메뉴 건너뛰기




Volumn 171, Issue 3, 2004, Pages 1080-1084

Prognostic significance of endothelial Per-Arnt-Sim domain protein 1/hypoxia-inducible factor-2α expression in a subset of tumor associated macrophages in invasive bladder cancer

Author keywords

bHLH PAS factor HLF; Bladder; Carcinoma, transitional cell; Macrophages

Indexed keywords

CELL PROTEIN; ENDOTHELIAL PER ARNT SIM DOMAIN PROTEIN 1; HYPOXIA INDUCIBLE FACTOR 2ALPHA; UNCLASSIFIED DRUG;

EID: 12144287073     PISSN: 00225347     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.ju.0000110541.62972.08     Document Type: Article
Times cited : (26)

References (21)
  • 2
    • 0036187615 scopus 로고    scopus 로고
    • The role of tumour-associated macrophages in tumour progression: Implications for new anticancer therapies
    • Bingle, L., Brown, N. J. and Lewis, C. E.: The role of tumour-associated macrophages in tumour progression: implications for new anticancer therapies. J Pathol, 196: 254, 2002
    • (2002) J Pathol , vol.196 , pp. 254
    • Bingle, L.1    Brown, N.J.2    Lewis, C.E.3
  • 3
    • 0029842459 scopus 로고    scopus 로고
    • Oxygen sensing and molecular adaptation to hypoxia
    • Bunn, H. F. and Poyton, R. O.: Oxygen sensing and molecular adaptation to hypoxia. Physiol Rev, 76: 839, 1996
    • (1996) Physiol Rev , vol.76 , pp. 839
    • Bunn, H.F.1    Poyton, R.O.2
  • 4
    • 0030022252 scopus 로고    scopus 로고
    • Tumor oxygenation predicts for the likelihood of distant metastases in human soft tissue sarcoma
    • Brizel, D. M., Scully, S. P., Harrelson, J. M., Layfield, L. J., Bean, J. M., Prosnitz, L. R. et al: Tumor oxygenation predicts for the likelihood of distant metastases in human soft tissue sarcoma. Cancer Res, 56: 941, 1996
    • (1996) Cancer Res , vol.56 , pp. 941
    • Brizel, D.M.1    Scully, S.P.2    Harrelson, J.M.3    Layfield, L.J.4    Bean, J.M.5    Prosnitz, L.R.6
  • 5
    • 0027427588 scopus 로고
    • Characterization of hypoxia-inducible factor 1 and regulation of DNA binding activity by hypoxia
    • Wang, G. L. and Semenza, G. L.: Characterization of hypoxia-inducible factor 1 and regulation of DNA binding activity by hypoxia. J Biol Chem, 268: 21513, 1993
    • (1993) J Biol Chem , vol.268 , pp. 21513
    • Wang, G.L.1    Semenza, G.L.2
  • 6
    • 0031020884 scopus 로고    scopus 로고
    • Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells
    • Tian, H., McKnight, S. L. and Russell, D. W.: Endothelial PAS domain protein 1 (EPAS1), a transcription factor selectively expressed in endothelial cells. Genes Dev, 11: 72, 1997
    • (1997) Genes Dev , vol.11 , pp. 72
    • Tian, H.1    McKnight, S.L.2    Russell, D.W.3
  • 7
    • 0031823016 scopus 로고    scopus 로고
    • The molecular basis of the hypoxia response pathway: Tumour hypoxia as a therapy target
    • Blancher, C. and Harris, A. L.: The molecular basis of the hypoxia response pathway: tumour hypoxia as a therapy target. Cancer Metastasis Rev, 17: 187, 1998
    • (1998) Cancer Metastasis Rev , vol.17 , pp. 187
    • Blancher, C.1    Harris, A.L.2
  • 9
    • 0033870281 scopus 로고    scopus 로고
    • The expression and distribution of the hypoxia-inducible factors HIF-1alpha and HIF-2alpha in normal human tissues, cancers, and tumor-associated macrophages
    • Talks, K. L., Turley, H., Gatter, K. C., Maxwell, P. H., Pugh, C. W., Ratcliffe, P. J. et al: The expression and distribution of the hypoxia-inducible factors HIF-1alpha and HIF-2alpha in normal human tissues, cancers, and tumor-associated macrophages. Am J Pathol, 157: 411, 2000
    • (2000) Am J Pathol , vol.157 , pp. 411
    • Talks, K.L.1    Turley, H.2    Gatter, K.C.3    Maxwell, P.H.4    Pugh, C.W.5    Ratcliffe, P.J.6
  • 10
    • 0036190869 scopus 로고    scopus 로고
    • Hypoxia-induced, perinecrotic expression of endothelial Per-ARNT-Sim domain protein-1/hypoxia-inducible factor-2alpha correlates with tumor progression, vascularization, and focal macrophage infiltration in bladder cancer
    • Onita, T., Ji, P. G., Xuan, J. W., Sakai, H., Kanetake, H., Maxwell, P. H. et al: Hypoxia-induced, perinecrotic expression of endothelial Per-ARNT-Sim domain protein-1/hypoxia-inducible factor-2alpha correlates with tumor progression, vascularization, and focal macrophage infiltration in bladder cancer. Clin Cancer Res, 8: 471, 2002
    • (2002) Clin Cancer Res , vol.8 , pp. 471
    • Onita, T.1    Ji, P.G.2    Xuan, J.W.3    Sakai, H.4    Kanetake, H.5    Maxwell, P.H.6
  • 11
    • 0036493984 scopus 로고    scopus 로고
    • Relation of hypoxia-inducible factor-2 alpha (HIF-2 alpha) expression in tumor-infiltrative macrophages to tumor angiogenesis and the oxidative thymidine phosphorylase pathway in human breast cancer
    • Leek, R. D., Talks, K. L., Pezzella, F., Turley, H., Campo, L., Brown, N. S. et al: Relation of hypoxia-inducible factor-2 alpha (HIF-2 alpha) expression in tumor-infiltrative macrophages to tumor angiogenesis and the oxidative thymidine phosphorylase pathway in human breast cancer. Cancer Res, 62: 1326, 2002
    • (2002) Cancer Res , vol.62 , pp. 1326
    • Leek, R.D.1    Talks, K.L.2    Pezzella, F.3    Turley, H.4    Campo, L.5    Brown, N.S.6
  • 14
    • 0035871337 scopus 로고    scopus 로고
    • Regulation of vascular endothelial growth factor transcription by endothelial PAS domain protein 1 (EPAS1) and possible involvement of EPAS1 in the angiogenesis of renal cell carcinoma
    • Xia, G., Kageyama, Y., Hayashi, T., Kawakami, S., Yoshida, M. and Kihara, K.: Regulation of vascular endothelial growth factor transcription by endothelial PAS domain protein 1 (EPAS1) and possible involvement of EPAS1 in the angiogenesis of renal cell carcinoma. Cancer, 91: 1429, 2001
    • (2001) Cancer , vol.91 , pp. 1429
    • Xia, G.1    Kageyama, Y.2    Hayashi, T.3    Kawakami, S.4    Yoshida, M.5    Kihara, K.6
  • 15
    • 0037430057 scopus 로고    scopus 로고
    • Impaired delta Np63 expression associates with reduced beta-catenin and aggressive phenotypes of urothelial neoplasms
    • Koga, F., Kawakami, S., Kumagai, J., Takizawa, T., Ando, N., Arai, G. et al: Impaired delta Np63 expression associates with reduced beta-catenin and aggressive phenotypes of urothelial neoplasms. Br J Cancer, 88: 740, 2003
    • (2003) Br J Cancer , vol.88 , pp. 740
    • Koga, F.1    Kawakami, S.2    Kumagai, J.3    Takizawa, T.4    Ando, N.5    Arai, G.6
  • 16
    • 0030277564 scopus 로고    scopus 로고
    • Superficial bladder cancer: Decreasing the risk of recurrence
    • Grossman, H. B.: Superficial bladder cancer: decreasing the risk of recurrence. Oncology, 10: 1617, 1996
    • (1996) Oncology , vol.10 , pp. 1617
    • Grossman, H.B.1
  • 17
    • 0033949997 scopus 로고    scopus 로고
    • The natural history of bladder cancer. Implications for therapy
    • Lee, R. and Droller, M. J.: The natural history of bladder cancer. Implications for therapy. Urol Clin North Am, 27: 1, 2000
    • (2000) Urol Clin North Am , vol.27 , pp. 1
    • Lee, R.1    Droller, M.J.2
  • 18
    • 0026806968 scopus 로고
    • Metastatic bladder cancer. Natural history, clinical course, and consideration for treatment
    • Steinberg, G. D., Trump, D. L. and Cummings, K. B.: Metastatic bladder cancer. Natural history, clinical course, and consideration for treatment. Urol Clin North Am, 19: 735, 1992
    • (1992) Urol Clin North Am , vol.19 , pp. 735
    • Steinberg, G.D.1    Trump, D.L.2    Cummings, K.B.3
  • 19
    • 0033938697 scopus 로고    scopus 로고
    • Prognostic value of tumor-associated macrophage count in human bladder cancer
    • Hanada, T., Nakagawa, M., Emoto, A., Nomura, T., Nasu, N. and Nomura, Y.: Prognostic value of tumor-associated macrophage count in human bladder cancer. Int J Urol, 7: 263, 2000
    • (2000) Int J Urol , vol.7 , pp. 263
    • Hanada, T.1    Nakagawa, M.2    Emoto, A.3    Nomura, T.4    Nasu, N.5    Nomura, Y.6
  • 20
    • 0032407652 scopus 로고    scopus 로고
    • The invasive front of carcinomas. The most important area for tumour prognosis?
    • Bryne, M., Boysen, M., Alfsen, C. G., Abeler, V. M., Sudbo, J., Nesland, J. M. et al: The invasive front of carcinomas. The most important area for tumour prognosis? Anticancer Res, 18: 4757, 1998
    • (1998) Anticancer Res , vol.18 , pp. 4757
    • Bryne, M.1    Boysen, M.2    Alfsen, C.G.3    Abeler, V.M.4    Sudbo, J.5    Nesland, J.M.6
  • 21
    • 0034529914 scopus 로고    scopus 로고
    • Suppression of tumor growth through disruption of hypoxia-inducible transcription
    • Kung, A. L., Wang, S., Klco, J. M., Kaelin, W. G. and Livingston, D. M.: Suppression of tumor growth through disruption of hypoxia-inducible transcription. Nat Med, 6: 1335, 2000
    • (2000) Nat Med , vol.6 , pp. 1335
    • Kung, A.L.1    Wang, S.2    Klco, J.M.3    Kaelin, W.G.4    Livingston, D.M.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.