677)
    • (2006) Cancer , vol.106 , Issue.11 , pp. 2503-2513
    • Wang, Z.1    Zhang, Y.2    Banerjee, S.3    Li, Y.4    Sarkar, F.H.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.