-
1
-
-
0024723238
-
Risk assessment of the mycotoxin ochratoxin A
-
Kuiper-Goodman, T., and Scott, P. M. (1989) Risk assessment of the mycotoxin ochratoxin A. Biomed. Environ. Sci. 2, 179-248.
-
(1989)
Biomed. Environ. Sci.
, vol.2
, pp. 179-248
-
-
Kuiper-Goodman, T.1
Scott, P.M.2
-
2
-
-
10844291411
-
Ochratoxin A: A review
-
Pohland, A. E., Nesheim, S., and Friedman, L. (1992) Ochratoxin A: A review. Pure Appl. Chem. 64, 1029-1046.
-
(1992)
Pure Appl. Chem.
, vol.64
, pp. 1029-1046
-
-
Pohland, A.E.1
Nesheim, S.2
Friedman, L.3
-
3
-
-
4043143709
-
Determination of ochratoxin A in foods: State-of-the-art and analytical challenges
-
Monaci, L., and Palmisano, F. (2004) Determination of ochratoxin A in foods: State-of-the-art and analytical challenges. Anal. Bioanal. Chem. 378, 96-103.
-
(2004)
Anal. Bioanal. Chem.
, vol.378
, pp. 96-103
-
-
Monaci, L.1
Palmisano, F.2
-
4
-
-
9444298436
-
Molecular aspects of the transport and toxicity of ochratoxin A
-
Dai, J., Park, G., Perry, J. L., Il'ichev, Y. V., Bow, D. A. J., Pritchard, J. B., Faucet, V., Pfohl-Leszkowicz, A., Manderville, R. A., and Simon, J. D. (2004) Molecular aspects of the transport and toxicity of ochratoxin A. Acc. Chem. Res. 37, 874-881.
-
(2004)
Acc. Chem. Res.
, vol.37
, pp. 874-881
-
-
Dai, J.1
Park, G.2
Perry, J.L.3
Il'ichev, Y.V.4
Bow, D.A.J.5
Pritchard, J.B.6
Faucet, V.7
Pfohl-Leszkowicz, A.8
Manderville, R.A.9
Simon, J.D.10
-
6
-
-
0003808769
-
-
NIH Publication No. 89-2813, U.S. Department of Health and Human Services, National Institutes of Health, Research Triangle Park, NC
-
Boorman, G., Ed. (1989) NTP technical report on the toxicology and carcinogenesis studies of ochratoxin A (CAS No. 303-47-9) in F344/N rats (gavage studies). NIH Publication No. 89-2813, U.S. Department of Health and Human Services, National Institutes of Health, Research Triangle Park, NC.
-
(1989)
NTP Technical Report on the Toxicology and Carcinogenesis Studies of Ochratoxin A (CAS No. 303-47-9) in F344/N Rats (Gavage Studies)
-
-
Boorman, G.1
-
7
-
-
0032479415
-
Sex- and strain-specific induction of renal tumors by ochratoxin A in rats correlates with DNA adduction
-
Castegnaro, M., Mohr, U., Pfohl-Leszkowicz, A., Estève, J., Steinmann, J., Tillman, J., Michelon, J., and Bartsch, H. (1998) Sex- and strain-specific induction of renal tumors by ochratoxin A in rats correlates with DNA adduction. Int. J. Cancer 77, 70-75.
-
(1998)
Int. J. Cancer
, vol.77
, pp. 70-75
-
-
Castegnaro, M.1
Mohr, U.2
Pfohl-Leszkowicz, A.3
Estève, J.4
Steinmann, J.5
Tillman, J.6
Michelon, J.7
Bartsch, H.8
-
8
-
-
0000120660
-
Some naturally occurring substances: Food items and constituents, heterocyclic aromatic amines and mycotoxins
-
IARC (1993) Some naturally occurring substances: Food items and constituents, heterocyclic aromatic amines and mycotoxins. IARC Monogr. Eval. Carcinog. Risks Hum. 56, 489-524.
-
(1993)
IARC Monogr. Eval. Carcinog. Risks Hum.
, vol.56
, pp. 489-524
-
-
-
9
-
-
0036161508
-
Balkan endemic nephropathy and the associated urinary tract tumors: Review on etiological causes, potential role of mycotoxins
-
Pfohl-Leszkowicz, A., Petkova-Bocharova, T., Chernozemsky, I. N., and Castegnaro, M. (2002) Balkan endemic nephropathy and the associated urinary tract tumors: Review on etiological causes, potential role of mycotoxins. Food Addit. Contam. 19, 282-302.
-
(2002)
Food Addit. Contam.
, vol.19
, pp. 282-302
-
-
Pfohl-Leszkowicz, A.1
Petkova-Bocharova, T.2
Chernozemsky, I.N.3
Castegnaro, M.4
-
10
-
-
1842632241
-
Analysis of ochratoxin A in foods consumed by inhabitants from an area with Balkan endemic nephropathy: A 1 month follow-up study
-
Vrabcheva, T., Petkova-Bocharova, T., Grosso, F., Nikolov, I., Chernozemsky, I. N., Castegnaro, M., and Dragacci, S. (2004) Analysis of ochratoxin A in foods consumed by inhabitants from an area with Balkan endemic nephropathy: a 1 month follow-up study. J. Agric. Food Chem. 52, 2404-2410.
-
(2004)
J. Agric. Food Chem.
, vol.52
, pp. 2404-2410
-
-
Vrabcheva, T.1
Petkova-Bocharova, T.2
Grosso, F.3
Nikolov, I.4
Chernozemsky, I.N.5
Castegnaro, M.6
Dragacci, S.7
-
11
-
-
4444292962
-
-
(Miraglia, M., and Brera, C., Eds.), EU Reports, Brussels, Belgium
-
European Union (2002) Task 3.2.7. Assessment of Dietary Intake of Ochratoxin A by the Population of EU Member States (Miraglia, M., and Brera, C., Eds.) p 82, EU Reports, Brussels, Belgium.
-
(2002)
Task 3.2.7. Assessment of Dietary Intake of Ochratoxin A by the Population of EU Member States
, pp. 82
-
-
-
13
-
-
0001594703
-
Ochratoxin A: A mycotoxin of concern
-
(Bhatnagar, D., Lillehoj, E. B., and Arora, D. K., Eds.), Marcel Dekker, New York
-
Størmer, F. C. (1992) Ochratoxin A: A mycotoxin of concern. In Handbook of Applied Mycology (Bhatnagar, D., Lillehoj, E. B., and Arora, D. K., Eds.) pp 403-432, Marcel Dekker, New York.
-
(1992)
Handbook of Applied Mycology
, pp. 403-432
-
-
Størmer, F.C.1
-
14
-
-
0022599506
-
Interstrain comparison of hepatic and renal microsomal carcinogen metabolism and liver S9-mediated mutagenicity in DA and Lewis rats phenotyped as poor and extensive metabolizers of debrisoquine
-
Hietanen, E., Malaveille, C., Camus, A. M., Béréziat, J. C., Brun, G., Castegnaro, M., Michelon, J., Idle, J. R., and Bartsch, H. (1986) Interstrain comparison of hepatic and renal microsomal carcinogen metabolism and liver S9-mediated mutagenicity in DA and Lewis rats phenotyped as poor and extensive metabolizers of debrisoquine. Drug Metab. Dispos. 14, 118-126.
-
(1986)
Drug Metab. Dispos.
, vol.14
, pp. 118-126
-
-
Hietanen, E.1
Malaveille, C.2
Camus, A.M.3
Béréziat, J.C.4
Brun, G.5
Castegnaro, M.6
Michelon, J.7
Idle, J.R.8
Bartsch, H.9
-
15
-
-
0000501998
-
Is the oxidative pathway implicated in the genotoxicity of ochratoxin A?
-
John Libbey Eurotext Ltd.
-
Pfohl-Leszkowicz, A., Grosse, Y., Kane, A., Gharbi, A., Baudrimont, I., Obrecht, S., Creppy, E. E., and Dirheimer, G. (1993) Is the oxidative pathway implicated in the genotoxicity of ochratoxin A? Human Ochratoxicosis and Its Pathologies, Vol. 231, pp 129-140, John Libbey Eurotext Ltd.
-
(1993)
Human Ochratoxicosis and Its Pathologies
, vol.231
, pp. 129-140
-
-
Pfohl-Leszkowicz, A.1
Grosse, Y.2
Kane, A.3
Gharbi, A.4
Baudrimont, I.5
Obrecht, S.6
Creppy, E.E.7
Dirheimer, G.8
-
16
-
-
0020582221
-
Formation of (4R)- And (4S)-4-hydroxyochratoxin A and 10-hydroxyochratoxin A from ochratoxin a by rabbit liver microsomes
-
Størmer, F. C., Støren, O., Hansen, C. E., Pedersen, J. I., and Aasen, A. J. (1983) Formation of (4R)- and (4S)-4-hydroxyochratoxin A and 10-hydroxyochratoxin A from ochratoxin A by rabbit liver microsomes. Appl. Environ. Microbiol. 45, 1183-1187.
-
(1983)
Appl. Environ. Microbiol.
, vol.45
, pp. 1183-1187
-
-
Størmer, F.C.1
Støren, O.2
Hansen, C.E.3
Pedersen, J.I.4
Aasen, A.J.5
-
17
-
-
0032901070
-
Respective implication of cyclooxygenase and lipoxygenase in ochratoxin A genotoxicity on human epithelial lung cells
-
Pinelli, E., El Adlouni, C., Pipy, B., Quartulli, F., and Pfohl-Leszkowicz, A. (1999) Respective implication of cyclooxygenase and lipoxygenase in ochratoxin A genotoxicity on human epithelial lung cells. Environ. Toxicol. Pharmacol. 7, 95-107.
-
(1999)
Environ. Toxicol. Pharmacol.
, vol.7
, pp. 95-107
-
-
Pinelli, E.1
El Adlouni, C.2
Pipy, B.3
Quartulli, F.4
Pfohl-Leszkowicz, A.5
-
18
-
-
0028842217
-
Formation of ochratoxin A metabolites and DNA adducts in monkey kidney cells
-
Grosse, Y., Baudrimont, I., Castegnaro, M., Betbeder, A.-M., Creppy, E. E., Dirheimer, G., and Pfohl-Leszkowicz, A. (1995) Formation of ochratoxin A metabolites and DNA adducts in monkey kidney cells. Chem.-Biol. Interact. 95, 175-187.
-
(1995)
Chem.-Biol. Interact.
, vol.95
, pp. 175-187
-
-
Grosse, Y.1
Baudrimont, I.2
Castegnaro, M.3
Betbeder, A.-M.4
Creppy, E.E.5
Dirheimer, G.6
Pfohl-Leszkowicz, A.7
-
19
-
-
0031010463
-
Use of bronchial epithelial cells expressing human cytochrome P450 for study on metabolism and genotoxicity of ochratoxin A
-
Grosse, Y., Monje, M. C., Macé, K., Pfeifer, A., and Pfohl-Leszkowicz, A. (1997) Use of bronchial epithelial cells expressing human cytochrome P450 for study on metabolism and genotoxicity of ochratoxin A. In Vitro Toxicology 10, 93-102.
-
(1997)
In Vitro Toxicology
, vol.10
, pp. 93-102
-
-
Grosse, Y.1
Monje, M.C.2
Macé, K.3
Pfeifer, A.4
Pfohl-Leszkowicz, A.5
-
20
-
-
0034070895
-
Phenobarbital increases DNA adduct and metabolites formed by ochratoxin A: Role of CYP 2C9 and microsomal glutathione-S-transferase
-
El Adlouni, C., Pinelli, E., Azémar, B., Zaoui, D., Beaune, P., and Pfohl-Leszkowicz, A. (2000) Phenobarbital increases DNA adduct and metabolites formed by ochratoxin A: Role of CYP 2C9 and microsomal glutathione-S-transferase. Environ. Mol. Mutagen. 35, 123-131.
-
(2000)
Environ. Mol. Mutagen.
, vol.35
, pp. 123-131
-
-
El Adlouni, C.1
Pinelli, E.2
Azémar, B.3
Zaoui, D.4
Beaune, P.5
Pfohl-Leszkowicz, A.6
-
21
-
-
22544471317
-
Analysis for DNA adducts, ochratoxin A content and enzymes expression in kidneys of pigs exposed to mild experimental chronic ochratoxicosis
-
Petkova-Bocharova, T., El Adlouni, C., Faucet, V., Pfohl-Leszkowicz, A., and Mantle, P. (2003) Analysis for DNA adducts, ochratoxin A content and enzymes expression in kidneys of pigs exposed to mild experimental chronic ochratoxicosis. Facta Univ., Ser.: Med. Biol. 10, 111-115.
-
(2003)
Facta Univ., Ser.: Med. Biol.
, vol.10
, pp. 111-115
-
-
Petkova-Bocharova, T.1
El Adlouni, C.2
Faucet, V.3
Pfohl-Leszkowicz, A.4
Mantle, P.5
-
22
-
-
0141671914
-
Toxicokinetics of the mycotoxin ochratoxin A in F344 rats after oral administration
-
Zepnik, H., Voelkel, W., and Dekant, W. (2003) Toxicokinetics of the mycotoxin ochratoxin A in F344 rats after oral administration. Toxicol. Appl. Pharmacol. 192, 36-44.
-
(2003)
Toxicol. Appl. Pharmacol.
, vol.192
, pp. 36-44
-
-
Zepnik, H.1
Voelkel, W.2
Dekant, W.3
-
23
-
-
0031173050
-
Pharmacokinetics of ochratoxin A and its metabolites in rats
-
Li, S., Marquardt, R. R., Frohlich, A. A., Vitti, T. G., and Crow, G. (1997) Pharmacokinetics of ochratoxin A and its metabolites in rats. Toxicol. Appl. Pharmacol. 145, 82-90.
-
(1997)
Toxicol. Appl. Pharmacol.
, vol.145
, pp. 82-90
-
-
Li, S.1
Marquardt, R.R.2
Frohlich, A.A.3
Vitti, T.G.4
Crow, G.5
-
24
-
-
20444366170
-
Biotransformation and nephrotoxicity of ochratoxin B in rats
-
In press
-
Mally, A., Keim-Heusler, H., Amberg, A., Kurz, M., Zepnik, H., Mantle, P., Völkel, W., Hard, G. C., and Dekant, W. (2005) Biotransformation and nephrotoxicity of ochratoxin B in rats. Toxicol. Appl. Pharmacol. In press.
-
(2005)
Toxicol. Appl. Pharmacol.
-
-
Mally, A.1
Keim-Heusler, H.2
Amberg, A.3
Kurz, M.4
Zepnik, H.5
Mantle, P.6
Völkel, W.7
Hard, G.C.8
Dekant, W.9
-
25
-
-
0035148577
-
Metabolism of ochratoxin A: Absence of formation of genotoxic derivatives by human and rat enzymes
-
Gautier, J.-C., Richoz, J., Welti, D. H., Markovik, J., Gremaud, E., Guengerich, F. P., and Turesky, R. J. (2001) Metabolism of ochratoxin A: Absence of formation of genotoxic derivatives by human and rat enzymes. Chem. Res. Toxicol. 14, 34-45.
-
(2001)
Chem. Res. Toxicol.
, vol.14
, pp. 34-45
-
-
Gautier, J.-C.1
Richoz, J.2
Welti, D.H.3
Markovik, J.4
Gremaud, E.5
Guengerich, F.P.6
Turesky, R.J.7
-
26
-
-
0037070059
-
Metabolism and lack of DNA reactivity of the mycotoxin ochratoxin A in cultured rat and human primary hepatocytes
-
Gross-Steinmeyer, K., Weymann, J., Hege, H.-G., and Metzler, M. (2002) Metabolism and lack of DNA reactivity of the mycotoxin ochratoxin A in cultured rat and human primary hepatocytes. J. Agric. Food Chem. 50, 938-945.
-
(2002)
J. Agric. Food Chem.
, vol.50
, pp. 938-945
-
-
Gross-Steinmeyer, K.1
Weymann, J.2
Hege, H.-G.3
Metzler, M.4
-
27
-
-
1342310580
-
Ochratoxin A: Lack of formation of covalent DNA adducts
-
Mally, A., Zepnik, H., Wanek, P., Eder, E., Dingley, K., Ihmels, H., Völkel, W., and Dekant, W. (2004) Ochratoxin A: Lack of formation of covalent DNA adducts. Chem. Res. Toxicol. 17, 234-242.
-
(2004)
Chem. Res. Toxicol.
, vol.17
, pp. 234-242
-
-
Mally, A.1
Zepnik, H.2
Wanek, P.3
Eder, E.4
Dingley, K.5
Ihmels, H.6
Völkel, W.7
Dekant, W.8
-
28
-
-
0035082128
-
A kinetic study into the hydrolysis of the ochratoxins and analogues by carboxypeptidase A
-
Stander, M. A., Steyn, P. S., van der Westhuizen, F. H., and Payne, B. E. (2001) A kinetic study into the hydrolysis of the ochratoxins and analogues by carboxypeptidase A. Chem. Res. Toxicol. 14, 302-304.
-
(2001)
Chem. Res. Toxicol.
, vol.14
, pp. 302-304
-
-
Stander, M.A.1
Steyn, P.S.2
Van Der Westhuizen, F.H.3
Payne, B.E.4
-
29
-
-
0026265779
-
Genotoxicity of ochratoxin A and structurally related compounds in Escherichia coli strains: Studies on their mode of action
-
Malaveille, C., Brun, G., and Bartsch, H. (1991) Genotoxicity of ochratoxin A and structurally related compounds in Escherichia coli strains: Studies on their mode of action. IARC Sci. Publ. 261-266.
-
(1991)
IARC Sci. Publ.
, pp. 261-266
-
-
Malaveille, C.1
Brun, G.2
Bartsch, H.3
-
30
-
-
0028276212
-
Structure-activity studies in E. coli strains on ochratoxin A (OTA) and its analogues implicate a genotoxic free radical and a cytotoxic thiol derivative as reactive metabolites
-
Malaveille, C., Brun, G., and Bartsch, H. (1994) Structure-activity studies in E. coli strains on ochratoxin A (OTA) and its analogues implicate a genotoxic free radical and a cytotoxic thiol derivative as reactive metabolites. Mutat. Res. 307, 141-147.
-
(1994)
Mutat. Res.
, vol.307
, pp. 141-147
-
-
Malaveille, C.1
Brun, G.2
Bartsch, H.3
-
31
-
-
0034802670
-
Electrochemical oxidation of ochratoxin A: Correlation with 4-chlorophenol
-
Calcutt, M. W., Gillman, I. G., Noftle, R. E., and Manderville, R. A. (2001) Electrochemical oxidation of ochratoxin A: Correlation with 4-chlorophenol. Chem. Res. Toxicol. 14, 1266-1272.
-
(2001)
Chem. Res. Toxicol.
, vol.14
, pp. 1266-1272
-
-
Calcutt, M.W.1
Gillman, I.G.2
Noftle, R.E.3
Manderville, R.A.4
-
32
-
-
0032750345
-
Oxidation of ochratoxin a by an Fe-porphyrin system: Model for enzymatic activation and DNA cleavage
-
Gillman, I. G., Clark, T. N., and Manderville, R. A. (1999) Oxidation of ochratoxin A by an Fe-porphyrin system: Model for enzymatic activation and DNA cleavage. Chem. Res. Toxicol. 12, 1066-1076.
-
(1999)
Chem. Res. Toxicol.
, vol.12
, pp. 1066-1076
-
-
Gillman, I.G.1
Clark, T.N.2
Manderville, R.A.3
-
33
-
-
0038238354
-
Stoichiometric preference in copper-promoted oxidative DNA damage by ochratoxin A
-
Manderville, R. A., Calcutt, M. W., Dai, J., Park, G., Gillman, I. G., Noftle, R. E., Mohammed, A. K., Dizdaroglu, M., Rodriguez, H., and Akman, S. A. (2003) Stoichiometric preference in copper-promoted oxidative DNA damage by ochratoxin A. J. Inorg. Biochem. 95, 87-96.
-
(2003)
J. Inorg. Biochem.
, vol.95
, pp. 87-96
-
-
Manderville, R.A.1
Calcutt, M.W.2
Dai, J.3
Park, G.4
Gillman, I.G.5
Noftle, R.E.6
Mohammed, A.K.7
Dizdaroglu, M.8
Rodriguez, H.9
Akman, S.A.10
-
34
-
-
0013215589
-
Detection and characterization of a glutathione conjugate of ochratoxin A
-
Dai, J., Park, G., Wright, M. W., Adams, M., Akman, S. A., and Manderville, R. A. (2002) Detection and characterization of a glutathione conjugate of ochratoxin A. Chem. Res. Toxicol. 15, 1581-1588.
-
(2002)
Chem. Res. Toxicol.
, vol.15
, pp. 1581-1588
-
-
Dai, J.1
Park, G.2
Wright, M.W.3
Adams, M.4
Akman, S.A.5
Manderville, R.A.6
-
35
-
-
0000161894
-
Ochratoxin A acts as a photoactivatable DNA cleaving agent
-
Gillman, I. G., Yezek, J. M., and Manderville, R. A. (1998) Ochratoxin A acts as a photoactivatable DNA cleaving agent. Chem. Commun. 467-468.
-
(1998)
Chem. Commun.
, pp. 467-468
-
-
Gillman, I.G.1
Yezek, J.M.2
Manderville, R.A.3
-
36
-
-
0036988846
-
Photochemically catalyzed reaction of ochratoxin A with D- and L-cysteine
-
Brow, M. E., Dai, J., Park, M. W., Wright, M. W., Gillman, I. G., and Manderville, R. A. (2002) Photochemically catalyzed reaction of ochratoxin A with D- and L-cysteine. Photochem. Photobiol. 76, 649-656.
-
(2002)
Photochem. Photobiol.
, vol.76
, pp. 649-656
-
-
Brow, M.E.1
Dai, J.2
Park, M.W.3
Wright, M.W.4
Gillman, I.G.5
Manderville, R.A.6
-
37
-
-
0035892171
-
The pH-dependent primary photoreactions of ochratoxin a
-
Il'ichev, Y. V., Perry, J. L., Manderville, R. A., Chignell, C. F., and Simon, J. D. (2001) The pH-dependent primary photoreactions of ochratoxin A. J. Phys. Chem. B 105, 11369-11376.
-
(2001)
J. Phys. Chem. B
, vol.105
, pp. 11369-11376
-
-
Il'ichev, Y.V.1
Perry, J.L.2
Manderville, R.A.3
Chignell, C.F.4
Simon, J.D.5
-
38
-
-
0000933636
-
Formation and reactivity of 4-oxocyclohexa-2,5-dienylidene in the photolysis of 4-chlorophenol in aqueous solution at ambient temperature
-
Grabner, G., Richard, C., and Köhler, G. (1994) Formation and reactivity of 4-oxocyclohexa-2,5-dienylidene in the photolysis of 4-chlorophenol in aqueous solution at ambient temperature. J. Am. Chem. Soc. 116, 11470-11480.
-
(1994)
J. Am. Chem. Soc.
, vol.116
, pp. 11470-11480
-
-
Grabner, G.1
Richard, C.2
Köhler, G.3
-
39
-
-
0034973773
-
Common and uncommon cytochrome P450 reactions related to metabolism and chemical toxicity
-
Guengerich, F. P. (2001) Common and uncommon cytochrome P450 reactions related to metabolism and chemical toxicity. Chem. Res. Toxicol. 14, 611-650.
-
(2001)
Chem. Res. Toxicol.
, vol.14
, pp. 611-650
-
-
Guengerich, F.P.1
-
40
-
-
0017262966
-
Anaerobic release of fluoride from halothane. Relationship to the binding of halothane to hepatic cellular constituents
-
Van Dyke, R. A., and Gandolfi, A. J. (1976) Anaerobic release of fluoride from halothane. Relationship to the binding of halothane to hepatic cellular constituents. Drug Metab. Dispos. 4, 40-44.
-
(1976)
Drug Metab. Dispos.
, vol.4
, pp. 40-44
-
-
Van Dyke, R.A.1
Gandolfi, A.J.2
-
41
-
-
0026094269
-
Detection of cysteine conjugate metabolite adduct formation with specific mitochondrial proteins using antibodies raised against halothane metabolite adducts
-
Hayden, P. J., Ichimura, T., McCann, D. J., Pohl, L. R., and Stevens, J. L. (1991) Detection of cysteine conjugate metabolite adduct formation with specific mitochondrial proteins using antibodies raised against halothane metabolite adducts. J. Biol. Chem. 266, 18415-18418.
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 18415-18418
-
-
Hayden, P.J.1
Ichimura, T.2
McCann, D.J.3
Pohl, L.R.4
Stevens, J.L.5
-
42
-
-
10044237965
-
Ochratoxin A: Induction of (oxidative) DNA damage, cytotoxicity and apoptosis in mammalian cell lines and primary cells
-
Kamp, H. G., Eisenbrand, G., Schlatter, J., Wurth, K., and Janzowski, C. (2005) Ochratoxin A: Induction of (oxidative) DNA damage, cytotoxicity and apoptosis in mammalian cell lines and primary cells. Toxicology 206, 413-425.
-
(2005)
Toxicology
, vol.206
, pp. 413-425
-
-
Kamp, H.G.1
Eisenbrand, G.2
Schlatter, J.3
Wurth, K.4
Janzowski, C.5
-
43
-
-
0033231439
-
Myeloperoxidase-catalyzed redox-cycling of phenol promotes lipid peroxidation and thiol oxidation in HL-60 cells
-
Goldman, R., Claycamp, G. H., Sweetland, M. A., Sedlov, A. V., Tyurin, V. A., Kisin, E. R., Tyurina, Y. Y., Ritov, V. B., Wenger, S. L., Grant, S. G., and Kagan, V. (1999) Myeloperoxidase-catalyzed redox-cycling of phenol promotes lipid peroxidation and thiol oxidation in HL-60 cells. Free Radical Biol. Med. 27, 1050-1063.
-
(1999)
Free Radical Biol. Med.
, vol.27
, pp. 1050-1063
-
-
Goldman, R.1
Claycamp, G.H.2
Sweetland, M.A.3
Sedlov, A.V.4
Tyurin, V.A.5
Kisin, E.R.6
Tyurina, Y.Y.7
Ritov, V.B.8
Wenger, S.L.9
Grant, S.G.10
Kagan, V.11
-
44
-
-
0030913482
-
Cytochrome P450-catalyzed oxidation of halobenzene derivatives
-
Rietjens, I. M. C. M., den Besten, C., Hanzlink, R. P., and van Bladeren, P. J. (1997) Cytochrome P450-catalyzed oxidation of halobenzene derivatives. Chem. Res. Toxicol. 10, 629-635.
-
(1997)
Chem. Res. Toxicol.
, vol.10
, pp. 629-635
-
-
Rietjens, I.M.C.M.1
Den Besten, C.2
Hanzlink, R.P.3
Van Bladeren, P.J.4
-
45
-
-
0041307079
-
An oxygen-bonded C8-deoxy-guanosine nucleoside adduct of pentachlorophenol by peroxidase activation: Evidence for ambident CS reactivity by phenoxyl radicals
-
Dai, J., Wright, M. W., and Manderville, R. A. (2003) An oxygen-bonded C8-deoxy-guanosine nucleoside adduct of pentachlorophenol by peroxidase activation: evidence for ambident CS reactivity by phenoxyl radicals. Chem. Res. Toxicol. 16, 817-821.
-
(2003)
Chem. Res. Toxicol.
, vol.16
, pp. 817-821
-
-
Dai, J.1
Wright, M.W.2
Manderville, R.A.3
-
46
-
-
17644405444
-
Role of phenoxyl radicals in DNA adduction by chlorophenol xenobiotics following peroxidase activation
-
Dai, J., Sloat, A. L., Wright, M. W., and Manderville, R. A. (2005) Role of phenoxyl radicals in DNA adduction by chlorophenol xenobiotics following peroxidase activation. Chem. Res. Toxicol. 18, 771-779.
-
(2005)
Chem. Res. Toxicol.
, vol.18
, pp. 771-779
-
-
Dai, J.1
Sloat, A.L.2
Wright, M.W.3
Manderville, R.A.4
-
47
-
-
0034068228
-
Role of quinones in toxicology
-
Bolton, J. L., Trush, M. A., Penning, T. M., Dryhurst, G., and Monks, T. J. (2000) Role of quinones in toxicology. Chem. Res. Toxicol. 13, 135-160.
-
(2000)
Chem. Res. Toxicol.
, vol.13
, pp. 135-160
-
-
Bolton, J.L.1
Trush, M.A.2
Penning, T.M.3
Dryhurst, G.4
Monks, T.J.5
-
48
-
-
0032587901
-
8-aryladenine formation in calf thymus DNA from arenediazonium ions
-
8-aryladenine formation in calf thymus DNA from arenediazonium ions. Chem. Res. Toxicol. 12, 297-304.
-
(1999)
Chem. Res. Toxicol.
, vol.12
, pp. 297-304
-
-
Gannett, P.M.1
Powell, J.H.2
Rao, R.3
Shi, X.4
Lawson, T.5
Kolar, C.6
Toth, B.7
-
49
-
-
0031472574
-
Synthesis and miscoding specificity of oligodeoxynucleotide containing 8-phenyl-2́-deoxyguanosine
-
Kohda, K., Tsunomoto, H., Kasamatsu, T., Sawamura, F., Terashima, I., and Shibutani, S. (1997) Synthesis and miscoding specificity of oligodeoxynucleotide containing 8-phenyl-2́-deoxyguanosine. Chem. Res. Toxicol. 10, 1351-1358.
-
(1997)
Chem. Res. Toxicol.
, vol.10
, pp. 1351-1358
-
-
Kohda, K.1
Tsunomoto, H.2
Kasamatsu, T.3
Sawamura, F.4
Terashima, I.5
Shibutani, S.6
-
50
-
-
0022202239
-
Genotoxicity of ochratoxin A in mice: DNA single-strand break evaluation in spleen, liver and kidney
-
Creppy, E. E., Kane, A., Dirheimer, G., Lafarge-Frayssinet, C., Mousset, S., and Frayssinet, C. (1985) Genotoxicity of ochratoxin A in mice: DNA single-strand break evaluation in spleen, liver and kidney. Toxicol. Lett. 28, 29-35.
-
(1985)
Toxicol. Lett.
, vol.28
, pp. 29-35
-
-
Creppy, E.E.1
Kane, A.2
Dirheimer, G.3
Lafarge-Frayssinet, C.4
Mousset, S.5
Frayssinet, C.6
-
51
-
-
0035717799
-
Detection of ochratoxin A-induced DNA damage in MDCK cells by alkaline single cell gel electrophoresis (comet assay)
-
Lebrun, S., and Föllmann, W. (2002) Detection of ochratoxin A-induced DNA damage in MDCK cells by alkaline single cell gel electrophoresis (comet assay). Arch. Toxicol. 75, 734-741.
-
(2002)
Arch. Toxicol.
, vol.75
, pp. 734-741
-
-
Lebrun, S.1
Föllmann, W.2
-
52
-
-
4644370940
-
MESNA protects rats against nephrotoxicity but not carcinogenicity induced by ochratoxin A, implicating two separate pathways
-
Pfohl-Leszkowicz, A., Bartsch, H., Azémar, B., Mohr, U., Estève, J., and Castegnaro, M. (2002) MESNA protects rats against nephrotoxicity but not carcinogenicity induced by ochratoxin A, implicating two separate pathways. Facia Univ., Ser.: Med. Biol. 9, 57-63.
-
(2002)
Facia Univ., Ser.: Med. Biol.
, vol.9
, pp. 57-63
-
-
Pfohl-Leszkowicz, A.1
Bartsch, H.2
Azémar, B.3
Mohr, U.4
Estève, J.5
Castegnaro, M.6
-
53
-
-
3042628657
-
Effects of ochratoxin A on oxidative damage in rat kidney: Protective role of melatonin
-
Ozcelik, N., Soyoz, M., and Kilinc, I. (2004) Effects of ochratoxin A on oxidative damage in rat kidney: Protective role of melatonin. J. Appl. Toxicol. 24, 211-215.
-
(2004)
J. Appl. Toxicol.
, vol.24
, pp. 211-215
-
-
Ozcelik, N.1
Soyoz, M.2
Kilinc, I.3
-
54
-
-
19944427207
-
Ochratoxin A-induced DNA damage in human fibroblast: Protective effect of cyanidin 3-O-β-D-glucoside
-
Russo, A., La Fauci, L. L., Acquaviva, R., Campisi, A., Raciti, G., Scifo, C., Renis, M., Galvano, G., Vanella, A., and Galvano, F. (2005) Ochratoxin A-induced DNA damage in human fibroblast: Protective effect of cyanidin 3-O-β-D-glucoside. J. Nutr. Biochem. 16, 31-37.
-
(2005)
J. Nutr. Biochem.
, vol.16
, pp. 31-37
-
-
Russo, A.1
La Fauci, L.L.2
Acquaviva, R.3
Campisi, A.4
Raciti, G.5
Scifo, C.6
Renis, M.7
Galvano, G.8
Vanella, A.9
Galvano, F.10
-
55
-
-
0024246888
-
Lipid peroxidation as a possible cause of ochratoxin toxicity
-
Rahimtula, A. D., Bereziat, J. C., Bussacchini-Griot, V., and Bartsch, H. (1988) Lipid peroxidation as a possible cause of ochratoxin toxicity. Biochem. Pharmacol. 37, 4469-4477.
-
(1988)
Biochem. Pharmacol.
, vol.37
, pp. 4469-4477
-
-
Rahimtula, A.D.1
Bereziat, J.C.2
Bussacchini-Griot, V.3
Bartsch, H.4
-
56
-
-
0035873971
-
Oxidative damage and stress response from ochratoxin A exposure in rats
-
Gautier, J.-C., Holzhaeuser, D., Markovic, J., Gremaud, E., Schilter, B., and Turesky, R. J. (2001) Oxidative damage and stress response from ochratoxin A exposure in rats. Free Radical Biol. Med. 30, 1089-1098.
-
(2001)
Free Radical Biol. Med.
, vol.30
, pp. 1089-1098
-
-
Gautier, J.-C.1
Holzhaeuser, D.2
Markovic, J.3
Gremaud, E.4
Schilter, B.5
Turesky, R.J.6
-
57
-
-
0037145755
-
The role of oxidative stress in the ochratoxin A-mediated toxicity in proximal tubular cells
-
Schaaf, G. J., Nijmeijer, S. M., Maas, R. F., Roestenberg, P., de Groene, E. M., and Fink-Gremmels, J. (2002) The role of oxidative stress in the ochratoxin A-mediated toxicity in proximal tubular cells. Biochim. Biophys. Acta 1588, 149-158.
-
(2002)
Biochim. Biophys. Acta
, vol.1588
, pp. 149-158
-
-
Schaaf, G.J.1
Nijmeijer, S.M.2
Maas, R.F.3
Roestenberg, P.4
De Groene, E.M.5
Fink-Gremmels, J.6
-
58
-
-
0029959825
-
Free radical generation as induced by ochratoxin A and its analogues in bacteria (Bacillus brevis)
-
Hoehler, D., Marquardt, R. R., McIntosh, A. R., and Xiao, H. (1996) Free radical generation as induced by ochratoxin A and its analogues in bacteria (Bacillus brevis). J. Biol. Chem. 271. 27388-27394.
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 27388-27394
-
-
Hoehler, D.1
Marquardt, R.R.2
McIntosh, A.R.3
Xiao, H.4
-
59
-
-
0030926268
-
Induction of free radicals in hepatocytes, mitochondria and microsomes of rats by ochratoxin A and its analogues
-
Hoehler, D., Marquardt, R. R., McIntosh, A. R., and Hatch, G. M. (1997) Induction of free radicals in hepatocytes, mitochondria and microsomes of rats by ochratoxin A and its analogues. Biochim Biophys. Acta 1357, 225-233.
-
(1997)
Biochim Biophys. Acta
, vol.1357
, pp. 225-233
-
-
Hoehler, D.1
Marquardt, R.R.2
McIntosh, A.R.3
Hatch, G.M.4
-
60
-
-
0026277330
-
DNA-adduct formation in mice treated with ochratoxin A
-
(Castegnaro, M., Pleština, R., Dirheimer, G., Chernozemsky, I. V., and Bartsch, H., Eds.), IARC Sci. Publ. No. 115, Lyon
-
Pfohl-Leszkowicz, A., Chakor, K., Creppy, E. E., and Dirheimer, G. (1991) DNA-adduct formation in mice treated with ochratoxin A. In Mycotoxin, Endemic Nephropathy and urinary Tract Tumours (Castegnaro, M., Pleština, R., Dirheimer, G., Chernozemsky, I. V., and Bartsch, H., Eds.) pp 245-253, IARC Sci. Publ. No. 115, Lyon.
-
(1991)
Mycotoxin, Endemic Nephropathy and Urinary Tract Tumours
, pp. 245-253
-
-
Pfohl-Leszkowicz, A.1
Chakor, K.2
Creppy, E.E.3
Dirheimer, G.4
-
61
-
-
0027504933
-
Differential DNA adduct formation and disappearance in three mouse tissues after treatment with the mycotoxin ochratoxin A
-
Pfohl-Leszkowicz, A., Grosse, Y., Kane, A., Creppy, E. E., and Dirheimer, G. (1993) Differential DNA adduct formation and disappearance in three mouse tissues after treatment with the mycotoxin ochratoxin A. Mutat. Res. 289, 265-273.
-
(1993)
Mutat. Res.
, vol.289
, pp. 265-273
-
-
Pfohl-Leszkowicz, A.1
Grosse, Y.2
Kane, A.3
Creppy, E.E.4
Dirheimer, G.5
-
62
-
-
0004880032
-
Some human kidney tumours in France exhibited a specific ochratoxin A-DNA adduct pattern
-
Azémar, B., Pinelli, E., Plante, P., Escourrou, G., Petkova-Bocharova, T., and Pfohl-Leszkowicz, A. (1998) Some human kidney tumours in France exhibited a specific ochratoxin A-DNA adduct pattern. Rev. Med. Vet. 6, 653.
-
(1998)
Rev. Med. Vet.
, vol.6
, pp. 653
-
-
Azémar, B.1
Pinelli, E.2
Plante, P.3
Escourrou, G.4
Petkova-Bocharova, T.5
Pfohl-Leszkowicz, A.6
-
63
-
-
0037344929
-
Comparative responses to mode of oral administration and dose of ochratoxin A or nephrotoxic extract of Penicillium polonicum in rats
-
Miljkovic, A., Pfohl-Leszkowicz, A., Dobrota, M., and Mantle, P. G. (2002) Comparative responses to mode of oral administration and dose of ochratoxin A or nephrotoxic extract of Penicillium polonicum in rats. Exp. Toxicol. Pathol. 54, 305-312.
-
(2002)
Exp. Toxicol. Pathol.
, vol.54
, pp. 305-312
-
-
Miljkovic, A.1
Pfohl-Leszkowicz, A.2
Dobrota, M.3
Mantle, P.G.4
-
64
-
-
0031715601
-
Formation of DNA adducts in tissues of mice progeny through transplacental contamination after administration of a single dose of ochratoxin A to the pregnant mother
-
Petkova-Bocharova, T., Stoichev, I. T., Chernozemsky, I. N., and Pfohl-Leszkowicz, A. (1998) Formation of DNA adducts in tissues of mice progeny through transplacental contamination after administration of a single dose of ochratoxin A to the pregnant mother. Environ. Mol. Mutagen. 32, 155-162.
-
(1998)
Environ. Mol. Mutagen.
, vol.32
, pp. 155-162
-
-
Petkova-Bocharova, T.1
Stoichev, I.T.2
Chernozemsky, I.N.3
Pfohl-Leszkowicz, A.4
-
65
-
-
0000334668
-
Ochratoxin A-related DNA adducts in urinary tract tumours of Bulgarian subjects
-
(Phillips, D. H., Castegnaro, M., and Bartsch, H., Eds.) IARC Scientific Publication No. 134, Lyon, France
-
Pfohl-Leszkowicz, A., Grosse, Y., Castegnaro, M., Nicolov, I. G., Chernozemsky, I. N., Bartsch, A. M., Betbeder, A. M., Creppy, E. E., and Dirheimer, G. (1993) Ochratoxin A-related DNA adducts in urinary tract tumours of Bulgarian subjects. In Postlabeling Methods for Detection of DNA Adducts (Phillips, D. H., Castegnaro, M., and Bartsch, H., Eds.) IARC Scientific Publication No. 134, Lyon, France.
-
(1993)
Postlabeling Methods for Detection of DNA Adducts
-
-
Pfohl-Leszkowicz, A.1
Grosse, Y.2
Castegnaro, M.3
Nicolov, I.G.4
Chernozemsky, I.N.5
Bartsch, A.M.6
Betbeder, A.M.7
Creppy, E.E.8
Dirheimer, G.9
-
66
-
-
0030942015
-
Retinol, ascorbic acid and α-tocopherol prevent DNA adduct formation in mice treated with the mycotoxins ochratoxin A and zearalenone
-
Grosse, Y., Chekir-Ghedira, L., Hue, A., Obrecht-Pflumio, S., Dirheimer, G., Bacha, H., and Pfohl-Leszkowicz, A. (1997) Retinol, ascorbic acid and α-tocopherol prevent DNA adduct formation in mice treated with the mycotoxins ochratoxin A and zearalenone. Cancer Lett. 114, 225-229.
-
(1997)
Cancer Lett.
, vol.114
, pp. 225-229
-
-
Grosse, Y.1
Chekir-Ghedira, L.2
Hue, A.3
Obrecht-Pflumio, S.4
Dirheimer, G.5
Bacha, H.6
Pfohl-Leszkowicz, A.7
-
67
-
-
0030050658
-
Protection by indomethacin and aspirin against genotoxicity of ochratoxin A, particularly in the urinary bladder and kidney
-
Obrecht-Pflumio, S., Grosse, Y., Pfohl-Leszkowicz, A., and Dirheimer, G. (1996) Protection by indomethacin and aspirin against genotoxicity of ochratoxin A, particularly in the urinary bladder and kidney. Arch. Toxicol. 70, 244-248.
-
(1996)
Arch. Toxicol.
, vol.70
, pp. 244-248
-
-
Obrecht-Pflumio, S.1
Grosse, Y.2
Pfohl-Leszkowicz, A.3
Dirheimer, G.4
-
68
-
-
0034659115
-
In vitro DNA and dGMP adducts formation caused by ochratoxin A
-
Obrecht-Pflumio, S., and Dirheimer, G. (2000) In vitro DNA and dGMP adducts formation caused by ochratoxin A. Chem.-Biol. Interact. 127, 29-44.
-
(2000)
Chem.-Biol. Interact.
, vol.127
, pp. 29-44
-
-
Obrecht-Pflumio, S.1
Dirheimer, G.2
-
69
-
-
0035659452
-
Horseradish peroxidase mediates DNA and deoxyguanosine 3′-monophosphate adduct formation in the presence of ochratoxin A
-
Obrecht-Pflumio, S., and Dirheimer, G. (2001) Horseradish peroxidase mediates DNA and deoxyguanosine 3′-monophosphate adduct formation in the presence of ochratoxin A. Arch. Toxicol. 75, 583-590.
-
(2001)
Arch. Toxicol.
, vol.75
, pp. 583-590
-
-
Obrecht-Pflumio, S.1
Dirheimer, G.2
-
70
-
-
0037414317
-
Ochratoxin A forms a carbon-bonded C8-deoxyguanosine nucleoside adduct: Implications for C8 reactivity by a phenolic radical
-
Dai, J., Wright, M. W., and Manderville, R. A. (2003) Ochratoxin A forms a carbon-bonded C8-deoxyguanosine nucleoside adduct: Implications for C8 reactivity by a phenolic radical. J. Am. Chem. Soc. 125, 3716-3717.
-
(2003)
J. Am. Chem. Soc.
, vol.125
, pp. 3716-3717
-
-
Dai, J.1
Wright, M.W.2
Manderville, R.A.3
-
71
-
-
4644268330
-
Evidence for covalent DNA adduction by ochratoxin A following chronic exposure to rat and subacute exposure to pig
-
Faucet, V., Pfohl-Leszkowicz, A., Dai, J., Castegnaro, M., and Manderville, R. A. (2004) Evidence for covalent DNA adduction by ochratoxin A following chronic exposure to rat and subacute exposure to pig. Chem. Res. Toxicol. 17, 1289-1296.
-
(2004)
Chem. Res. Toxicol.
, vol.17
, pp. 1289-1296
-
-
Faucet, V.1
Pfohl-Leszkowicz, A.2
Dai, J.3
Castegnaro, M.4
Manderville, R.A.5
-
72
-
-
0031735953
-
Sex- and strain-specific expression of cytochrome P450s in ochratoxin A-induced genotoxicity and carcinogenicity in rats
-
Pfohl-Leszkowicz, A., Pinelli, E., Bartsch, H., Mohr, U., and Castegnaro, M. (1998) Sex- and strain-specific expression of cytochrome P450s in ochratoxin A-induced genotoxicity and carcinogenicity in rats. Mol. Carcinog. 23, 76-85.
-
(1998)
Mol. Carcinog.
, vol.23
, pp. 76-85
-
-
Pfohl-Leszkowicz, A.1
Pinelli, E.2
Bartsch, H.3
Mohr, U.4
Castegnaro, M.5
-
73
-
-
0032699716
-
Genotoxicity of ochratoxin A by Salmonella mutagenicity test after bioactivation by mouse kidney microsomes
-
Obrecht-Pflumio, S., Chassat, T., Dirheimer, G., and Marzin, D. (1999) Genotoxicity of ochratoxin A by Salmonella mutagenicity test after bioactivation by mouse kidney microsomes. Mutat. Res. 446, 95-102.
-
(1999)
Mutat. Res.
, vol.446
, pp. 95-102
-
-
Obrecht-Pflumio, S.1
Chassat, T.2
Dirheimer, G.3
Marzin, D.4
-
74
-
-
0030060757
-
Development of human cytochrome P450-expressing cell lines: Application in mutagenicity testing of ochratoxin A
-
De Groene, E. M., Hassing, I. G. A. M., Blom, M. J., Seinen, W., Fink-Gremmels, J., and Horbach, G. J. (1996) Development of human cytochrome P450-expressing cell lines: Application in mutagenicity testing of ochratoxin A. Cancer Res. 56, 299-304.
-
(1996)
Cancer Res.
, vol.56
, pp. 299-304
-
-
De Groene, E.M.1
Hassing, I.G.A.M.2
Blom, M.J.3
Seinen, W.4
Fink-Gremmels, J.5
Horbach, G.J.6
-
75
-
-
0035147426
-
Ochratoxin A-induced tumor formation: Is there a role of reactive ochratoxin A metabolites?
-
Zepnik, H., Pahler, A., Schauer, U., and Dekant, W. (2001) Ochratoxin A-induced tumor formation: is there a role of reactive ochratoxin A metabolites? Toxicol. Sci. 59, 59-67.
-
(2001)
Toxicol. Sci.
, vol.59
, pp. 59-67
-
-
Zepnik, H.1
Pahler, A.2
Schauer, U.3
Dekant, W.4
-
76
-
-
0038470827
-
Effects of the mycotoxin ochratoxin A in a bacterial and a mammalian in vitro mutagenicity test system
-
Follmann, W., and Lucas, S. (2003) Effects of the mycotoxin ochratoxin A in a bacterial and a mammalian in vitro mutagenicity test system. Arch. Toxicol. 77, 298-147.
-
(2003)
Arch. Toxicol.
, vol.77
, pp. 298-1147
-
-
Follmann, W.1
Lucas, S.2
-
77
-
-
0030462648
-
Carcinogenicity and kinetic aspects of ochratoxin A
-
Schlatter, C., Studer, R. J., and Rasonyi, T. (1996) Carcinogenicity and kinetic aspects of ochratoxin A. Food Addit. Contam. 13 (Suppl.), 43-44.
-
(1996)
Food Addit. Contam.
, vol.13
, Issue.SUPPL.
, pp. 43-44
-
-
Schlatter, C.1
Studer, R.J.2
Rasonyi, T.3
-
78
-
-
13144293044
-
Ochratoxin A: The continuing enigma
-
O'Brien, E., and Dietrich, D. R. (2005) Ochratoxin A: The continuing enigma. Crit. Rev. Toxicol. 35, 33-60.
-
(2005)
Crit. Rev. Toxicol.
, vol.35
, pp. 33-60
-
-
O'Brien, E.1
Dietrich, D.R.2
-
79
-
-
0036119764
-
Analysis of DNA adducts in rats exposed to pentachlorophenol
-
Lin, P.-H., La, D. K., Upton, P. B., and Swenberg, J. A. (2002) Analysis of DNA adducts in rats exposed to pentachlorophenol. Carcinogenesis 23, 365-369.
-
(2002)
Carcinogenesis
, vol.23
, pp. 365-369
-
-
Lin, P.-H.1
La, D.K.2
Upton, P.B.3
Swenberg, J.A.4
|