메뉴 건너뛰기




Volumn 86, Issue 3, 2009, Pages 198-207

ProtEx™ technology for the generation of novel therapeutic cancer vaccines

Author keywords

[No Author keywords available]

Indexed keywords

CANCER VACCINE; CELL FREE VACCINE; CPG OLIGODEOXYNUCLEOTIDE; DENDRITIC CELL VACCINE; LIPOPOLYSACCHARIDE; PHOSPHORYL LIPID A; RECOMBINANT CARCINOEMBRYONIC ANTIGEN; RECOMBINANT GRANULOCYTE MACROPHAGE COLONY STIMULATING FACTOR; RECOMBINANT MUCIN1; RECOMBINANT SURVIVIN 2B PEPTIDE; TOLL LIKE RECEPTOR AGONIST; TUMOR ANTIGEN; UNCLASSIFIED DRUG; IMMUNOLOGICAL ADJUVANT; TOLL LIKE RECEPTOR;

EID: 67049144607     PISSN: 00144800     EISSN: 10960945     Source Type: Journal    
DOI: 10.1016/j.yexmp.2009.01.010     Document Type: Article
Times cited : (10)

References (125)
  • 1
    • 3142724031 scopus 로고    scopus 로고
    • Toll-like receptor signalling
    • Akira S., and Takeda K. Toll-like receptor signalling. Nat. Rev. Immunol. 4 (2004) 499-511
    • (2004) Nat. Rev. Immunol. , vol.4 , pp. 499-511
    • Akira, S.1    Takeda, K.2
  • 2
    • 32944464648 scopus 로고    scopus 로고
    • Pathogen recognition and innate immunity
    • Akira S., Uematsu S., and Takeuchi O. Pathogen recognition and innate immunity. Cell 124 (2006) 783-801
    • (2006) Cell , vol.124 , pp. 783-801
    • Akira, S.1    Uematsu, S.2    Takeuchi, O.3
  • 3
    • 0032580348 scopus 로고    scopus 로고
    • Human gene therapy
    • Anderson W.F. Human gene therapy. Nature 392 (1998) 25-30
    • (1998) Nature , vol.392 , pp. 25-30
    • Anderson, W.F.1
  • 5
    • 0037226225 scopus 로고    scopus 로고
    • Cardiac allograft acceptance after localized bone marrow transplantation by isolated limb perfusion in nonmyeloablated recipients
    • Askenasy N., Yolcu E.S., Shirwan H., Wang Z., and Farkas D.L. Cardiac allograft acceptance after localized bone marrow transplantation by isolated limb perfusion in nonmyeloablated recipients. Stem. Cells 21 (2003) 200-207
    • (2003) Stem. Cells , vol.21 , pp. 200-207
    • Askenasy, N.1    Yolcu, E.S.2    Shirwan, H.3    Wang, Z.4    Farkas, D.L.5
  • 6
    • 0037465727 scopus 로고    scopus 로고
    • Display of Fas ligand protein on cardiac vasculature as a novel means of regulating allograft rejection
    • Askenasy N., Yolcu E.S., Wang Z., and Shirwan H. Display of Fas ligand protein on cardiac vasculature as a novel means of regulating allograft rejection. Circulation 107 (2003) 1525-1531
    • (2003) Circulation , vol.107 , pp. 1525-1531
    • Askenasy, N.1    Yolcu, E.S.2    Wang, Z.3    Shirwan, H.4
  • 7
    • 13544277369 scopus 로고    scopus 로고
    • Induction of tolerance using Fas ligand: a double-edged immunomodulator
    • Askenasy N., Yolcu E.S., Yaniv I., and Shirwan H. Induction of tolerance using Fas ligand: a double-edged immunomodulator. Blood 105 (2005) 1396-1404
    • (2005) Blood , vol.105 , pp. 1396-1404
    • Askenasy, N.1    Yolcu, E.S.2    Yaniv, I.3    Shirwan, H.4
  • 11
    • 0018817401 scopus 로고
    • The comparative selectivity of adjuvants for humoral and cell-mediated immunity. II. Effect on delayed-type hypersensitivity in the mouse and guinea pig, and cell-mediated immunity to tumour antigens in the mouse of Freund's incomplete and complete adjuvants, alhydrogel, Corynebacterium parvum, Bordetella pertussis, muramyl dipeptide and saponin
    • Bomford R. The comparative selectivity of adjuvants for humoral and cell-mediated immunity. II. Effect on delayed-type hypersensitivity in the mouse and guinea pig, and cell-mediated immunity to tumour antigens in the mouse of Freund's incomplete and complete adjuvants, alhydrogel, Corynebacterium parvum, Bordetella pertussis, muramyl dipeptide and saponin. Clin. Exp. Immunol. 39 (1980) 435-441
    • (1980) Clin. Exp. Immunol. , vol.39 , pp. 435-441
    • Bomford, R.1
  • 12
    • 0842320993 scopus 로고    scopus 로고
    • Costimulatory ligand 4-1BBL (CD137L) as an efficient adjuvant for human antiviral cytotoxic T cell responses
    • Bukczynski J., Wen T., Ellefsen K., Gauldie J., and Watts T.H. Costimulatory ligand 4-1BBL (CD137L) as an efficient adjuvant for human antiviral cytotoxic T cell responses. Proc. Natl. Acad. Sci. U. S. A. 101 (2004) 1291-1296
    • (2004) Proc. Natl. Acad. Sci. U. S. A. , vol.101 , pp. 1291-1296
    • Bukczynski, J.1    Wen, T.2    Ellefsen, K.3    Gauldie, J.4    Watts, T.H.5
  • 13
    • 0035423265 scopus 로고    scopus 로고
    • 4-1BB ligand induces cell division, sustains survival, and enhances effector function of CD4 and CD8 T cells with similar efficacy
    • Cannons J.L., Lau P., Ghumman B., DeBenedette M.A., Yagita H., Okumura K., and Watts T.H. 4-1BB ligand induces cell division, sustains survival, and enhances effector function of CD4 and CD8 T cells with similar efficacy. J. Immunol. 167 (2001) 1313-1324
    • (2001) J. Immunol. , vol.167 , pp. 1313-1324
    • Cannons, J.L.1    Lau, P.2    Ghumman, B.3    DeBenedette, M.A.4    Yagita, H.5    Okumura, K.6    Watts, T.H.7
  • 16
    • 41149158767 scopus 로고
    • End results in Hodgkin's Disease and lymphosarcoma treated by the mixed toxins of Erysipelas and Bacillus prodigiosus, alone or combined with radiation
    • Coley W.B. End results in Hodgkin's Disease and lymphosarcoma treated by the mixed toxins of Erysipelas and Bacillus prodigiosus, alone or combined with radiation. Ann. Surg. 88 (1928) 641-667
    • (1928) Ann. Surg. , vol.88 , pp. 641-667
    • Coley, W.B.1
  • 17
    • 0036467427 scopus 로고    scopus 로고
    • Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice
    • Cretney E., Takeda K., Yagita H., Glaccum M., Peschon J.J., and Smyth M.J. Increased susceptibility to tumor initiation and metastasis in TNF-related apoptosis-inducing ligand-deficient mice. J. Immunol. 168 (2002) 1356-1361
    • (2002) J. Immunol. , vol.168 , pp. 1356-1361
    • Cretney, E.1    Takeda, K.2    Yagita, H.3    Glaccum, M.4    Peschon, J.J.5    Smyth, M.J.6
  • 18
    • 9144274980 scopus 로고    scopus 로고
    • Extra-lymphatic solid tumor growth is not immunologically ignored and results in early induction of antigen-specific T-cell anergy: dominant role of cross-tolerance to tumor antigens
    • Cuenca A., Cheng F., Wang H., Brayer J., Horna P., Gu L., Bien H., Borrello I.M., Levitsky H.I., and Sotomayor E.M. Extra-lymphatic solid tumor growth is not immunologically ignored and results in early induction of antigen-specific T-cell anergy: dominant role of cross-tolerance to tumor antigens. Cancer Res. 63 (2003) 9007-9015
    • (2003) Cancer Res. , vol.63 , pp. 9007-9015
    • Cuenca, A.1    Cheng, F.2    Wang, H.3    Brayer, J.4    Horna, P.5    Gu, L.6    Bien, H.7    Borrello, I.M.8    Levitsky, H.I.9    Sotomayor, E.M.10
  • 20
    • 8444234229 scopus 로고    scopus 로고
    • 4-1BB and OX40 act independently to facilitate robust CD8 and CD4 recall responses
    • Dawicki W., Bertram E.M., Sharpe A.H., and Watts T.H. 4-1BB and OX40 act independently to facilitate robust CD8 and CD4 recall responses. J. Immunol. 173 (2004) 5944-5951
    • (2004) J. Immunol. , vol.173 , pp. 5944-5951
    • Dawicki, W.1    Bertram, E.M.2    Sharpe, A.H.3    Watts, T.H.4
  • 21
    • 48149104076 scopus 로고    scopus 로고
    • Whole-cell cancer vaccination: from autologous to allogeneic tumor- and dendritic cell-based vaccines
    • de Gruijl T.D., van den Eertwegh A.J., Pinedo H.M., and Scheper R.J. Whole-cell cancer vaccination: from autologous to allogeneic tumor- and dendritic cell-based vaccines. Cancer Immunol. Immunother. 57 (2008) 1569-1577
    • (2008) Cancer Immunol. Immunother. , vol.57 , pp. 1569-1577
    • de Gruijl, T.D.1    van den Eertwegh, A.J.2    Pinedo, H.M.3    Scheper, R.J.4
  • 22
    • 34247554229 scopus 로고    scopus 로고
    • Cutting edge: lipopolysaccharide induces IL-10-producing regulatory CD4+ T cells that suppress the CD8+ T cell response
    • den Haan J.M., Kraal G., and Bevan M.J. Cutting edge: lipopolysaccharide induces IL-10-producing regulatory CD4+ T cells that suppress the CD8+ T cell response. J. Immunol. 178 (2007) 5429-5433
    • (2007) J. Immunol. , vol.178 , pp. 5429-5433
    • den Haan, J.M.1    Kraal, G.2    Bevan, M.J.3
  • 23
    • 0028500836 scopus 로고
    • Enhanced in vivo growth and resistance to rejection of tumor cells expressing dominant negative IFN gamma receptors
    • Dighe A.S., Richards E., Old L.J., and Schreiber R.D. Enhanced in vivo growth and resistance to rejection of tumor cells expressing dominant negative IFN gamma receptors. Immunity 1 (1994) 447-456
    • (1994) Immunity , vol.1 , pp. 447-456
    • Dighe, A.S.1    Richards, E.2    Old, L.J.3    Schreiber, R.D.4
  • 25
    • 4143141823 scopus 로고    scopus 로고
    • The immunobiology of cancer immunosurveillance and immunoediting
    • Dunn G.P., Old L.J., and Schreiber R.D. The immunobiology of cancer immunosurveillance and immunoediting. Immunity 21 (2004) 137-148
    • (2004) Immunity , vol.21 , pp. 137-148
    • Dunn, G.P.1    Old, L.J.2    Schreiber, R.D.3
  • 26
    • 34249785092 scopus 로고    scopus 로고
    • CD4+CD25+ T regulatory cells dominate multiple immune evasion mechanisms in early but not late phases of tumor development in a B cell lymphoma model
    • Elpek K.G., Lacelle C., Singh N.P., Yolcu E.S., and Shirwan H. CD4+CD25+ T regulatory cells dominate multiple immune evasion mechanisms in early but not late phases of tumor development in a B cell lymphoma model. J. Immunol. 178 (2007) 6840-6848
    • (2007) J. Immunol. , vol.178 , pp. 6840-6848
    • Elpek, K.G.1    Lacelle, C.2    Singh, N.P.3    Yolcu, E.S.4    Shirwan, H.5
  • 27
    • 38849108168 scopus 로고    scopus 로고
    • Ex vivo expansion of CD4+CD25+FoxP3+ T regulatory cells based on synergy between IL-2 and 4-1BB signaling
    • Elpek K.G., Yolcu E.S., Franke D.D., Lacelle C., Schabowsky R.H., and Shirwan H. Ex vivo expansion of CD4+CD25+FoxP3+ T regulatory cells based on synergy between IL-2 and 4-1BB signaling. J. Immunol. 179 (2007) 7295-7304
    • (2007) J. Immunol. , vol.179 , pp. 7295-7304
    • Elpek, K.G.1    Yolcu, E.S.2    Franke, D.D.3    Lacelle, C.4    Schabowsky, R.H.5    Shirwan, H.6
  • 29
    • 33947149074 scopus 로고    scopus 로고
    • A novel multimeric form of FasL modulates the ability of diabetogenic T cells to mediate type 1 diabetes in an adoptive transfer model
    • Franke D.D., Yolcu E.S., Alard P., Kosiewicz M.M., and Shirwan H. A novel multimeric form of FasL modulates the ability of diabetogenic T cells to mediate type 1 diabetes in an adoptive transfer model. Mol. Immunol. 44 (2007) 2884-2892
    • (2007) Mol. Immunol. , vol.44 , pp. 2884-2892
    • Franke, D.D.1    Yolcu, E.S.2    Alard, P.3    Kosiewicz, M.M.4    Shirwan, H.5
  • 32
    • 33845905223 scopus 로고    scopus 로고
    • Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling
    • Gavin A.L., Hoebe K., Duong B., Ota T., Martin C., Beutler B., and Nemazee D. Adjuvant-enhanced antibody responses in the absence of toll-like receptor signaling. Science 314 (2006) 1936-1938
    • (2006) Science , vol.314 , pp. 1936-1938
    • Gavin, A.L.1    Hoebe, K.2    Duong, B.3    Ota, T.4    Martin, C.5    Beutler, B.6    Nemazee, D.7
  • 35
    • 41549166837 scopus 로고    scopus 로고
    • A novel vaccine for cervical cancer: quadrivalent human papillomavirus (types 6, 11, 16 and 18) recombinant vaccine (Gardasil)
    • Govan V.A. A novel vaccine for cervical cancer: quadrivalent human papillomavirus (types 6, 11, 16 and 18) recombinant vaccine (Gardasil). Ther. Clin. Risk Manag. 4 (2008) 65-70
    • (2008) Ther. Clin. Risk Manag. , vol.4 , pp. 65-70
    • Govan, V.A.1
  • 37
    • 0038658878 scopus 로고    scopus 로고
    • LIGHT-HVEM signaling and the regulation of T cell-mediated immunity
    • Granger S.W., and Rickert S. LIGHT-HVEM signaling and the regulation of T cell-mediated immunity. Cytokine Growth Factor Rev. 14 (2003) 289-296
    • (2003) Cytokine Growth Factor Rev. , vol.14 , pp. 289-296
    • Granger, S.W.1    Rickert, S.2
  • 38
    • 0025288944 scopus 로고
    • Avidin and streptavidin
    • Green N.M. Avidin and streptavidin. Methods Enzymol. 184 (1990) 51-67
    • (1990) Methods Enzymol. , vol.184 , pp. 51-67
    • Green, N.M.1
  • 39
    • 0024328379 scopus 로고
    • Different T helper cell subsets elicited in mice utilizing two different adjuvant vehicles: the role of endogenous interleukin 1 in proliferative responses
    • Grun J.L., and Maurer P.H. Different T helper cell subsets elicited in mice utilizing two different adjuvant vehicles: the role of endogenous interleukin 1 in proliferative responses. Cell Immunol. 121 (1989) 134-145
    • (1989) Cell Immunol. , vol.121 , pp. 134-145
    • Grun, J.L.1    Maurer, P.H.2
  • 40
    • 11944262611 scopus 로고    scopus 로고
    • A CD80-transfected human breast cancer cell variant induces HER-2/neu-specific T cells in HLA-A*02-matched situations in vitro as well as in vivo
    • Gückel B., Stumm S., Rentzsch C., Marmé A., Mannhardt G., and Wallwiener D. A CD80-transfected human breast cancer cell variant induces HER-2/neu-specific T cells in HLA-A*02-matched situations in vitro as well as in vivo. Cancer Immunol. Immunother. 54 2 (2005) 129-140
    • (2005) Cancer Immunol. Immunother. , vol.54 , Issue.2 , pp. 129-140
    • Gückel, B.1    Stumm, S.2    Rentzsch, C.3    Marmé, A.4    Mannhardt, G.5    Wallwiener, D.6
  • 42
    • 0036063949 scopus 로고    scopus 로고
    • Administration of either anti-CD40 or interleukin-12 following lethal total body irradiation induces acute lethal toxicity affecting the gut
    • Hixon J.A., Anver M.R., Blazar B.R., Panoskaltsis-Mortari A., Wiltrout R.H., and Murphy W.J. Administration of either anti-CD40 or interleukin-12 following lethal total body irradiation induces acute lethal toxicity affecting the gut. Biol. Blood Marrow Transplant. 8 (2002) 316-325
    • (2002) Biol. Blood Marrow Transplant. , vol.8 , pp. 316-325
    • Hixon, J.A.1    Anver, M.R.2    Blazar, B.R.3    Panoskaltsis-Mortari, A.4    Wiltrout, R.H.5    Murphy, W.J.6
  • 44
    • 40849126694 scopus 로고    scopus 로고
    • Clinical phase I intratumoral administration of two recombinant ALVAC canarypox viruses expressing human granulocyte-macrophage colony-stimulating factor or interleukin-2: the transgene determines the composition of the inflammatory infiltrate
    • Hofbauer G.F., Baur T., Bonnet M.C., Tartour E., Burg G., Berinstein N.L., and Dummer R. Clinical phase I intratumoral administration of two recombinant ALVAC canarypox viruses expressing human granulocyte-macrophage colony-stimulating factor or interleukin-2: the transgene determines the composition of the inflammatory infiltrate. Melanoma Res. 18 (2008) 104-111
    • (2008) Melanoma Res. , vol.18 , pp. 104-111
    • Hofbauer, G.F.1    Baur, T.2    Bonnet, M.C.3    Tartour, E.4    Burg, G.5    Berinstein, N.L.6    Dummer, R.7
  • 46
    • 31544446571 scopus 로고    scopus 로고
    • Gr-1+CD115+ immature myeloid suppressor cells mediate the development of tumor-induced T regulatory cells and T-cell anergy in tumor-bearing host
    • Huang B., Pan P.Y., Li Q., Sato A.I., Levy D.E., Bromberg J., Divino C.M., and Chen S.H. Gr-1+CD115+ immature myeloid suppressor cells mediate the development of tumor-induced T regulatory cells and T-cell anergy in tumor-bearing host. Cancer Res. 66 (2006) 1123-1131
    • (2006) Cancer Res. , vol.66 , pp. 1123-1131
    • Huang, B.1    Pan, P.Y.2    Li, Q.3    Sato, A.I.4    Levy, D.E.5    Bromberg, J.6    Divino, C.M.7    Chen, S.H.8
  • 48
    • 34250206008 scopus 로고    scopus 로고
    • Toll or toll-free adjuvant path toward the optimal vaccine development
    • Ishii K.J., and Akira S. Toll or toll-free adjuvant path toward the optimal vaccine development. J. Clin. Immunol. 27 (2007) 363-371
    • (2007) J. Clin. Immunol. , vol.27 , pp. 363-371
    • Ishii, K.J.1    Akira, S.2
  • 51
    • 0034901095 scopus 로고    scopus 로고
    • Survival of tumor cells in stem cell preparations and bone marrow of patients with high-risk or metastatic breast cancer after receiving dose-intensive or high-dose chemotherapy
    • Kasimir-Bauer S., Mayer S., Bojko P., Borquez D., Neumann R., and Seeber S. Survival of tumor cells in stem cell preparations and bone marrow of patients with high-risk or metastatic breast cancer after receiving dose-intensive or high-dose chemotherapy. Clin. Cancer Res. 7 6 (2001) 1582-1589
    • (2001) Clin. Cancer Res. , vol.7 , Issue.6 , pp. 1582-1589
    • Kasimir-Bauer, S.1    Mayer, S.2    Bojko, P.3    Borquez, D.4    Neumann, R.5    Seeber, S.6
  • 53
    • 0033954331 scopus 로고    scopus 로고
    • CD137 (ILA/4-1BB), expressed by primary human monocytes, induces monocyte activation and apoptosis of B lymphocytes
    • Kienzle G., and von Kempis J. CD137 (ILA/4-1BB), expressed by primary human monocytes, induces monocyte activation and apoptosis of B lymphocytes. Int. Immunol. 12 (2000) 73-82
    • (2000) Int. Immunol. , vol.12 , pp. 73-82
    • Kienzle, G.1    von Kempis, J.2
  • 54
    • 33745542998 scopus 로고    scopus 로고
    • Generation of a multimeric form of CD40L with potent immunostimulatory activity using streptavidin as a chaperon
    • Kilinc M.O., Mukundan L., Yolcu E.S., Singh N.P., Suttles J., and Shirwan H. Generation of a multimeric form of CD40L with potent immunostimulatory activity using streptavidin as a chaperon. Exp. Mol. Pathol. 80 (2006) 252-261
    • (2006) Exp. Mol. Pathol. , vol.80 , pp. 252-261
    • Kilinc, M.O.1    Mukundan, L.2    Yolcu, E.S.3    Singh, N.P.4    Suttles, J.5    Shirwan, H.6
  • 55
    • 33745306869 scopus 로고    scopus 로고
    • IL-2 immunotoxin therapy modulates tumor-associated regulatory T cells and leads to lasting immune-mediated rejection of breast cancers in neu-transgenic mice
    • Knutson K.L., Dang Y., Lu H., Lukas J., Almand B., Gad E., Azeke E., and Disis M.L. IL-2 immunotoxin therapy modulates tumor-associated regulatory T cells and leads to lasting immune-mediated rejection of breast cancers in neu-transgenic mice. J. Immunol. 177 (2006) 84-91
    • (2006) J. Immunol. , vol.177 , pp. 84-91
    • Knutson, K.L.1    Dang, Y.2    Lu, H.3    Lukas, J.4    Almand, B.5    Gad, E.6    Azeke, E.7    Disis, M.L.8
  • 56
    • 0036098003 scopus 로고    scopus 로고
    • Immunization of cancer patients with a HER-2/neu, HLA-A2 peptide, p369-377, results in short-lived peptide-specific immunity
    • Knutson K.L., Schiffman K., Cheever M.A., and Disis M.L. Immunization of cancer patients with a HER-2/neu, HLA-A2 peptide, p369-377, results in short-lived peptide-specific immunity. Clin. Cancer Res. 8 (2002) 1014-1018
    • (2002) Clin. Cancer Res. , vol.8 , pp. 1014-1018
    • Knutson, K.L.1    Schiffman, K.2    Cheever, M.A.3    Disis, M.L.4
  • 57
    • 33947187647 scopus 로고    scopus 로고
    • Toll-free vaccines?
    • Krieg A.M. Toll-free vaccines?. Nat. Biotechnol. 25 (2007) 303-305
    • (2007) Nat. Biotechnol. , vol.25 , pp. 303-305
    • Krieg, A.M.1
  • 58
  • 59
    • 0346995358 scopus 로고    scopus 로고
    • Lipopolysaccharide preferentially induces 4-1BB ligand expression on human monocyte-derived dendritic cells
    • Lee P.K., Chang C.J., and Lin C.M. Lipopolysaccharide preferentially induces 4-1BB ligand expression on human monocyte-derived dendritic cells. Immunol. Lett. 90 (2003) 215-221
    • (2003) Immunol. Lett. , vol.90 , pp. 215-221
    • Lee, P.K.1    Chang, C.J.2    Lin, C.M.3
  • 64
    • 0036195161 scopus 로고    scopus 로고
    • CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor
    • McHugh R.S., Whitters M.J., Piccirillo C.A., Young D.A., Shevach E.M., Collins M., and Byrne M.C. CD4(+)CD25(+) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor. Immunity 16 (2002) 311-323
    • (2002) Immunity , vol.16 , pp. 311-323
    • McHugh, R.S.1    Whitters, M.J.2    Piccirillo, C.A.3    Young, D.A.4    Shevach, E.M.5    Collins, M.6    Byrne, M.C.7
  • 65
    • 36048962961 scopus 로고    scopus 로고
    • How do adjuvants work? Important considerations for new generation adjuvants
    • McKee A.S., Munks M.W., and Marrack P. How do adjuvants work? Important considerations for new generation adjuvants. Immunity 27 (2007) 687-690
    • (2007) Immunity , vol.27 , pp. 687-690
    • McKee, A.S.1    Munks, M.W.2    Marrack, P.3
  • 67
    • 27144552597 scopus 로고    scopus 로고
    • Cutting edge: CpG oligonucleotides induce splenic CD19+ dendritic cells to acquire potent indoleamine 2,3-dioxygenase-dependent T cell regulatory functions via IFN Type 1 signaling
    • Mellor A.L., Baban B., Chandler P.R., Manlapat A., Kahler D.J., and Munn D.H. Cutting edge: CpG oligonucleotides induce splenic CD19+ dendritic cells to acquire potent indoleamine 2,3-dioxygenase-dependent T cell regulatory functions via IFN Type 1 signaling. J. Immunol. 175 (2005) 5601-5605
    • (2005) J. Immunol. , vol.175 , pp. 5601-5605
    • Mellor, A.L.1    Baban, B.2    Chandler, P.R.3    Manlapat, A.4    Kahler, D.J.5    Munn, D.H.6
  • 68
    • 37549034962 scopus 로고    scopus 로고
    • B cell intrinsic TLR signals amplify but are not required for humoral immunity
    • Meyer-Bahlburg A., Khim S., and Rawlings D.J. B cell intrinsic TLR signals amplify but are not required for humoral immunity. J. Exp. Med. 204 (2007) 3095-3101
    • (2007) J. Exp. Med. , vol.204 , pp. 3095-3101
    • Meyer-Bahlburg, A.1    Khim, S.2    Rawlings, D.J.3
  • 69
    • 0037103147 scopus 로고    scopus 로고
    • 4-1BB-specific monoclonal antibody promotes the generation of tumor-specific immune responses by direct activation of CD8 T cells in a CD40-dependent manner
    • Miller R.E., Jones J., Le T., Whitmore J., Boiani N., Gliniak B., and Lynch D.H. 4-1BB-specific monoclonal antibody promotes the generation of tumor-specific immune responses by direct activation of CD8 T cells in a CD40-dependent manner. J. Immunol. 169 (2002) 1792-1800
    • (2002) J. Immunol. , vol.169 , pp. 1792-1800
    • Miller, R.E.1    Jones, J.2    Le, T.3    Whitmore, J.4    Boiani, N.5    Gliniak, B.6    Lynch, D.H.7
  • 70
    • 4644327023 scopus 로고    scopus 로고
    • Human plasmacytoid dendritic cells activated by CpG oligodeoxynucleotides induce the generation of CD4+CD25+ regulatory T cells
    • Moseman E.A., Liang X., Dawson A.J., Panoskaltsis-Mortari A., Krieg A.M., Liu Y.J., Blazar B.R., and Chen W. Human plasmacytoid dendritic cells activated by CpG oligodeoxynucleotides induce the generation of CD4+CD25+ regulatory T cells. J. Immunol. 173 (2004) 4433-4442
    • (2004) J. Immunol. , vol.173 , pp. 4433-4442
    • Moseman, E.A.1    Liang, X.2    Dawson, A.J.3    Panoskaltsis-Mortari, A.4    Krieg, A.M.5    Liu, Y.J.6    Blazar, B.R.7    Chen, W.8
  • 71
    • 31544451599 scopus 로고    scopus 로고
    • Combined CD137 (4-1BB) and adjuvant therapy generates a developing pool of peptide-specific CD8 memory T cells
    • Myers L., Lee S.W., Rossi R.J., Lefrancois L., Kwon B.S., Mittler R.S., Croft M., and Vella A.T. Combined CD137 (4-1BB) and adjuvant therapy generates a developing pool of peptide-specific CD8 memory T cells. Int. Immunol. 18 (2006) 325-333
    • (2006) Int. Immunol. , vol.18 , pp. 325-333
    • Myers, L.1    Lee, S.W.2    Rossi, R.J.3    Lefrancois, L.4    Kwon, B.S.5    Mittler, R.S.6    Croft, M.7    Vella, A.T.8
  • 73
    • 33947696816 scopus 로고    scopus 로고
    • Cytokine-mediated disruption of lymphocyte trafficking, hemopoiesis, and induction of lymphopenia, anemia, and thrombocytopenia in anti-CD137-treated mice
    • Niu L., Strahotin S., Hewes B., Zhang B., Zhang Y., Archer D., Spencer T., Dillehay D., Kwon B., Chen L., Vella A.T., and Mittler R.S. Cytokine-mediated disruption of lymphocyte trafficking, hemopoiesis, and induction of lymphopenia, anemia, and thrombocytopenia in anti-CD137-treated mice. J. Immunol. 178 (2007) 4194-4213
    • (2007) J. Immunol. , vol.178 , pp. 4194-4213
    • Niu, L.1    Strahotin, S.2    Hewes, B.3    Zhang, B.4    Zhang, Y.5    Archer, D.6    Spencer, T.7    Dillehay, D.8    Kwon, B.9    Chen, L.10    Vella, A.T.11    Mittler, R.S.12
  • 74
    • 40449127743 scopus 로고
    • Action of bacterial polysaccharide on tumors. III. Repeated responses of sarcoma 37, in tolerant mice, to Serratia marcescens endotoxin
    • O'Malley W.E., Achinstein B., and Shear M.J. Action of bacterial polysaccharide on tumors. III. Repeated responses of sarcoma 37, in tolerant mice, to Serratia marcescens endotoxin. Cancer Res. 23 (1963) 890-895
    • (1963) Cancer Res. , vol.23 , pp. 890-895
    • O'Malley, W.E.1    Achinstein, B.2    Shear, M.J.3
  • 75
    • 0022369998 scopus 로고
    • Tumor necrosis factor (TNF)
    • Old L.J. Tumor necrosis factor (TNF). Science 230 (1985) 630-632
    • (1985) Science , vol.230 , pp. 630-632
    • Old, L.J.1
  • 77
    • 0036658720 scopus 로고    scopus 로고
    • CD137 is expressed by follicular dendritic cells and costimulates B lymphocyte activation in germinal centers
    • Pauly S., Broll K., Wittmann M., Giegerich G., and Schwarz H. CD137 is expressed by follicular dendritic cells and costimulates B lymphocyte activation in germinal centers. J. Leukoc. Biol. 72 (2002) 35-42
    • (2002) J. Leukoc. Biol. , vol.72 , pp. 35-42
    • Pauly, S.1    Broll, K.2    Wittmann, M.3    Giegerich, G.4    Schwarz, H.5
  • 78
    • 0033853911 scopus 로고    scopus 로고
    • Post-transplant malignancy: the role of immunosuppression
    • Penn I. Post-transplant malignancy: the role of immunosuppression. Drug Saf. 23 (2000) 101-113
    • (2000) Drug Saf. , vol.23 , pp. 101-113
    • Penn, I.1
  • 79
    • 29244444176 scopus 로고    scopus 로고
    • Production of recombinant human trimeric CD137L (4-1BBL). Cross-linking is essential to its T cell co-stimulation activity
    • Rabu C., Quemener A., Jacques Y., Echasserieau K., Vusio P., and Lang F. Production of recombinant human trimeric CD137L (4-1BBL). Cross-linking is essential to its T cell co-stimulation activity. J. Biol. Chem. 280 (2005) 41472-41481
    • (2005) J. Biol. Chem. , vol.280 , pp. 41472-41481
    • Rabu, C.1    Quemener, A.2    Jacques, Y.3    Echasserieau, K.4    Vusio, P.5    Lang, F.6
  • 82
    • 0032776933 scopus 로고    scopus 로고
    • Interleukin-10: a cytokine used by tumors to escape immunosurveillance
    • Salazar-Onfray F. Interleukin-10: a cytokine used by tumors to escape immunosurveillance. Med. Oncol. 16 (1999) 86-94
    • (1999) Med. Oncol. , vol.16 , pp. 86-94
    • Salazar-Onfray, F.1
  • 83
    • 33846319348 scopus 로고    scopus 로고
    • The innate signaling of dangers and the dangers of innate signaling
    • Sansonetti P.J. The innate signaling of dangers and the dangers of innate signaling. Nat. Immunol. 7 (2006) 1237-1242
    • (2006) Nat. Immunol. , vol.7 , pp. 1237-1242
    • Sansonetti, P.J.1
  • 84
    • 51449095355 scopus 로고    scopus 로고
    • Vaccination of fiber-modified adenovirus-transfected dendritic cells to express HER-2/neu stimulates efficient HER-2/neu-specific humoral and CTL responses and reduces breast carcinogenesis in transgenic mice
    • Sas S., Chan T., Sami A., El-Gayed A., and Xiang J. Vaccination of fiber-modified adenovirus-transfected dendritic cells to express HER-2/neu stimulates efficient HER-2/neu-specific humoral and CTL responses and reduces breast carcinogenesis in transgenic mice. Cancer Gene Ther. 15 (2008) 655-666
    • (2008) Cancer Gene Ther. , vol.15 , pp. 655-666
    • Sas, S.1    Chan, T.2    Sami, A.3    El-Gayed, A.4    Xiang, J.5
  • 87
    • 0033827817 scopus 로고    scopus 로고
    • Antigen-processing machinery breakdown and tumor growth
    • Seliger B., Maeurer M.J., and Ferrone S. Antigen-processing machinery breakdown and tumor growth. Immunol. Today 21 (2000) 455-464
    • (2000) Immunol. Today , vol.21 , pp. 455-464
    • Seliger, B.1    Maeurer, M.J.2    Ferrone, S.3
  • 88
    • 0035953308 scopus 로고    scopus 로고
    • IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity
    • Shankaran V., Ikeda H., Bruce A.T., White J.M., Swanson P.E., Old L.J., and Schreiber R.D. IFNgamma and lymphocytes prevent primary tumour development and shape tumour immunogenicity. Nature 410 (2001) 1107-1111
    • (2001) Nature , vol.410 , pp. 1107-1111
    • Shankaran, V.1    Ikeda, H.2    Bruce, A.T.3    White, J.M.4    Swanson, P.E.5    Old, L.J.6    Schreiber, R.D.7
  • 89
    • 33645450748 scopus 로고    scopus 로고
    • Primary tumor cells resected from cancer patients and decorated with a novel form of CD80 protein serve as effective antigen-presenting cells for the induction of autologous T cell immune responses ex vivo
    • Singh N.P., Miller R.W., Yolcu E.S., Kilinc M.O., Oechsli M., Huseby R., Taylor D.D., Perry M.T., Larocca R.V., and Shirwan H. Primary tumor cells resected from cancer patients and decorated with a novel form of CD80 protein serve as effective antigen-presenting cells for the induction of autologous T cell immune responses ex vivo. Hum. Gene Ther. 17 (2006) 334-346
    • (2006) Hum. Gene Ther. , vol.17 , pp. 334-346
    • Singh, N.P.1    Miller, R.W.2    Yolcu, E.S.3    Kilinc, M.O.4    Oechsli, M.5    Huseby, R.6    Taylor, D.D.7    Perry, M.T.8    Larocca, R.V.9    Shirwan, H.10
  • 90
    • 29744450088 scopus 로고    scopus 로고
    • ProtEx: a novel technology to display exogenous proteins on the cell surface for immunomodulation
    • Singh N.P., Yolcu E.S., Askenasy N., and Shirwan H. ProtEx: a novel technology to display exogenous proteins on the cell surface for immunomodulation. Ann. N. Y. Acad. Sci. 1056 (2005) 344-358
    • (2005) Ann. N. Y. Acad. Sci. , vol.1056 , pp. 344-358
    • Singh, N.P.1    Yolcu, E.S.2    Askenasy, N.3    Shirwan, H.4
  • 91
  • 92
    • 33646755569 scopus 로고    scopus 로고
    • Cancer immunosurveillance and immunoediting: the roles of immunity in suppressing tumor development and shaping tumor immunogenicity
    • Smyth M.J., Dunn G.P., and Schreiber R.D. Cancer immunosurveillance and immunoediting: the roles of immunity in suppressing tumor development and shaping tumor immunogenicity. Adv. Immunol. 90 (2006) 1-50
    • (2006) Adv. Immunol. , vol.90 , pp. 1-50
    • Smyth, M.J.1    Dunn, G.P.2    Schreiber, R.D.3
  • 97
    • 0034973345 scopus 로고    scopus 로고
    • Therapeutic antitumor response to cervical cancer in mice immunized with U14 vaccines transfected with costimulatory B7 gene
    • Tao G., Hu J., Zou H., Lin Q., Liu F., Wu Y., and Sun Q. Therapeutic antitumor response to cervical cancer in mice immunized with U14 vaccines transfected with costimulatory B7 gene. Chin. Med. J. (Engl.) 114 (2001) 623-627
    • (2001) Chin. Med. J. (Engl.) , vol.114 , pp. 623-627
    • Tao, G.1    Hu, J.2    Zou, H.3    Lin, Q.4    Liu, F.5    Wu, Y.6    Sun, Q.7
  • 98
    • 0027392843 scopus 로고
    • Tumor rejection after direct costimulation of CD8+ T cells by B7-transfected melanoma cells
    • Townsend S.E., and Allison J.P. Tumor rejection after direct costimulation of CD8+ T cells by B7-transfected melanoma cells. Science 259 (1993) 368-370
    • (1993) Science , vol.259 , pp. 368-370
    • Townsend, S.E.1    Allison, J.P.2
  • 100
    • 2542497798 scopus 로고    scopus 로고
    • Durable carcinoembryonic antigen (CEA)-specific humoral and cellular immune responses in colorectal carcinoma patients vaccinated with recombinant CEA and granulocyte/macrophage colony-stimulating factor
    • Ullenhag G.J., Frodin J.E., Jeddi-Tehrani M., Strigard K., Eriksson E., Samanci A., Choudhury A., Nilsson B., Rossmann E.D., Mosolits S., and Mellstedt H. Durable carcinoembryonic antigen (CEA)-specific humoral and cellular immune responses in colorectal carcinoma patients vaccinated with recombinant CEA and granulocyte/macrophage colony-stimulating factor. Clin. Cancer Res. 10 (2004) 3273-3281
    • (2004) Clin. Cancer Res. , vol.10 , pp. 3273-3281
    • Ullenhag, G.J.1    Frodin, J.E.2    Jeddi-Tehrani, M.3    Strigard, K.4    Eriksson, E.5    Samanci, A.6    Choudhury, A.7    Nilsson, B.8    Rossmann, E.D.9    Mosolits, S.10    Mellstedt, H.11
  • 103
    • 0020173287 scopus 로고
    • Protection against a nonimmunogenic mouse leukemia by an immunogenic variant obtained by mutagenesis
    • Van P.A., and Boon T. Protection against a nonimmunogenic mouse leukemia by an immunogenic variant obtained by mutagenesis. Proc. Natl. Acad. Sci. U.S.A. 79 (1982) 4718-4722
    • (1982) Proc. Natl. Acad. Sci. U.S.A. , vol.79 , pp. 4718-4722
    • Van, P.A.1    Boon, T.2
  • 106
    • 39649103677 scopus 로고    scopus 로고
    • Differential costimulation through CD137 (4-1BB) restores proliferation of human virus-specific "effector memory" (CD28(-) CD45RA(HI)) CD8(+) T cells
    • Waller E.C., McKinney N., Hicks R., Carmichael A.J., Sissons J.G., and Wills M.R. Differential costimulation through CD137 (4-1BB) restores proliferation of human virus-specific "effector memory" (CD28(-) CD45RA(HI)) CD8(+) T cells. Blood 110 (2007) 4360-4366
    • (2007) Blood , vol.110 , pp. 4360-4366
    • Waller, E.C.1    McKinney, N.2    Hicks, R.3    Carmichael, A.J.4    Sissons, J.G.5    Wills, M.R.6
  • 108
    • 17644389199 scopus 로고    scopus 로고
    • TNF/TNFR family members in costimulation of T cell responses
    • Watts T.H. TNF/TNFR family members in costimulation of T cell responses. Annu. Rev. Immunol. 23 (2005) 23-68
    • (2005) Annu. Rev. Immunol. , vol.23 , pp. 23-68
    • Watts, T.H.1
  • 110
    • 38449107219 scopus 로고    scopus 로고
    • Targeting molecular and cellular inhibitory mechanisms for improvement of antitumor memory responses reactivated by tumor cell vaccine
    • Webster W.S., Thompson R.H., Harris K.J., Frigola X., Kuntz S., Inman B.A., and Dong H. Targeting molecular and cellular inhibitory mechanisms for improvement of antitumor memory responses reactivated by tumor cell vaccine. J. Immunol. 179 (2007) 2860-2869
    • (2007) J. Immunol. , vol.179 , pp. 2860-2869
    • Webster, W.S.1    Thompson, R.H.2    Harris, K.J.3    Frigola, X.4    Kuntz, S.5    Inman, B.A.6    Dong, H.7
  • 114
    • 0037108355 scopus 로고    scopus 로고
    • Signaling through NK cell-associated CD137 promotes both helper function for CD8+ cytolytic T cells and responsiveness to IL-2 but not cytolytic activity
    • Wilcox R.A., Tamada K., Strome S.E., and Chen L. Signaling through NK cell-associated CD137 promotes both helper function for CD8+ cytolytic T cells and responsiveness to IL-2 but not cytolytic activity. J. Immunol. 169 (2002) 4230-4236
    • (2002) J. Immunol. , vol.169 , pp. 4230-4236
    • Wilcox, R.A.1    Tamada, K.2    Strome, S.E.3    Chen, L.4
  • 115
    • 67349253964 scopus 로고    scopus 로고
    • Experimental study of specific immunotherapy induced by H22 autologous tumor as whole tumor cell vaccine
    • Sep 18. [Epub ahead of print]
    • Yang W., Guo C., Liu Q.G., and Pan C. Experimental study of specific immunotherapy induced by H22 autologous tumor as whole tumor cell vaccine. Biomed. Pharmacother. (2008) Sep 18. [Epub ahead of print]
    • (2008) Biomed. Pharmacother.
    • Yang, W.1    Guo, C.2    Liu, Q.G.3    Pan, C.4
  • 116
    • 33646422454 scopus 로고    scopus 로고
    • Intratumoral CD4+CD25+ regulatory T-cell-mediated suppression of infiltrating CD4+ T cells in B-cell non-Hodgkin lymphoma
    • Yang Z.Z., Novak A.J., Stenson M.J., Witzig T.E., and Ansell S.M. Intratumoral CD4+CD25+ regulatory T-cell-mediated suppression of infiltrating CD4+ T cells in B-cell non-Hodgkin lymphoma. Blood 107 (2006) 3639-3646
    • (2006) Blood , vol.107 , pp. 3639-3646
    • Yang, Z.Z.1    Novak, A.J.2    Stenson, M.J.3    Witzig, T.E.4    Ansell, S.M.5
  • 117
    • 18744416830 scopus 로고    scopus 로고
    • Cell membrane modification for rapid display of proteins as a novel means of immunomodulation: FasL-decorated cells prevent islet graft rejection
    • Yolcu E.S., Askenasy N., Singh N.P., Cherradi S.E., and Shirwan H. Cell membrane modification for rapid display of proteins as a novel means of immunomodulation: FasL-decorated cells prevent islet graft rejection. Immunity 17 (2002) 795-808
    • (2002) Immunity , vol.17 , pp. 795-808
    • Yolcu, E.S.1    Askenasy, N.2    Singh, N.P.3    Cherradi, S.E.4    Shirwan, H.5
  • 118
    • 49049110769 scopus 로고    scopus 로고
    • Induction of tolerance to cardiac allografts using donor splenocytes engineered to display on their surface an exogenous fas ligand protein
    • Yolcu E.S., Gu X., Lacelle C., Zhao H., Bandura-Morgan L., Askenasy N., and Shirwan H. Induction of tolerance to cardiac allografts using donor splenocytes engineered to display on their surface an exogenous fas ligand protein. J. Immunol. 181 (2008) 931-939
    • (2008) J. Immunol. , vol.181 , pp. 931-939
    • Yolcu, E.S.1    Gu, X.2    Lacelle, C.3    Zhao, H.4    Bandura-Morgan, L.5    Askenasy, N.6    Shirwan, H.7
  • 119
    • 49949152063 scopus 로고    scopus 로고
    • Targeting tumors with LIGHT to generate metastasis-clearing immunity
    • Yu P., and Fu Y.X. Targeting tumors with LIGHT to generate metastasis-clearing immunity. Cytokine Growth Factor Rev. 19 (2008) 285-294
    • (2008) Cytokine Growth Factor Rev. , vol.19 , pp. 285-294
    • Yu, P.1    Fu, Y.X.2
  • 120
    • 15444377017 scopus 로고    scopus 로고
    • Intratumor depletion of CD4+ cells unmasks tumor immunogenicity leading to the rejection of late-stage tumors
    • Yu P., Lee Y., Liu W., Krausz T., Chong A., Schreiber H., and Fu Y.X. Intratumor depletion of CD4+ cells unmasks tumor immunogenicity leading to the rejection of late-stage tumors. J. Exp. Med. 201 (2005) 779-791
    • (2005) J. Exp. Med. , vol.201 , pp. 779-791
    • Yu, P.1    Lee, Y.2    Liu, W.3    Krausz, T.4    Chong, A.5    Schreiber, H.6    Fu, Y.X.7
  • 122
    • 51549090632 scopus 로고    scopus 로고
    • Expression of a soluble TGF-beta receptor by tumor cells enhances dendritic cell/tumor fusion vaccine efficacy
    • Zhang M., Berndt B.E., Chen J.J., and Kao J.Y. Expression of a soluble TGF-beta receptor by tumor cells enhances dendritic cell/tumor fusion vaccine efficacy. J. Immunol. 181 (2008) 3690-3697
    • (2008) J. Immunol. , vol.181 , pp. 3690-3697
    • Zhang, M.1    Berndt, B.E.2    Chen, J.J.3    Kao, J.Y.4
  • 123
    • 4043089873 scopus 로고    scopus 로고
    • The 4-1BB costimulation augments the proliferation of CD4+CD25+ regulatory T cells
    • Zheng G., Wang B., and Chen A. The 4-1BB costimulation augments the proliferation of CD4+CD25+ regulatory T cells. J. Immunol. 173 (2004) 2428-2434
    • (2004) J. Immunol. , vol.173 , pp. 2428-2434
    • Zheng, G.1    Wang, B.2    Chen, A.3
  • 125
    • 16844379997 scopus 로고    scopus 로고
    • Immunosuppressive networks in the tumour environment and their therapeutic relevance
    • Zou W. Immunosuppressive networks in the tumour environment and their therapeutic relevance. Nat. Rev. Cancer 5 (2005) 263-274
    • (2005) Nat. Rev. Cancer , vol.5 , pp. 263-274
    • Zou, W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.