Natural antibodies and complement are endogenous adjuvants for vaccine-induced CD8+ T-cell responses

Nature Medicine

Volumn 9, Issue 10, 2003, Pages 1287-1292

  Stäger, Simona ^a   Alexander, James ^b   Kirby, Alun C ^a   Botto, Marina ^c   Van Rooijen, Nico ^d   Smith, Deborah F ^e   Brombacher, Frank ^f   Kaye, Paul M ^a  

^a LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^b UNIVERSITY OF STRATHCLYDE   (United Kingdom)

^c IMPERIAL COLLEGE LONDON   (United Kingdom)

^d VU UNIVERSITY AMSTERDAM   (Netherlands)

^e WELLCOME TRUST SANGER INSTITUTE   (United Kingdom)

^f UNIVERSITY OF CAPE TOWN   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

CD11B ANTIGEN; CD8 ANTIGEN; GLYCOPROTEIN P 15095; INTERLEUKIN 4; LEISHMANIA VACCINE; RECOMBINANT HYDROPHILIC ACYLATED SURFACE PROTEIN 1; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBODY RESPONSE; ANTIGEN ANTIBODY COMPLEX; ARTICLE; CELLULAR IMMUNITY; COMPLEMENT ACTIVATION; CONTROLLED STUDY; CYTOKINE RELEASE; IMMUNE RESPONSE; IMMUNITY; LEISHMANIA DONOVANI; LONG TERM CARE; MOUSE; NONHUMAN; PHAGOCYTE; PRIORITY JOURNAL; PROTEIN FAMILY; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; VACCINATION; VISCERAL LEISHMANIASIS;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIBODIES; ANTIGENS, CD11B; ANTIGENS, CD11C; ANTIGENS, PROTOZOAN; CD8-POSITIVE T-LYMPHOCYTES; COMPLEMENT ACTIVATION; COMPLEMENT SYSTEM PROTEINS; INTERLEUKIN-12; INTERLEUKIN-4; LEISHMANIASIS, VISCERAL; MICE; MICE, INBRED STRAINS; MICE, KNOCKOUT; PHAGOCYTES; PROTOZOAN PROTEINS; VACCINES;

ANIMALIA; LEISHMANIA DONOVANI; PROTOZOA;

EID: 10744222524     PISSN: 10788956     EISSN: None     Source Type: Journal    
DOI: 10.1038/nm933     Document Type: Article

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