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Volumn 277, Issue 4, 1997, Pages 325-332

Effects of acadesine on myocardial infarction, stroke, and death following surgery: A meta-analysis of the 5 international randomized trials

Author keywords

[No Author keywords available]

Indexed keywords

5 AMINO 4 IMIDAZOLECARBOXAMIDE; CARDIOPLEGIC AGENT; PURINE NUCLEOSIDE;

EID: 0031021506     PISSN: 00987484     EISSN: None     Source Type: Journal    
DOI: 10.1001/jama.277.4.325     Document Type: Review
Times cited : (147)

References (54)
  • 1
    • 0025133993 scopus 로고
    • Perioperative cardiac morbidity
    • Mangano DT. Perioperative cardiac morbidity. Anesthesiology. 1990;72:153-184.
    • (1990) Anesthesiology , vol.72 , pp. 153-184
    • Mangano, D.T.1
  • 2
    • 1842341350 scopus 로고
    • Mortality, part A
    • US Public Health Service. Mortality, part A. Vital Health Stat 2. 1985;2:10-17, 67-68, 100-101.
    • (1985) Vital Health Stat 2 , vol.2 , pp. 10-17
  • 3
    • 0023830911 scopus 로고
    • Report of the ad hoc committee on risk factors for coronary artery bypass surgery
    • Kouchoukos NT, Ebert PA, Grover FL, Lindesmith GG. Report of the ad hoc committee on risk factors for coronary artery bypass surgery. Ann Thorac Surg. 1988;45:348-349.
    • (1988) Ann Thorac Surg , vol.45 , pp. 348-349
    • Kouchoukos, N.T.1    Ebert, P.A.2    Grover, F.L.3    Lindesmith, G.G.4
  • 4
    • 0021326669 scopus 로고
    • Myocardial infarction and mortality in the Coronary Artery Surgery Study (CASS) randomized trial
    • CASS Principal Investigators and Their Associates. Myocardial infarction and mortality in the Coronary Artery Surgery Study (CASS) randomized trial. N Engl J Med. 1984;310:750-758.
    • (1984) N Engl J Med , vol.310 , pp. 750-758
  • 5
    • 0017749796 scopus 로고
    • Treatment of chronic stable angina: A preliminary report of survival data of the randomized Veterans Administration Cooperative Study
    • Murphy ML, Hultgren HN, Detre K, Thomsen J, Takaro T, for the Participants of the Veterans Administration Cooperative Study. Treatment of chronic stable angina: a preliminary report of survival data of the randomized Veterans Administration Cooperative Study. N Engl J Med. 1977; 297:621-627.
    • (1977) N Engl J Med , vol.297 , pp. 621-627
    • Murphy, M.L.1    Hultgren, H.N.2    Detre, K.3    Thomsen, J.4    Takaro, T.5
  • 6
    • 0022337307 scopus 로고
    • European coronary surgery study
    • Varnauskas E. European coronary surgery study. Z Kardiol. 1985;6:73-78.
    • (1985) Z Kardiol , vol.6 , pp. 73-78
    • Varnauskas, E.1
  • 7
    • 0028471657 scopus 로고
    • Perioperative cardiac morbidity: Epidemiology, costs, problems, and solutions
    • Mangano DT. Perioperative cardiac morbidity: epidemiology, costs, problems, and solutions. West J Med. 1994;161:87-89.
    • (1994) West J Med , vol.161 , pp. 87-89
    • Mangano, D.T.1
  • 8
    • 0027479727 scopus 로고
    • Myocardial stunning: An overview
    • Mangano DT. Myocardial stunning: an overview. J Cardiac Surg. 1993;8:204-213.
    • (1993) J Cardiac Surg , vol.8 , pp. 204-213
    • Mangano, D.T.1
  • 9
    • 0024454449 scopus 로고
    • Increased adenosine concentration in blood from ischemic myocardium by AICA riboside: Effects on flow, granulocytes, and injury
    • Gruber HE, Hoffer ME, McAllister DR, et al. Increased adenosine concentration in blood from ischemic myocardium by AICA riboside: effects on flow, granulocytes, and injury. Circulation. 1989; 80:1400-1411.
    • (1989) Circulation , vol.80 , pp. 1400-1411
    • Gruber, H.E.1    Hoffer, M.E.2    McAllister, D.R.3
  • 10
    • 85047676330 scopus 로고
    • The prototype adenosine regulating agent for reducing myocardial ischemic injury
    • Mullane K. The prototype adenosine regulating agent for reducing myocardial ischemic injury. Cardiovasc Res. 1993;27:43-47.
    • (1993) Cardiovasc Res , vol.27 , pp. 43-47
    • Mullane, K.1
  • 11
    • 0028223260 scopus 로고
    • Initial multicenter randomized controlled trial on the safety and efficacy of acadesine in patients undergoing CABG surgery
    • Leung JL, Stanley T, Mathew J, for the McSpi Research Group. Initial multicenter randomized controlled trial on the safety and efficacy of acadesine in patients undergoing CABG surgery. Anesth Analg. 1994;78:420-434.
    • (1994) Anesth Analg , vol.78 , pp. 420-434
    • Leung, J.L.1    Stanley, T.2    Mathew, J.3
  • 12
    • 0025642510 scopus 로고
    • Association of perioperative myocardial ischemia with cardiac morbidity and mortality in men undergoing noncardiac surgery
    • Mangano DT, Browner WS, Hollenberg M, London MJ, Tubau JF, Tateo IM, for the McSPI Research Group. Association of perioperative myocardial ischemia with cardiac morbidity and mortality in men undergoing noncardiac surgery. N Engl J Med. 1990;323:1781-1788.
    • (1990) N Engl J Med , vol.323 , pp. 1781-1788
    • Mangano, D.T.1    Browner, W.S.2    Hollenberg, M.3    London, M.J.4    Tubau, J.F.5    Tateo, I.M.6
  • 13
    • 0028862741 scopus 로고
    • Aeadesine: A new drug that may improve myocardial protection in coronary artery bypass graft surgery: results of the first international multicenter study
    • Menasché P, Jamieson WRE, Flameng E, Davies M, on behalf of the Multinational Aeadesine Study Group, Aeadesine: a new drug that may improve myocardial protection in coronary artery bypass graft surgery: results of the first international multicenter study. J Thorac Cardiovasc Surg. 1995;110:1096-1106.
    • (1995) J Thorac Cardiovasc Surg , vol.110 , pp. 1096-1106
    • Menasché, P.1    Jamieson, W.R.E.2    Flameng, E.3    Davies, M.4
  • 14
    • 0029133895 scopus 로고
    • Effects of acadesine on morbidity and mortality following coronary artery bypass graft surgery
    • The Multicenter Study of Perioperative Ischemia (McSPI) Research Group. Effects of acadesine on morbidity and mortality following coronary artery bypass graft surgery. Anesthesiology. 1995; 83:658-673.
    • (1995) Anesthesiology , vol.83 , pp. 658-673
  • 15
    • 24244440179 scopus 로고    scopus 로고
    • Effects of acadesine on myocardial infarction, stroke, and death following surgery
    • Mangano DT, for the McSPI Research Group. Effects of acadesine on myocardial infarction, stroke, and death following surgery. Anesth Analg. 1996; 82:SCA42.
    • (1996) Anesth Analg , vol.82
    • Mangano, D.T.1
  • 16
    • 0013555127 scopus 로고
    • Cardioprotective effects of acadesine in patients with unstable angina undergoing aortocoronary bypass surgery
    • Demeyere RH, Van Kerrebroeck CJ, Flameng WJ. Cardioprotective effects of acadesine in patients with unstable angina undergoing aortocoronary bypass surgery. Circulation. 1994;90(4, pt 2):I-370.
    • (1994) Circulation , vol.90 , Issue.4 PT 2
    • Demeyere, R.H.1    Van Kerrebroeck, C.J.2    Flameng, W.J.3
  • 17
    • 0029150226 scopus 로고
    • From science to practice: Meta-analyses using individual patient data are needed
    • Oxman AD, Clarke MJ, Stewart LA. From science to practice: meta-analyses using individual patient data are needed. JAMA. 1995;274:845-846.
    • (1995) JAMA , vol.274 , pp. 845-846
    • Oxman, A.D.1    Clarke, M.J.2    Stewart, L.A.3
  • 18
    • 0029097672 scopus 로고
    • A comparison of meta-analytic results using literature vs individual patient data: Paternal cell immunization for recurrent miscarriage
    • Jeng GT, Scott JR, Burmeister LF. A comparison of meta-analytic results using literature vs individual patient data: paternal cell immunization for recurrent miscarriage. JAMA. 1995;274:830-836.
    • (1995) JAMA , vol.274 , pp. 830-836
    • Jeng, G.T.1    Scott, J.R.2    Burmeister, L.F.3
  • 19
    • 0026009636 scopus 로고
    • A general parametric approach to the meta-analysis of randomized clinical trials
    • Whitehead A, Whitehead J. A general parametric approach to the meta-analysis of randomized clinical trials. Stat Med. 1991;10:1665-1677.
    • (1991) Stat Med , vol.10 , pp. 1665-1677
    • Whitehead, A.1    Whitehead, J.2
  • 20
    • 0021909115 scopus 로고
    • Beta blockade during and after myocardial infarction: An overview of the randomized trials
    • Yusuf S, Peto R, Lewis J, Collins R, Sleight P. Beta blockade during and after myocardial infarction: an overview of the randomized trials. Prog Cardiovasc Dis. 1985;27:335-371.
    • (1985) Prog Cardiovasc Dis , vol.27 , pp. 335-371
    • Yusuf, S.1    Peto, R.2    Lewis, J.3    Collins, R.4    Sleight, P.5
  • 24
    • 0028353851 scopus 로고
    • The chanuging clinical profile of coronary artery bypass graft patients, 1970-1989
    • Haraphongse M, Na-Ayudhya RK, Teo KK, et al. The chanuging clinical profile of coronary artery bypass graft patients, 1970-1989. Can J Cordial. 1994;10:71-86.
    • (1994) Can J Cordial , vol.10 , pp. 71-86
    • Haraphongse, M.1    Na-Ayudhya, R.K.2    Teo, K.K.3
  • 25
    • 0029841524 scopus 로고    scopus 로고
    • Calculating risk and outcome: The Society of Thoracic Surgeons database
    • Clark RE. Calculating risk and outcome: the Society of Thoracic Surgeons database. Ann Thorac Surg. 1996;62:S2-5.
    • (1996) Ann Thorac Surg , vol.62
    • Clark, R.E.1
  • 26
    • 0001480821 scopus 로고
    • Incidence of Q wave myocardial infarction during coronary artery bypass graft surgery in the 24-center McSPI population
    • Jain U, Zhang A, Sears RJ, Titov V, Titov T, for the McSPI Research Group. Incidence of Q wave myocardial infarction during coronary artery bypass graft surgery in the 24-center McSPI population. Anesthesiology. 1994;81:A157.
    • (1994) Anesthesiology , vol.81
    • Jain, U.1    Zhang, A.2    Sears, R.J.3    Titov, V.4    Titov, T.5
  • 27
    • 1842323120 scopus 로고
    • CK-MB release after coronary artery bypass graft surgery in a multicenter population
    • Aggarwal A, Jain U, Ramsay JG, Wilson R, Comunale ME, for the McSPI Research Group. CK-MB release after coronary artery bypass graft surgery in a multicenter population. Anesthesiology. 1994;81: A1291.
    • (1994) Anesthesiology , vol.81
    • Aggarwal, A.1    Jain, U.2    Ramsay, J.G.3    Wilson, R.4    Comunale, M.E.5
  • 29
    • 0028069748 scopus 로고
    • Randomised trial of normothermic versus hypothermic coronary bypass surgery
    • The Warm Heart Investigators. Randomised trial of normothermic versus hypothermic coronary bypass surgery. Lancet. 1994;343:559-563.
    • (1994) Lancet , vol.343 , pp. 559-563
  • 30
    • 0028195035 scopus 로고
    • Prospective, randomized trial of retrograde warm-blood cardioplegia: Myocardial benefit and neurologic threat
    • Martin TC, Craver JM, Gott JP, et al. Prospective, randomized trial of retrograde warm-blood cardioplegia: myocardial benefit and neurologic threat. Ann Thorac Surg. 1994;57:298-304.
    • (1994) Ann Thorac Surg , vol.57 , pp. 298-304
    • Martin, T.C.1    Craver, J.M.2    Gott, J.P.3
  • 31
    • 0028252559 scopus 로고
    • A prospective randomised study of continuous warm versus intermittent cold blood cardioplegia for coronary artery surgery: Preliminary report
    • Rashid A, Fabri BM, Fabri BM, et al. A prospective randomised study of continuous warm versus intermittent cold blood cardioplegia for coronary artery surgery: preliminary report. Eur J Cardiothorac Surg. 1994;8:265-269.
    • (1994) Eur J Cardiothorac Surg , vol.8 , pp. 265-269
    • Rashid, A.1    Fabri, B.M.2    Fabri, B.M.3
  • 32
    • 0026533883 scopus 로고
    • Protective effects of adenosine in myoeardial ischemia
    • Ely SW, Berne RM. Protective effects of adenosine in myoeardial ischemia. Circulation. 1992;85: 893-904.
    • (1992) Circulation , vol.85 , pp. 893-904
    • Ely, S.W.1    Berne, R.M.2
  • 33
    • 0027418487 scopus 로고
    • Acadesine: Prototype adenosine regulating agent for treating myocardial ischemia-reperfusion injury
    • Mullane K, Young M. Acadesine: prototype adenosine regulating agent for treating myocardial ischemia-reperfusion injury. Drug Des Res. 1993; 28:336-343.
    • (1993) Drug des Res , vol.28 , pp. 336-343
    • Mullane, K.1    Young, M.2
  • 34
    • 0024578837 scopus 로고
    • Effects of ATP precursors on ATP and free ADP content and functional recovery of postischemic hearts
    • Ambrosio G, Jacobus W, Mitehell M, Litt M, Becker L. Effects of ATP precursors on ATP and free ADP content and functional recovery of postischemic hearts. Am J Physiol. 1989;256:H560-H566.
    • (1989) Am J Physiol , vol.256
    • Ambrosio, G.1    Jacobus, W.2    Mitehell, M.3    Litt, M.4    Becker, L.5
  • 35
    • 0023930350 scopus 로고
    • The acute effects of AICAR on purine nueleotide metabolism and postischemic cardiac function
    • Mentzer R, Ely S, Lasley R, Berne R. The acute effects of AICAR on purine nueleotide metabolism and postischemic cardiac function. J Thorac Cardiovas Surg. 1988;95:286-293.
    • (1988) J Thorac Cardiovas Surg , vol.95 , pp. 286-293
    • Mentzer, R.1    Ely, S.2    Lasley, R.3    Berne, R.4
  • 36
    • 0027484011 scopus 로고
    • Acadesine improves surgical myocardial protection with blood cardioplegia in isehemically injured canine hearts
    • Vinten-Johansen J, Nakanishi K, Zhao ZQ, McGee DS, Tan P. Acadesine improves surgical myocardial protection with blood cardioplegia in isehemically injured canine hearts. Circulation. 1993; 88:350-358.
    • (1993) Circulation , vol.88 , pp. 350-358
    • Vinten-Johansen, J.1    Nakanishi, K.2    Zhao, Z.Q.3    McGee, D.S.4    Tan, P.5
  • 37
    • 0026668252 scopus 로고
    • Sustained protection by acadesine against ischemia and reperfusion-induced injury: Studies in the transplanted rat heart
    • Galiñanes M, Bullough D, Mullane KM, Hearse DJ. Sustained protection by acadesine against ischemia and reperfusion-induced injury: studies in the transplanted rat heart. Circulation. 1992;86:589-597.
    • (1992) Circulation , vol.86 , pp. 589-597
    • Galiñanes, M.1    Bullough, D.2    Mullane, K.M.3    Hearse, D.J.4
  • 38
    • 0017383508 scopus 로고
    • Sample size determination for rxc comparative trials
    • Lachin J. Sample size determination for rxc comparative trials. Biometrics. 1977;331:315-324.
    • (1977) Biometrics , vol.331 , pp. 315-324
    • Lachin, J.1
  • 39
    • 0026327664 scopus 로고
    • Progressive cardiac dysfunction with repeated pacing-induced ischemia: Protection by AICA-riboside
    • Young M, Mullane K. Progressive cardiac dysfunction with repeated pacing-induced ischemia: protection by AICA-riboside. Am J Physiol. 1991; 261:H1570-H1577.
    • (1991) Am J Physiol , vol.261
    • Young, M.1    Mullane, K.2
  • 40
    • 84969056216 scopus 로고
    • Acadesine preserves cardiac function and enhances coronary blood flow in isolated, blood perfused rabbit hearts with repeated ischemia and reperfusion
    • Mazur C, Mullane K, Young MA. Acadesine preserves cardiac function and enhances coronary blood flow in isolated, blood perfused rabbit hearts with repeated ischemia and reperfusion. J Mol Cell Cardiol. 1991;23:S45.
    • (1991) J Mol Cell Cardiol , vol.23
    • Mazur, C.1    Mullane, K.2    Young, M.A.3
  • 41
    • 1842352002 scopus 로고
    • AICA-riboside supresses arrhythmias induced by coronary artery occlusion and reperfusion
    • Molina-Viamonte V, Rosen MR. AICA-riboside supresses arrhythmias induced by coronary artery occlusion and reperfusion. Circulation. 1990;82:645.
    • (1990) Circulation , vol.82 , pp. 645
    • Molina-Viamonte, V.1    Rosen, M.R.2
  • 42
    • 84914935059 scopus 로고
    • Adenosine release from red cells mediates inhibition of platelet aggregation by acadesine and delays post-thrombolytic reoeelusion in dogs
    • Henry C, Young M, Zhang C, Bullough D, Muliane K. Adenosine release from red cells mediates inhibition of platelet aggregation by acadesine and delays post-thrombolytic reoeelusion in dogs. Circ Suppl. 1991;84:247.
    • (1991) Circ Suppl , vol.84 , pp. 247
    • Henry, C.1    Young, M.2    Zhang, C.3    Bullough, D.4    Muliane, K.5
  • 43
    • 1842348082 scopus 로고
    • Inhibition of intracoronary thrombosis by acadesine: An adenosine-mediated, erythrocyte-dependent activity
    • Young M, Montag A, Zhang C, Bullough D, Mullane K. Inhibition of intracoronary thrombosis by acadesine: an adenosine-mediated, erythrocyte-dependent activity. Eur Heart J. 1993;31:14.
    • (1993) Eur Heart J , vol.31 , pp. 14
    • Young, M.1    Montag, A.2    Zhang, C.3    Bullough, D.4    Mullane, K.5
  • 44
    • 0025967399 scopus 로고
    • Methotrexate inhibits neutrophil function by stimulating adenosine release from connective tissue cells
    • Cronstein BN, Eberle MA, Gruber HE, Levin RI. Methotrexate inhibits neutrophil function by stimulating adenosine release from connective tissue cells. Proc Natl Acad Sci U S A. 1991;88:2441-2445.
    • (1991) Proc Natl Acad Sci U S A , vol.88 , pp. 2441-2445
    • Cronstein, B.N.1    Eberle, M.A.2    Gruber, H.E.3    Levin, R.I.4
  • 45
    • 0026661329 scopus 로고
    • Acadesine and myocardial protection: Studies of time of administration and dose-response relations in the rat
    • Galiñanes M, Mullane KM, Bullough D, Hearse DJ. Acadesine and myocardial protection: studies of time of administration and dose-response relations in the rat. Circulation. 1992;86:598-608.
    • (1992) Circulation , vol.86 , pp. 598-608
    • Galiñanes, M.1    Mullane, K.M.2    Bullough, D.3    Hearse, D.J.4
  • 46
    • 0021012476 scopus 로고
    • Diagnostic criteria and prognosis of perioperative myocardial infarction following coronary bypass
    • Val PG, Pelletier LC, Hernandez MG, et al. Diagnostic criteria and prognosis of perioperative myocardial infarction following coronary bypass. J Thorac Cardiovasc Surg. 1983;86:878-886.
    • (1983) J Thorac Cardiovasc Surg , vol.86 , pp. 878-886
    • Val, P.G.1    Pelletier, L.C.2    Hernandez, M.G.3
  • 47
    • 0021591242 scopus 로고
    • Detrimental effect of perioperative myocardial infarction on late survival after coronary artery bypass: Report from the Coronary Artery Surgery Study (CASS)
    • Schaff HV, Gersh BJ, Fisher LD, et al. Detrimental effect of perioperative myocardial infarction on late survival after coronary artery bypass: report from the Coronary Artery Surgery Study (CASS). J Thorac Cardiovasc Surg. 1984;88:972-981.
    • (1984) J Thorac Cardiovasc Surg , vol.88 , pp. 972-981
    • Schaff, H.V.1    Gersh, B.J.2    Fisher, L.D.3
  • 48
    • 0023915984 scopus 로고
    • Meta-analysis: A quantitative approach to research integration
    • Thacker SB. Meta-analysis: a quantitative approach to research integration. JAMA. 1988;259: 1685-1689.
    • (1988) JAMA , vol.259 , pp. 1685-1689
    • Thacker, S.B.1
  • 51
    • 0028964587 scopus 로고
    • Misleading meta-analysis: Lessons from 'an effective, safe, simple' intervention that wasn't
    • Egger M, Smith GD. Misleading meta-analysis: lessons from 'an effective, safe, simple' intervention that wasn't. BMJ. 1995;310:752-754.
    • (1995) BMJ , vol.310 , pp. 752-754
    • Egger, M.1    Smith, G.D.2
  • 52
    • 0026652402 scopus 로고
    • A comparison of results of meta-analyses of randomized control trials and recommendations of clinical experts: Treatments for myocardial infarction
    • Antman EM, Lau J, Kupeinick B, Mosteller F, Chalmers TC. A comparison of results of meta-analyses of randomized control trials and recommendations of clinical experts: treatments for myocardial infarction. JAMA. 1992;268:240-248.
    • (1992) JAMA , vol.268 , pp. 240-248
    • Antman, E.M.1    Lau, J.2    Kupeinick, B.3    Mosteller, F.4    Chalmers, T.C.5
  • 53
    • 0023245353 scopus 로고
    • Reference bias in reports of drug trials
    • Gotzsche PC. Reference bias in reports of drug trials. BMJ. 1987;95:654-656.
    • (1987) BMJ , vol.95 , pp. 654-656
    • Gotzsche, P.C.1
  • 54
    • 0028958766 scopus 로고
    • Magnesium in acute myocardial infarction
    • Yusuf S, Flather M. Magnesium in acute myocardial infarction. BMJ. 1995;310:751-752.
    • (1995) BMJ , vol.310 , pp. 751-752
    • Yusuf, S.1    Flather, M.2


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