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Volumn 27, Issue 1, 2008, Pages 44-54

A high-throughput screening for mammalian cell death effectors identifies the mitochondrial phosphate carrier as a regulator of cytochrome c release

Author keywords

Apoptosis; Atypical cell death; High throughput screening; Permeability transition; Phosphate carrier

Indexed keywords

CASPASE 9; COMPLEMENTARY DNA; CYTOCHROME C; FAS ANTIGEN; PHOSPHATE; SMALL INTERFERING RNA; VOLTAGE DEPENDENT ANION CHANNEL 1;

EID: 37849006735     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/sj.onc.1210600     Document Type: Article
Times cited : (82)

References (35)
  • 1
    • 0037449212 scopus 로고    scopus 로고
    • A high-throughput screen for single gene activities: Isolation of apoptosis inducers
    • Albayrak T, Grimm S. (2003). A high-throughput screen for single gene activities: isolation of apoptosis inducers. Biochem Biophys Res Commun 304: 772-776.
    • (2003) Biochem Biophys Res Commun , vol.304 , pp. 772-776
    • Albayrak, T.1    Grimm, S.2
  • 2
    • 0033611057 scopus 로고    scopus 로고
    • Adenine nucleotide translocase-1, a component of the permeability transition pore, can dominantly induce apoptosis
    • Bauer MK, Schubert A, Rocks O, Grimm S. (1999). Adenine nucleotide translocase-1, a component of the permeability transition pore, can dominantly induce apoptosis. J Cell Biol 147: 1493-1502.
    • (1999) J Cell Biol , vol.147 , pp. 1493-1502
    • Bauer, M.K.1    Schubert, A.2    Rocks, O.3    Grimm, S.4
  • 3
    • 33746912767 scopus 로고    scopus 로고
    • The permeability transition pore complex in cancer cell death
    • Brenner C, Grimm S. (2006). The permeability transition pore complex in cancer cell death. Oncogene 25: 4744-4756.
    • (2006) Oncogene , vol.25 , pp. 4744-4756
    • Brenner, C.1    Grimm, S.2
  • 4
    • 18244392443 scopus 로고    scopus 로고
    • Cell death independent of caspases: A review
    • Broker LE, Kruyt FA, Giaccone G. (2005). Cell death independent of caspases: a review. Clin Cancer Res 11: 3155-3162.
    • (2005) Clin Cancer Res , vol.11 , pp. 3155-3162
    • Broker, L.E.1    Kruyt, F.A.2    Giaccone, G.3
  • 6
    • 0036479049 scopus 로고    scopus 로고
    • Mitochondrial intermembrane junctional complexes and their involvement in cell death
    • Crompton M, Barksby E, Johnson N, Capano M. (2002). Mitochondrial intermembrane junctional complexes and their involvement in cell death. Biochimie 84: 143-152.
    • (2002) Biochimie , vol.84 , pp. 143-152
    • Crompton, M.1    Barksby, E.2    Johnson, N.3    Capano, M.4
  • 7
    • 2442609694 scopus 로고    scopus 로고
    • Mobilization of adenine nucleotide translocators as molecular bases of the biochemical threshold effect observed in mitochondrial diseases
    • Faustin B, Rossignol R, Rocher C, Benard G, Malgat M, Letellier T. (2004). Mobilization of adenine nucleotide translocators as molecular bases of the biochemical threshold effect observed in mitochondrial diseases. J Biol Chem 279: 20411-20421.
    • (2004) J Biol Chem , vol.279 , pp. 20411-20421
    • Faustin, B.1    Rossignol, R.2    Rocher, C.3    Benard, G.4    Malgat, M.5    Letellier, T.6
  • 9
    • 0032575752 scopus 로고    scopus 로고
    • Mitochondria and apoptosis
    • Green DR, Reed JC. (1998). Mitochondria and apoptosis. Science 281: 1309-1312.
    • (1998) Science , vol.281 , pp. 1309-1312
    • Green, D.R.1    Reed, J.C.2
  • 10
    • 1542320541 scopus 로고    scopus 로고
    • The art and design of genetic screens: Mammalian culture cells
    • Grimm S. (2004). The art and design of genetic screens: mammalian culture cells. Nat Rev Genet 5: 179-189.
    • (2004) Nat Rev Genet , vol.5 , pp. 179-189
    • Grimm, S.1
  • 11
    • 18944408104 scopus 로고    scopus 로고
    • Mitochondrial carrier homolog 2 is a target of tBID in cells signaled to die by tumor necrosis factor alpha
    • Grinberg M, Schwarz M, Zaltsman Y, Eini T, Niv H, Pietrokovski S et al. (2005). Mitochondrial carrier homolog 2 is a target of tBID in cells signaled to die by tumor necrosis factor alpha. Mol Cell Biol 25: 4579-4590.
    • (2005) Mol Cell Biol , vol.25 , pp. 4579-4590
    • Grinberg, M.1    Schwarz, M.2    Zaltsman, Y.3    Eini, T.4    Niv, H.5    Pietrokovski, S.6
  • 12
    • 4344707798 scopus 로고    scopus 로고
    • Mitochondrial permeability: Dual role for the ADP/ATP translocator? Nature
    • 1p following 983
    • Halestrap AP. (2004). Mitochondrial permeability: dual role for the ADP/ATP translocator? Nature 430: 1p following 983.
    • (2004) , vol.430
    • Halestrap, A.P.1
  • 13
    • 0037193474 scopus 로고    scopus 로고
    • DAP kinase and DRP-1 mediate membrane blebbing and the formation of autophagic vesicles during programmed cell death
    • Inbal B, Bialik S, Sabanay I, Shani G, Kimchi A. (2002). DAP kinase and DRP-1 mediate membrane blebbing and the formation of autophagic vesicles during programmed cell death. J Cell Biol 157: 455-468.
    • (2002) J Cell Biol , vol.157 , pp. 455-468
    • Inbal, B.1    Bialik, S.2    Sabanay, I.3    Shani, G.4    Kimchi, A.5
  • 14
    • 13944256602 scopus 로고    scopus 로고
    • Arsenic trioxide induces autophagic cell death in malignant glioma cells by upregulation of mitochondrial cell death protein BNIP3
    • Kanzawa T, Zhang L, Xiao L, Germano IM, Kondo Y, Kondo S. (2005). Arsenic trioxide induces autophagic cell death in malignant glioma cells by upregulation of mitochondrial cell death protein BNIP3. Oncogene 24: 980-991.
    • (2005) Oncogene , vol.24 , pp. 980-991
    • Kanzawa, T.1    Zhang, L.2    Xiao, L.3    Germano, I.M.4    Kondo, Y.5    Kondo, S.6
  • 16
    • 14744281338 scopus 로고    scopus 로고
    • Bcl-X(L) specifically activates Bak to induce swelling and restructuring of the endoplasmic reticulum
    • Klee M, Pimentel-Muiños FX. (2005). Bcl-X(L) specifically activates Bak to induce swelling and restructuring of the endoplasmic reticulum. J Cell Biol 168: 723-734.
    • (2005) J Cell Biol , vol.168 , pp. 723-734
    • Klee, M.1    Pimentel-Muiños, F.X.2
  • 17
    • 0037809232 scopus 로고    scopus 로고
    • Mitochondrial ATP synthasome. Cristae-enriched membranes and a multiwell detergent screening assay yield dispersed single complexes containing the ATP synthase and carriers for Pi and ADP/ATP
    • Ko YH, Delannoy M, Hullihen J, Chiu W, Pedersen PL. (2003). Mitochondrial ATP synthasome. Cristae-enriched membranes and a multiwell detergent screening assay yield dispersed single complexes containing the ATP synthase and carriers for Pi and ADP/ATP. J Biol Chem 278: 12305-12309.
    • (2003) J Biol Chem , vol.278 , pp. 12305-12309
    • Ko, Y.H.1    Delannoy, M.2    Hullihen, J.3    Chiu, W.4    Pedersen, P.L.5
  • 18
    • 0842307483 scopus 로고    scopus 로고
    • The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore
    • Kokoszka JE, Waymire KG, Levy SE, Sligh JE, Cai J, Jones DP et al. (2004). The ADP/ATP translocator is not essential for the mitochondrial permeability transition pore. Nature 427: 461-465.
    • (2004) Nature , vol.427 , pp. 461-465
    • Kokoszka, J.E.1    Waymire, K.G.2    Levy, S.E.3    Sligh, J.E.4    Cai, J.5    Jones, D.P.6
  • 19
    • 0038724274 scopus 로고    scopus 로고
    • Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways
    • Matsuda A, Suzuki Y, Honda G, Muramatsu S, Matsuzaki O, Nagano Y et al. (2003). Large-scale identification and characterization of human genes that activate NF-kappaB and MAPK signaling pathways. Oncogene 22: 3307-3318.
    • (2003) Oncogene , vol.22 , pp. 3307-3318
    • Matsuda, A.1    Suzuki, Y.2    Honda, G.3    Muramatsu, S.4    Matsuzaki, O.5    Nagano, Y.6
  • 20
    • 4344712684 scopus 로고    scopus 로고
    • Methods for monitoring autophagy
    • Mizushima N. (2004). Methods for monitoring autophagy. Int J Biochem Cell Biol 36: 2491-2502.
    • (2004) Int J Biochem Cell Biol , vol.36 , pp. 2491-2502
    • Mizushima, N.1
  • 21
    • 1242317666 scopus 로고    scopus 로고
    • The mitochondrial transporter family (SLC25): Physiological and pathological implications
    • Palmieri F. (2004). The mitochondrial transporter family (SLC25): physiological and pathological implications. Pflugers Arch 447: 689-709.
    • (2004) Pflugers Arch , vol.447 , pp. 689-709
    • Palmieri, F.1
  • 22
    • 0033452005 scopus 로고    scopus 로고
    • Regulated commitment of TNF receptor signaling: A molecular switch for death or activation
    • Pimentel-Muiños FX, Seed B. (1999). Regulated commitment of TNF receptor signaling: a molecular switch for death or activation. Immunity 11: 783-793.
    • (1999) Immunity , vol.11 , pp. 783-793
    • Pimentel-Muiños, F.X.1    Seed, B.2
  • 23
    • 33749003497 scopus 로고    scopus 로고
    • Cytopathic effects of the cytomegalovirus-encoded apoptosis inhibitory protein vMIA
    • Poncet D, Pauleau AL, Szabadkai G, Vozza A, Scholz SR, Le Bras M et al. (2006). Cytopathic effects of the cytomegalovirus-encoded apoptosis inhibitory protein vMIA. J Cell Biol 174: 985-996.
    • (2006) J Cell Biol , vol.174 , pp. 985-996
    • Poncet, D.1    Pauleau, A.L.2    Szabadkai, G.3    Vozza, A.4    Scholz, S.R.5    Le Bras, M.6
  • 24
    • 33644532847 scopus 로고    scopus 로고
    • Expression cloning screen for modifiers of amyloid precursor protein shedding
    • Schobel S, Neumann S, Seed B, Lichtenthaler SF. (2006). Expression cloning screen for modifiers of amyloid precursor protein shedding. Int J Dev Neurosci 24: 141-148.
    • (2006) Int J Dev Neurosci , vol.24 , pp. 141-148
    • Schobel, S.1    Neumann, S.2    Seed, B.3    Lichtenthaler, S.F.4
  • 25
    • 1542332908 scopus 로고    scopus 로고
    • Cyclophilin D, a component of the permeability transition-pore, is an apoptosis repressor
    • Schubert A, Grimm S. (2004). Cyclophilin D, a component of the permeability transition-pore, is an apoptosis repressor. Cancer Res 64: 85-93.
    • (2004) Cancer Res , vol.64 , pp. 85-93
    • Schubert, A.1    Grimm, S.2
  • 27
    • 0034687754 scopus 로고    scopus 로고
    • An alternative, nonapoptotic form of programmed cell death
    • Sperandio S, de Belle I, Bredesen DE. (2000). An alternative, nonapoptotic form of programmed cell death. Proc Natl Acad Sci USA 97: 14376-14381.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 14376-14381
    • Sperandio, S.1    de Belle, I.2    Bredesen, D.E.3
  • 29
    • 0036373335 scopus 로고    scopus 로고
    • Morphological and biochemical aspects of apoptosis, oncosis and necrosis
    • Van Cruchten S, Van Den Broeck W. (2002). Morphological and biochemical aspects of apoptosis, oncosis and necrosis. Anat Histol Embryol 31: 214-223.
    • (2002) Anat Histol Embryol , vol.31 , pp. 214-223
    • Van Cruchten, S.1    Van Den Broeck, W.2
  • 30
    • 7944225778 scopus 로고    scopus 로고
    • Dynamic evolution of the adenine nucleotide translocase interactome during chemotherapy-induced apoptosis
    • Verrier F, Deniaud A, Lebras M, Metivier D, Kroemer G, Mignotte B et al. (2004). Dynamic evolution of the adenine nucleotide translocase interactome during chemotherapy-induced apoptosis. Oncogene 23: 8049-8064.
    • (2004) Oncogene , vol.23 , pp. 8049-8064
    • Verrier, F.1    Deniaud, A.2    Lebras, M.3    Metivier, D.4    Kroemer, G.5    Mignotte, B.6
  • 31
    • 0037073733 scopus 로고    scopus 로고
    • The novel presenilin-1-associated protein is a proapoptotic mitochondrial protein
    • Xu X, Shi YC, Gao W, Mao G, Zhao G, Agrawal S et al. (2002). The novel presenilin-1-associated protein is a proapoptotic mitochondrial protein. J Biol Chem 277: 48913-48922.
    • (2002) J Biol Chem , vol.277 , pp. 48913-48922
    • Xu, X.1    Shi, Y.C.2    Gao, W.3    Mao, G.4    Zhao, G.5    Agrawal, S.6
  • 32
    • 0036857474 scopus 로고    scopus 로고
    • Met-HGF/SF signal transduction induces mimp, a novel mitochondrial carrier homologue, which leads to mitochondrial depolarization
    • Yerushalmi GM, Leibowitz-Amit R, Shaharabany M, Tsarfaty I. (2002). Met-HGF/SF signal transduction induces mimp, a novel mitochondrial carrier homologue, which leads to mitochondrial depolarization. Neoplasia 4: 510-522.
    • (2002) Neoplasia , vol.4 , pp. 510-522
    • Yerushalmi, G.M.1    Leibowitz-Amit, R.2    Shaharabany, M.3    Tsarfaty, I.4
  • 33
    • 1842636834 scopus 로고    scopus 로고
    • Adenine nucleotide translocase 3 (ANT-3) overexpression induces apoptosis in cultured cells
    • Zamora M, Granell M, Mampel T, Vinas O. (2004). Adenine nucleotide translocase 3 (ANT-3) overexpression induces apoptosis in cultured cells. FEBS Lett 563: 155-160.
    • (2004) FEBS Lett , vol.563 , pp. 155-160
    • Zamora, M.1    Granell, M.2    Mampel, T.3    Vinas, O.4
  • 34
    • 0035229427 scopus 로고    scopus 로고
    • The mitochondrion in apoptosis: How Pandora's box opens
    • Zamzami N, Kroemer G. (2001). The mitochondrion in apoptosis: how Pandora's box opens. Nat Rev Mol Cell Biol 2: 67-71.
    • (2001) Nat Rev Mol Cell Biol , vol.2 , pp. 67-71
    • Zamzami, N.1    Kroemer, G.2
  • 35
    • 11144300815 scopus 로고    scopus 로고
    • Mitochondrial permeability transitions: How many doors to the house?
    • Zoratti M, Szabo I, De Marchi U. (2005). Mitochondrial permeability transitions: how many doors to the house? Biochim Biophys Acta 1706: 40-52.
    • (2005) Biochim Biophys Acta , vol.1706 , pp. 40-52
    • Zoratti, M.1    Szabo, I.2    De Marchi, U.3


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