Administration of either anti-CD40 or interleukin-12 following lethal total body irradiation induces acute lethal toxicity affecting the gut

Biology of Blood and Marrow Transplantation

Volumn 8, Issue 6, 2002, Pages 316-325

  Hixon, Julie A ^a   Anver, Miriam R ^a   Blazar, Bruce R ^a   Panoskaltsis Mortari, Angela ^a   Wiltrout, Robert H ^a   Murphy, William J ^a  

^a SAIC FREDERICK INC   (United States)

Author keywords

Antibodies; Cytokines; In vivo animal models; Transplantation

Indexed keywords

CD40 LIGAND MONOCLONAL ANTIBODY; CYTOKINE; FGK 45; GAMMA INTERFERON; INTERLEUKIN 12; INTERLEUKIN 2; PROTEIN P40; RECOMBINANT INTERLEUKIN 12; CD40 ANTIGEN; INTERLEUKIN 12P40; MONOCLONAL ANTIBODY; PROTEIN SUBUNIT;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; FEMALE; GASTROINTESTINAL TOXICITY; HISTOPATHOLOGY; IN VIVO STUDY; INTESTINE INJURY; KNOCKOUT MOUSE; LETHALITY; MALE; MORTALITY; MOUSE; NONHUMAN; WHOLE BODY RADIATION; ACUTE DISEASE; ANIMAL; BLOOD; CHEMICALLY INDUCED DISORDER; COMPARATIVE STUDY; ENTEROPATHY; GENETICS; IMMUNOLOGY; MOUSE MUTANT; MULTIMODALITY CANCER THERAPY; PHYSIOLOGY; SURVIVAL RATE;

ACUTE DISEASE; ANIMALS; ANTIBODIES, MONOCLONAL; ANTIGENS, CD40; COMBINED MODALITY THERAPY; FEMALE; INTERFERON TYPE II; INTERLEUKIN-12; INTERLEUKIN-12 SUBUNIT P40; INTESTINAL DISEASES; MICE; MICE, KNOCKOUT; PROTEIN SUBUNITS; SURVIVAL RATE; WHOLE-BODY IRRADIATION;

EID: 0036063949     PISSN: 10838791     EISSN: None     Source Type: Journal    
DOI: 10.1053/bbmt.2002.v8.pm12108917     Document Type: Article

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