Cytokine-mediated induction of anti-apoptotic genes that are linked to nuclear factor kappa-B (NF-κB) signalling in human islets and in a mouse beta cell line

Diabetologia

Volumn 52, Issue 6, 2009, Pages 1092-1101

  Sarkar, S A ^a   Kutlu, B ^b   Velmurugan, K ^c   Kizaka Kondoh, S ^d   Lee, C E ^a   Wong, R ^a   Valentine, A ^a   Davidson, H W ^a   Hutton, J C ^a   Pugazhenthi, S ^c  

^a UNIVERSITY OF COLORADO DENVER   (United States)

^b INSTITUTE FOR SYSTEMS BIOLOGY   (United States)

^c UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^d KYOTO UNIVERSITY   (Japan)

Author keywords

Apoptosis; BIRC3; Cytokines; Human islets; Microarray; NF B; Type 1 diabetes

Indexed keywords

GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 1BETA; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; ARTICLE; BCL2A1 GENE; BIRC3 GENE; CELL CULTURE; CELL LINE; CELL VIABILITY; CFB GENE; CFLAR GENE; CONTROLLED STUDY; CSF1 GENE; CSF2 GENE; CSF3 GENE; CULTURE MEDIUM; CXCL1 GENE; CXCL10 GENE; FAS GENE; GENE; GENE EXPRESSION REGULATION; GENE INDUCTION; HUMAN; HUMAN CELL; ICAM1 GENE; IL1A GENE; IL1B GENE; IL6 GENE; IL8 GENE; INSULIN DEPENDENT DIABETES MELLITUS; LTB GENE; MOUSE; NONHUMAN; NOS2 GENE; OLR1 GENE; PANCREAS ISLET BETA CELL; PLAU GENE; PRIORITY JOURNAL; PROMOTER REGION; PTGS2 GENE; SIGNAL TRANSDUCTION; SOD2 GENE; TAP1 GENE; TNF GENE; TNFAIP GENE; TNFAIP3 GENE; TRAF1 GENE; UPREGULATION;

ANIMALS; CASP8 AND FADD-LIKE APOPTOSIS REGULATING PROTEIN; CELL LINE; CELLS, CULTURED; CYTOKINES; DNA-BINDING PROTEINS; HUMANS; INHIBITOR OF APOPTOSIS PROTEINS; INSULIN-SECRETING CELLS; INTERFERON-GAMMA; INTERLEUKIN-1BETA; ISLETS OF LANGERHANS; MICE; NF-KAPPA B; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROTO-ONCOGENE PROTEINS C-BCL-2; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TNF RECEPTOR-ASSOCIATED FACTOR 1; TUMOR NECROSIS FACTOR-ALPHA;

EID: 67349121629     PISSN: 0012186X     EISSN: 14320428     Source Type: Journal    
DOI: 10.1007/s00125-009-1331-x     Document Type: Article

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