Glutathione-dependent detoxification of α-oxoaldehydes by the glyoxalase system: Involvement in disease mechanisms and antiproliferative activity of glyoxalase I inhibitors

Chemico-Biological Interactions

Volumn 111-112, Issue , 1998, Pages 137-151

  Thornalley, Paul J ^a  

^a Glyoxalase Research Group   (United Kingdom)

Author keywords

Apoptosis; Cytokine; Disease mechanisms; Glycation; Glyoxalase; Therapeutic agents

Indexed keywords

ALPHA OXOALDEHYDE; AMINOGUANIDINE; CYTOKINE; ENZYME INHIBITOR; GLUTATHIONE; GLYOXAL; GLYOXALASE I INHIBITOR; HYDROXYACYLGLUTATHIONE HYDROLASE; LACTOYLGLUTATHIONE LYASE; METHYLGLYOXAL; UNCLASSIFIED DRUG;

APOPTOSIS; CANCER; CYTOTOXICITY; DETOXIFICATION; DIABETES MELLITUS; GLYCATION; HUMAN; NONHUMAN; OXIDATIVE STRESS; PATHOGENESIS; REVIEW;

MAMMALIA;

EID: 4244040278     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-2797(97)00157-9     Document Type: Article

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