Protein kinase CK2 and protein kinase D are associated with the COP9 signalosome

EMBO Journal

Volumn 22, Issue 6, 2003, Pages 1302-1312

  Uhle, Stefan ^a   Medalia, Ohad ^b   Waldron, Richard ^a   Dumdey, Renate ^c   Henklein, Peter ^a   Bech Otschir, Dawadschargal ^a   Huang, Xiaohua ^a   Berse, Matthias ^a   Sperling, Joseph ^d   Schade, Rüdiger ^a   Dubiel, Wolfgang ^a  

^a HUMBOLDT UNIVERSITY   (Germany)

^b MAX PLANCK INSTITUTE OF BIOCHEMISTRY   (Germany)

^c UNIVERSITY OF CALIFORNIA   (United States)

^d WEIZMANN INSTITUTE OF SCIENCE   (Israel)

Author keywords

C Jun; COP9 signalosome; P53; Protein kinase CK2; Protein kinase D

Indexed keywords

CURCUMIN; EMODIN; PROTEIN KINASE; PROTEIN P53; RESVERATROL; STRESS ACTIVATED PROTEIN KINASE;

ARTICLE; COMPLEX FORMATION; ENZYME ACTIVITY; ENZYME DEGRADATION; ENZYME PURIFICATION; ENZYME SUBSTRATE; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; MAMMAL CELL; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN PHOSPHORYLATION; TARGET CELL;

ADENOSINE TRIPHOSPHATE; CASEIN KINASE II; CURCUMIN; DICHLORORIBOFURANOSYLBENZIMIDAZOLE; DNA-BINDING PROTEINS; EMODIN; ENZYME INHIBITORS; ERYTHROCYTES; HELA CELLS; HUMANS; MULTIPROTEIN COMPLEXES; PEPTIDE HYDROLASES; PHOSPHORYLATION; PROTEIN KINASE C; PROTEIN SUBUNITS; PROTEIN-SERINE-THREONINE KINASES; PROTEINS; PROTO-ONCOGENE PROTEINS C-JUN; RECOMBINANT PROTEINS; SIGNAL TRANSDUCTION; STILBENES; SUBSTRATE SPECIFICITY; TUMOR SUPPRESSOR PROTEIN P53; UBIQUITINS;

MAMMALIA;

EID: 0344837349     PISSN: 02614189     EISSN: None     Source Type: Journal    
DOI: 10.1093/emboj/cdg127     Document Type: Article

References (42)

1. Ahmed, K., Gerber, D.A. and Cochet, C. (2002) Joining the cell survival squad: an emerging role for protein kinase CK2. Trends Cell Biol., 12, 226-230.
2. Battistutta, R., Sarno, S., De Moliner, E., Papinutto, E., Zanotti, G. and Pinna, L.A. (2000) The replacement of ATP by the competitive inhibitor emodin induces conformational modifications in the catalytic site of protein kinase CK2. J. Biol. Chem., 275, 29618-29622.
3. Bech-Otschir, D., Kraft, R., Huang, X., Henklein, P., Kapelari, B., Pollmann, C. and Dubiel, W. (2001) COP9 signalosome-specific phosphorylation targets p53 to degradation by the ubiquitin system. EMBO J., 20, 1630-1639.
4. Bech-Otschir, D., Seeger, M. and Dubiel, W. (2002) The COP9 signalosome: at the interface between signal transduction and ubiquitin-dependent proteolysis. J. Cell Sci., 115, 467-473.
5. Cohen, H., Azriel, A., Cohen, T., Meraro, D., Hashmueli, S., Bech-Otschir, D., Kraft, R., Dubiel, W. and Levi, B.Z. (2000) Interaction between interferon consensus sequence-binding protein and COP9/signalosome subunit CSN2 (Trip15). A possible link between interferon regulatory factor signaling and the COP9/signalosome. J. Biol. Chem., 275, 39081-39089.
6. Cope, G.A., Suh, G.S., Aravind, L., Schwarz, S.E., Zipursky, S.L., Koonin, E.V. and Deshaies, R.J. (2002) Role of predicted metalloprotease motif of Jab1/Csn5 in cleavage of Nedd8 from Cull. Science, 298, 608-611.
7. Deng, X.-W. et al. (2000) Unified nomenclature for the COP9 signalosome and its subunits: an essential regulator of development. Trends Genet., 16, 202-203.
8. Faust, M. and Montenarh, M. (2000) Subcellular localization of protein kinase CK2. Cell Tissue Res., 301, 329-340.
9. Ferrell, K., Wilkinson, C.R.M., Dubiel, W. and Gordon, C. (2000) Regulatory subunit interactions of the 26S proteasome, a complex problem. Trends Biochem. Sci., 25, 83-88.
10. Freilich, S., Oron, E., Kapp, Y., Nevo-Caspi, Y., Orgad, S., Segal, D. and Chamovitz, D.A. (1999) The COP9 signalosome is essential for development of Drosophila melanogaster. Curr. Biol., 9, 1187-1190.
11. Gebeyehu, G., Rao, P.Y., SooChan, P., Simms, D.A. and Klevan, L. (1987) Novel biotinylated nucleotide analogs for labeling and colorimetric detection of DNA. Nucleic Acids Res., 15, 4513-4534.
12. Glickman, M.H., Rubin, D.M., Coux, O., Wefes, I., Pfeifer, G., Cjeka, Z., Baumeister, W., Fried, V.A. and Finley, D. (1998) A subcomplex of the proteasome regulatory particle required for ubiquitin-conjugate degradation and related to the COP9-signalosome and eIF3. Cell, 94, 615-623.
13. Guerra, B. and Issinger, O.-G. (1999) Protein kinase CK2 and its role in cellular proliferation, development and pathology. Electrophoresis, 20, 391-408.
14. Hardtke, Ch.S., Gohda, K., Osterlund, M.T., Oyama, T., Okada, K. and Deng, X.-W. (2000) HY5 stability and activity in Arabidopsis is regulated by phosphorylation in its COP1 binding domain. EMBO J., 19, 4997-5006.
15. Haworth, R.S. and Avkiran, M. (2001) Inhibition of protein kinase D by resveratrol. Biochem. Pharmacol., 62, 1647-1651.
16. Henke, W., Ferrell, K., Bech-Otschir, D., Seeger, M., Schade, R., Jungblut, P., Naumann, M. and Dubiel, W. (1999) Comparison of human COP9 signalsome and 26S proteasome lid. Mol. Biol. Rep., 26, 29-34.
17. Hjerrild, M., Milne, D., Dumaz, N., Hay, T., Issinger, O.-G. and Meek, D. (2001) Phosphorylation of murine double minute clone 2 (MDM2) protein at serine-267 by protein kinase CK2 in vitro and in cultured cells. Biochem. J., 355, 347-356.
18. Hurd, C. and Rozengurt, E. (2001) Protein kinase D is sufficient to suppress EGF-induced c-Jun Ser63 phosphorylation. Biochem. Biophys. Res. Commun., 282, 404-408.
19. Kapelari, B., Bech-Otschir, D., Hegerl, R., Schade, R., Dumdey, R. and Dubiel, W. (2000) Electron microscopy and subunit-subunit interaction studies reveal a first architecture of COP9 signalosome. J. Mol. Biol., 300, 1169-1178.
20. Karniol, B., Malec, P. and Chamovitz, D.A. (1999) Arabidopsis FUSCA5 encodes a novel phosphoprotein that is a component of the COP9 complex. Plant Cell, 11, 839-848.
21. Kawakami, T. et al. (2001) NEDD8 recruits E2-ubiquitin to SCF E3 ligase. EMBO J., 20, 4003-4012.
22. Lyapina, S. et al. (2001) Promotion of NEDD-CUL1 conjugate cleavage by COP9 signalosome. Science, 292, 1382-1385.
23. Musti, A.M., Treier, M. and Bohmann, D. (1997) Reduced ubiquitin-dependent degradation of c-Jun after phosphorylation by MAP kinases. Science, 275, 400-402.
24. Naumann, M., Bech-Otschir, D., Huang, X., Ferrell, K. and Dubiel, W. (1999) COP9 signalosome-directed c-Jun activation/stabilization is independent of JNK. J. Biol. Chem., 274, 35297-35300.
25. Osterlund, M.T., Hardtke, C.S., Wei, N. and Deng, X.-W. (2000) Targeted destabilization of HY5 during light-regulated development of Arabidopsis. Nature, 405, 462-466.
26. Poele, R.H., Okorokov, A.L. and Joel, S.P. (1999) RNA synthesis block by 5,6-dichloro-1-β-D-ribofuranosylbenzimidazole (DRB) triggers p53-dependent apoptosis in human colon carcinoma cells. Oncogene, 18, 5765-5772.
27. Pollmann, C., Huang, X., Mall, J., Bech-Otschir, D., Naumann, M. and Dubiel, W. (2001) The COP9 signalosome directs VEGF production in tumor cells. Cancer Res., 61, 8416-8421.
28. Schwechheimer, C. and Deng, X.-W. (2001) COP9 signalosome revisited: a novel mediator of protein degradation. Trends Cell Biol., 11, 420-425.
29. Schwechheimer, C., Serino, G., Callis, J., Crosby, W.L., Lyapina, S., Deshaies, R.J., Gray, W.M., Estelle, M. and Deng, X.-W. (2001) Interactions of the COP9 signalosome with the E3 ubiquitin ligase SCFTIRI in mediating auxin response. Science, 292, 1379-1382.
30. Schwechheimer, C., Serino, G. and Deng, X.-W. (2002) Multiple ubiquitin ligase-mediated processes require COP9 signalosome and AXR1 function. Plant Cell, 14, 2553-2563.
31. Seeger, M., Kraft, R., Ferrell, K., Bech-Otschir, D., Dumdey, R., Schade, R., Gordon, C., Naumann, M. and Dubiel, W. (1998) A novel protein complex involved in signal transduction possessing similarities to 26S proteasome subunits. FASEB J., 12, 469-478.
32. Slot, J.W. and Geuze, H.J. (1985) A new method of preparing gold probes for multiple-labeling cytochemistry. Eur. J. Cell Biol., 38, 87-93.
33. Sun, Y., Wilson, M.P. and Majerus, P.W. (2002) Inositol 1,3,4-trisphosphate associates with the COP9 signalosome by binding to CSN1. J. Biol. Chem., 277, 45759-45764.
34. Kip1 is instigated by Jab1. Nature, 398, 160-165.
35. Van Lint, J., Rykx, A., Maeda, Y., Vantus, T., Sturany, S., Malhotra, V., Vandenheede, J.R. and Seufferlein, T. (2002) Protein kinase D: an intracellular traffic regulator on the move. Trends Cell Biol., 12, 193-200.
36. Waldron, R.T., Rey, O., Iglesias, T., Tugal, T., Cantrell, D. and Rozengurt, E. (2001) Activation loop Ser744 and Ser748 in protein kinase D are transphosphorylated in vivo. J. Biol. Chem., 276, 32606-32615.
37. Wei, N. and Deng, X.W. (1999) Making sense of the COP9 signalosome. A regulatory protein complex conserved from Arabidopsis to human. Trends Genet., 15, 98-103.
38. Wei, N., Chamovitz, D.A. and Deng, X.W. (1994) Arabidopsis COP9 is a component of a novel signaling complex mediating light control of development. Cell, 78, 117-124.
39. Wei, N., Tsuge, T., Serino, G., Dohmae, N., Takio, K., Matsui, M. and Deng, X.W. (1998) The COP9 complex is conserved between plants and mammals and is related to the 26S proteasome regulatory complex. Curr. Biol., 8, 919-922.
40. Wilson, M.P., Sun, Y., Cao, L. and Majerus, P.W. (2001) Inositol 1,3,4-trisphosphate 5/6-kinase is a protein kinase that phosphorylates the transcription factors c-Jun and ATP-2. J. Biol. Chem., 276, 40998-41004.
41. 1-S phase progression via deneddylation of SCF Cull. Curr. Biol., 12, 667-672.
42. Zhou, C., Seibert, V., Geyer, R., Rhee, E., Lyapina, S., Cope, G., Deshaies, R.J. and Wolf, D.A. (2001) The fission yeast COP9/signalosome is involved in cullin modification by ubiquitin related Ned8p. BMC Biochem., 2, 7.