ROC1/RBX1 E3 ubiquitin ligase silencing suppresses tumor cell growth via sequential induction of G2-M arrest, apoptosis, and senescence

Cancer Research

Volumn 69, Issue 12, 2009, Pages 4974-4982

  Jia, Lijun ^a   Soengas, Maria S ^b   Sun, Yi ^a,c  

^a UNIVERSITY OF MICHIGAN COMPREHENSIVE CANCER CENTER   (United States)

^b Centro Nacional de Investigaciones Oncológicas   (Spain)

^c UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN B1; CYCLIN DEPENDENT KINASE 1; PROTEIN BCL 2; PROTEIN MCL 1; PROTEIN P16; PROTEIN P21; PROTEIN P53; PUMA PROTEIN; REGULATOR OF CULLINS 1; RING FINGER PROTEIN; SMALL INTERFERING RNA; STRATIFIN; SURVIVIN; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CANCER CELL CULTURE; CANCER INHIBITION; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CONTROLLED STUDY; DNA DAMAGE; GENE SILENCING; HUMAN; HUMAN CELL; HUMAN TISSUE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENESCENCE; TUMOR GROWTH;

APOPTOSIS; BASE SEQUENCE; CARRIER PROTEINS; CELL AGING; CELL DIVISION; CELL LINE, TUMOR; DNA PRIMERS; FLOW CYTOMETRY; FLUORESCENT ANTIBODY TECHNIQUE; G2 PHASE; GENE SILENCING; HUMANS; NEOPLASMS;

EID: 67449143478     PISSN: 00085472     EISSN: 15387445     Source Type: Journal    
DOI: 10.1158/0008-5472.CAN-08-4671     Document Type: Article

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