Focal cerebral ischemia in rats alters APP processing and expression of Aβ peptide degrading enzymes in the thalamus

Neurobiology of Disease

Volumn 35, Issue 1, 2009, Pages 103-113

  Hiltunen, Mikko ^a   Mäkinen, Petra ^a   Peräniemi, Sirpa ^b   Sivenius, Juhani ^a,c   van Groen, Thomas ^d,e   Soininen, Hilkka ^a   Jolkkonen, Jukka ^a  

^a KUOPIO UNIVERSITY HOSPITAL   (Finland)

^b UNIVERSITY OF EASTERN FINLAND   (Finland)

^c Brain Research and Rehabilitation Center Neuron   (Finland)

^d UNIVERSITY OF ALABAMA AT BIRMINGHAM   (United States)

^e University of Alabama at Birmingham   (United States)

Author keywords

secretase; A peptide; Alzheimer's disease; Calcium; Golgi localized ear containing ARF binding protein; Insulin degrading enzyme; Ischemia; Neprilysin; Thalamus

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; BETA SECRETASE; CALCIUM; INSULINASE; MEMBRANE METALLOENDOPEPTIDASE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN INFARCTION; BRAIN ISCHEMIA; CONTROLLED STUDY; ENZYME ACTIVITY; MALE; MIDDLE CEREBRAL ARTERY OCCLUSION; MOLECULAR DYNAMICS; NONHUMAN; PATHOGENICITY; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROCESSING; RAT; THALAMUS;

ADAPTOR PROTEINS, VESICULAR TRANSPORT; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; AMYLOID PRECURSOR PROTEIN SECRETASES; ANIMALS; ASPARTIC ENDOPEPTIDASES; BRAIN INFARCTION; CALCIUM; CASPASE 3; DISEASE MODELS, ANIMAL; FUNCTIONAL LATERALITY; GENE EXPRESSION REGULATION; INFARCTION, MIDDLE CEREBRAL ARTERY; INSULYSIN; MALE; NEPRILYSIN; PROTEIN STRUCTURE, TERTIARY; RATS; RATS, WISTAR; THALAMUS; TIME FACTORS;

EID: 67349143960     PISSN: 09699961     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.nbd.2009.04.009     Document Type: Article

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