Disparate roles for TNF-α and fas ligand in concanavalin A-induced hepatitis

Journal of Immunology

Volumn 160, Issue 8, 1998, Pages 4082-4089

  Ksontini, Riadh ^a   Colagiovanni, Dorothy B ^b   Josephs, Michael D ^a   Edwards III, Carl K ^b   Tannahill, Cynthia L ^a   Solorzano, Carmen C ^a   Norman, James ^c   Denham, Woody ^c   Clare Salzler, Michael ^a   MacKay, Sally L D ^a   Moldawer, Lyle L ^a  

^a UNIVERSITY OF FLORIDA COLLEGE OF MEDICINE   (United States)

^b AMGEN INC   (United States)

^c UNIVERSITY OF SOUTH FLORIDA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ASPARTATE AMINOTRANSFERASE; CONCANAVALIN A; DNA FRAGMENT; FAS ANTIGEN; INTERLEUKIN 1BETA CONVERTING ENZYME; MATRIX METALLOPROTEINASE INHIBITOR; MESSENGER RNA; PROTEIN; PROTEINASE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CONTROLLED STUDY; HEPATITIS; IMMUNOBLOTTING; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

ANIMALS; APOPTOSIS; BASE SEQUENCE; CASPASE 1; CONCANAVALIN A; CYSTEINE ENDOPEPTIDASES; DNA PRIMERS; FAS LIGAND PROTEIN; HEPATITIS, TOXIC; LIVER; MALE; MEMBRANE GLYCOPROTEINS; MICE; MICE, INBRED C57BL; POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR NECROSIS FACTOR-ALPHA; UP-REGULATION;

EID: 0032522802     PISSN: 00221767     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (43)

1. van der Poll, T., and S. F. Lowry. 1995. Tumor necrosis factor in sepsis: mediator of multiple organ failure or essential part of host defense? Shock 3:1.
2. Fraser, A., and G. Evan. 1996. A license to kill. Cell 85:781.
3. Nagata, S. 1997. Apoptosis by death factor. Cell 88:355.
4. Nagata, S. 1996. Apoptosis mediated by the Fas system. Prog. Mol. Subcell. Biol. 16:87.
5. Vignaux, F., and P. Golstein. 1994. Fas-based lymphocyte-mediated cytotoxicity against syngeneic activated lymphocytes: a regulatory pathway? Eur. J. Immunol. 24:923.
6. Griffith, T. S., T. Brunner, S. M. Fletcher, D. R. Green, and T. A. Ferguson. 1995. Fas ligand-induced apoptosis as a mechanism of immune privilege. Science 270:1189.
7. Yuan, J., S. Shaham, S. Ledoux, H. M. Ellis, and H. R. Horvitz. 1993. The C. elegans cell death gene ced-3 encodes a protein similar to mammalian interleukin-1 beta-converting enzyme. Cell 75:641.
8. Alnemri, E. S., D. J. Livingston, D. W. Nicholson, G. Salvesen, N. A. Thornberry, W. W. Wong, and J. Yuan. 1996. Human ICE/CED-3 protease nomenclature. Cell 87:171.
9. Kuida, K., J. A. Lippke, G. Ku, M. W. Harding, D. J. Livingston, M. S. Su, and R. A. Flavell. 1995. Altered cytokine export and apoptosis in mice deficient in interleukin-1 beta converting enzyme. Science 267:2000.
10. Enari, M., H. Hug, and S. Nagata. 1995. Involvement of an ICE-like protease in Fas-mediated apoptosis. Nature 375:78.
11. Los, M., M. Van de Craen, L. C. Penning, H. Schenk, M. Westendorp, P. A. Baeuerle, W. Droge, P. H. Krammer, W. Fiers, and K. Schulze Osthoff. 1995. Requirement of an ICE/CED-3 protease for Fas/APO-1-mediated apoptosis. Nature 375:81.
12. Martin, S. J., and D. R. Green. 1995. Protease activation during apoptosis: death by a thousand cuts? Cell 82:349.
13. Miller, D. K., J. Myerson, and J. W. Becker. 1997. The interleukin-1 beta converting enzyme family of cysteine proteases. J. Cell Biochem. 64:2.
14. Ghayur, T., S. Banerjee, M. Hugunin, D. Butler, L. Herzog, A. Carter, L. Quintal, L. Sekut, R. Talanian, M. Paskind, W. Wong, R. Kamen, D. Tracey, and H. Allen. 1997. Caspase-1 processes IFN-gamma-inducing factor and regulates LPS-induced IFN-gamma production. Nature 386:619.
15. Tiegs, G., J. Hentschel, and A. Wendel. 1992. A T cell-dependent experimental liver injury in mice inducible by concanavalin A. J. Clin. Invest. 90:196.
16. Knolle, P. A., G. Gerken, E. Loser, H. P. Dienes, F. Gantner, G. Tiegs, K. H. Meyer zum Buschenfelde, and A. W. Lohse. 1996. Role of sinusoidal endothelial cells of the liver in concanavalin A-induced hepatic injury in mice. Hepatology 24:824.
17. Kusters, S., F. Gantner, G. Kunstle, and G. Tiegs. 1996. Interferon gamma plays a critical role in T cell-dependent liver injury in mice initiated by concanavalin A. Gastroenterology 111:462.
18. Mizuhara, H., E. O'Neill, N. Seki, T. Ogawa, C. Kusunoki, K. Otsuka, S. Satoh, M. Niwa, H. Senoh, and H. Fujiwara. 1994. T cell activation-associated hepatic injury: mediation by tumor necrosis factors and protection by interleukin 6. J. Exp. Med. 179:1529.
19. Solorzano, C. C., R. Ksontini, J. H. Pruitt, P. J. Hess, P. D. Edwards, A. Kaibara, A. Abouhamze, T. Auffenberg, R. E. Galardy, J. N. Vauthey, E. M. Copeland, C. K. Edwards, G. Y. Lauwers, M. Clare-Salzler, S. L. MacKay, L. L. Moldawer, and D. D. Lazarus. 1997. Involvement of 26-kDa cell-associated TNF-α in experimental hepatitis and exacerbation of liver injury with a matrix metalloproteinase inhibitor. J. Immunol. 158:414.
20. Solorzano, C. C., R. Ksontini, J. H. Pruitt, T. Auffenberg, C. Tannahill, R. E. Galardy, G. P. Schultz, S. L. MacKay, E. M. Copeland, and L. L. Moldawer. 1997. A matrix metalloproteinase inhibitor prevents processing of tumor necrosis factor alpha (TNF alpha) and abrogates endotoxin-induced lethality. Shock 7:427.
21. Kondo, T., T. Suda, H. Fukuyama, M. Adachi, and S. Nagata. 1997. Essential roles of the Fas ligand in the development of hepatitis. Nat. Med. 3:409.
22. Gantner, F., M. Leist, A. W. Lohse, P. G. Germann, and G. Tiegs. 1995. Concanavalin A-induced T-cell-mediated hepatic injury in mice: the role of tumor necrosis factor. Hepatology 21:190.
23. Tanaka, M., T. Suda, K. Haze, N. Nakamura, K. Sato, F. Kimura, K. Motoyoshi, M. Mizuki, S. Tagawa, S. Ohga, K. Hatake, A. H. Drummond, and S. Nagata. 1996. Fas ligand in human serum. Nat. Med. 2:317.
24. Kayagaki, N., A. Kawasaki, T. Ebata, H. Ohmoto, S. Ikeda, S. Inoue, K. Yoshino, K. Okumura, and H. Yagita. 1995. Metalloproteinase-mediated release of human Fas ligand. J. Exp. Med. 182:1777.
25. Grobelny, D., L. Poncz, and R. E. Galardy. 1992. Inhibition of human skin fibroblast collagenase, thermolysin, and Pseudomonas aeruginosa elastase by peptide hydroxamic acids. Biochemistry 31:7152.
26. Gijbels, K., R. E. Galardy, and L. Steinman. 1994. Reversal of experimental autoimmune encephalomyelitis with a hydroxamate inhibitor of matrix metalloproteases. J. Clin. Invest. 94:2177.
27. Espat, N. J., J. C. Cendan, E. A. Beierle, T. A. Auffenberg, J. Rosenberg, D. Russell, J. S. Kenney, E. Fischer, W. Montegut, and S. F. Lowry. 1995. PEG-BP-30 monotherapy attenuates the cytokine-mediated inflammatory cascade in baboon Escherichia coli septic shock. J. Surg. Res. 59:153.
28. Zhou, T., C. K. Edwards, R. J. Evans, H. Bluethmann, and J. D. Mountz. 1997. Fas and tumor necrosis factor receptor I mediated activation induced cell death of macrophages. J. Immunol. In press.
29. Mountz, J. D., T. Zhou, X. Su, J. Cheng, M. Pierson, H. Bluethmann, and G. K. Edwards. 1996. Autoimmune disease results from multiple interactive defects in apoptosis induction molecules and signaling pathways. Behring Inst. Mitt. 200.
30. Chomczynski, P., and N. Sacchi. 1987. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162:156.
31. Van Zee, K. J., T. Kohno, E. Fischer, C. S. Rock, L. L. Moldawer, and S. F. Lowry. 1992. Tumor necrosis factor soluble receptors circulate during experimental and clinical inflammation and can protect against excessive tumor necrosis factor alpha in vitro and in vivo. Proc. Natl. Acad. Sci. USA 89:4845.
32. Ogasawara, J., R. Watanabe-Fukunaga, M. Adachi, A. Matsuzawa, T. Kasugai, Y. Kitamura, N. Itoh, T. Suda, and S. Nagata. 1993. Lethal effect of the anti-Fas antibody in mice. Nature 364:806.
33. Black, R. A., C. T. Rauch, C. J. Kozlosky, J. J. Peschon, J. L. Slack, M. F. Wolfson, B. J. Castner, K. L. Stocking, P. Reddy, S. Srinivasan, N. Nelson, N. Boiani, K. A. Schooley, M. Gerhart, R. Davis, J. N. Fitzner, R. S. Johnson, R. J. Paxton, C. J. March, and D. P. Cerretti. 1997. A metalloproteinase disintegrin that releases tumour-necrosis factor-alpha from cells. Nature 385:729.
34. Moss, M. L., S. L. Jin, M. E. Milla, W. Burkhart, H. L. Carter, W. J. Chen, W. C. Clay, J. R. Didsbury, D. Hassler, C. R. Hoffman, T. A. Kost, M. H. Lambert, M. A. Leesnitzer, P. McCauley, G. McGeehan, J. Mitchell, M. Moyer, G. Pahel, W. Rocque, L. K. Overton, F. Schoenen, T. Seaton, J. L. Su, J. Warner, and J. D. Becherer. 1997. Cloning of a disintegrin metalloproteinase that processes precursor tumour-necrosis factor-alpha. Nature 385:733.
35. Takahashi, T., M. Tanaka, C. I. Brannan, N. A. Jenkins, N. G. Copeland, T. Suda, and S. Nagata. 1994. Generalized lymphoproliferative disease in mice, caused by a point mutation in the Fas ligand. Cell 76:969.
36. Suda, T., T. Okazaki, Y. Naito, T. Yokota, N. Arai, S. Ozaki, K. Nakao, and S. Nagata. 1995. Expression of the Fas ligand in cells of T cell lineage. J. Immunol. 154:3806.
37. Liles, W. C., P. A. Kiener, J. A. Ledbetter, A. Aruffo, and S. J. Klebanoff. 1996. Differential expression of Fas (CD95) and Fas ligand on normal human phagocytes: implications for the regulation of apoptosis in neutrophils. J. Exp. Med. 184:429.
38. Cleveland, J. L., and J. N. Ihle. 1995. Contenders in FasL/TNF death signaling. Cell 81:479.
39. Galle, P. R., W. J. Hofmann, H. Walczak, H. Schaller, G. Otto, W. Stremmel, P. H. Krammer, and L. Runkel. 1995. Involvement of the CD95 (APO-1/Fas) receptor and ligand in liver damage. J. Exp. Med. 182:1223.
40. Watanabe, Y., M. Morita, and T. Akaike. 1996. Concanavalin A induces perforinmediated but not Fas-mediated hepatic injury. Hepatology 24:702.
41. Leist, M., F. Gantner, G. Kunstle, I. Bohlinger, G. Tiegs, H. Bluethmann, and A. Wendel. 1996. The 55-kD tumor necrosis factor receptor and CD95 independently signal murine hepatocyte apoptosis and subsequent liver failure. Mol. Med. 2:109.
42. Rodriguez, I., K. Matsuura, C. Ody, S. Nagata, and P. Vassalli. 1996. Systemic injection of a tripeptide inhibits the intracellular activation of CPP32-like proteases in vivo and fully protects mice against Fas-mediated fulminant liver destruction and death. J. Exp. Med. 184:2067.
43. -1- mice. J. Immunol. 159:1418.