T cells from Leishmania major-susceptible BALB/c mice have a defect in efficiently up-regulating CXCR3 upon activation

Journal of Immunology

Volumn 181, Issue 7, 2008, Pages 4613-4620

  Barbi, Joseph ^a   Brombacher, Frank ^b   Satoskar, Abhay R ^a  

^a OHIO STATE UNIVERSITY   (United States)

^b UNIVERSITY OF CAPE TOWN   (South Africa)

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIBODY; CHEMOKINE RECEPTOR CXCR3; GAMMA INTERFERON; INTERLEUKIN 10; INTERLEUKIN 13; INTERLEUKIN 4; MONOCLONAL ANTIBODY CD28; CXCR3 PROTEIN, MOUSE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BAGG ALBINO MOUSE; C57BL 6 MOUSE; CONTROLLED STUDY; DISEASE COURSE; DOWN REGULATION; INFECTION SENSITIVITY; LEISHMANIA MAJOR; LEISHMANIASIS; LYMPH NODE; LYMPHOCYTOPOIESIS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RECEPTOR UPREGULATION; STRAIN DIFFERENCE; T LYMPHOCYTE ACTIVATION; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; CELL CULTURE; COMPARATIVE STUDY; GENETIC PREDISPOSITION; GENETICS; IMMUNOLOGY; INNATE IMMUNITY; LYMPHOCYTE ACTIVATION; LYMPHOCYTE COUNT; MOUSE MUTANT; PARASITOLOGY; PATHOLOGY; PHYSIOLOGY; SKIN LEISHMANIASIS; SPECIES DIFFERENCE; T LYMPHOCYTE SUBPOPULATION; TH1 CELL; UPREGULATION;

ANIMALS; CELLS, CULTURED; GENETIC PREDISPOSITION TO DISEASE; IMMUNITY, INNATE; LEISHMANIA MAJOR; LEISHMANIASIS, CUTANEOUS; LYMPH NODES; LYMPHOCYTE ACTIVATION; LYMPHOCYTE COUNT; MICE; MICE, INBRED BALB C; MICE, INBRED C57BL; MICE, KNOCKOUT; RECEPTORS, CXCR3; SPECIES SPECIFICITY; T-LYMPHOCYTE SUBSETS; TH1 CELLS; UP-REGULATION;

EID: 58149288680     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.181.7.4613     Document Type: Article

References (26)

1. Murray, H. W., J. D. Berman, C. R. Davies, and N. G. Saravia. 2005. Advances in leishmaniasis. Lancet 366: 1561-1577.
2. Reiner, S. L., and R. M. Locksley. 1995. The regulation of immunity to Leishmania major. Annu. Rev. Immunol. 13: 151-177.
3. + cells are different from TH2 cells. Eur. J. Immunol. 20: 2067-2074.
4. Scott, P. 1991. IFN-γ modulates the early development of Th1 and Th2 responses in a murine model of cutaneous leishmaniasis. J. Immunol. 147: 3149-3155.
5. Lohoff, M., F. Sommer, W. Solbach, and M. Rollinghoff. 1989. Coexistence of antigen-specific TH1 and TH2 cells in genetically susceptible BALB/c mice infected with Leishmania major. Immunobiology 179: 412-421. (Pubitemid 19268315)
6. + lymph node cells during experimental murine leishmaniasis in resistant and susceptible mice. Int. Immunol. 10: 1853-1861.
7. Noben-Trauth, N. 2000. Susceptibility to Leishmania major infection in the absence of IL-4. Immunol. Lett. 75: 41-44.
8. Mohrs, M., C. Holscher, and F. Brombacher. 2000. Interleukin-4 receptor α-deficient BALB/c mice show an unimpaired T helper 2 polarization in response to Leishmania major infection. Infect. Immun. 68: 1773-1780. (Pubitemid 30164798)
9. Rosas, L. E., J. Barbi, B. Lu, Y. Fujiwara, C. Gerard, V. M. Sanders, and A. R. Satoskar. 2005. CXCR3-/- mice mount an efficient Th1 response but fail to control Leishmania major infection. Eur. J. Immunol. 35: 515-523.
10. Bonecchi, R., G. Bianchi, P. P. Bordignon, D. D'Ambrosio, R. Lang, A. Borsatti, S. Sozzani, P. Allavena, P. A. Gray, A. Mantovani, and F. Sinigaglia. 1998. Differential expression of chemokine receptors and chemotactic responsiveness of type 1 T helper cells (Th1s) and Th2s. J. Exp. Med. 187: 129-134. (Pubitemid 28044828)
11. + T cells. Blood 110: 2215-2216.
12. Barbi, J., S. Oghumu, L. E. Rosas, T. Carlson, B. Lu, C. Gerard, C. M. Lezama-Davila, and A. R. Satoskar. 2007. Lack of CXCR3 delays the development of hepatic inflammation but does not impair resistance to Leishmania donovani. J. Infect. Dis. 195: 1713-1717. (Pubitemid 46799230)
13. Yoneyama, H., S. Narumi, Y. Zhang, M. Murai, M. Baggiolini, A. Lanzavecchia, T. Ichida, H. Asakura, and K. Matsushima. 2002. Pivotal role of dendritic cell-derived CXCL10 in the retention of T helper cell 1 lymphocytes in secondary lymph nodes. J. Exp. Med. 195: 1257-1266. (Pubitemid 34564328)
14. Nakajima, C., T. Mukai, N. Yamaguchi, Y. Morimoto, W. R. Park, M. Iwasaki, P. Gao, S. Ono, H. Fujiwara, and T. Hamaoka. 2002. Induction of the chemokine receptor CXCR3 on TCR-stimulated T cells: dependence on the release from persistent TCR-triggering and requirement for IFN-γ stimulation. Eur. J. Immunol. 32: 1792-1801.
15. + T-cell trafficking. Blood 106: 3432-3439.
16. Taqueti, V. R., N. Grabie, R. Colvin, H. Pang, P. Jarolim, A. D. Luster, L. H. Glimcher, and A. H. Lichtman. 2006. T-bet controls pathogenicity of CTLs in the heart by separable effects on migration and effector activity. J. Immunol. 177: 5890-5901.
17. Lighvani, A. A., D. M. Frucht, D. Jankovic, H. Yamane, J. Aliberti, B. D. Hissong, B. V. Nguyen, M. Gadina, A. Sher, W. E. Paul, and J. J. O'Shea. 2001. T-bet is rapidly induced by interferon-γ in lymphoid and myeloid cells. Proc. Natl. Acad. Sci. USA 98: 15137-15142.
18. Albanesi, C., C. Scarponi, S. Sebastiani, A. Cavani, M. Federici, O. De Pità, P. Puddu, and G. Girolomoni. 2000. IL-4 enhances keratinocyte expression of CXCR3 agonistic chemokines. J. Immunol. 165: 1395-1402. (Pubitemid 30604571)
19. Fort, M., R. Lesley, N. Davidson, S. Menon, F. Brombacher, M. Leach, and D. Rennick. 2001. IL-4 exacerbates disease in a Th1 cell transfer model of colitis. J. Immunol. 166: 2793-2800. (Pubitemid 32173520)
20. Kremlev, S. G., and C. Palmer. 2005. Interleukin-10 inhibits endotoxin-induced pro-inflammatory cytokines in microglial cell cultures. J. Neuroimmunol. 162: 71-80. (Pubitemid 40503100)
21. Roque, S., C. Nobrega, R. Appelberg, and M. Correia-Neves. 2007. IL-10 underlies distinct susceptibility of BALB/c and C57BL/6 mice to Mycobacterium avium infection and influences efficacy of antibiotic therapy. J. Immunol. 178: 8028-8035. (Pubitemid 46898074)
22. Jinquan, T., C. Jing, H. H. Jacobi, C. M. Reimert, A. Millner, S. Quan, J. B. Hansen, S. Dissing, H. J. Malling, P. S. Skov, and L. K. Poulsen. 2000. CXCR3 expression and activation of eosinophils: role of IFN-γ-inducible protein-10 and monokine induced by IFN-γ. J. Immunol. 165: 1548-1556. (Pubitemid 30604591)
23. Chen, D., Y. Ding, N. Zhang, B. Schroppel, S. Fu, W. Zang, H. Zhang, W. W. Hancock, and J. S. Bromberg. 2003. Viral IL-10 gene transfer inhibits the expression of multiple chemokine and chemokine receptor genes induced by inflammatory or adaptive immune stimuli. Am. J. Transplant. 3: 1538-1549. (Pubitemid 37541511)
24. -) Th1 cells are the source of IL-10-mediated immune suppression in chronic cutaneous leishmaniasis. J. Exp. Med. 204: 285-297.
25. Yoon, K. C., C. S. De Paiva, H. Qi, Z. Chen, W. J. Farley, D. Q. Li, and S. C. Pflugfelder. 2007. Expression of Th-1 chemokines and chemokine receptors on the ocular surface of C57BL/6 mice: effects of desiccating stress. Invest. Ophthalmol. Visual Sci. 48: 2561-2569.
26. Van den Steen, P. E., K. Deroost, I. V. Aelst, N. Geurts, E. Martens, S. Struyf, C. Q. Nie, D. S. Hansen, P. Matthys, J. V. Damme, and G. Opdenakker. 2008. CXCR3 determines strain susceptibility to murine cerebral malaria by mediating T lymphocyte migration toward IFN-γ-induced chemokines. Eur. J. Immunol. 38: 1082-1095.