Drug delivery systems: Water soluble taxol 2′-poly(ethylene glycol) ester prodrugs-design and in vivo effectiveness

Journal of Medicinal Chemistry

Volumn 39, Issue 2, 1996, Pages 424-431

  Greenwald, Richard B ^a   Gilbert, Carl W ^a   Pendri, Annapurna ^a   Conover, Charles D ^a   Xia, Jing ^a   Martinez, Anthony ^a  

^a Enzon Incorporated   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MACROGOL DERIVATIVE; PACLITAXEL DERIVATIVE; PRODRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; DRUG ADMINISTRATION; DRUG CYTOTOXICITY; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG EFFICACY; DRUG HALF LIFE; DRUG HYDROLYSIS; DRUG SOLUBILITY; DRUG TRANSPORT; FEMALE; LETHALITY; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PHARMACEUTICS; PHARMACOKINETICS;

ANIMALS; ANTINEOPLASTIC AGENTS; DRUG DELIVERY SYSTEMS; HALF-LIFE; HYDROLYSIS; LETHAL DOSE 50; LEUKEMIA L1210; LEUKEMIA P388; MAGNETIC RESONANCE SPECTROSCOPY; MICE; PACLITAXEL; POLYETHYLENE GLYCOLS; PRODRUGS; TUMOR CELLS, CULTURED;

EID: 0030071043     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm950475e     Document Type: Article

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