-
1
-
-
0016683691
-
Transfusion-associated hepatitis not due to viral hepatitis type A or B
-
Feinstone SM, Kapikian AZ, Purcell RH, Alter HJ, Holland PV. Transfusion-associated hepatitis not due to viral hepatitis type A or B. N. Engl. J. Med. 292(15), 767-770 (1975).
-
(1975)
N. Engl. J. Med
, vol.292
, Issue.15
, pp. 767-770
-
-
Feinstone, S.M.1
Kapikian, A.Z.2
Purcell, R.H.3
Alter, H.J.4
Holland, P.V.5
-
2
-
-
0024509701
-
Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome
-
Choo QL, Kuo G, Weiner AJ, Overby LR, Bradley DW, Houghton M. Isolation of a cDNA clone derived from a blood-borne non-A, non-B viral hepatitis genome. Science 244(4902), 359-362 (1989).
-
(1989)
Science
, vol.244
, Issue.4902
, pp. 359-362
-
-
Choo, Q.L.1
Kuo, G.2
Weiner, A.J.3
Overby, L.R.4
Bradley, D.W.5
Houghton, M.6
-
3
-
-
0024377134
-
Detection of antibody to hepatitis C virus in prospectively followed transfusion recipients with acute and chronic non-A, non-B hepatitis
-
Alter HJ, Purcell RH, Shih JW et al. Detection of antibody to hepatitis C virus in prospectively followed transfusion recipients with acute and chronic non-A, non-B hepatitis. N. Engl. J. Med. 321(22), 1494-1500 (1989).
-
(1989)
N. Engl. J. Med
, vol.321
, Issue.22
, pp. 1494-1500
-
-
Alter, H.J.1
Purcell, R.H.2
Shih, J.W.3
-
4
-
-
0034294827
-
Hepatitis C virus and eliminating post-transfusion hepatitis
-
Alter HJ, Houghton M. Hepatitis C virus and eliminating post-transfusion hepatitis. Nat. Med. 6, 1082-1086 (2000).
-
(2000)
Nat. Med
, vol.6
, pp. 1082-1086
-
-
Alter, H.J.1
Houghton, M.2
-
5
-
-
10744225097
-
-
Global burden of disease (GBD) for hepatitis C
-
Global burden of disease (GBD) for hepatitis C. J. Clin. Pharmacol. 44(1), 20-29 (2004).
-
(2004)
J. Clin. Pharmacol
, vol.44
, Issue.1
, pp. 20-29
-
-
-
6
-
-
0034635771
-
The role of parenteral antischistosomal therapy in the spread of hepatitis C virus in Egypt
-
Frank C, Mohamed MK, Strickland GT et al. The role of parenteral antischistosomal therapy in the spread of hepatitis C virus in Egypt. Lancet 355(9207), 887-891 (2000).
-
(2000)
Lancet
, vol.355
, Issue.9207
, pp. 887-891
-
-
Frank, C.1
Mohamed, M.K.2
Strickland, G.T.3
-
7
-
-
24944523179
-
Epidemiology of hepatitis B and hepatitis B virus infection in United States children
-
Shepard CW, Finelli L, Fiore AE, Bell BP. Epidemiology of hepatitis B and hepatitis B virus infection in United States children. Pediatr. Infect. Dis. J. 24(9), 755-760 (2005).
-
(2005)
Pediatr. Infect. Dis. J
, vol.24
, Issue.9
, pp. 755-760
-
-
Shepard, C.W.1
Finelli, L.2
Fiore, A.E.3
Bell, B.P.4
-
8
-
-
33646575004
-
Liver disease in Egypt: Hepatitis C superseded schistosomiasis as a result of iatrogenic and biological factors
-
Strickland GT. Liver disease in Egypt: hepatitis C superseded schistosomiasis as a result of iatrogenic and biological factors. Hepatology 43(5), 915-922 (2006).
-
(2006)
Hepatology
, vol.43
, Issue.5
, pp. 915-922
-
-
Strickland, G.T.1
-
9
-
-
34250679750
-
Epidemiology of hepatitis C virus infection
-
Alter MJ. Epidemiology of hepatitis C virus infection. World J. Gastroenterol. 13(17), 2436-2441 (2007).
-
(2007)
World J. Gastroenterol
, vol.13
, Issue.17
, pp. 2436-2441
-
-
Alter, M.J.1
-
10
-
-
0030955346
-
Epidemiology of hepatitis C
-
Alter MJ. Epidemiology of hepatitis C. Hepatology 26(3 Suppl. 1), 62-65 (1997).
-
(1997)
Hepatology
, vol.26
, Issue.3 SUPPL. 1
, pp. 62-65
-
-
Alter, M.J.1
-
11
-
-
0029793741
-
Risk factors for the transmission of hepatitis C
-
Zeuzem S, Teuber G, Lee JH, Ruster B, Roth WK. Risk factors for the transmission of hepatitis C. J. Hepatol. 24(2), 3-10 (1996).
-
(1996)
J. Hepatol
, vol.24
, Issue.2
, pp. 3-10
-
-
Zeuzem, S.1
Teuber, G.2
Lee, J.H.3
Ruster, B.4
Roth, W.K.5
-
12
-
-
15844389654
-
Routes of infection, viremia, and liver disease in blood donors found to have hepatitis C virus infection
-
Conry-Cantilena C, VanRaden M, Gibble J et al. Routes of infection, viremia, and liver disease in blood donors found to have hepatitis C virus infection. N. Engl. J. Med. 334(26), 1691-1696 (1996).
-
(1996)
N. Engl. J. Med
, vol.334
, Issue.26
, pp. 1691-1696
-
-
Conry-Cantilena, C.1
VanRaden, M.2
Gibble, J.3
-
13
-
-
0000330316
-
Epidemiology of hepatitis C virus infection in seven European Union countries: A critical analysis of the literature. HENCORE Group. (Hepatitis C European Network for Co-operative Research)
-
Touzet S, Kraemer L, Colin C et al. Epidemiology of hepatitis C virus infection in seven European Union countries: a critical analysis of the literature. HENCORE Group. (Hepatitis C European Network for Co-operative Research). Eur. J. Gastroenterol. Hepatol. 12(6), 667-678 (2000).
-
(2000)
Eur. J. Gastroenterol. Hepatol
, vol.12
, Issue.6
, pp. 667-678
-
-
Touzet, S.1
Kraemer, L.2
Colin, C.3
-
14
-
-
0033035928
-
Risk factors for acquisition of hepatitis C virus infection in blood donors: Results of a case - control study
-
Delage G, Infante-Rivard C, Chiavetta JA, Willems B, Pi D, Fast M. Risk factors for acquisition of hepatitis C virus infection in blood donors: results of a case - control study. Gastroenterology 116(4), 893-899 (1999).
-
(1999)
Gastroenterology
, vol.116
, Issue.4
, pp. 893-899
-
-
Delage, G.1
Infante-Rivard, C.2
Chiavetta, J.A.3
Willems, B.4
Pi, D.5
Fast, M.6
-
15
-
-
18244426165
-
Mother to child transmission of hepatitis C virus: Prospective study of risk factors and timing of infection in children born to women seronegative for HIV-1. Tuscany Study Group on Hepatitis C Virus Infection
-
Resti M, Azzari C, Mannelli F et al. Mother to child transmission of hepatitis C virus: prospective study of risk factors and timing of infection in children born to women seronegative for HIV-1. Tuscany Study Group on Hepatitis C Virus Infection. BMJ 317(7156), 437-441 (1998).
-
(1998)
BMJ
, vol.317
, Issue.7156
, pp. 437-441
-
-
Resti, M.1
Azzari, C.2
Mannelli, F.3
-
16
-
-
0034626073
-
Mother-to-child transmission of hepatitis C virus: Evidence for preventable peripartum transmission
-
Gibb DM, Goodall RL, Dunn DT et al. Mother-to-child transmission of hepatitis C virus: evidence for preventable peripartum transmission. Lancet 356(9233), 904-907 (2000).
-
(2000)
Lancet
, vol.356
, Issue.9233
, pp. 904-907
-
-
Gibb, D.M.1
Goodall, R.L.2
Dunn, D.T.3
-
17
-
-
0029092873
-
Does the healthy hepatitis C virus carrier state really exist? An analysis using polymerase chain reaction
-
Prieto M, Olaso V, Verdu C et al. Does the healthy hepatitis C virus carrier state really exist? An analysis using polymerase chain reaction. Hepatology 22(2), 413-417 (1995).
-
(1995)
Hepatology
, vol.22
, Issue.2
, pp. 413-417
-
-
Prieto, M.1
Olaso, V.2
Verdu, C.3
-
18
-
-
0028937538
-
Differential distribution of hepatitis C virus genotypes in patients with and without liver function abnormalities
-
Silini E, Bono F, Cividini A et al. Differential distribution of hepatitis C virus genotypes in patients with and without liver function abnormalities. Hepatology 21(2), 285-290 (1995).
-
(1995)
Hepatology
, vol.21
, Issue.2
, pp. 285-290
-
-
Silini, E.1
Bono, F.2
Cividini, A.3
-
19
-
-
0031891214
-
Interferon α treatment of HCV RNA carriers with persistently normal transaminase levels: A pilot randomized controlled study
-
Sangiovanni A, Morales R, Spinzi G et al. Interferon α treatment of HCV RNA carriers with persistently normal transaminase levels: a pilot randomized controlled study. Hepatology 27(3), 853-856 (1998).
-
(1998)
Hepatology
, vol.27
, Issue.3
, pp. 853-856
-
-
Sangiovanni, A.1
Morales, R.2
Spinzi, G.3
-
20
-
-
0034081839
-
Serum aspartate but not alanine aminotransferase levels help to predict the histological features of chronic hepatitis C viral infections in adults
-
Assy N, Minuk GY. Serum aspartate but not alanine aminotransferase levels help to predict the histological features of chronic hepatitis C viral infections in adults. Am. J. Gastroenterol. 95(6), 1545-1550 (2000).
-
(2000)
Am. J. Gastroenterol
, vol.95
, Issue.6
, pp. 1545-1550
-
-
Assy, N.1
Minuk, G.Y.2
-
21
-
-
0038300133
-
Is laparoscopy an advantage in the diagnosis of cirrhosis in chronic hepatitis C virus infection?
-
Wietzke-Braun P, Braun F, Schott P, Ramadori G. Is laparoscopy an advantage in the diagnosis of cirrhosis in chronic hepatitis C virus infection? World J. Gastroenterol. 9(4), 745-750 (2003).
-
(2003)
World J. Gastroenterol
, vol.9
, Issue.4
, pp. 745-750
-
-
Wietzke-Braun, P.1
Braun, F.2
Schott, P.3
Ramadori, G.4
-
22
-
-
0028947963
-
-
Di Bisceglie AM. Hepatitis C and hepatocellular carcinoma. Semin. Liver Dis. 15, 64-69 (1995).
-
Di Bisceglie AM. Hepatitis C and hepatocellular carcinoma. Semin. Liver Dis. 15, 64-69 (1995).
-
-
-
-
23
-
-
0033917644
-
Hepatitis C virus related cirrhosis: Time to occurrence of hepatocellular carcinoma and death
-
Degos F, Christidis C, Ganne-Carrie N et al. Hepatitis C virus related cirrhosis: time to occurrence of hepatocellular carcinoma and death. Gut 47(1), 131-136 (2000).
-
(2000)
Gut
, vol.47
, Issue.1
, pp. 131-136
-
-
Degos, F.1
Christidis, C.2
Ganne-Carrie, N.3
-
24
-
-
0031783001
-
Predictors of patient and graft survival following liver transplantation for hepatitis C
-
Charlton M, Seaberg E, Wiesner R et al. Predictors of patient and graft survival following liver transplantation for hepatitis C. Hepatology 28(3), 823-830 (1998).
-
(1998)
Hepatology
, vol.28
, Issue.3
, pp. 823-830
-
-
Charlton, M.1
Seaberg, E.2
Wiesner, R.3
-
25
-
-
0034030136
-
Cellular immune responses persist and humoral responses decrease two decades after recovery from a single-source outbreak of hepatitis C
-
Takaki A, Wiese M, Maertens G et al. Cellular immune responses persist and humoral responses decrease two decades after recovery from a single-source outbreak of hepatitis C. Nat. Med. 6(5), 578-582 (2000).
-
(2000)
Nat. Med
, vol.6
, Issue.5
, pp. 578-582
-
-
Takaki, A.1
Wiese, M.2
Maertens, G.3
-
26
-
-
0033064363
-
Association of the HLA-DRB1*01 allele with spontaneous viral clearance in an Irish cohort infected with hepatitis C virus via contaminated anti-D immunoglobulin
-
Barrett S, Ryan E, Crowe J. Association of the HLA-DRB1*01 allele with spontaneous viral clearance in an Irish cohort infected with hepatitis C virus via contaminated anti-D immunoglobulin. J. Hepatol. 30(6), 979-983 (1999).
-
(1999)
J. Hepatol
, vol.30
, Issue.6
, pp. 979-983
-
-
Barrett, S.1
Ryan, E.2
Crowe, J.3
-
27
-
-
0032408707
-
Classification, nomenclature, and database development for hepatitis C virus (HCV) and related viruses: Proposals for standardization. International Committee on Virus Taxonomy
-
Robertson B, Myers G, Howard C et al. Classification, nomenclature, and database development for hepatitis C virus (HCV) and related viruses: proposals for standardization. International Committee on Virus Taxonomy. Arch. Virol. 143(12), 2493-2503 (1998).
-
(1998)
Arch. Virol
, vol.143
, Issue.12
, pp. 2493-2503
-
-
Robertson, B.1
Myers, G.2
Howard, C.3
-
28
-
-
25844523297
-
Consensus proposals for a unified system of nomenclature of hepatitis C virus genotypes
-
Simmonds P, Bukh J, Combet C et al. Consensus proposals for a unified system of nomenclature of hepatitis C virus genotypes. Hepatology 42(4), 962-973 (2005).
-
(2005)
Hepatology
, vol.42
, Issue.4
, pp. 962-973
-
-
Simmonds, P.1
Bukh, J.2
Combet, C.3
-
29
-
-
20844441405
-
Comparison of hepatitis C virus NS5b and 5′ noncoding gene sequencing methods in a multicenter study
-
Laperche S, Lunel F, Izopet J et al. Comparison of hepatitis C virus NS5b and 5′ noncoding gene sequencing methods in a multicenter study. J. Clin. Microbiol. 43(2), 733-739 (2005).
-
(2005)
J. Clin. Microbiol
, vol.43
, Issue.2
, pp. 733-739
-
-
Laperche, S.1
Lunel, F.2
Izopet, J.3
-
30
-
-
32344436908
-
Unique NS5b hepatitis C virus gene sequence consensus database is essential for standardization of genotype determinations in multicenter epidemiological studies
-
Laperche S, Saune K, Deny P et al. Unique NS5b hepatitis C virus gene sequence consensus database is essential for standardization of genotype determinations in multicenter epidemiological studies. J. Clin. Microbiol. 44(2), 614-616 (2006).
-
(2006)
J. Clin. Microbiol
, vol.44
, Issue.2
, pp. 614-616
-
-
Laperche, S.1
Saune, K.2
Deny, P.3
-
31
-
-
36549067746
-
The changing epidemiology of hepatitis C virus infection in Europe
-
Esteban JI, Sauleda S, Quer J. The changing epidemiology of hepatitis C virus infection in Europe. J. Hepatol. 48(1), 148-162 (2008).
-
(2008)
J. Hepatol
, vol.48
, Issue.1
, pp. 148-162
-
-
Esteban, J.I.1
Sauleda, S.2
Quer, J.3
-
32
-
-
26444432835
-
Prevalence and treatment of hepatitis C virus genotypes 4, 5, and 6
-
Nguyen MH, Keeffe EB. Prevalence and treatment of hepatitis C virus genotypes 4, 5, and 6. Clin. Gastroenterol. Hepatol. 3(10 Suppl. 2), S97-S101 (2005).
-
(2005)
Clin. Gastroenterol. Hepatol
, vol.3
, Issue.10 SUPPL. 2
-
-
Nguyen, M.H.1
Keeffe, E.B.2
-
33
-
-
33745016896
-
Distribution of hepatitis C virus genotypes in the Middle East
-
Ramia S, Eid-Fares J. Distribution of hepatitis C virus genotypes in the Middle East. Int. J. Infect. Dis. 10(4), 272-277 (2006).
-
(2006)
Int. J. Infect. Dis
, vol.10
, Issue.4
, pp. 272-277
-
-
Ramia, S.1
Eid-Fares, J.2
-
34
-
-
34547576427
-
The epidemiology of hepatitis C infection in the United States
-
Rustgi VK. The epidemiology of hepatitis C infection in the United States. J. Gastroenterol. 42(7), 513-521 (2007).
-
(2007)
J. Gastroenterol
, vol.42
, Issue.7
, pp. 513-521
-
-
Rustgi, V.K.1
-
35
-
-
0034439425
-
Immunology of hepatitic C virus infection
-
Huang L, Koziel MJ. Immunology of hepatitic C virus infection. Curr. Opin. Gastroenterol. 16, 558-564 (2000).
-
(2000)
Curr. Opin. Gastroenterol
, vol.16
, pp. 558-564
-
-
Huang, L.1
Koziel, M.J.2
-
36
-
-
0034023105
-
Liver infiltrating T lymphocytes express interferon γ and inducible nitric oxide synthase in chronic hepatitis C virus infection
-
Schweyer S, Mihm S, Radzun HJ, Hartmann H, Fayyazi A. Liver infiltrating T lymphocytes express interferon γ and inducible nitric oxide synthase in chronic hepatitis C virus infection. Gut 46(2), 255-259 (2000).
-
(2000)
Gut
, vol.46
, Issue.2
, pp. 255-259
-
-
Schweyer, S.1
Mihm, S.2
Radzun, H.J.3
Hartmann, H.4
Fayyazi, A.5
-
37
-
-
0033052304
-
Hepatic stellate cell activation and liver fibrosis are associated with necroinflammatory injury and Th1-like response in chronic hepatitis C
-
Baroni GS, Pastorelli A, Manzin A et al. Hepatic stellate cell activation and liver fibrosis are associated with necroinflammatory injury and Th1-like response in chronic hepatitis C. Liver 19(3), 212-219 (1999).
-
(1999)
Liver
, vol.19
, Issue.3
, pp. 212-219
-
-
Baroni, G.S.1
Pastorelli, A.2
Manzin, A.3
-
38
-
-
0032522802
-
Disparate roles for TNF-α and Fas ligand in concanavalin A-induced hepatitis
-
Ksontini R, Colagiovanni DB, Josephs MD et al. Disparate roles for TNF-α and Fas ligand in concanavalin A-induced hepatitis. J. Immunol. 160(8), 4082-4089 (1998).
-
(1998)
J. Immunol
, vol.160
, Issue.8
, pp. 4082-4089
-
-
Ksontini, R.1
Colagiovanni, D.B.2
Josephs, M.D.3
-
39
-
-
0032885207
-
Propionibacterium acnes induces acute TNFα-mediated apoptosis of hepatocytes followed by inflammatory T-cell-mediated granulomatous hepatitis in mice
-
Chen YL, Yu CK, Lei HY. Propionibacterium acnes induces acute TNFα-mediated apoptosis of hepatocytes followed by inflammatory T-cell-mediated granulomatous hepatitis in mice. J. Biomed. Sci. 6(5), 349-356 (1999).
-
(1999)
J. Biomed. Sci
, vol.6
, Issue.5
, pp. 349-356
-
-
Chen, Y.L.1
Yu, C.K.2
Lei, H.Y.3
-
40
-
-
57649102577
-
+ regulatory T cells in persistent human viral infections
-
+ regulatory T cells in persistent human viral infections. Hum. Immunol. 69(11), 771-775 (2008).
-
(2008)
Hum. Immunol
, vol.69
, Issue.11
, pp. 771-775
-
-
Billerbeck, E.1
Thimme, R.2
-
41
-
-
50849115190
-
T cells with regulatory activity in hepatitis C virus infection: What we know and what we don't
-
Dolganiuc A, Szabo G. T cells with regulatory activity in hepatitis C virus infection: what we know and what we don't. J. Leukoc. Biol. 84(3), 614-622 (2008).
-
(2008)
J. Leukoc. Biol
, vol.84
, Issue.3
, pp. 614-622
-
-
Dolganiuc, A.1
Szabo, G.2
-
42
-
-
33645038201
-
Immunopathogenesis of hepatitis C virus infection: Multifaceted strategies subverting innate and adaptive immunity
-
Kanto T, Hayashi N. Immunopathogenesis of hepatitis C virus infection: multifaceted strategies subverting innate and adaptive immunity. Intern. Med. 45(4), 183-191 (2006).
-
(2006)
Intern. Med
, vol.45
, Issue.4
, pp. 183-191
-
-
Kanto, T.1
Hayashi, N.2
-
43
-
-
46749127338
-
Host genetic factors and antiviral immune responses to hepatitis C virus
-
12(3), 713-726, xi (2008)
-
Thio CL. Host genetic factors and antiviral immune responses to hepatitis C virus. Clin. Liver Dis. 12(3), 713-726, xi (2008).
-
(2008)
Clin. Liver Dis
-
-
Thio, C.L.1
-
44
-
-
43049138463
-
Inflammation and repair in viral hepatitis C
-
Neuman MG, Sha K, Esguerra R et al. Inflammation and repair in viral hepatitis C. Dig. Dis. Sci. 53(6), 1468-1487 (2008).
-
(2008)
Dig. Dis. Sci
, vol.53
, Issue.6
, pp. 1468-1487
-
-
Neuman, M.G.1
Sha, K.2
Esguerra, R.3
-
45
-
-
4444300866
-
Inflammation, damage repair, immune cells, and liver fibrosis: Specific or nonspecific, this is the question
-
Ramadori G, Saile B. Inflammation, damage repair, immune cells, and liver fibrosis: specific or nonspecific, this is the question. Gastroenterology 127(3), 997-1000 (2004).
-
(2004)
Gastroenterology
, vol.127
, Issue.3
, pp. 997-1000
-
-
Ramadori, G.1
Saile, B.2
-
46
-
-
1542504567
-
Portal tract fibrogenesis in the liver
-
Ramadori G, Saile B. Portal tract fibrogenesis in the liver. Lab. Invest. 84(2), 153-159 (2004).
-
(2004)
Lab. Invest
, vol.84
, Issue.2
, pp. 153-159
-
-
Ramadori, G.1
Saile, B.2
-
47
-
-
0033665277
-
Interferon α-2A and ribavirin therapy for hepatitis C recurrence after liver transplantation
-
Wietzke P, Braun F, Ringe B, Ramadori G. Interferon α-2A and ribavirin therapy for hepatitis C recurrence after liver transplantation. Transplant. Proc. 32(7), 2539-2542 (2000).
-
(2000)
Transplant. Proc
, vol.32
, Issue.7
, pp. 2539-2542
-
-
Wietzke, P.1
Braun, F.2
Ringe, B.3
Ramadori, G.4
-
48
-
-
0033516384
-
The scientific challenge of hepatitis C
-
Cohen J. The scientific challenge of hepatitis C. Science 285(5424), 26-30 (1999).
-
(1999)
Science
, vol.285
, Issue.5424
, pp. 26-30
-
-
Cohen, J.1
-
49
-
-
0025968921
-
Genetic organization and diversity of the hepatitis C virus
-
Choo QL, Richman KH, Han JH et al. Genetic organization and diversity of the hepatitis C virus. Proc. Natl Acad. Sci. USA 88(6), 2451-2455 (1991).
-
(1991)
Proc. Natl Acad. Sci. USA
, vol.88
, Issue.6
, pp. 2451-2455
-
-
Choo, Q.L.1
Richman, K.H.2
Han, J.H.3
-
50
-
-
0025991559
-
Gene mapping of the putative structural region of the hepatitis C virus genome by in vitro processing analysis
-
Hijikata M, Kato N, Ootsuyama Y, Nakagawa M, Shimotohno K. Gene mapping of the putative structural region of the hepatitis C virus genome by in vitro processing analysis. Proc. Natl Acad. Sci. USA 88(13), 5547-5551 (1991).
-
(1991)
Proc. Natl Acad. Sci. USA
, vol.88
, Issue.13
, pp. 5547-5551
-
-
Hijikata, M.1
Kato, N.2
Ootsuyama, Y.3
Nakagawa, M.4
Shimotohno, K.5
-
51
-
-
0028233530
-
Biosynthesis and biochemical properties of the hepatitis C virus core protein
-
Santolini E, Migliaccio G, La Monica N. Biosynthesis and biochemical properties of the hepatitis C virus core protein. J. Virol. 68(6), 3631-3641 (1994).
-
(1994)
J. Virol
, vol.68
, Issue.6
, pp. 3631-3641
-
-
Santolini, E.1
Migliaccio, G.2
La Monica, N.3
-
52
-
-
0028960887
-
Processing of the hepatitis C virus precursor protein
-
Shimotohno K, Tanji Y, Hirowatari Y, Komoda Y, Kato N, Hijikata M. Processing of the hepatitis C virus precursor protein. J. Hepatol. 22(1), 87-92 (1995).
-
(1995)
J. Hepatol
, vol.22
, Issue.1
, pp. 87-92
-
-
Shimotohno, K.1
Tanji, Y.2
Hirowatari, Y.3
Komoda, Y.4
Kato, N.5
Hijikata, M.6
-
53
-
-
0028265186
-
Analysis of N-terminal processing of hepatitis C virus nonstructural protein 2
-
Mizushima H, Hijikata M, Tanji Y, Kimura K, Shimotohno K. Analysis of N-terminal processing of hepatitis C virus nonstructural protein 2. J. Virol. 68(4), 2731-2734 (1994).
-
(1994)
J. Virol
, vol.68
, Issue.4
, pp. 2731-2734
-
-
Mizushima, H.1
Hijikata, M.2
Tanji, Y.3
Kimura, K.4
Shimotohno, K.5
-
54
-
-
0027163740
-
Two distinct proteinase activities required for the processing of a putative nonstructural precursor protein of hepatitis C virus
-
Hijikata M, Mizushima H, Akagi T et al. Two distinct proteinase activities required for the processing of a putative nonstructural precursor protein of hepatitis C virus. J. Virol. 67(8), 4665-4675 (1993).
-
(1993)
J. Virol
, vol.67
, Issue.8
, pp. 4665-4675
-
-
Hijikata, M.1
Mizushima, H.2
Akagi, T.3
-
55
-
-
0027436831
-
A second hepatitis C virus-encoded proteinase
-
Grakoui A, McCourt DW, Wychowski C, Feinstone SM, Rice CM. A second hepatitis C virus-encoded proteinase. Proc. Natl Acad. Sci. USA 90(22), 10583-10587 (1993).
-
(1993)
Proc. Natl Acad. Sci. USA
, vol.90
, Issue.22
, pp. 10583-10587
-
-
Grakoui, A.1
McCourt, D.W.2
Wychowski, C.3
Feinstone, S.M.4
Rice, C.M.5
-
56
-
-
0027176287
-
NS3 is a serine protease required for processing of hepatitis C virus polyprotein
-
Tomei L, Failla C, Santolini E, De Francesco R, La Monica N. NS3 is a serine protease required for processing of hepatitis C virus polyprotein. J. Virol. 67(7), 4017-4026 (1993).
-
(1993)
J. Virol
, vol.67
, Issue.7
, pp. 4017-4026
-
-
Tomei, L.1
Failla, C.2
Santolini, E.3
De Francesco, R.4
La Monica, N.5
-
57
-
-
0027287798
-
Nonstructural protein 3 of the hepatitis C virus encodes a serine-type proteinase required for cleavage at the NS3/4 and NS4/5 junctions
-
Bartenschlager R, Ahlborn-Laake L, Mous J, Jacobsen H. Nonstructural protein 3 of the hepatitis C virus encodes a serine-type proteinase required for cleavage at the NS3/4 and NS4/5 junctions. J. Virol. 67(7), 3835-3844 (1993).
-
(1993)
J. Virol
, vol.67
, Issue.7
, pp. 3835-3844
-
-
Bartenschlager, R.1
Ahlborn-Laake, L.2
Mous, J.3
Jacobsen, H.4
-
58
-
-
0029143143
-
Structure and function of the hepatitis C virus internal ribosome entry site
-
Wang C, Siddiqui A. Structure and function of the hepatitis C virus internal ribosome entry site. Curr. Top. Microbiol. Immunol. 203, 99-115 (1995).
-
(1995)
Curr. Top. Microbiol. Immunol
, vol.203
, pp. 99-115
-
-
Wang, C.1
Siddiqui, A.2
-
59
-
-
33749831058
-
Hepatitis C virus core protein: An update on its molecular biology, cellular functions and clinical implications
-
Irshad M, Dhar I. Hepatitis C virus core protein: an update on its molecular biology, cellular functions and clinical implications. Med. Princ. Pract. 15(6), 405-416 (2006).
-
(2006)
Med. Princ. Pract
, vol.15
, Issue.6
, pp. 405-416
-
-
Irshad, M.1
Dhar, I.2
-
60
-
-
34249024924
-
Replication of hepatitis C virus
-
Moradpour D, Penin F, Rice CM. Replication of hepatitis C virus. Nat. Rev. 5(6), 453-463 (2007).
-
(2007)
Nat. Rev
, vol.5
, Issue.6
, pp. 453-463
-
-
Moradpour, D.1
Penin, F.2
Rice, C.M.3
-
61
-
-
33746830410
-
Structural determinants that target the hepatitis C virus core protein to lipid droplets
-
Boulant S, Montserret R, Hope RG et al. Structural determinants that target the hepatitis C virus core protein to lipid droplets. J. Biol. Chem. 281(31), 22236-22247 (2006).
-
(2006)
J. Biol. Chem
, vol.281
, Issue.31
, pp. 22236-22247
-
-
Boulant, S.1
Montserret, R.2
Hope, R.G.3
-
62
-
-
29244484291
-
Steatosis in chronic hepatitis C: Why does it really matter?
-
Asselah T, Rubbia-Brandt L, Marcellin P, Negro F. Steatosis in chronic hepatitis C: why does it really matter? Gut 55(1), 123-130 (2006).
-
(2006)
Gut
, vol.55
, Issue.1
, pp. 123-130
-
-
Asselah, T.1
Rubbia-Brandt, L.2
Marcellin, P.3
Negro, F.4
-
63
-
-
33646024277
-
Cell entry of hepatitis C virus
-
Bartosch B, Cosset FL. Cell entry of hepatitis C virus. Virology 348(1), 1-12 (2006).
-
(2006)
Virology
, vol.348
, Issue.1
, pp. 1-12
-
-
Bartosch, B.1
Cosset, F.L.2
-
64
-
-
33646134842
-
Hepatitis C virus entry: Potential receptors and their biological functions
-
Cocquerel L, Voisset C, Dubuisson J. Hepatitis C virus entry: potential receptors and their biological functions. J. Gen. Virol. 87(Pt 5), 1075-1084 (2006).
-
(2006)
J. Gen. Virol
, vol.87
, Issue.PART 5
, pp. 1075-1084
-
-
Cocquerel, L.1
Voisset, C.2
Dubuisson, J.3
-
65
-
-
22544470874
-
Production of infectious hepatitis C virus in tissue culture from a cloned viral genome
-
Wakita T, Pietschmann T, Kato T et al. Production of infectious hepatitis C virus in tissue culture from a cloned viral genome. Nat. Med. 11(7), 791-796 (2005).
-
(2005)
Nat. Med
, vol.11
, Issue.7
, pp. 791-796
-
-
Wakita, T.1
Pietschmann, T.2
Kato, T.3
-
66
-
-
0036848564
-
Interaction of hepatitis C virus proteins with host cell membranes and lipids
-
Dubuisson J, Penin F, Moradpour D. Interaction of hepatitis C virus proteins with host cell membranes and lipids. Trends Cell Biol. 12(11), 517-523 (2002).
-
(2002)
Trends Cell Biol
, vol.12
, Issue.11
, pp. 517-523
-
-
Dubuisson, J.1
Penin, F.2
Moradpour, D.3
-
67
-
-
33748740828
-
Cyanovirin-N inhibits hepatitis C virus entry by binding to envelope protein glycans
-
Helle F, Wychowski C, Vu-Dac N, Gustafson KR, Voisset C, Dubuisson J. Cyanovirin-N inhibits hepatitis C virus entry by binding to envelope protein glycans. J. Biol. Chem. 281(35), 25177-25183 (2006).
-
(2006)
J. Biol. Chem
, vol.281
, Issue.35
, pp. 25177-25183
-
-
Helle, F.1
Wychowski, C.2
Vu-Dac, N.3
Gustafson, K.R.4
Voisset, C.5
Dubuisson, J.6
-
68
-
-
0032582538
-
Binding of hepatitis C virus to CD81
-
Pileri P, Uematsu Y, Campagnoli S et al. Binding of hepatitis C virus to CD81. Science 282(5390), 938-941 (1998).
-
(1998)
Science
, vol.282
, Issue.5390
, pp. 938-941
-
-
Pileri, P.1
Uematsu, Y.2
Campagnoli, S.3
-
69
-
-
18644378971
-
The human scavenger receptor class B type I is a novel candidate receptor for the hepatitis C virus
-
Scarselli E, Ansuini H, Cerino R et al. The human scavenger receptor class B type I is a novel candidate receptor for the hepatitis C virus. EMBO J. 21(19), 5017-5025 (2002).
-
(2002)
EMBO J
, vol.21
, Issue.19
, pp. 5017-5025
-
-
Scarselli, E.1
Ansuini, H.2
Cerino, R.3
-
70
-
-
17044457135
-
Cellular binding of hepatitis C virus envelope glycoprotein E2 requires cell surface heparan sulfate
-
Barth H, Schafer C, Adah MI et al. Cellular binding of hepatitis C virus envelope glycoprotein E2 requires cell surface heparan sulfate. J. Biol. Chem. 278(42), 41003-41012 (2003).
-
(2003)
J. Biol. Chem
, vol.278
, Issue.42
, pp. 41003-41012
-
-
Barth, H.1
Schafer, C.2
Adah, M.I.3
-
71
-
-
0037447255
-
L-SIGN (CD 209L) is a liver-specific capture receptor for hepatitis C virus
-
Gardner JP, Durso RJ, Arrigale RR et al. L-SIGN (CD 209L) is a liver-specific capture receptor for hepatitis C virus. Proc. Natl Acad. Sci. USA 100(8), 4498-4503 (2003).
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, Issue.8
, pp. 4498-4503
-
-
Gardner, J.P.1
Durso, R.J.2
Arrigale, R.R.3
-
72
-
-
0038165533
-
DC-SIGN and L-SIGN are high affinity binding receptors for hepatitis C virus glycoprotein E2
-
Lozach PY, Lortat-Jacob H, de Lacroix de Lavalette A et al. DC-SIGN and L-SIGN are high affinity binding receptors for hepatitis C virus glycoprotein E2. J. Biol. Chem. 278(22), 20358-20366 (2003).
-
(2003)
J. Biol. Chem
, vol.278
, Issue.22
, pp. 20358-20366
-
-
Lozach, P.Y.1
Lortat-Jacob, H.2
de Lacroix de Lavalette, A.3
-
73
-
-
0033607281
-
Hepatitis C virus and other flaviviridae viruses enter cells via low density lipoprotein receptor
-
Agnello V, Abel G, Elfahal M, Knight GB, Zhang QX. Hepatitis C virus and other flaviviridae viruses enter cells via low density lipoprotein receptor. Proc. Natl Acad. Sci. USA 96(22), 12766-12771 (1999).
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, Issue.22
, pp. 12766-12771
-
-
Agnello, V.1
Abel, G.2
Elfahal, M.3
Knight, G.B.4
Zhang, Q.X.5
-
74
-
-
0345251979
-
Low density lipoprotein receptor as a candidate receptor for hepatitis C virus
-
Monazahian M, Bohme I, Bonk S et al. Low density lipoprotein receptor as a candidate receptor for hepatitis C virus. J. Med. Virol. 57(3), 223-229 (1999).
-
(1999)
J. Med. Virol
, vol.57
, Issue.3
, pp. 223-229
-
-
Monazahian, M.1
Bohme, I.2
Bonk, S.3
-
75
-
-
0036199092
-
Subcellular localization and topology of the p7 polypeptide of hepatitis C virus
-
Carrere-Kremer S, Montpellier-Pala C, Cocquerel L, Wychowski C, Penin F, Dubuisson J. Subcellular localization and topology of the p7 polypeptide of hepatitis C virus. J. Virol. 76(8), 3720-3730 (2002).
-
(2002)
J. Virol
, vol.76
, Issue.8
, pp. 3720-3730
-
-
Carrere-Kremer, S.1
Montpellier-Pala, C.2
Cocquerel, L.3
Wychowski, C.4
Penin, F.5
Dubuisson, J.6
-
76
-
-
0028290389
-
Processing in the hepatitis C virus E2-NS2 region: Identification of p7 and two distinct E2-specific products with different C termini
-
Lin C, Lindenbach BD, Pragai BM, McCourt DW, Rice CM. Processing in the hepatitis C virus E2-NS2 region: identification of p7 and two distinct E2-specific products with different C termini. J. Virol. 68(8), 5063-5073 (1994).
-
(1994)
J. Virol
, vol.68
, Issue.8
, pp. 5063-5073
-
-
Lin, C.1
Lindenbach, B.D.2
Pragai, B.M.3
McCourt, D.W.4
Rice, C.M.5
-
77
-
-
33846005485
-
Evidence for the formation of a heptameric ion channel complex by the hepatitis C virus p7 protein in vitro
-
Clarke D, Griffin S, Beales L et al. Evidence for the formation of a heptameric ion channel complex by the hepatitis C virus p7 protein in vitro. J. Biol. Chem. 281(48), 37057-37068 (2006).
-
(2006)
J. Biol. Chem
, vol.281
, Issue.48
, pp. 37057-37068
-
-
Clarke, D.1
Griffin, S.2
Beales, L.3
-
78
-
-
0141816748
-
The p7 polypeptide of hepatitis C virus is critical for infectivity and contains functionally important genotype-specific sequences
-
Sakai A, Claire MS, Faulk K et al. The p7 polypeptide of hepatitis C virus is critical for infectivity and contains functionally important genotype-specific sequences. Proc. Natl Acad. Sci. USA 100(20), 11646-11651 (2003).
-
(2003)
Proc. Natl Acad. Sci. USA
, vol.100
, Issue.20
, pp. 11646-11651
-
-
Sakai, A.1
Claire, M.S.2
Faulk, K.3
-
79
-
-
0037472806
-
The p7 protein of hepatitis C virus forms an ion channel that is blocked by the antiviral drug, amantadine
-
Griffin SD, Beales LP, Clarke DS et al. The p7 protein of hepatitis C virus forms an ion channel that is blocked by the antiviral drug, amantadine. FEBS Lett. 535(1-3), 34-38 (2003).
-
(2003)
FEBS Lett
, vol.535
, Issue.1-3
, pp. 34-38
-
-
Griffin, S.D.1
Beales, L.P.2
Clarke, D.S.3
-
80
-
-
34547616693
-
Hepatitis C virus p7 protein is crucial for assembly and release of infectious virions
-
Steinmann E, Penin F, Kallis S, Patel AH, Bartenschlager R, Pietschmann T. Hepatitis C virus p7 protein is crucial for assembly and release of infectious virions. PLoS Pathog. 3(7), e103 (2007).
-
(2007)
PLoS Pathog
, vol.3
, Issue.7
-
-
Steinmann, E.1
Penin, F.2
Kallis, S.3
Patel, A.H.4
Bartenschlager, R.5
Pietschmann, T.6
-
81
-
-
0033608212
-
The hepatitis C virus NS2 protein generated by NS2-3 autocleavage is required for NS5A phosphorylation
-
Liu Q, Bhat RA, Prince AM, Zhang P. The hepatitis C virus NS2 protein generated by NS2-3 autocleavage is required for NS5A phosphorylation. Biochem. Biophys. Res. Commun. 254(3), 572-577 (1999).
-
(1999)
Biochem. Biophys. Res. Commun
, vol.254
, Issue.3
, pp. 572-577
-
-
Liu, Q.1
Bhat, R.A.2
Prince, A.M.3
Zhang, P.4
-
82
-
-
0037455560
-
Hepatitis C virus NS2 protein inhibits gene expression from different cellular and viral promoters in hepatic and nonhepatic cell lines
-
Dumoulin FL, von dem Bussche A, Li J et al. Hepatitis C virus NS2 protein inhibits gene expression from different cellular and viral promoters in hepatic and nonhepatic cell lines. Virology 305(2), 260-266 (2003).
-
(2003)
Virology
, vol.305
, Issue.2
, pp. 260-266
-
-
Dumoulin, F.L.1
von dem2
Bussche, A.3
Li, J.4
-
83
-
-
33748741785
-
Hepatitis C virus NS2 and NS3/4A proteins are potent inhibitors of host cell cytokine/ chemokine gene expression
-
Kaukinen P, Sillanpaa M, Kotenko S et al. Hepatitis C virus NS2 and NS3/4A proteins are potent inhibitors of host cell cytokine/ chemokine gene expression. Virol. J. 3, 66 (2006).
-
(2006)
Virol. J
, vol.3
, pp. 66
-
-
Kaukinen, P.1
Sillanpaa, M.2
Kotenko, S.3
-
84
-
-
23044437222
-
Complete replication of hepatitis C virus in cell culture
-
Lindenbach BD, Evans MJ, Syder AJ et al. Complete replication of hepatitis C virus in cell culture. Science 309(5734), 623-626 (2005).
-
(2005)
Science
, vol.309
, Issue.5734
, pp. 623-626
-
-
Lindenbach, B.D.1
Evans, M.J.2
Syder, A.J.3
-
85
-
-
34547734952
-
Hepatitis C virus p7 and NS2 proteins are essential for production of infectious virus
-
Jones CT, Murray CL, Eastman DK, Tassello J, Rice CM. Hepatitis C virus p7 and NS2 proteins are essential for production of infectious virus. J. Virol. 81(16), 8374-8383 (2007).
-
(2007)
J. Virol
, vol.81
, Issue.16
, pp. 8374-8383
-
-
Jones, C.T.1
Murray, C.L.2
Eastman, D.K.3
Tassello, J.4
Rice, C.M.5
-
86
-
-
16044364658
-
Crystal structure of the hepatitis C virus NS3 protease domain complexed with a synthetic NS4A cofactor peptide
-
Kim JL, Morgenstern KA, Lin C et al. Crystal structure of the hepatitis C virus NS3 protease domain complexed with a synthetic NS4A cofactor peptide. Cell 87(2), 343-355 (1996).
-
(1996)
Cell
, vol.87
, Issue.2
, pp. 343-355
-
-
Kim, J.L.1
Morgenstern, K.A.2
Lin, C.3
-
87
-
-
0030592514
-
The crystal structure of hepatitis C virus NS3 proteinase reveals a trypsin-like fold and a structural zinc binding site
-
Love RA, Parge HE, Wickersham JA et al. The crystal structure of hepatitis C virus NS3 proteinase reveals a trypsin-like fold and a structural zinc binding site. Cell 87(2), 331-342 (1996).
-
(1996)
Cell
, vol.87
, Issue.2
, pp. 331-342
-
-
Love, R.A.1
Parge, H.E.2
Wickersham, J.A.3
-
88
-
-
23944476834
-
Unravelling hepatitis C virus replication from genome to function
-
Lindenbach BD, Rice CM. Unravelling hepatitis C virus replication from genome to function. Nature 436(7053), 933-938 (2005).
-
(2005)
Nature
, vol.436
, Issue.7053
, pp. 933-938
-
-
Lindenbach, B.D.1
Rice, C.M.2
-
89
-
-
0037687422
-
Regulation of interferon regulatory factor-3 by the hepatitis C virus serine protease
-
Foy E, Li K, Wang C et al. Regulation of interferon regulatory factor-3 by the hepatitis C virus serine protease. Science 300(5622), 1145-1148 (2003).
-
(2003)
Science
, vol.300
, Issue.5622
, pp. 1145-1148
-
-
Foy, E.1
Li, K.2
Wang, C.3
-
90
-
-
27144440476
-
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
-
Meylan E, Curran J, Hofmann K et al. Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus. Nature 437(7062), 1167-1172 (2005).
-
(2005)
Nature
, vol.437
, Issue.7062
, pp. 1167-1172
-
-
Meylan, E.1
Curran, J.2
Hofmann, K.3
-
91
-
-
27544440303
-
Hitching RIG to action
-
Sen GC, Sarkar SN. Hitching RIG to action. Nat. Immunol. 6(11), 1074-1076 (2005).
-
(2005)
Nat. Immunol
, vol.6
, Issue.11
, pp. 1074-1076
-
-
Sen, G.C.1
Sarkar, S.N.2
-
92
-
-
29144462494
-
Hepatitis C virus protease NS3/ 4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunity
-
Li XD, Sun L, Seth RB, Pineda G, Chen ZJ. Hepatitis C virus protease NS3/ 4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunity. Proc. Natl Acad. Sci. USA 102(49), 17717-17722 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, Issue.49
, pp. 17717-17722
-
-
Li, X.D.1
Sun, L.2
Seth, R.B.3
Pineda, G.4
Chen, Z.J.5
-
93
-
-
14544280209
-
Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF
-
Li K, Foy E, Ferreon JC et al. Immune evasion by hepatitis C virus NS3/4A protease-mediated cleavage of the Toll-like receptor 3 adaptor protein TRIF. Proc. Natl Acad. Sci. USA 102(8), 2992-2997 (2005).
-
(2005)
Proc. Natl Acad. Sci. USA
, vol.102
, Issue.8
, pp. 2992-2997
-
-
Li, K.1
Foy, E.2
Ferreon, J.C.3
-
94
-
-
4644281168
-
An N-terminal amphipathic helix in hepatitis C virus (HCV) NS4B mediates membrane association, correct localization of replication complex proteins, and HCV RNA replication
-
Elazar M, Liu P, Rice CM, Glenn JS. An N-terminal amphipathic helix in hepatitis C virus (HCV) NS4B mediates membrane association, correct localization of replication complex proteins, and HCV RNA replication. J. Virol. 78 (20), 11393-11400 (2004).
-
(2004)
J. Virol
, vol.78
, Issue.20
, pp. 11393-11400
-
-
Elazar, M.1
Liu, P.2
Rice, C.M.3
Glenn, J.S.4
-
95
-
-
55249106707
-
A genetic interaction between hepatitis C virus NS4B and NS3 is important for RNA replication
-
Paredes AM, Blight KJ. A genetic interaction between hepatitis C virus NS4B and NS3 is important for RNA replication. J. Virol 82(21), 10671-10683 (2008).
-
(2008)
J. Virol
, vol.82
, Issue.21
, pp. 10671-10683
-
-
Paredes, A.M.1
Blight, K.J.2
-
96
-
-
60049083503
-
The hepatitis C virus NS4B protein can trans-complement viral RNA replication and modulates production of infectious virus
-
Jones DM, Patel AH, Targett Adams P, McLauchlan J. The hepatitis C virus NS4B protein can trans-complement viral RNA replication and modulates production of infectious virus. J. Virol. 83(5), 2163-2177 (2009).
-
(2009)
J. Virol
, vol.83
, Issue.5
, pp. 2163-2177
-
-
Jones, D.M.1
Patel, A.H.2
Targett Adams, P.3
McLauchlan, J.4
-
97
-
-
4644260669
-
Structure and function of the membrane anchor domain of hepatitis C virus nonstructural protein 5A
-
Penin F, Brass V, Appel N et al. Structure and function of the membrane anchor domain of hepatitis C virus nonstructural protein 5A. J. Biol. Chem. 279(39), 40835-40843 (2004).
-
(2004)
J. Biol. Chem
, vol.279
, Issue.39
, pp. 40835-40843
-
-
Penin, F.1
Brass, V.2
Appel, N.3
-
98
-
-
0028978937
-
Phosphorylation of hepatitis C virus-encoded nonstructural protein NS5A
-
Tanji Y, Kaneko T, Satoh S, Shimotohno K. Phosphorylation of hepatitis C virus-encoded nonstructural protein NS5A. J. Virol. 69(7), 3980-3986 (1995).
-
(1995)
J. Virol
, vol.69
, Issue.7
, pp. 3980-3986
-
-
Tanji, Y.1
Kaneko, T.2
Satoh, S.3
Shimotohno, K.4
-
99
-
-
10344221613
-
The NS5A protein of hepatitis C virus is a zinc metalloprotein
-
Tellinghuisen TL, Marcotrigiano J, Gorbalenya AE, Rice CM. The NS5A protein of hepatitis C virus is a zinc metalloprotein. J. Biol. Chem. 279(47), 48576-48587 (2004).
-
(2004)
J. Biol. Chem
, vol.279
, Issue.47
, pp. 48576-48587
-
-
Tellinghuisen, T.L.1
Marcotrigiano, J.2
Gorbalenya, A.E.3
Rice, C.M.4
-
100
-
-
19644393931
-
Structure of the zinc-binding domain of an essential component of the hepatitis C virus replicase
-
Tellinghuisen TL, Marcotrigiano J, Rice CM. Structure of the zinc-binding domain of an essential component of the hepatitis C virus replicase. Nature 435(7040), 374-379 (2005).
-
(2005)
Nature
, vol.435
, Issue.7040
, pp. 374-379
-
-
Tellinghuisen, T.L.1
Marcotrigiano, J.2
Rice, C.M.3
-
101
-
-
17144463221
-
Control of PKR protein kinase by hepatitis C virus nonstructural 5A protein: Molecular mechanisms of kinase regulation
-
Gale M Jr, Blakely CM, Kwieciszewski B et al. Control of PKR protein kinase by hepatitis C virus nonstructural 5A protein: molecular mechanisms of kinase regulation. Mol. Cell. Biol. 18(9), 5208-5218 (1998).
-
(1998)
Mol. Cell. Biol
, vol.18
, Issue.9
, pp. 5208-5218
-
-
Gale Jr, M.1
Blakely, C.M.2
Kwieciszewski, B.3
-
102
-
-
0344765507
-
Repression of the PKR protein kinase by the hepatitis C virus NS5A protein: A potential mechanism of interferon resistance
-
Gale MJ Jr, Korth MJ, Katze MG. Repression of the PKR protein kinase by the hepatitis C virus NS5A protein: a potential mechanism of interferon resistance. Clin. Diagn. Virol. 10(2-3), 157-162 (1998).
-
(1998)
Clin. Diagn. Virol
, vol.10
, Issue.2-3
, pp. 157-162
-
-
Gale Jr, M.J.1
Korth, M.J.2
Katze, M.G.3
-
103
-
-
0343924357
-
Evidence that hepatitis C virus resistance to interferon is mediated through repression of the PKR protein kinase by the nonstructural 5A protein
-
Gale MJ Jr, Korth MJ, Tang NM et al. Evidence that hepatitis C virus resistance to interferon is mediated through repression of the PKR protein kinase by the nonstructural 5A protein. Virology 230(2), 217-227 (1997).
-
(1997)
Virology
, vol.230
, Issue.2
, pp. 217-227
-
-
Gale Jr, M.J.1
Korth, M.J.2
Tang, N.M.3
-
104
-
-
13944263525
-
Mutational analysis of hepatitis C virus nonstructural protein 5A: Potential role of differential phosphorylation in RNA replication and identification of a genetically flexible domain
-
Appel N, Pietschmann T, Bartenschlager R. Mutational analysis of hepatitis C virus nonstructural protein 5A: potential role of differential phosphorylation in RNA replication and identification of a genetically flexible domain. J. Virol. 79(5), 3187-3194 (2005).
-
(2005)
J. Virol
, vol.79
, Issue.5
, pp. 3187-3194
-
-
Appel, N.1
Pietschmann, T.2
Bartenschlager, R.3
-
105
-
-
42949145532
-
-
Tellinghuisen TL, Foss KL, Treadaway J. Regulation of hepatitis C virion production via phosphorylation of the NS5A protein. PLoS Pathog. 4(3), e1000032 (2008).
-
Tellinghuisen TL, Foss KL, Treadaway J. Regulation of hepatitis C virion production via phosphorylation of the NS5A protein. PLoS Pathog. 4(3), e1000032 (2008).
-
-
-
-
106
-
-
42949130180
-
-
Appel N, Zayas M, Miller S et al. Essential role of domain III of nonstructural protein 5A for hepatitis C virus infectious particle assembly. PLoS Pathog. 4(3), e1000035 (2008).
-
Appel N, Zayas M, Miller S et al. Essential role of domain III of nonstructural protein 5A for hepatitis C virus infectious particle assembly. PLoS Pathog. 4(3), e1000035 (2008).
-
-
-
-
107
-
-
0036891849
-
The hepatitis C virus RNA-dependent RNA polymerase membrane insertion sequence is a transmembrane segment
-
Ivashkina N, Wolk B, Lohmann V et al. The hepatitis C virus RNA-dependent RNA polymerase membrane insertion sequence is a transmembrane segment. J. Virol. 76(24), 13088-13093 (2002).
-
(2002)
J. Virol
, vol.76
, Issue.24
, pp. 13088-13093
-
-
Ivashkina, N.1
Wolk, B.2
Lohmann, V.3
-
108
-
-
0035941344
-
Determinants for membrane association of the hepatitis C virus RNA-dependent RNA polymerase
-
Schmidt-Mende J, Bieck E, Hugle T et al. Determinants for membrane association of the hepatitis C virus RNA-dependent RNA polymerase. J. Biol. Chem. 276(47), 44052-44063 (2001).
-
(2001)
J. Biol. Chem
, vol.276
, Issue.47
, pp. 44052-44063
-
-
Schmidt-Mende, J.1
Bieck, E.2
Hugle, T.3
-
109
-
-
11144246127
-
Novel insights into hepatitis C virus replication and persistence
-
Bartenschlager R, Frese M, Pietschmann T. Novel insights into hepatitis C virus replication and persistence. Adv. Virus Res. 63, 71-180 (2004).
-
(2004)
Adv. Virus Res
, vol.63
, pp. 71-180
-
-
Bartenschlager, R.1
Frese, M.2
Pietschmann, T.3
-
110
-
-
0033539482
-
Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus
-
Bressanelli S, Tomei L, Roussel A et al. Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus. Proc. Natl Acad. Sci. USA 96(23), 13034-13039 (1999).
-
(1999)
Proc. Natl Acad. Sci. USA
, vol.96
, Issue.23
, pp. 13034-13039
-
-
Bressanelli, S.1
Tomei, L.2
Roussel, A.3
-
111
-
-
0032876683
-
Crystal structure of the RNA-dependent RNA polymerase from hepatitis C virus reveals a fully encircled active site
-
Lesburg CA, Cable MB, Ferrari E, Hong Z, Mannarino AF, Weber PC. Crystal structure of the RNA-dependent RNA polymerase from hepatitis C virus reveals a fully encircled active site. Nat. Struct. Biol. 6(10), 937-943 (1999).
-
(1999)
Nat. Struct. Biol
, vol.6
, Issue.10
, pp. 937-943
-
-
Lesburg, C.A.1
Cable, M.B.2
Ferrari, E.3
Hong, Z.4
Mannarino, A.F.5
Weber, P.C.6
-
112
-
-
7044228006
-
The pathway of HCV IRES-mediated translation initiation
-
Otto GA, Puglisi JD. The pathway of HCV IRES-mediated translation initiation. Cell 119(3), 369-380 (2004).
-
(2004)
Cell
, vol.119
, Issue.3
, pp. 369-380
-
-
Otto, G.A.1
Puglisi, J.D.2
-
113
-
-
0035912725
-
Molecular mechanisms of translation initiation in eukaryotes
-
Pestova TV, Kolupaeva VG, Lomakin IB et al. Molecular mechanisms of translation initiation in eukaryotes. Proc. Natl Acad. Sci. USA 98(13), 7029-7036 (2001).
-
(2001)
Proc. Natl Acad. Sci. USA
, vol.98
, Issue.13
, pp. 7029-7036
-
-
Pestova, T.V.1
Kolupaeva, V.G.2
Lomakin, I.B.3
-
114
-
-
10344243545
-
Coordinated assembly of human translation initiation complexes by the hepatitis C virus internal ribosome entry site RNA
-
Ji H, Fraser CS, Yu Y, Leary J, Doudna JA. Coordinated assembly of human translation initiation complexes by the hepatitis C virus internal ribosome entry site RNA. Proc. Natl Acad. Sci. USA 101(49), 16990-16995 (2004).
-
(2004)
Proc. Natl Acad. Sci. USA
, vol.101
, Issue.49
, pp. 16990-16995
-
-
Ji, H.1
Fraser, C.S.2
Yu, Y.3
Leary, J.4
Doudna, J.A.5
-
115
-
-
33748933183
-
Hepatitis C virus entry: Molecular biology and clinical implications
-
Barth H, Liang TJ, Baumert TF. Hepatitis C virus entry: molecular biology and clinical implications. Hepatology 44(3), 527-535 (2006).
-
(2006)
Hepatology
, vol.44
, Issue.3
, pp. 527-535
-
-
Barth, H.1
Liang, T.J.2
Baumert, T.F.3
-
116
-
-
34147219730
-
Claudin-1 is a hepatitis C virus co-receptor required for a late step in entry
-
Evans MJ, von Hahn T, Tscherne DM et al. Claudin-1 is a hepatitis C virus co-receptor required for a late step in entry. Nature 446(7137), 801-805 (2007).
-
(2007)
Nature
, vol.446
, Issue.7137
, pp. 801-805
-
-
Evans, M.J.1
von Hahn, T.2
Tscherne, D.M.3
-
117
-
-
0031852042
-
Treating histologically mild chronic hepatitis C: Monotherapy, combination therapy, or tincture of time?
-
Levine RA. Treating histologically mild chronic hepatitis C: monotherapy, combination therapy, or tincture of time? Ann. Intern. Med. 129(4), 323-326 (1998).
-
(1998)
Ann. Intern. Med
, vol.129
, Issue.4
, pp. 323-326
-
-
Levine, R.A.1
-
118
-
-
0030852143
-
Management of chronic hepatitis C: Clinical audit of biopsy based management algorithm
-
Foster GR, Goldin RD, Main J, Murray-Lyon I, Hargreaves S, Thomas HC. Management of chronic hepatitis C: clinical audit of biopsy based management algorithm. BMJ 315(7106), 453-458 (1997).
-
(1997)
BMJ
, vol.315
, Issue.7106
, pp. 453-458
-
-
Foster, G.R.1
Goldin, R.D.2
Main, J.3
Murray-Lyon, I.4
Hargreaves, S.5
Thomas, H.C.6
-
119
-
-
0034619548
-
Watchful waiting with periodic liver biopsy versus immediate empirical therapy for histologically mild chronic hepatitis C. A cost-effectiveness analysis
-
Wong JB, Koff RS. Watchful waiting with periodic liver biopsy versus immediate empirical therapy for histologically mild chronic hepatitis C. A cost-effectiveness analysis. Ann. Intern. Med. 133(9), 665-675 (2000).
-
(2000)
Ann. Intern. Med
, vol.133
, Issue.9
, pp. 665-675
-
-
Wong, J.B.1
Koff, R.S.2
-
120
-
-
0024981607
-
Recombinant interferon α therapy for chronic hepatitis C. A randomized, double-blind, placebo-controlled trial
-
Di Bisceglie AM, Martin P, Kassianides C et al. Recombinant interferon α therapy for chronic hepatitis C. A randomized, double-blind, placebo-controlled trial. N. Engl. J. Med. 321(22), 1506-1510 (1989).
-
(1989)
N. Engl. J. Med
, vol.321
, Issue.22
, pp. 1506-1510
-
-
Di Bisceglie, A.M.1
Martin, P.2
Kassianides, C.3
-
121
-
-
0024368522
-
Treatment of chronic hepatitis C with recombinant interferon α. A multicenter randomized, controlled trial. Hepatitis Interventional Therapy Group
-
Davis GL, Balart LA, Schiff ER et al. Treatment of chronic hepatitis C with recombinant interferon α. A multicenter randomized, controlled trial. Hepatitis Interventional Therapy Group. N. Engl. J. Med. 321(22), 1501-1506 (1989).
-
(1989)
N. Engl. J. Med
, vol.321
, Issue.22
, pp. 1501-1506
-
-
Davis, G.L.1
Balart, L.A.2
Schiff, E.R.3
-
122
-
-
0029833829
-
Meta-analysis of interferon randomized trials in the treatment of viral hepatitis C: Effects of dose and duration
-
Poynard T, Leroy V, Cohard M et al. Meta-analysis of interferon randomized trials in the treatment of viral hepatitis C: effects of dose and duration. Hepatology 24(4), 778-789 (1996).
-
(1996)
Hepatology
, vol.24
, Issue.4
, pp. 778-789
-
-
Poynard, T.1
Leroy, V.2
Cohard, M.3
-
123
-
-
0032547944
-
Interferon α-2b alone or in combination with ribavirin for the treatment of relapse of chronic hepatitis C. International Hepatitis Interventional Therapy Group
-
Davis GL, Esteban-Mur R, Rustgi V et al. Interferon α-2b alone or in combination with ribavirin for the treatment of relapse of chronic hepatitis C. International Hepatitis Interventional Therapy Group. N. Engl. J. Med. 339(21), 1493-1499 (1998).
-
(1998)
N. Engl. J. Med
, vol.339
, Issue.21
, pp. 1493-1499
-
-
Davis, G.L.1
Esteban-Mur, R.2
Rustgi, V.3
-
124
-
-
0032585237
-
Randomised trial of interferon α2b plus ribavirin for 48 weeks or for 24 weeks versus interferon α2b plus placebo for 48 weeks for treatment of chronic infection with hepatitis C virus. International Hepatitis Interventional Therapy Group (IHIT)
-
Poynard T, Marcellin P, Lee SS et al. Randomised trial of interferon α2b plus ribavirin for 48 weeks or for 24 weeks versus interferon α2b plus placebo for 48 weeks for treatment of chronic infection with hepatitis C virus. International Hepatitis Interventional Therapy Group (IHIT). Lancet 352(9138), 1426-1432 (1998).
-
(1998)
Lancet
, vol.352
, Issue.9138
, pp. 1426-1432
-
-
Poynard, T.1
Marcellin, P.2
Lee, S.S.3
-
125
-
-
0033766167
-
Impact of interferon α-2b and ribavirin on progression of liver fibrosis in patients with chronic hepatitis C
-
Poynard T, McHutchison J, Davis GL et al. Impact of interferon α-2b and ribavirin on progression of liver fibrosis in patients with chronic hepatitis C. Hepatology 32(5), 1131-1137 (2000).
-
(2000)
Hepatology
, vol.32
, Issue.5
, pp. 1131-1137
-
-
Poynard, T.1
McHutchison, J.2
Davis, G.L.3
-
126
-
-
0032754340
-
Use of interferon for prevention of hepatocellular carcinoma in cirrhotic patients with hepatitis B or hepatitis C virus infection
-
Baffis V, Shrier I, Sherker AH, Szilagyi A. Use of interferon for prevention of hepatocellular carcinoma in cirrhotic patients with hepatitis B or hepatitis C virus infection. Ann. Intern. Med. 131(9), 696-701 (1999).
-
(1999)
Ann. Intern. Med
, vol.131
, Issue.9
, pp. 696-701
-
-
Baffis, V.1
Shrier, I.2
Sherker, A.H.3
Szilagyi, A.4
-
127
-
-
0029682112
-
Preferential virological response to interferon-α2a in patients with chronic hepatitis C infected by virus genotype 3a and exhibiting a low γ-GT/ALT ratio
-
Mihm S, Hartmann H, Fayyazi A, Ramadori G. Preferential virological response to interferon-α2a in patients with chronic hepatitis C infected by virus genotype 3a and exhibiting a low γ-GT/ALT ratio. Dig. Dis. Sci. 41(6), 1256-1264 (1996).
-
(1996)
Dig. Dis. Sci
, vol.41
, Issue.6
, pp. 1256-1264
-
-
Mihm, S.1
Hartmann, H.2
Fayyazi, A.3
Ramadori, G.4
-
128
-
-
0033001639
-
Ratio of serum γ-GT/ALT rather than ISDR variability is predictive for initial virological response to IFN-α in chronic HCV infection
-
Mihm S, Monazahian M, Grethe S, Fechner C, Ramadori G, Thomssen R. Ratio of serum γ-GT/ALT rather than ISDR variability is predictive for initial virological response to IFN-α in chronic HCV infection. J. Med. Virol. 58(3), 227-234 (1999).
-
(1999)
J. Med. Virol
, vol.58
, Issue.3
, pp. 227-234
-
-
Mihm, S.1
Monazahian, M.2
Grethe, S.3
Fechner, C.4
Ramadori, G.5
Thomssen, R.6
-
129
-
-
0031658197
-
Mutations in the interferon-sensitivity determining region of hepatitis C virus and transcriptional activity of the nonstructural region 5A protein
-
Fukuma T, Enomoto N, Marumo F, Sato C. Mutations in the interferon-sensitivity determining region of hepatitis C virus and transcriptional activity of the nonstructural region 5A protein. Hepatology 28(4), 1147-1153 (1998).
-
(1998)
Hepatology
, vol.28
, Issue.4
, pp. 1147-1153
-
-
Fukuma, T.1
Enomoto, N.2
Marumo, F.3
Sato, C.4
-
130
-
-
0034080813
-
Lack of clinical evidence for involvement of hepatitis C virus interferon-α sensitivity-determining region variability in RNA-dependent protein kinase-mediated cellular antiviral responses
-
Mihm S, Monazahian M, Grethe S, Meier V, Thomssen R, Ramadori G. Lack of clinical evidence for involvement of hepatitis C virus interferon-α sensitivity-determining region variability in RNA-dependent protein kinase-mediated cellular antiviral responses. J. Med. Virol. 61(1), 29-36 (2000).
-
(2000)
J. Med. Virol
, vol.61
, Issue.1
, pp. 29-36
-
-
Mihm, S.1
Monazahian, M.2
Grethe, S.3
Meier, V.4
Thomssen, R.5
Ramadori, G.6
-
131
-
-
33747056830
-
Interferon regulatory factor-1 promoter polymorphism and the outcome of hepatitis C virus infection
-
Wietzke-Braun P, Maouzi AB, Manhardt LB, Bickeboller H, Ramadori G, Mihm S. Interferon regulatory factor-1 promoter polymorphism and the outcome of hepatitis C virus infection. Eur. J. Gastroenterol. Hepatol. 18(9), 991-997 (2006).
-
(2006)
Eur. J. Gastroenterol. Hepatol
, vol.18
, Issue.9
, pp. 991-997
-
-
Wietzke-Braun, P.1
Maouzi, A.B.2
Manhardt, L.B.3
Bickeboller, H.4
Ramadori, G.5
Mihm, S.6
-
132
-
-
34548522582
-
Spontaneous elimination of hepatitis C virus infection: A retrospective study on demographic, clinical, and serological correlates
-
Wietzke-Braun P, Manhardt LB, Rosenberger A, Uy A, Ramadori G, Mihm S. Spontaneous elimination of hepatitis C virus infection: a retrospective study on demographic, clinical, and serological correlates. World J. Gastroenterol. 13(31), 4224-4229 (2007).
-
(2007)
World J. Gastroenterol
, vol.13
, Issue.31
, pp. 4224-4229
-
-
Wietzke-Braun, P.1
Manhardt, L.B.2
Rosenberger, A.3
Uy, A.4
Ramadori, G.5
Mihm, S.6
-
133
-
-
0032773473
-
Clearance of HCV RNA in a chronic hepatitis C virus-infected patient during acute hepatitis B virus superinfection
-
Wietzke P, Schott P, Braun F, Mihm S, Ramadori G. Clearance of HCV RNA in a chronic hepatitis C virus-infected patient during acute hepatitis B virus superinfection. Liver 19(4), 348-353 (1999).
-
(1999)
Liver
, vol.19
, Issue.4
, pp. 348-353
-
-
Wietzke, P.1
Schott, P.2
Braun, F.3
Mihm, S.4
Ramadori, G.5
-
134
-
-
33645992473
-
Extended treatment duration for hepatitis C virus type 1: Comparing 48 versus 72 weeks of peginterferon-α-2a plus ribavirin
-
Berg T, von Wagner M, Nasser S et al. Extended treatment duration for hepatitis C virus type 1: comparing 48 versus 72 weeks of peginterferon-α-2a plus ribavirin. Gastroenterology 130(4), 1086-1097 (2006).
-
(2006)
Gastroenterology
, vol.130
, Issue.4
, pp. 1086-1097
-
-
Berg, T.1
von Wagner, M.2
Nasser, S.3
-
135
-
-
33746564989
-
2a plus ribavirin for 48 versus 72 weeks in patients with detectable hepatitis C virus RNA at week 4 of treatment
-
2a plus ribavirin for 48 versus 72 weeks in patients with detectable hepatitis C virus RNA at week 4 of treatment. Gastroenterology 131(2), 451-460 (2006).
-
(2006)
Gastroenterology
, vol.131
, Issue.2
, pp. 451-460
-
-
Sanchez-Tapias, J.M.1
Diago, M.2
Escartin, P.3
-
136
-
-
28844451934
-
Efficacy of 24 weeks treatment with peginterferon α-2b plus ribavirin in patients with chronic hepatitis C infected with genotype 1 and low pretreatment viremia
-
Zeuzem S, Buti M, Ferenci P et al. Efficacy of 24 weeks treatment with peginterferon α-2b plus ribavirin in patients with chronic hepatitis C infected with genotype 1 and low pretreatment viremia. J. Hepatol. 44(1), 97-103 (2006).
-
(2006)
J. Hepatol
, vol.44
, Issue.1
, pp. 97-103
-
-
Zeuzem, S.1
Buti, M.2
Ferenci, P.3
-
137
-
-
20544443172
-
Peginterferon α-2b and ribavirin for 12 vs. 24 weeks in HCV genotype 2 or 3
-
Mangia A, Santoro R, Minerva N et al. Peginterferon α-2b and ribavirin for 12 vs. 24 weeks in HCV genotype 2 or 3. N. Engl. J. Med. 352(25), 2609-2617 (2005).
-
(2005)
N. Engl. J. Med
, vol.352
, Issue.25
, pp. 2609-2617
-
-
Mangia, A.1
Santoro, R.2
Minerva, N.3
-
138
-
-
23244457832
-
Peginterferon-α-2a (40KD) and ribavirin for 16 or 24 weeks in patients with genotype 2 or 3 chronic hepatitis C
-
von Wagner M, Huber M, Berg T et al. Peginterferon-α-2a (40KD) and ribavirin for 16 or 24 weeks in patients with genotype 2 or 3 chronic hepatitis C. Gastroenterology 129(2), 522-527 (2005).
-
(2005)
Gastroenterology
, vol.129
, Issue.2
, pp. 522-527
-
-
von Wagner, M.1
Huber, M.2
Berg, T.3
-
139
-
-
34447318385
-
Peginterferon α-2a and ribavirin for 16 or 24 weeks in HCV genotype 2 or 3
-
Shiffman ML, Suter F, Bacon BR et al. Peginterferon α-2a and ribavirin for 16 or 24 weeks in HCV genotype 2 or 3. N. Engl. J. Med. 357(2), 124-134 (2007).
-
(2007)
N. Engl. J. Med
, vol.357
, Issue.2
, pp. 124-134
-
-
Shiffman, M.L.1
Suter, F.2
Bacon, B.R.3
-
140
-
-
2442683905
-
Peginterferon α-2b plus ribavirin for treatment of chronic hepatitis C in previously untreated patients infected with HCV genotypes 2 or 3
-
Zeuzem S, Hultcrantz R, Bourliere M et al. Peginterferon α-2b plus ribavirin for treatment of chronic hepatitis C in previously untreated patients infected with HCV genotypes 2 or 3. J. Hepatol. 40(6), 993-999 (2004).
-
(2004)
J. Hepatol
, vol.40
, Issue.6
, pp. 993-999
-
-
Zeuzem, S.1
Hultcrantz, R.2
Bourliere, M.3
-
141
-
-
57349116772
-
Prolonged therapy of advanced chronic hepatitis C with low-dose peginterferon
-
Di Bisceglie AM, Shiffman ML, Everson GT et al. Prolonged therapy of advanced chronic hepatitis C with low-dose peginterferon. N. Engl. J. Med. 359(23), 2429-2441 (2008).
-
(2008)
N. Engl. J. Med
, vol.359
, Issue.23
, pp. 2429-2441
-
-
Di Bisceglie, A.M.1
Shiffman, M.L.2
Everson, G.T.3
-
142
-
-
36348981708
-
Peginterferon α-2b and weight-based or flat-dose ribavirin in chronic hepatitis C patients: A randomized trial
-
Jacobson IM, Brown RS Jr, Freilich B et al. Peginterferon α-2b and weight-based or flat-dose ribavirin in chronic hepatitis C patients: a randomized trial. Hepatology 46(4), 971-981 (2007).
-
(2007)
Hepatology
, vol.46
, Issue.4
, pp. 971-981
-
-
Jacobson, I.M.1
Brown Jr, R.S.2
Freilich, B.3
-
143
-
-
1542378867
-
Peginterferon-α2a and ribavirin combination therapy in chronic hepatitis C: A randomized study of treatment duration and ribavirin dose
-
Hadziyannis SJ, Sette H Jr, Morgan TR et al. Peginterferon-α2a and ribavirin combination therapy in chronic hepatitis C: a randomized study of treatment duration and ribavirin dose. Ann. Intern. Med. 140(5), 346-355 (2004).
-
(2004)
Ann. Intern. Med
, vol.140
, Issue.5
, pp. 346-355
-
-
Hadziyannis, S.J.1
Sette Jr, H.2
Morgan, T.R.3
-
144
-
-
33644547392
-
Antiviral therapy for chronic hepatitis C: Past, present, and future
-
Hayashi N, Takehara T. Antiviral therapy for chronic hepatitis C: past, present, and future. J. Gastroenterol. 41(1), 17-27 (2006).
-
(2006)
J. Gastroenterol
, vol.41
, Issue.1
, pp. 17-27
-
-
Hayashi, N.1
Takehara, T.2
-
145
-
-
0032417696
-
Identification of genes differentially regulated by interferon α, β, or γ using oligonucleotide arrays
-
Der SD, Zhou A, Williams BR, Silverman RH. Identification of genes differentially regulated by interferon α, β, or γ using oligonucleotide arrays. Proc. Natl Acad. Sci. USA 95(26), 15623-15628 (1998).
-
(1998)
Proc. Natl Acad. Sci. USA
, vol.95
, Issue.26
, pp. 15623-15628
-
-
SD, D.1
Zhou, A.2
Williams, B.R.3
Silverman, R.H.4
-
146
-
-
0032036611
-
Mx proteins: Mediators of innate resistance to RNA. viruses
-
Haller O, Frese M, Kochs G. Mx proteins: mediators of innate resistance to RNA. viruses. Rev. Sci. Tech. 17(1), 220-230 (1998).
-
(1998)
Rev. Sci. Tech
, vol.17
, Issue.1
, pp. 220-230
-
-
Haller, O.1
Frese, M.2
Kochs, G.3
-
147
-
-
33646377870
-
Interferon signalling network in innate defence
-
Takaoka A, Yanai H. Interferon signalling network in innate defence. Cell. Microbiol. 8(6), 907-922 (2006).
-
(2006)
Cell. Microbiol
, vol.8
, Issue.6
, pp. 907-922
-
-
Takaoka, A.1
Yanai, H.2
-
148
-
-
0035065277
-
Interferon-α inhibits hepatitis C virus subgenomic RNA replication by an MxA-independent pathway
-
Frese M, Pietschmann T, Moradpour D, Haller O, Bartenschlager R. Interferon-α inhibits hepatitis C virus subgenomic RNA replication by an MxA-independent pathway. J. Gen. Virol. 82(Pt 4), 723-733 (2001).
-
(2001)
J. Gen. Virol
, vol.82
, Issue.PART 4
, pp. 723-733
-
-
Frese, M.1
Pietschmann, T.2
Moradpour, D.3
Haller, O.4
Bartenschlager, R.5
-
149
-
-
0033804119
-
mxA gene expression in peripheral blood mononuclear cells from patients infected chronically with hepatitis C virus treated with interferon-α
-
Meier V, Mihm S, Ramadori G. mxA gene expression in peripheral blood mononuclear cells from patients infected chronically with hepatitis C virus treated with interferon-α. J. Med. Virol. 62(3), 318-326 (2000).
-
(2000)
J. Med. Virol
, vol.62
, Issue.3
, pp. 318-326
-
-
Meier, V.1
Mihm, S.2
Ramadori, G.3
-
150
-
-
36348960622
-
Hepatic gene expression during treatment with peginterferon and ribavirin: Identifying molecular pathways for treatment response
-
Feld JJ, Nanda S, Huang Y et al. Hepatic gene expression during treatment with peginterferon and ribavirin: identifying molecular pathways for treatment response. Hepatology 46(5), 1548-1563 (2007).
-
(2007)
Hepatology
, vol.46
, Issue.5
, pp. 1548-1563
-
-
Feld, J.J.1
Nanda, S.2
Huang, Y.3
-
152
-
-
54749105112
-
Interferon-α therapy does not modulate hepatic expression of classical type I interferon inducible genes
-
Meier V, Mihm S, Ramadori G. Interferon-α therapy does not modulate hepatic expression of classical type I interferon inducible genes. J. Med. Virol. 80(11), 1912-1918 (2008).
-
(2008)
J. Med. Virol
, vol.80
, Issue.11
, pp. 1912-1918
-
-
Meier, V.1
Mihm, S.2
Ramadori, G.3
-
153
-
-
33646573998
-
Genomic response to interferon-α in chimpanzees: Implications of rapid downregulation for hepatitis C kinetics
-
Lanford RE, Guerra B, Lee H, Chavez D, Brasky KM, Bigger CB. Genomic response to interferon-α in chimpanzees: implications of rapid downregulation for hepatitis C kinetics. Hepatology 43(5), 961-972 (2006).
-
(2006)
Hepatology
, vol.43
, Issue.5
, pp. 961-972
-
-
Lanford, R.E.1
Guerra, B.2
Lee, H.3
Chavez, D.4
Brasky, K.M.5
Bigger, C.B.6
-
154
-
-
36348963131
-
Lack of response to exogenous interferon-α in the liver of chimpanzees chronically infected with hepatitis C virus
-
Lanford RE, Guerra B, Bigger CB, Lee H, Chavez D, Brasky KM. Lack of response to exogenous interferon-α in the liver of chimpanzees chronically infected with hepatitis C virus. Hepatology 46(4), 999-1008 (2007).
-
(2007)
Hepatology
, vol.46
, Issue.4
, pp. 999-1008
-
-
Lanford, R.E.1
Guerra, B.2
Bigger, C.B.3
Lee, H.4
Chavez, D.5
Brasky, K.M.6
-
155
-
-
4344705233
-
Interferon type I gene expression in chronic hepatitis C
-
Mihm S, Frese M, Meier V et al. Interferon type I gene expression in chronic hepatitis C. Lab. Invest. 84(9), 1148-1159 (2004).
-
(2004)
Lab. Invest
, vol.84
, Issue.9
, pp. 1148-1159
-
-
Mihm, S.1
Frese, M.2
Meier, V.3
-
156
-
-
0035138173
-
Enhanced expression of interferon-regulated genes in the liver of patients with chronic hepatitis C virus infection: Detection by suppression-subtractive hybridization
-
Patzwahl R, Meier V, Ramadori G, Mihm S. Enhanced expression of interferon-regulated genes in the liver of patients with chronic hepatitis C virus infection: detection by suppression-subtractive hybridization. J. Virol. 75(3), 1332-1338 (2001).
-
(2001)
J. Virol
, vol.75
, Issue.3
, pp. 1332-1338
-
-
Patzwahl, R.1
Meier, V.2
Ramadori, G.3
Mihm, S.4
-
157
-
-
0036172292
-
Insights into the pathobiology of hepatitis C virus-associated cirrhosis: Analysis of intrahepatic differential gene expression
-
Shackel NA, McGuinness PH, Abbott CA, Gorrell MD, McCaughan GW. Insights into the pathobiology of hepatitis C virus-associated cirrhosis: analysis of intrahepatic differential gene expression. Am. J. Pathol. 160(2), 641-654 (2002).
-
(2002)
Am. J. Pathol
, vol.160
, Issue.2
, pp. 641-654
-
-
Shackel, N.A.1
McGuinness, P.H.2
Abbott, C.A.3
Gorrell, M.D.4
McCaughan, G.W.5
-
158
-
-
0242584810
-
Upregulation of endogenous intrahepatic interferon stimulated genes during chronic hepatitis C virus infection
-
MacQuillan GC, Mamotte C, Reed WD, Jeffrey GP, Allan JE. Upregulation of endogenous intrahepatic interferon stimulated genes during chronic hepatitis C virus infection. J. Med. Virol. 70(2), 219-227 (2003).
-
(2003)
J. Med. Virol
, vol.70
, Issue.2
, pp. 219-227
-
-
MacQuillan, G.C.1
Mamotte, C.2
Reed, W.D.3
Jeffrey, G.P.4
Allan, J.E.5
-
159
-
-
0036828810
-
Treatment of patients with hepatitis C and cirrhosis
-
Wright TL. Treatment of patients with hepatitis C and cirrhosis. Hepatology 36(5 Suppl. 1), S185-S194 (2002).
-
(2002)
Hepatology
, vol.36
, Issue.5 SUPPL. 1
-
-
Wright, T.L.1
-
160
-
-
33947360829
-
Sustained virological response to interferon-α is associated with improved outcome in HCV-related cirrhosis: A retrospective study
-
Bruno S, Stroffolini T, Colombo M et al. Sustained virological response to interferon-α is associated with improved outcome in HCV-related cirrhosis: a retrospective study. Hepatology 45(3), 579-587 (2007).
-
(2007)
Hepatology
, vol.45
, Issue.3
, pp. 579-587
-
-
Bruno, S.1
Stroffolini, T.2
Colombo, M.3
-
161
-
-
33745838657
-
Long-term effect of interferon α-2b plus ribavirin therapy on incidence of hepatocellular carcinoma in patients with hepatitis C virus-related cirrhosis
-
Hung CH, Lee CM, Lu SN et al. Long-term effect of interferon α-2b plus ribavirin therapy on incidence of hepatocellular carcinoma in patients with hepatitis C virus-related cirrhosis. J. Viral Hepat. 13(6), 409-414 (2006).
-
(2006)
J. Viral Hepat
, vol.13
, Issue.6
, pp. 409-414
-
-
Hung, C.H.1
Lee, C.M.2
Lu, S.N.3
-
162
-
-
0035061788
-
Interferon and prevention of hepatocellular carcinoma in viral cirrhosis: An evidence-based approach
-
Camma C, Giunta M, Andreone P, Craxi A. Interferon and prevention of hepatocellular carcinoma in viral cirrhosis: an evidence-based approach. J. Hepatol. 34(4), 593-602 (2001).
-
(2001)
J. Hepatol
, vol.34
, Issue.4
, pp. 593-602
-
-
Camma, C.1
Giunta, M.2
Andreone, P.3
Craxi, A.4
-
163
-
-
0035037997
-
Effect of interferon therapy on the development of hepatocellular carcinoma in patients with hepatitis C virus-related cirrhosis: A meta-analysis
-
Papatheodoridis GV, Papadimitropoulos VC, Hadziyannis SJ. Effect of interferon therapy on the development of hepatocellular carcinoma in patients with hepatitis C virus-related cirrhosis: a meta-analysis. Aliment. Pharmacol. Ther. 15(5), 689-698 (2001).
-
(2001)
Aliment. Pharmacol. Ther
, vol.15
, Issue.5
, pp. 689-698
-
-
Papatheodoridis, G.V.1
Papadimitropoulos, V.C.2
Hadziyannis, S.J.3
-
164
-
-
0037222767
-
Spontaneous viral clearance in patients with acute hepatitis C can be predicted by repeated measurements of serum viral load
-
Hofer H, Watkins-Riedel T, Janata O et al. Spontaneous viral clearance in patients with acute hepatitis C can be predicted by repeated measurements of serum viral load. Hepatology 37(1), 60-64 (2003).
-
(2003)
Hepatology
, vol.37
, Issue.1
, pp. 60-64
-
-
Hofer, H.1
Watkins-Riedel, T.2
Janata, O.3
-
165
-
-
0038575483
-
Acute hepatitis C: High rate of both spontaneous and treatment-induced viral clearance
-
Gerlach JT, Diepolder HM, Zachoval R et al. Acute hepatitis C: high rate of both spontaneous and treatment-induced viral clearance. Gastroenterology 125(1), 80-88 (2003).
-
(2003)
Gastroenterology
, vol.125
, Issue.1
, pp. 80-88
-
-
Gerlach, J.T.1
Diepolder, H.M.2
Zachoval, R.3
-
166
-
-
33644857481
-
2b therapy in acute hepatitis C: Impact of onset of therapy on sustained virologic response
-
2b therapy in acute hepatitis C: impact of onset of therapy on sustained virologic response. Gastroenterology 130(3), 632-638 (2006).
-
(2006)
Gastroenterology
, vol.130
, Issue.3
, pp. 632-638
-
-
Kamal, S.M.1
Fouly, A.E.2
Kamel, R.R.3
-
167
-
-
13844270879
-
Efficacy of a 24-week course of PEG-interferon α-2b monotherapy in patients with acute hepatitis C after failure of spontaneous clearance
-
Santantonio T, Fasano M, Sinisi E et al. Efficacy of a 24-week course of PEG-interferon α-2b monotherapy in patients with acute hepatitis C after failure of spontaneous clearance. J. Hepatol. 42(3), 329-333 (2005).
-
(2005)
J. Hepatol
, vol.42
, Issue.3
, pp. 329-333
-
-
Santantonio, T.1
Fasano, M.2
Sinisi, E.3
-
168
-
-
33646562220
-
Duration of peginterferon therapy in acute hepatitis C: A randomized trial
-
Kamal SM, Moustafa KN, Chen J et al. Duration of peginterferon therapy in acute hepatitis C: a randomized trial. Hepatology 43(5), 923-931 (2006).
-
(2006)
Hepatology
, vol.43
, Issue.5
, pp. 923-931
-
-
Kamal, S.M.1
Moustafa, K.N.2
Chen, J.3
-
169
-
-
34548610612
-
Anti-hepatitis C virus activity of albinterferon α-2b in cell culture
-
Liu C, Zhu H, Subramanian GM, Moore PA, Xu Y, Nelson DR. Anti-hepatitis C virus activity of albinterferon α-2b in cell culture. Hepatol. Res. 37(11), 941-947 (2007).
-
(2007)
Hepatol. Res
, vol.37
, Issue.11
, pp. 941-947
-
-
Liu, C.1
Zhu, H.2
Subramanian, G.M.3
Moore, P.A.4
Xu, Y.5
Nelson, D.R.6
-
170
-
-
33644918919
-
A Phase 2 study to evaluate the antiviral activity, safety, and pharmacokinetics of recombinant human albumin - interferon α fusion protein in genotype 1 chronic hepatitis C patients
-
Bain VG, Kaita KD, Yoshida EM et al. A Phase 2 study to evaluate the antiviral activity, safety, and pharmacokinetics of recombinant human albumin - interferon α fusion protein in genotype 1 chronic hepatitis C patients. J. Hepatol. 44(4), 671-678 (2006).
-
(2006)
J. Hepatol
, vol.44
, Issue.4
, pp. 671-678
-
-
Bain, V.G.1
Kaita, K.D.2
Yoshida, E.M.3
-
171
-
-
33644551889
-
A Phase I/II study evaluating escalating doses of recombinant human albumin - interferon-α fusion protein in chronic hepatitis C patients who have failed previous interferon-α-based therapy
-
Balan V, Nelson DR, Sulkowski MS et al. A Phase I/II study evaluating escalating doses of recombinant human albumin - interferon-α fusion protein in chronic hepatitis C patients who have failed previous interferon-α-based therapy. Antivi. Ther. 11(1), 35-45 (2006).
-
(2006)
Antivi. Ther
, vol.11
, Issue.1
, pp. 35-45
-
-
Balan, V.1
Nelson, D.R.2
Sulkowski, M.S.3
-
172
-
-
49649089488
-
Albinterferon α-2b dosed every two or four weeks in interferon-naive patients with genotype 1 chronic hepatitis C
-
Zeuzem S, Yoshida EM, Benhamou Y et al. Albinterferon α-2b dosed every two or four weeks in interferon-naive patients with genotype 1 chronic hepatitis C. Hepatology 48(2), 407-417 (2008).
-
(2008)
Hepatology
, vol.48
, Issue.2
, pp. 407-417
-
-
Zeuzem, S.1
Yoshida, E.M.2
Benhamou, Y.3
-
173
-
-
44749094657
-
Safety and antiviral activity of albinterferon α-2b dosed every four weeks in genotype 2/3 chronic hepatitis C patients
-
Bain VG, Kaita KD, Marotta P et al. Safety and antiviral activity of albinterferon α-2b dosed every four weeks in genotype 2/3 chronic hepatitis C patients. Clin. Gastroenterol. Hepatol. 6(6), 701-706 (2008).
-
(2008)
Clin. Gastroenterol. Hepatol
, vol.6
, Issue.6
, pp. 701-706
-
-
Bain, V.G.1
Kaita, K.D.2
Marotta, P.3
-
174
-
-
58849122392
-
Safety and antiviral activity of albinterferon α-2b in prior interferon nonresponders with chronic hepatitis C
-
Nelson DR, Rustgi V, Balan V et al. Safety and antiviral activity of albinterferon α-2b in prior interferon nonresponders with chronic hepatitis C. Clin. Gastroenterol. Hepatol. 7(2), 212-218 (2009).
-
(2009)
Clin. Gastroenterol. Hepatol
, vol.7
, Issue.2
, pp. 212-218
-
-
Nelson, D.R.1
Rustgi, V.2
Balan, V.3
-
175
-
-
35748939037
-
Phase 2 study of ω interferon alone or in combination with ribavirin in subjects with chronic hepatitis C genotype-1 infection
-
S
-
Novozhenov V, Zakharova N, Vinogradova E et al. Phase 2 study of ω interferon alone or in combination with ribavirin in subjects with chronic hepatitis C genotype-1 infection. J. Hepatol.
-
(2007)
J. Hepatol
, vol.46
, Issue.SUPPL. 1
, pp. 8
-
-
Novozhenov, V.1
Zakharova, N.2
Vinogradova, E.3
-
176
-
-
39449113296
-
Novel controlled-release Lemna-derived IFN-α2b (Locteron): Pharmacokinetics, pharmacodynamics, and tolerability in a Phase I clinical trial
-
De Leede LG, Humphries JE, Bechet AC, Van Hoogdalem EJ, Verrijk R, Spencer DG. Novel controlled-release Lemna-derived IFN-α2b (Locteron): pharmacokinetics, pharmacodynamics, and tolerability in a Phase I clinical trial. J. Interferon Cytokine Res. 28(2), 113-122 (2008).
-
(2008)
J. Interferon Cytokine Res
, vol.28
, Issue.2
, pp. 113-122
-
-
De Leede, L.G.1
Humphries, J.E.2
Bechet, A.C.3
Van Hoogdalem, E.J.4
Verrijk, R.5
Spencer, D.G.6
-
177
-
-
0141928585
-
Ribavirin, viramidine and adenosine-deaminase-catalysed drug activation: Implication for nucleoside prodrug design
-
Wu JZ, Lin CC, Hong Z. Ribavirin, viramidine and adenosine-deaminase-catalysed drug activation: implication for nucleoside prodrug design. J. Antimicrob. Chemother. 52(4), 543-546 (2003).
-
(2003)
J. Antimicrob. Chemother
, vol.52
, Issue.4
, pp. 543-546
-
-
Wu, J.Z.1
Lin, C.C.2
Hong, Z.3
-
178
-
-
0037228456
-
Activation and deactivation of a broad-spectrum antiviral drug by a single enzyme: Adenosine deaminase catalyzes two consecutive deamination reactions
-
Wu JZ, Walker H, Lau JY, Hong Z. Activation and deactivation of a broad-spectrum antiviral drug by a single enzyme: adenosine deaminase catalyzes two consecutive deamination reactions. Antimicrob. Agents Chemother. 47(1), 426-431 (2003).
-
(2003)
Antimicrob. Agents Chemother
, vol.47
, Issue.1
, pp. 426-431
-
-
Wu, J.Z.1
Walker, H.2
Lau, J.Y.3
Hong, Z.4
-
180
-
-
34249309613
-
Virological response and safety outcomes in therapy-naive patients treated for chronic hepatitis C with taribavirin or ribavirin in combination with pegylated interferon α-2a: A randomized, Phase 2 study
-
Gish RG, Arora S, Rajender Reddy K et al. Virological response and safety outcomes in therapy-naive patients treated for chronic hepatitis C with taribavirin or ribavirin in combination with pegylated interferon α-2a: a randomized, Phase 2 study. J. Hepatol. 47(1), 51-59 (2007).
-
(2007)
J. Hepatol
, vol.47
, Issue.1
, pp. 51-59
-
-
Gish, R.G.1
Arora, S.2
Rajender Reddy, K.3
-
181
-
-
65549156843
-
Taribavirin exposure analysis from a previous Phase 3 trial correlates with Phase 2b weight based dosing interim results
-
Pockros P, Jacobsen IM, Bacon BR et al. Taribavirin exposure analysis from a previous Phase 3 trial correlates with Phase 2b weight based dosing interim results. Hepatology 48 (Suppl. 1), 1857A (2008).
-
(2008)
Hepatology
, vol.48
, Issue.SUPPL. 1
-
-
Pockros, P.1
Jacobsen, I.M.2
Bacon, B.R.3
-
182
-
-
7644232426
-
Short-term antiviral efficacy of BILN 2061, a hepatitis C virus serine protease inhibitor, in hepatitis C genotype 1 patients
-
Hinrichsen H, Benhamou Y, Wedemeyer H et al. Short-term antiviral efficacy of BILN 2061, a hepatitis C virus serine protease inhibitor, in hepatitis C genotype 1 patients. Gastroenterology 127(5), 1347-1355 (2004).
-
(2004)
Gastroenterology
, vol.127
, Issue.5
, pp. 1347-1355
-
-
Hinrichsen, H.1
Benhamou, Y.2
Wedemeyer, H.3
-
183
-
-
2542467813
-
Mutations conferring resistance to a potent hepatitis C virus serine protease inhibitor in vitro
-
Lu L, Pilot-Matias TJ, Stewart KD et al. Mutations conferring resistance to a potent hepatitis C virus serine protease inhibitor in vitro. Antimicrob. Agents Chemother. 48(6), 2260-2266 (2004).
-
(2004)
Antimicrob. Agents Chemother
, vol.48
, Issue.6
, pp. 2260-2266
-
-
Lu, L.1
Pilot-Matias, T.J.2
Stewart, K.D.3
-
184
-
-
33749360242
-
Rapid decline of viral RNA in hepatitis C patients treated with VX-950: A Phase Ib, placebo-controlled, randomized study
-
Reesink HW, Zeuzem S, Weegink CJ et al. Rapid decline of viral RNA in hepatitis C patients treated with VX-950: a Phase Ib, placebo-controlled, randomized study. Gastroenterology 131(4), 997-1002 (2006).
-
(2006)
Gastroenterology
, vol.131
, Issue.4
, pp. 997-1002
-
-
Reesink, H.W.1
Zeuzem, S.2
Weegink, C.J.3
-
185
-
-
34247594930
-
Dynamic hepatitis C virus genotypic and phenotypic changes in patients treated with the protease inhibitor telaprevir
-
Sarrazin C, Kieffer TL, Bartels D et al. Dynamic hepatitis C virus genotypic and phenotypic changes in patients treated with the protease inhibitor telaprevir. Gastroenterology 132(5), 1767-1777 (2007).
-
(2007)
Gastroenterology
, vol.132
, Issue.5
, pp. 1767-1777
-
-
Sarrazin, C.1
Kieffer, T.L.2
Bartels, D.3
-
186
-
-
34247565001
-
Antiviral activity of telaprevir (VX-950) and peginterferon α-2a in patients with hepatitis C
-
Forestier N, Reesink HW, Weegink CJ et al. Antiviral activity of telaprevir (VX-950) and peginterferon α-2a in patients with hepatitis C. Hepatology 46(3), 640-648 (2007).
-
(2007)
Hepatology
, vol.46
, Issue.3
, pp. 640-648
-
-
Forestier, N.1
Reesink, H.W.2
Weegink, C.J.3
-
187
-
-
34250025634
-
Interim results presented at EASL from PROVE 1 clinical trial of investigational drug telaprevir in patients with genotype 1 hepatitis C
-
Les L. Interim results presented at EASL from PROVE 1 clinical trial of investigational drug telaprevir in patients with genotype 1 hepatitis C. Gastroenterology 132(7), 2283-2284 (2007).
-
(2007)
Gastroenterology
, vol.132
, Issue.7
, pp. 2283-2284
-
-
Les, L.1
-
188
-
-
65649112149
-
Phase 2 study of telaprevir administered q8h or q12h with peginterferon-α-2a or - α-2b and ribavirin in treatment-naïve subjects with genotype 1 hepatitis C: Week 4 interim results
-
Forns X, Marcellin P, Goeser T et al. Phase 2 study of telaprevir administered q8h or q12h with peginterferon-α-2a or - α-2b and ribavirin in treatment-naïve subjects with genotype 1 hepatitis C: week 4 interim results. Hepatology 48(Suppl. 1), 1854A (2008).
-
(2008)
Hepatology
, vol.48
, Issue.SUPPL. 1
-
-
Forns, X.1
Marcellin, P.2
Goeser, T.3
-
189
-
-
67650691736
-
A study of telaprevir combined with peginterferon-α-2a and ribavirin in subjects with well-documented non-response or relapse after previous peginterferon-α-2a and ribavirin treatment: Interim analysis
-
Shiffman ML, Berg T, Poordad F et al. A study of telaprevir combined with peginterferon-α-2a and ribavirin in subjects with well-documented non-response or relapse after previous peginterferon-α-2a and ribavirin treatment: interim analysis. Hepatology 48(Suppl. 1), 1852A (2008).
-
(2008)
Hepatology
, vol.48
, Issue.SUPPL. 1
-
-
Shiffman, M.L.1
Berg, T.2
Poordad, F.3
-
190
-
-
62249141788
-
Boceprevir, an NS3 serine protease inhibitor of hepatitis C virus, for the treatment of HCV infection
-
Mederacke I, Wedemeyer H, Manns MP. Boceprevir, an NS3 serine protease inhibitor of hepatitis C virus, for the treatment of HCV infection. Curr. Opin. Investig. Drugs 10(2), 181-189 (2009).
-
(2009)
Curr. Opin. Investig. Drugs
, vol.10
, Issue.2
, pp. 181-189
-
-
Mederacke, I.1
Wedemeyer, H.2
Manns, M.P.3
-
191
-
-
33644639990
-
SCH 503034, a mechanism-based inhibitor of hepatitis C virus NS3 protease, suppresses polyprotein maturation and enhances the antiviral activity of α interferon in replicon cells
-
Malcolm BA, Liu R, Lahser F et al. SCH 503034, a mechanism-based inhibitor of hepatitis C virus NS3 protease, suppresses polyprotein maturation and enhances the antiviral activity of α interferon in replicon cells. Antimicrob. Agents Chemother. 50(3), 1013-1020 (2006).
-
(2006)
Antimicrob. Agents Chemother
, vol.50
, Issue.3
, pp. 1013-1020
-
-
Malcolm, B.A.1
Liu, R.2
Lahser, F.3
-
192
-
-
34247205808
-
SCH 503034, a novel hepatitis C virus protease inhibitor, plus pegylated interferon α-2b for genotype 1 nonresponders
-
Sarrazin C, Rouzier R, Wagner F et al. SCH 503034, a novel hepatitis C virus protease inhibitor, plus pegylated interferon α-2b for genotype 1 nonresponders. Gastroenterology 132(4), 1270-1278 (2007).
-
(2007)
Gastroenterology
, vol.132
, Issue.4
, pp. 1270-1278
-
-
Sarrazin, C.1
Rouzier, R.2
Wagner, F.3
-
193
-
-
65549093455
-
HCV SPRINT-1: Boceprevir plus peginterferon α-2b/ribavirin for treatment of genotype 1 chronic hepatitis C in previously untreated patients
-
Kwo PY, Lawitz E, McCone J et al. HCV SPRINT-1: boceprevir plus peginterferon α-2b/ribavirin for treatment of genotype 1 chronic hepatitis C in previously untreated patients. Hepatology 48(Suppl. 1), LB16 (2008).
-
(2008)
Hepatology
, vol.48
, Issue.SUPPL. 1
-
-
Kwo, P.Y.1
Lawitz, E.2
McCone, J.3
-
194
-
-
57049176125
-
Preclinical characteristics of the HCV NS3/4A protease inhibitor ITMN-191 (R7227)
-
Seiwert SD, Andrews SW, Jiang Y et al. Preclinical characteristics of the HCV NS3/4A protease inhibitor ITMN-191 (R7227). Antimicrob. Agents Chemother. 52(12), 4432-4441 (2008).
-
(2008)
Antimicrob. Agents Chemother
, vol.52
, Issue.12
, pp. 4432-4441
-
-
Seiwert, S.D.1
Andrews, S.W.2
Jiang, Y.3
-
195
-
-
64849101706
-
Inhibition and binding kinetics of the hepatitis C virus NS3 protease inhibitor ITMN-191 reveals tight binding and slow dissociative behavior
-
Rajagopalan R, Misialek S, Stevens S et al. Inhibition and binding kinetics of the hepatitis C virus NS3 protease inhibitor ITMN-191 reveals tight binding and slow dissociative behavior. Biochemistry (2009).
-
(2009)
Biochemistry
-
-
Rajagopalan, R.1
Misialek, S.2
Stevens, S.3
-
196
-
-
59149083999
-
treatment of chronic hepatitis C virus (HCV) genotype 1 patients with the NS3/4A protease inhibitor ITMN-191 leads to rapid reductions in plasma HCV RNA: Results of a Phase 1B multiple ascending dose (MAD) study
-
Forestier N, Larrey D, Guyader D et al. treatment of chronic hepatitis C virus (HCV) genotype 1 patients with the NS3/4A protease inhibitor ITMN-191 leads to rapid reductions in plasma HCV RNA: results of a Phase 1B multiple ascending dose (MAD) study. Hepatology 48(Suppl. 1), 1847A (2008).
-
(2008)
Hepatology
, vol.48
, Issue.SUPPL. 1
-
-
Forestier, N.1
Larrey, D.2
Guyader, D.3
-
197
-
-
77954722551
-
Combination of the NS3/4A protease inhibitor ITMN-191 (R7227) with the active moiety of the NS5b inhibitors R1626 or R7128 enhances replicon clearance and reduces the emergence of drug resistant variants
-
Tan H, Rajyaguru S, Wu T et al. Combination of the NS3/4A protease inhibitor ITMN-191 (R7227) with the active moiety of the NS5b inhibitors R1626 or R7128 enhances replicon clearance and reduces the emergence of drug resistant variants. Hepatology 48(Suppl. 1), 1885A (2008).
-
(2008)
Hepatology
, vol.48
, Issue.SUPPL. 1
-
-
Tan, H.1
Rajyaguru, S.2
Wu, T.3
-
198
-
-
44449099603
-
Selection of replicon variants resistant to ACH-806, a novel hepatitis C virus inhibitor with no cross-resistance to NS3 protease and NS5B polymerase inhibitors
-
Yang W, Zhao Y, Fabrycki J et al. Selection of replicon variants resistant to ACH-806, a novel hepatitis C virus inhibitor with no cross-resistance to NS3 protease and NS5B polymerase inhibitors. Antimicrob. Agents Chemother. 52(6), 2043-2052 (2008).
-
(2008)
Antimicrob. Agents Chemother
, vol.52
, Issue.6
, pp. 2043-2052
-
-
Yang, W.1
Zhao, Y.2
Fabrycki, J.3
-
199
-
-
59149086994
-
Safety and antiviral activity of bi201335, a new HCV NS3 protease inhibitor, in treatment naive patients with chronic hepatitis C genotype-1 infection given as monotherapy and in combination with peginterferon α 2a (P) and ribavirin (R)
-
Manns MP, Bourliere M, Benhamou Y et al. Safety and antiviral activity of bi201335, a new HCV NS3 protease inhibitor, in treatment naive patients with chronic hepatitis C genotype-1 infection given as monotherapy and in combination with peginterferon α 2a (P) and ribavirin (R). Hepatology 48 (Suppl. 1), 1849A (2008).
-
(2008)
Hepatology
, vol.48
, Issue.SUPPL. 1
-
-
Manns, M.P.1
Bourliere, M.2
Benhamou, Y.3
-
200
-
-
65749112245
-
In vitro activity and pre-clinical profile of TMC435350, a potent HCV protease inhibitor
-
Lin TI, Lenz O, Fanning G et al. In vitro activity and pre-clinical profile of TMC435350, a potent HCV protease inhibitor. Antimicrob. Agents Chemother. (2009).
-
(2009)
Antimicrob. Agents Chemother
-
-
Lin, T.I.1
Lenz, O.2
Fanning, G.3
-
201
-
-
42349088281
-
results of a Phase I placebo-controlled trial in healthy volunteers to examine the safety, tolerability and pharmacokinetics of the HCV protease inhibitor TMC435350 after single and repeated dosing
-
Verloes R, Farha KA, van Vliet A et al. results of a Phase I placebo-controlled trial in healthy volunteers to examine the safety, tolerability and pharmacokinetics of the HCV protease inhibitor TMC435350 after single and repeated dosing. Hepatology 46(Suppl. 1), 1318A (2007).
-
(2007)
Hepatology
, vol.46
, Issue.SUPPL. 1
-
-
Verloes, R.1
Farha, K.A.2
van Vliet, A.3
-
202
-
-
46249120293
-
Safety of the HCV protease inhibitor TMC435350 in healthy volunteers and safety and activity in chronic hepatitis C infected individuals: A Phase I study
-
S
-
Reesink H, Verloes R, Abou Farha K et al. Safety of the HCV protease inhibitor TMC435350 in healthy volunteers and safety and activity in chronic hepatitis C infected individuals: a Phase I study. J. Hepatol. 48 (Suppl. 2), S28 (2008).
-
(2008)
J. Hepatol
, vol.48
, Issue.SUPPL. 2
, pp. 28
-
-
Reesink, H.1
Verloes, R.2
Abou Farha, K.3
-
203
-
-
69549115967
-
-
Godofsky E, Afdhal N, Rustgi V et al. First clinical results for a novel antiviral treatment for hepatitis C: a Phase I/II dose escalation trial assessing, tolerance, pharmacokinetics, and antiviral activity of NM283. J. Hepatol. 40(Suppl. 1), S35 (2004).
-
Godofsky E, Afdhal N, Rustgi V et al. First clinical results for a novel antiviral treatment for hepatitis C: a Phase I/II dose escalation trial assessing, tolerance, pharmacokinetics, and antiviral activity of NM283. J. Hepatol. 40(Suppl. 1), S35 (2004).
-
-
-
-
204
-
-
69549089650
-
-
Afdhal N, O Brien C, Godofsky E et al. Valopicitabine (NM283), alone or with peginterferon, compared to peg interferon/ribavirin (pegifn/RBV) re-treatment in hepatitis patients with prior non-response to PEGIFN/RBV: week 24 results. J. Hepatol. 44(Suppl. 2), S19 (2006).
-
Afdhal N, O Brien C, Godofsky E et al. Valopicitabine (NM283), alone or with peginterferon, compared to peg interferon/ribavirin (pegifn/RBV) re-treatment in hepatitis patients with prior non-response to PEGIFN/RBV: week 24 results. J. Hepatol. 44(Suppl. 2), S19 (2006).
-
-
-
-
205
-
-
34548789741
-
Valopicitabine (NM283), alone or with peg-interferon, compared to peg interferon/ribavirin (PEGIFN/RBV) retreatment in patients with HCV-1 infection and prior non-response to PEGIFN/RBV: One-year results
-
S
-
Afdhal N, O'Brien C, Godofsky E et al. Valopicitabine (NM283), alone or with peg-interferon, compared to peg interferon/ribavirin (PEGIFN/RBV) retreatment in patients with HCV-1 infection and prior non-response to PEGIFN/RBV: one-year results. J. Hepatol. 46(Suppl. 1), S5 (2007).
-
(2007)
J. Hepatol
, vol.46
, Issue.SUPPL. 1
, pp. 5
-
-
Afdhal, N.1
O'Brien, C.2
Godofsky, E.3
-
206
-
-
33645232568
-
The novel nucleoside analog R1479 (4′-azidocytidine) is a potent inhibitor of NS5B-dependent RNA synthesis and hepatitis C virus replication in cell culture
-
Klumpp K, Leveque V, Le Pogam S et al. The novel nucleoside analog R1479 (4′-azidocytidine) is a potent inhibitor of NS5B-dependent RNA synthesis and hepatitis C virus replication in cell culture. J. Biol. Chem. 281(7), 3793-3799 (2006).
-
(2006)
J. Biol. Chem
, vol.281
, Issue.7
, pp. 3793-3799
-
-
Klumpp, K.1
Leveque, V.2
Le Pogam, S.3
-
207
-
-
49649094687
-
Robust antiviral activity of R1626, a novel nucleoside analog: A randomized, placebo-controlled study in patients with chronic hepatitis C
-
Roberts SK, Cooksley G, Dore GJ et al. Robust antiviral activity of R1626, a novel nucleoside analog: a randomized, placebo-controlled study in patients with chronic hepatitis C. Hepatology 48(2), 398-406 (2008).
-
(2008)
Hepatology
, vol.48
, Issue.2
, pp. 398-406
-
-
Roberts, S.K.1
Cooksley, G.2
Dore, G.J.3
-
208
-
-
49649125855
-
R1626 plus peginterferon α-2a provides potent suppression of hepatitis C virus RNA and significant antiviral synergy in combination with ribavirin
-
Pockros PJ, Nelson D, Godofsky E et al. R1626 plus peginterferon α-2a provides potent suppression of hepatitis C virus RNA and significant antiviral synergy in combination with ribavirin. Hepatology 48(2), 385-397 (2008).
-
(2008)
Hepatology
, vol.48
, Issue.2
, pp. 385-397
-
-
Pockros, P.J.1
Nelson, D.2
Godofsky, E.3
-
209
-
-
34548285968
-
Antiviral activity of the non-nucleoside polymerase inhibitor, HCV-796, in combination with pegylated interferon α-2b in treatment-naive patients with chronic HCV
-
S
-
Villano SA, Raible D, Harper D et al. Antiviral activity of the non-nucleoside polymerase inhibitor, HCV-796, in combination with pegylated interferon α-2b in treatment-naive patients with chronic HCV. J. Hepatol. 46(Suppl. 1), S24 (2007).
-
(2007)
J. Hepatol
, vol.46
, Issue.SUPPL. 1
, pp. 24
-
-
Villano, S.A.1
Raible, D.2
Harper, D.3
-
210
-
-
41749085866
-
Antiviral, pharmacokinetic and safety data for GS-9190, a non-nucleoside HCV NS5B polymerase inhibitor, in a phase-1 trial in HCV genotype 1 infected subjects
-
Bavisotto L, Wang CC, Jacobsen IM et al. Antiviral, pharmacokinetic and safety data for GS-9190, a non-nucleoside HCV NS5B polymerase inhibitor, in a phase-1 trial in HCV genotype 1 infected subjects. Hepatology 46(4), 49A (2007).
-
(2007)
Hepatology
, vol.46
, Issue.4
-
-
Bavisotto, L.1
Wang, C.C.2
Jacobsen, I.M.3
-
211
-
-
35748960801
-
Safety, pharmacokinetics and antiviral effect of BILB1941, a novel HCV RNA polymerase inhibitor, after 5 days oral treatment in patients with chronic hepatitis C
-
S
-
Erhardt A, Wedemeyer H, Benhamou Y et al. Safety, pharmacokinetics and antiviral effect of BILB1941, a novel HCV RNA polymerase inhibitor, after 5 days oral treatment in patients with chronic hepatitis C. J. Hepatol. 46(Suppl. 1), S222 (2007).
-
(2007)
J. Hepatol
, vol.46
, Issue.SUPPL. 1
, pp. 222
-
-
Erhardt, A.1
Wedemeyer, H.2
Benhamou, Y.3
-
212
-
-
64349088294
-
-
Li H, Tatlock J, Linton A et al. Discovery of (R)-6-cyclopentyl-6-(2-(2,6-diethylpyridin-4-yl)ethyl)-3- ((5,7-dimethyl-[1,2,4] triazolo[1,5-a]pyrimidin-2-yl)methyl)- 4-hydroxy-5,6-dihydropyran-2-on e (PF-00868554) as a potent and orally available hepatitis C virus polymerase inhibitor. J. Med. Chem. (2009) (In Press).
-
Li H, Tatlock J, Linton A et al. Discovery of (R)-6-cyclopentyl-6-(2-(2,6-diethylpyridin-4-yl)ethyl)-3- ((5,7-dimethyl-[1,2,4] triazolo[1,5-a]pyrimidin-2-yl)methyl)- 4-hydroxy-5,6-dihydropyran-2-on e (PF-00868554) as a potent and orally available hepatitis C virus polymerase inhibitor. J. Med. Chem. (2009) (In Press).
-
-
-
-
213
-
-
67049085259
-
Antiviral activity of the HCV polymerase inhibitor PF-00868554 administered as monotherapy in HCV genotype 1 infected subjects
-
Hammond J, Rosario MC, Wagner F et al. Antiviral activity of the HCV polymerase inhibitor PF-00868554 administered as monotherapy in HCV genotype 1 infected subjects. Hepatology 48(Suppl. 1), LB11 (2008).
-
(2008)
Hepatology
, vol.48
, Issue.SUPPL. 1
-
-
Hammond, J.1
Rosario, M.C.2
Wagner, F.3
-
214
-
-
84863052853
-
Results of a Phase I safety, tolerability and pharmacokinetic study of ANA598, a nonnucleoside NS5B polymerase inhibitor, in healthy volunteers
-
Rahimy MH, Crowley CA, Freddo L, Sergeeva MV, Golec B. Results of a Phase I safety, tolerability and pharmacokinetic study of ANA598, a nonnucleoside NS5B polymerase inhibitor, in healthy volunteers. Hepatology 48(Suppl. 1), LB13 (2008).
-
(2008)
Hepatology
, vol.48
, Issue.SUPPL. 1
-
-
Rahimy, M.H.1
Crowley, C.A.2
Freddo, L.3
Sergeeva, M.V.4
Golec, B.5
-
215
-
-
72049113415
-
BMS-790052 is a First-in-class potent hepatitis C virus (HCV) NS5A inhibitor for patients with chronic HCV infection: Results from a proof-of-concept study
-
Nettles R, Chien C, Chun E et al. BMS-790052 is a First-in-class potent hepatitis C virus (HCV) NS5A inhibitor for patients with chronic HCV infection: results from a proof-of-concept study. Hepatology 48(Suppl. 1), LB12 (2008).
-
(2008)
Hepatology
, vol.48
, Issue.SUPPL. 1
-
-
Nettles, R.1
Chien, C.2
Chun, E.3
-
216
-
-
34547625235
-
Proof of concept study of celgosivir in combination with peginterferon α-2b and ribavirin in chronic hepatitis c genotype-1 non-responder patients
-
Kaita K, Yoshida E, Kunimoto D et al. Proof of concept study of celgosivir in combination with peginterferon α-2b and ribavirin in chronic hepatitis c genotype-1 non-responder patients. J. Hepatol. 46(Suppl. 1), S56-S57 (2007).
-
(2007)
J. Hepatol
, vol.46
, Issue.SUPPL. 1
-
-
Kaita, K.1
Yoshida, E.2
Kunimoto, D.3
-
217
-
-
0021159379
-
Cyclophilin: A specific cytosolic binding protein for cyclosporin A
-
Handschumacher RE, Harding MW, Rice J, Drugge RJ, Speicher DW. Cyclophilin: a specific cytosolic binding protein for cyclosporin A. Science 226(4674), 544-547 (1984).
-
(1984)
Science
, vol.226
, Issue.4674
, pp. 544-547
-
-
Handschumacher, R.E.1
Harding, M.W.2
Rice, J.3
Drugge, R.J.4
Speicher, D.W.5
-
218
-
-
0025893168
-
Calcineurin is a common target of cyclophilin - cyclosporin A and FKBP-FK506 complexes
-
Liu J, Farmer JD Jr, Lane WS, Friedman J, Weissman I, Schreiber SL. Calcineurin is a common target of cyclophilin - cyclosporin A and FKBP-FK506 complexes. Cell 66(4), 807-815 (1991).
-
(1991)
Cell
, vol.66
, Issue.4
, pp. 807-815
-
-
Liu, J.1
Farmer Jr, J.D.2
Lane, W.S.3
Friedman, J.4
Weissman, I.5
Schreiber, S.L.6
-
219
-
-
24144468662
-
Suppression of hepatitis C virus replication by cyclosporin a is mediated by blockade of cyclophilins
-
Nakagawa M, Sakamoto N, Tanabe Y et al. Suppression of hepatitis C virus replication by cyclosporin a is mediated by blockade of cyclophilins. Gastroenterology 129(3), 1031-1041 (2005).
-
(2005)
Gastroenterology
, vol.129
, Issue.3
, pp. 1031-1041
-
-
Nakagawa, M.1
Sakamoto, N.2
Tanabe, Y.3
-
220
-
-
21244433445
-
Cyclophilin B is a functional regulator of hepatitis C virus RNA polymerase
-
Watashi K, Ishii N, Hijikata M et al. Cyclophilin B is a functional regulator of hepatitis C virus RNA polymerase. Mol. Cell 19(1), 111-122 (2005).
-
(2005)
Mol. Cell
, vol.19
, Issue.1
, pp. 111-122
-
-
Watashi, K.1
Ishii, N.2
Hijikata, M.3
-
221
-
-
34249817897
-
Characterization of hepatitis C virus subgenomic replicon resistance to cyclosporine in vitro
-
Robida JM, Nelson HB, Liu Z, Tang H. Characterization of hepatitis C virus subgenomic replicon resistance to cyclosporine in vitro. J. Virol. 81(11), 5829-5840 (2007).
-
(2007)
J. Virol
, vol.81
, Issue.11
, pp. 5829-5840
-
-
Robida, J.M.1
Nelson, H.B.2
Liu, Z.3
Tang, H.4
-
222
-
-
33646015668
-
The non-immunosuppressive cyclosporin DEBIO-025 is a potent inhibitor of hepatitis C virus replication in vitro
-
Paeshuyse J, Kaul A, De Clercq E et al. The non-immunosuppressive cyclosporin DEBIO-025 is a potent inhibitor of hepatitis C virus replication in vitro. Hepatology 43(4), 761-770 (2006).
-
(2006)
Hepatology
, vol.43
, Issue.4
, pp. 761-770
-
-
Paeshuyse, J.1
Kaul, A.2
De Clercq, E.3
-
223
-
-
33646194456
-
Diverse effects of cyclosporine on hepatitis C virus strain replication
-
Ishii N, Watashi K, Hishiki T et al. Diverse effects of cyclosporine on hepatitis C virus strain replication. J. Virol. 80(9), 4510-4520 (2006).
-
(2006)
J. Virol
, vol.80
, Issue.9
, pp. 4510-4520
-
-
Ishii, N.1
Watashi, K.2
Hishiki, T.3
-
224
-
-
22544457641
-
Cyclophilin B escorts the hepatitis C virus RNA polymerase: A viral achilles heel?
-
Heitman J, Cullen BR. Cyclophilin B escorts the hepatitis C virus RNA polymerase: a viral achilles heel? Mol. Cell 19(2), 145-146 (2005).
-
(2005)
Mol. Cell
, vol.19
, Issue.2
, pp. 145-146
-
-
Heitman, J.1
Cullen, B.R.2
-
225
-
-
33645911783
-
Evaluation of the anti-hepatitis C virus effects of cyclophilin inhibitors, cyclosporin A, and NIM811
-
Goto K, Watashi K, Murata T, Hishiki T, Hijikata M, Shimotohno K. Evaluation of the anti-hepatitis C virus effects of cyclophilin inhibitors, cyclosporin A, and NIM811. Biochem. Biophys. Res. Commun. 343(3), 879-884 (2006).
-
(2006)
Biochem. Biophys. Res. Commun
, vol.343
, Issue.3
, pp. 879-884
-
-
Goto, K.1
Watashi, K.2
Murata, T.3
Hishiki, T.4
Hijikata, M.5
Shimotohno, K.6
-
226
-
-
34447514070
-
Chemical genetics approach to hepatitis C virus replication: Cyclophilin as a target for anti-hepatitis C virus strategy
-
Watashi K, Shimotohno K. Chemical genetics approach to hepatitis C virus replication: cyclophilin as a target for anti-hepatitis C virus strategy. Rev. Med. Virol. 17(4), 245-252 (2007).
-
(2007)
Rev. Med. Virol
, vol.17
, Issue.4
, pp. 245-252
-
-
Watashi, K.1
Shimotohno, K.2
-
227
-
-
34247383488
-
Evaluation of a cyclophilin inhibitor in hepatitis C virus-infected chimeric mice in vivo
-
Inoue K, Umehara T, Ruegg UT et al. Evaluation of a cyclophilin inhibitor in hepatitis C virus-infected chimeric mice in vivo. Hepatology 45(4), 921-928 (2007).
-
(2007)
Hepatology
, vol.45
, Issue.4
, pp. 921-928
-
-
Inoue, K.1
Umehara, T.2
Ruegg, U.T.3
-
228
-
-
40949117600
-
The cyclophilin inhibitor Debio-025 shows potent anti-hepatitis C effect in patients coinfected with hepatitis C and human immunodeficiency virus
-
Flisiak R, Horban A, Gallay P et al. The cyclophilin inhibitor Debio-025 shows potent anti-hepatitis C effect in patients coinfected with hepatitis C and human immunodeficiency virus. Hepatology 47(3), 817-826 (2008).
-
(2008)
Hepatology
, vol.47
, Issue.3
, pp. 817-826
-
-
Flisiak, R.1
Horban, A.2
Gallay, P.3
-
229
-
-
36249000683
-
Viral kinetics during 14-day treatment with DEBIO-025 demonstrate efficient blocking of viral replication in different HCV genotypes without signs of emerging viral resistance
-
S
-
Herrmann E, Flisiak R, Horban A et al. Viral kinetics during 14-day treatment with DEBIO-025 demonstrate efficient blocking of viral replication in different HCV genotypes without signs of emerging viral resistance. J. Hepatol. 46(Suppl. 1), S40 (2007).
-
(2007)
J. Hepatol
, vol.46
, Issue.SUPPL. 1
, pp. 40
-
-
Herrmann, E.1
Flisiak, R.2
Horban, A.3
|