Caspase-mediated cleavage of β-catenin precedes drug-induced apoptosis in resistant cancer cells

Journal of Biological Chemistry

Volumn 284, Issue 20, 2009, Pages 13577-13588

  Senthivinayagam, Subramanian ^a   Mishra, Prajna ^a   Paramasivam, Suresh Kanna ^a   Yallapragada, Srinivas ^b   Chatterjee, Malay ^c   Wong, Lucas ^d   Rana, Ajay ^e,f   Rana, Basabi ^a,e,f  

^a LOYOLA UNIVERSITY CHICAGO   (United States)

^b TEXAS A AND M UNIVERSITY SYSTEM   (United States)

^c JADAVPUR UNIVERSITY   (India)

^d SCOTT AND WHITE MEMORIAL HOSPITAL   (United States)

^e LOYOLA UNIVERSITY CHICAGO   (United States)

^f VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS; APOPTOTIC; CANCER CELL GROWTH; CANCER CELLS; CASPASE; CASPASES; COLLATERAL DAMAGE; GENE SILENCING; GLYCOGEN SYNTHASE KINASE-3; IN-DEPTH STUDY; INDUCED APOPTOSIS; MOLECULAR TARGETS; ONCOGENESIS; OVER-EXPRESSION; PEROXISOME PROLIFERATOR-ACTIVATED RECEPTOR; SMALL INTERFERENCE RNA; THERAPEUTIC AGENTS; TUMOR CELLS; TUMOR NECROSIS FACTOR-RELATED APOPTOSIS-INDUCING LIGANDS; TUMORIGENESIS;

CELL GROWTH; CELL MEMBRANES; DRUG THERAPY; GENETIC ENGINEERING; GROWTH KINETICS; LIGANDS; NUCLEIC ACIDS; RNA; TUMORS;

CELL DEATH;

BETA CATENIN; CASPASE 3; CASPASE 8; GLYCOGEN SYNTHASE KINASE 3BETA; SMALL INTERFERING RNA; TROGLITAZONE; TUMOR NECROSIS FACTOR RELATED APOPTOSIS INDUCING LIGAND; 2,4 THIAZOLIDINEDIONE DERIVATIVE; ANTINEOPLASTIC AGENT; CASP3 PROTEIN, HUMAN; CASP8 PROTEIN, HUMAN; CHROMAN DERIVATIVE; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; TNFSF10 PROTEIN, HUMAN; TUMOR PROTEIN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CANCER CELL; CANCER RESISTANCE; CARBOXY TERMINAL SEQUENCE; CARCINOGENESIS; COLON CANCER; COMBINATION CHEMOTHERAPY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOWN REGULATION; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENTIATION; DRUG SENSITIZATION; DRUG TARGETING; EMBRYO; ENZYME ACTIVITY; FEMALE; GENE SILENCING; HUMAN; HUMAN CELL; LIVER CELL CARCINOMA; MALE; MOUSE; NONHUMAN; OVARY CANCER; PRIORITY JOURNAL; PROSTATE CANCER; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN PROCESSING; TIME; DRUG EFFECT; DRUG RESISTANCE; GENE EXPRESSION REGULATION; METABOLISM; NEOPLASM; TUMOR CELL LINE;

ANTINEOPLASTIC COMBINED CHEMOTHERAPY PROTOCOLS; APOPTOSIS; BETA CATENIN; CASPASE 3; CASPASE 8; CELL LINE, TUMOR; CHROMANS; DRUG RESISTANCE, NEOPLASM; GENE EXPRESSION REGULATION, NEOPLASTIC; GENE SILENCING; GLYCOGEN SYNTHASE KINASE 3; HUMANS; NEOPLASM PROTEINS; NEOPLASMS; PPAR GAMMA; RNA, SMALL INTERFERING; THIAZOLIDINEDIONES; TNF-RELATED APOPTOSIS-INDUCING LIGAND;

EID: 67649403612     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M900248200     Document Type: Article

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