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Volumn 27, Issue 40, 2008, Pages 5354-5358

Hypoxia-inducible factor-2 regulates vascular tumorigenesis in mice

Author keywords

Cre loxP recombination; Hemangioma; Hypoxia inducible factor (HIF); Liver angiogenesis; Mouse model; Von Hippel Lindau (VHL) tumor suppressor

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 2ALPHA; VON HIPPEL LINDAU PROTEIN;

EID: 51649090078     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2008.160     Document Type: Article
Times cited : (130)

References (21)
  • 3
    • 33748714735 scopus 로고    scopus 로고
    • The transcriptional activator hypoxia inducible factor 2 (HIF-2/EPAS-1) regulates the oxygen-dependent expression of erythropoietin in cortical astrocytes
    • Chavez JC, Baranova O, Lin J, Pichiule P. (2006). The transcriptional activator hypoxia inducible factor 2 (HIF-2/EPAS-1) regulates the oxygen-dependent expression of erythropoietin in cortical astrocytes. J Neurosci 26: 9471-9481.
    • (2006) J Neurosci , vol.26 , pp. 9471-9481
    • Chavez, J.C.1    Baranova, O.2    Lin, J.3    Pichiule, P.4
  • 4
    • 1942498907 scopus 로고    scopus 로고
    • The Notch target genes Hey1 and Hey2 are required for embryonic vascular development
    • Fischer A, Schumacher N, Maier M, Sendtner M, Gessler M. (2004). The Notch target genes Hey1 and Hey2 are required for embryonic vascular development. Genes Dev 18: 901-911.
    • (2004) Genes Dev , vol.18 , pp. 901-911
    • Fischer, A.1    Schumacher, N.2    Maier, M.3    Sendtner, M.4    Gessler, M.5
  • 5
    • 0031870653 scopus 로고    scopus 로고
    • Up-regulation of vascular endothelial growth factor in stromal cells of hemangioblastomas is correlated with up-regulation of the transcription factor HRF/HIF-2alpha
    • Flamme I, Krieg M, Plate KH. (1998). Up-regulation of vascular endothelial growth factor in stromal cells of hemangioblastomas is correlated with up-regulation of the transcription factor HRF/HIF-2alpha. Am J Pathol 153: 25-29.
    • (1998) Am J Pathol , vol.153 , pp. 25-29
    • Flamme, I.1    Krieg, M.2    Plate, K.H.3
  • 8
    • 27644561755 scopus 로고    scopus 로고
    • Hypoxia requires notch signaling to maintain the undifferentiated cell state
    • Gustafsson MV, Zheng X, Pereira T, Gradin K, Jin S, Lundkvist J et al. (2005). Hypoxia requires notch signaling to maintain the undifferentiated cell state. Dev Cell 9: 617-628.
    • (2005) Dev Cell , vol.9 , pp. 617-628
    • Gustafsson, M.V.1    Zheng, X.2    Pereira, T.3    Gradin, K.4    Jin, S.5    Lundkvist, J.6
  • 9
    • 0035852668 scopus 로고    scopus 로고
    • Vascular tumors in livers with targeted inactivation of the von Hippel-Lindau tumor suppressor
    • Haase VH, Glickman JN, Socolovsky M, Jaenisch R. (2001). Vascular tumors in livers with targeted inactivation of the von Hippel-Lindau tumor suppressor. Proc Natl Acad Sci USA 98: 1583-1588.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 1583-1588
    • Haase, V.H.1    Glickman, J.N.2    Socolovsky, M.3    Jaenisch, R.4
  • 10
    • 33750630119 scopus 로고    scopus 로고
    • Recruitment of HIF-1alpha and HIF-2alpha to common target genes is differentially regulated in neuroblastoma: HIF-2alpha promotes an aggressive phenotype
    • Holmquist-Mengelbier L, Fredlund E, Lofstedt T, Noguera R, Navarro S, Nilsson H et al. (2006). Recruitment of HIF-1alpha and HIF-2alpha to common target genes is differentially regulated in neuroblastoma: HIF-2alpha promotes an aggressive phenotype. Cancer Cell 10: 413-423.
    • (2006) Cancer Cell , vol.10 , pp. 413-423
    • Holmquist-Mengelbier, L.1    Fredlund, E.2    Lofstedt, T.3    Noguera, R.4    Navarro, S.5    Nilsson, H.6
  • 11
    • 40949136438 scopus 로고    scopus 로고
    • The VHL tumor suppressor and HIF: Insights from genetic studies in mice
    • Kapitsinou PP, Haase VH. (2008). The VHL tumor suppressor and HIF: insights from genetic studies in mice. Cell Death Differ 15: 650-659.
    • (2008) Cell Death Differ , vol.15 , pp. 650-659
    • Kapitsinou, P.P.1    Haase, V.H.2
  • 13
    • 0026460626 scopus 로고
    • Case report: Multiple hepatic and pulmonary haemangioblastomas - a new manifestation of von Hippel-Lindau disease
    • McGrath FP, Gibney RG, Morris DC, Owen DA, Erb SR. (1992). Case report: multiple hepatic and pulmonary haemangioblastomas - a new manifestation of von Hippel-Lindau disease. Clin Radiol 45: 37-39.
    • (1992) Clin Radiol , vol.45 , pp. 37-39
    • McGrath, F.P.1    Gibney, R.G.2    Morris, D.C.3    Owen, D.A.4    Erb, S.R.5
  • 14
    • 34147124264 scopus 로고    scopus 로고
    • Hypoxia-inducible factor-2 (HIF-2) regulates hepatic erythropoietin in vivo
    • Rankin EB, Biju MP, Liu Q, Unger TL, Rha J, Johnson RS et al. (2007). Hypoxia-inducible factor-2 (HIF-2) regulates hepatic erythropoietin in vivo. J Clin Invest 117: 1068-1077.
    • (2007) J Clin Invest , vol.117 , pp. 1068-1077
    • Rankin, E.B.1    Biju, M.P.2    Liu, Q.3    Unger, T.L.4    Rha, J.5    Johnson, R.S.6
  • 15
    • 40949142209 scopus 로고    scopus 로고
    • The role of hypoxia-inducible factors in tumorigenesis
    • Rankin EB, Giaccia AJ. (2008). The role of hypoxia-inducible factors in tumorigenesis. Cell Death Differ 15: 678-685.
    • (2008) Cell Death Differ , vol.15 , pp. 678-685
    • Rankin, E.B.1    Giaccia, A.J.2
  • 16
    • 16244381736 scopus 로고    scopus 로고
    • Inactivation of the arylhydrocarbon receptor nuclear translocator (Arnt) suppresses von Hippel-Lindau disease-associated vascular tumors in mice
    • Rankin EB, Higgins DF, Walisser JA, Johnson RS, Bradfield CA, Haase VH. (2005). Inactivation of the arylhydrocarbon receptor nuclear translocator (Arnt) suppresses von Hippel-Lindau disease-associated vascular tumors in mice. Mol Cell Biol 25: 3163-3172.
    • (2005) Mol Cell Biol , vol.25 , pp. 3163-3172
    • Rankin, E.B.1    Higgins, D.F.2    Walisser, J.A.3    Johnson, R.S.4    Bradfield, C.A.5    Haase, V.H.6
  • 17
    • 20744445650 scopus 로고    scopus 로고
    • Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma
    • Raval RR, Lau KW, Tran MG, Sowter HM, Mandriota SJ, Li JL et al. (2005). Contrasting properties of hypoxia-inducible factor 1 (HIF-1) and HIF-2 in von Hippel-Lindau-associated renal cell carcinoma. Mol Cell Biol 25: 5675-5686.
    • (2005) Mol Cell Biol , vol.25 , pp. 5675-5686
    • Raval, R.R.1    Lau, K.W.2    Tran, M.G.3    Sowter, H.M.4    Mandriota, S.J.5    Li, J.L.6
  • 18
    • 34250351918 scopus 로고    scopus 로고
    • Functional implication of BMP4 expression on angiogenesis in malignant melanoma
    • Rothhammer T, Bataille F, Spruss T, Eissner G, Bosserhoff AK. (2007). Functional implication of BMP4 expression on angiogenesis in malignant melanoma. Oncogene 26: 4158-4170.
    • (2007) Oncogene , vol.26 , pp. 4158-4170
    • Rothhammer, T.1    Bataille, F.2    Spruss, T.3    Eissner, G.4    Bosserhoff, A.K.5
  • 19
    • 0030958304 scopus 로고    scopus 로고
    • von Hippel-Lindau gene deletion detected in the stromal cell component of a cerebellar hemangioblastoma associated with von Hippel-Lindau disease
    • Vortmeyer AO, Gnarra JR, Emmert-Buck MR, Katz D, Linehan WM, Oldfield EH et al. (1997). von Hippel-Lindau gene deletion detected in the stromal cell component of a cerebellar hemangioblastoma associated with von Hippel-Lindau disease. Hum Pathol 28: 540-543.
    • (1997) Hum Pathol , vol.28 , pp. 540-543
    • Vortmeyer, A.O.1    Gnarra, J.R.2    Emmert-Buck, M.R.3    Katz, D.4    Linehan, W.M.5    Oldfield, E.H.6
  • 20
    • 13544254639 scopus 로고    scopus 로고
    • Identification of transcriptional networks during liver regeneration
    • White P, Brestelli JE, Kaestner KH, Greenbaum LE. (2005). Identification of transcriptional networks during liver regeneration. J Biol Chem 280: 3715-3722.
    • (2005) J Biol Chem , vol.280 , pp. 3715-3722
    • White, P.1    Brestelli, J.E.2    Kaestner, K.H.3    Greenbaum, L.E.4
  • 21
    • 0036645091 scopus 로고    scopus 로고
    • Identification of cyclin D1 and other novel targets for the von Hippel-Lindau tumor suppressor gene by expression array analysis and investigation of cyclin D1 genotype as a modifier in von Hippel-Lindau disease
    • Zatyka M, Da Silva NF, Clifford SC, Morris MR, Wiesener MS, Eckardt KU et al. (2002). Identification of cyclin D1 and other novel targets for the von Hippel-Lindau tumor suppressor gene by expression array analysis and investigation of cyclin D1 genotype as a modifier in von Hippel-Lindau disease. Cancer Res 62: 3803-3811.
    • (2002) Cancer Res , vol.62 , pp. 3803-3811
    • Zatyka, M.1    Da Silva, N.F.2    Clifford, S.C.3    Morris, M.R.4    Wiesener, M.S.5    Eckardt, K.U.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.