Ochratoxin A - Mediated DNA and protein damage: Roles of nitrosative and oxidative stresses

Toxicological Sciences

Volumn 110, Issue 1, 2009, Pages 84-94

  Cavin, Christophe ^a,b   Delatour, Thierry ^b   Marin Kuan, Maricel ^a   Fenaille, François ^b   Holzhäuser, Daisy ^a   Guignard, Gabrièla ^a   Bezençon, Claudine ^a   Piguet, Dominique ^a   Parisod, Véronique ^a   Richoz Payot, Janique ^a   Schilter, Benoît ^a  

^a NESTLÉ RESEARCH CENTER   (Switzerland)

^b CEA SACLAY   (France)

Author keywords

Carcinogenicity; Inducible nitric oxide synthase; Mycotoxin; Nephrotoxicity; Nuclear factor erythroid 2 p45 related factor 2; Ochratoxin A; Oxidative and nitrosative stress

Indexed keywords

8 NITROGUANINE; HEME OXYGENASE 1; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INDUCIBLE NITRIC OXIDE SYNTHASE; OCHRATOXIN; TRANSCRIPTION FACTOR NRF2;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CARCINOGENICITY; CELL CULTURE; CONTROLLED STUDY; CYTOTOXICITY; DNA DAMAGE; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME INDUCTION; LIPID PEROXIDATION; LIVER CELL; MALE; NEPHROTOXICITY; NITRATION; NITROSATIVE STRESS; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION; RAT; SPRAGUE DAWLEY RAT; WESTERN BLOTTING;

ALDEHYDES; ANIMALS; BLOTTING, WESTERN; CARCINOGENS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; CYSTEINE PROTEINASE INHIBITORS; DNA DAMAGE; ELECTROPHORETIC MOBILITY SHIFT ASSAY; HEME OXYGENASE-1; MALE; NF-E2 TRANSCRIPTION FACTOR, P45 SUBUNIT; NF-KAPPA B; NITRIC OXIDE SYNTHASE TYPE II; OCHRATOXINS; RATS; RATS, SPRAGUE-DAWLEY; REACTIVE NITROGEN SPECIES; REACTIVE OXYGEN SPECIES; SPECTROMETRY, MASS, MATRIX-ASSISTED LASER DESORPTION-IONIZATION; TANDEM MASS SPECTROMETRY;

RATTUS; RODENTIA;

EID: 67649208209     PISSN: 10966080     EISSN: 10960929     Source Type: Journal    
DOI: 10.1093/toxsci/kfp090     Document Type: Article

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