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Volumn 22, Issue 3, 1997, Pages 567-572

Paraquat-induced formation of leukotriene B4 in rat lungs: Modulation by N-acetylcysteine

Author keywords

Alveolar macrophages; Arachidonic acid; Bronchoalveolar lavage; Epithelial type II cells; Free radicals; Leukotriene LTB4; N Acetylcysteine; Paraquat

Indexed keywords

ACETYLCYSTEINE; ANTIOXIDANT; ARACHIDONATE 5 LIPOXYGENASE; ARACHIDONIC ACID; FREE RADICAL; LEUKOTRIENE B4; PARAQUAT; SCAVENGER;

EID: 0031027060     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0891-5849(96)00385-1     Document Type: Article
Times cited : (17)

References (30)
  • 1
    • 0016230379 scopus 로고
    • Studies on the mechanism of the lung toxicity of paraquat: Comparison of tissue distribution and some biochemical parameters in rats and rabbits
    • Ilett K. F., Stripp B., Menard R. H., Reid W. D., Gilette J. R. Studies on the mechanism of the lung toxicity of paraquat: Comparison of tissue distribution and some biochemical parameters in rats and rabbits. Toxicol. Appl. Pharmacol. 28:1974;216-226.
    • (1974) Toxicol. Appl. Pharmacol. , vol.28 , pp. 216-226
    • Ilett, K.F.1    Stripp, B.2    Menard, R.H.3    Reid, W.D.4    Gilette, J.R.5
  • 2
    • 0019194294 scopus 로고
    • Tissue and cellular disposition of paraquat in mice
    • Waddell W. J., Marlowe C. Tissue and cellular disposition of paraquat in mice. Toxicol. Appl. Pharmacol. 56:1980;127-140.
    • (1980) Toxicol. Appl. Pharmacol. , vol.56 , pp. 127-140
    • Waddell, W.J.1    Marlowe, C.2
  • 3
    • 0023905539 scopus 로고
    • The accumulation and localisation of putrescine, spermidine, spermine and paraquat in the rat lung
    • Wyatt I., Soames A. R., Clay M. F., Smith L. L. The accumulation and localisation of putrescine, spermidine, spermine and paraquat in the rat lung. Biochem. Pharmacol. 37:1988;1909-1918.
    • (1988) Biochem. Pharmacol. , vol.37 , pp. 1909-1918
    • Wyatt, I.1    Soames, A.R.2    Clay, M.F.3    Smith, L.L.4
  • 4
    • 0015821035 scopus 로고
    • Bipyridilium quaternary salts and related compounds; Pulse radiolysis studies and the reaction of paraquat radicals with oxygen, implications for the mode of action of bipyridilium herbicides
    • Farrington J. A., Ebert M., Land E. Y., Fletcher K. Bipyridilium quaternary salts and related compounds; Pulse radiolysis studies and the reaction of paraquat radicals with oxygen, implications for the mode of action of bipyridilium herbicides. Biochem. Biophys. Acta. 314:1973;372-381.
    • (1973) Biochem. Biophys. Acta , vol.314 , pp. 372-381
    • Farrington, J.A.1    Ebert, M.2    Land, E.Y.3    Fletcher, K.4
  • 7
    • 0021288729 scopus 로고
    • 4 production by human alveolar macrophages: A potential mechanism for amplifying inflammation in the lung
    • 4 production by human alveolar macrophages: A potential mechanism for amplifying inflammation in the lung. Am. Rev. Resp. Dis. 29:1984;106-111.
    • (1984) Am. Rev. Resp. Dis. , vol.29 , pp. 106-111
    • Martin, T.R.1    Altman, L.C.2    Albert, R.C.3    Henderson, W.R.4
  • 10
    • 0021280477 scopus 로고
    • The effectiveness of N-acetylcysteine in isolated hepatocytes, against the toxicity of paracetamol, acrolein, and paraquat
    • Dawson J. R., Norbeck K., Anundi I., Moldeus P. The effectiveness of N-acetylcysteine in isolated hepatocytes, against the toxicity of paracetamol, acrolein, and paraquat. Arch. Toxicol. 55:1984;11.
    • (1984) Arch. Toxicol. , vol.55 , pp. 11
    • Dawson, J.R.1    Norbeck, K.2    Anundi, I.3    Moldeus, P.4
  • 11
    • 0022182825 scopus 로고
    • Lung cell oxidant injury: Decrease in oxidant mediated cytotoxicity by N-acetylcysteine
    • Simon L. M., Suttorp N. Lung cell oxidant injury: Decrease in oxidant mediated cytotoxicity by N-acetylcysteine. Eur. J. Respir. Dis. 66:(Suppl.):1985;132-135.
    • (1985) Eur. J. Respir. Dis. , vol.66 , Issue.SUPPL. , pp. 132-135
    • Simon, L.M.1    Suttorp, N.2
  • 12
    • 0021996122 scopus 로고
    • Oxidant lung injury: Intervention with sulfhydril reagents
    • Patterson C. E., Butler J. A., Byrne F. D., Rhodes M. I. Oxidant lung injury: Intervention with sulfhydril reagents. Lung. 163:1985;3-32.
    • (1985) Lung , vol.163 , pp. 3-32
    • Patterson, C.E.1    Butler, J.A.2    Byrne, F.D.3    Rhodes, M.I.4
  • 15
    • 0022527271 scopus 로고
    • An improved method for isolating type II cells in high yield and purity
    • Dobbs L. G., Gonzalez R., Williams M. C. An improved method for isolating type II cells in high yield and purity. Am. Rev. Resp. Dis. 134:1986;141-145.
    • (1986) Am. Rev. Resp. Dis. , vol.134 , pp. 141-145
    • Dobbs, L.G.1    Gonzalez, R.2    Williams, M.C.3
  • 16
    • 0023631208 scopus 로고
    • Inhibition by methylprednisolone of zymosan-induced leukotriene synthesis in alveolar macrophages
    • Peters-Golden M., Thebert P. Inhibition by methylprednisolone of zymosan-induced leukotriene synthesis in alveolar macrophages. Am. Rev. Respir. Dis. 130:1987;1020-1026.
    • (1987) Am. Rev. Respir. Dis. , vol.130 , pp. 1020-1026
    • Peters-Golden, M.1    Thebert, P.2
  • 17
    • 0023948376 scopus 로고
    • Inhibitory effect of exogenous arachidonic acid on alveolar macrophage 5-lipoxygenase metabolism
    • Peters-Golden M., Shelly C. Inhibitory effect of exogenous arachidonic acid on alveolar macrophage 5-lipoxygenase metabolism. J. Immunol. 140:1988;958-1966.
    • (1988) J. Immunol. , vol.140 , pp. 958-1966
    • Peters-Golden, M.1    Shelly, C.2
  • 22
    • 0020034381 scopus 로고
    • Differential paraquat uptake and redox kinetics of rat granular pneumocytes and alveolar macrophages
    • Forman H. J., Aldrich T. K., Posner M. A., Fisher A. B. Differential paraquat uptake and redox kinetics of rat granular pneumocytes and alveolar macrophages. J. Pharmacol. Exp. Ther. 221:1982;428-433.
    • (1982) J. Pharmacol. Exp. Ther. , vol.221 , pp. 428-433
    • Forman, H.J.1    Aldrich, T.K.2    Posner, M.A.3    Fisher, A.B.4
  • 24
    • 0023867657 scopus 로고
    • Arachidonic acid metabolism by rat alveolar epithelial cells
    • Chauncey J. B., Peters-Golden M., Simon R. Arachidonic acid metabolism by rat alveolar epithelial cells. Lab. Invest. 58:1988;133-140.
    • (1988) Lab. Invest. , vol.58 , pp. 133-140
    • Chauncey, J.B.1    Peters-Golden, M.2    Simon, R.3
  • 25
    • 0026059488 scopus 로고
    • Arachidonic acid metabolism. Implications of biological chemistry for lung function and diseases
    • Holtzman M. J. Arachidonic acid metabolism. Implications of biological chemistry for lung function and diseases. Am. Rev. Resp. Dis. 143:1991;188-203.
    • (1991) Am. Rev. Resp. Dis. , vol.143 , pp. 188-203
    • Holtzman, M.J.1
  • 27
    • 0023679145 scopus 로고
    • 4 and 12-hydroxyeicosatetrenoic acid from alveolar epithelial cell-derived arachidonic acid
    • 4 and 12-hydroxyeicosatetrenoic acid from alveolar epithelial cell-derived arachidonic acid. Am. Rev. Resp. Dis. 138:1988;928-935.
    • (1988) Am. Rev. Resp. Dis. , vol.138 , pp. 928-935
    • Chauncey, J.B.1    Simon, R.2    Peters-Golden, M.3
  • 28
    • 0027223677 scopus 로고
    • Transcellular eicosanoid synthesis in cocultures of alveolar epithelial cells and macrophages
    • Peters-Golden M., Feyssa A. Transcellular eicosanoid synthesis in cocultures of alveolar epithelial cells and macrophages. Am. J. Physiol. 264:1993;L438-L447.
    • (1993) Am. J. Physiol. , vol.264
    • Peters-Golden, M.1    Feyssa, A.2
  • 29
    • 0018139071 scopus 로고
    • Pharmacokinetics of oral acetylcysteine: Absorbtion, binding and metabolism in patients with respiratory disorders
    • Rodenstein D., De Coster A., Gazzaninga A. Pharmacokinetics of oral acetylcysteine: Absorbtion, binding and metabolism in patients with respiratory disorders. Clin. Pharmacok. 3:1978;247-254.
    • (1978) Clin. Pharmacok. , vol.3 , pp. 247-254
    • Rodenstein, D.1    De Coster, A.2    Gazzaninga, A.3
  • 30
    • 0023835113 scopus 로고
    • Pharmacokinetics and bioavailability of reduced and oxidised N-acetylcysteine
    • Olsson B., Johansson M., Gabrielsson J., Bolme P. Pharmacokinetics and bioavailability of reduced and oxidised N-acetylcysteine. Eur. J. Clin. Pharmacol. 34:1988;77-82.
    • (1988) Eur. J. Clin. Pharmacol. , vol.34 , pp. 77-82
    • Olsson, B.1    Johansson, M.2    Gabrielsson, J.3    Bolme, P.4


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