Human glutathione S-transferase-mediated glutathione conjugation of curcumin and efflux of these conjugates in caco-2 cells

Chemical Research in Toxicology

Volumn 20, Issue 12, 2007, Pages 1895-1902

  Usta, Mustafa ^a   Wortelboer, Heleen M ^a   Vervoort, Jacques ^b   Boersma, Marelle G ^b   Rietjens, Ivonne M C M ^b   Van Bladeren, Peter J ^b,c   Cnubben, Nicole H P ^a,b  

^a TNO   (Netherlands)

^b WAGENINGEN UNIVERSITY   (Netherlands)

^c NESTLÉ RESEARCH CENTER   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

CURCUMIN; GLUTATHIONE TRANSFERASE;

ADULT; AGED; ARTICLE; ATOM; CATALYSIS; CELL STRAIN CACO 2; CONJUGATE; DRUG DEGRADATION; DRUG EXCRETION; DRUG STRUCTURE; FEMALE; GLUTATHIONE METABOLISM; HUMAN; HUMAN CELL; HUMAN TISSUE; INTESTINE; INTESTINE EPITHELIUM CELL; LIQUID CHROMATOGRAPHY; LIVER CYTOSOL; MALE; MASS SPECTROMETRY; MONOLAYER CULTURE; PROTON NUCLEAR MAGNETIC RESONANCE;

ADULT; AGED; CACO-2 CELLS; CURCUMIN; CYTOSOL; FEMALE; GLUTATHIONE; GLUTATHIONE TRANSFERASE; HUMANS; INTESTINES; LIVER; MAGNETIC RESONANCE SPECTROSCOPY; MALE; METABOLIC DETOXICATION, PHASE II; MIDDLE AGED; MOLECULAR STRUCTURE;

EID: 38149075378     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx7002245     Document Type: Article

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