Molecular characterization of a purified 5-HT4 receptor: A structural basis for drug efficacy

Journal of Biological Chemistry

Volumn 280, Issue 21, 2005, Pages 20253-20260

  Banères, Jean Louis ^a,b   Mesnier, Danielle ^a   Martin, Aimée ^a   Joubert, Lara ^b   Dumuis, Aline ^b   Bockaert, Joel ^b  

^a CNRS   (France)

^b UNIV MONTPELLIER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CHEMICAL ACTIVATION; COMPOSITION; CONFORMATIONS; ESCHERICHIA COLI; FLUORESCENCE; PROTEINS; ULTRAVIOLET RADIATION;

CIRCULAR DICHROISM (CD); CONFORMATIONAL STATE; DRUG EFFICACY; FLUORESCENCE EMISSION;

DRUG PRODUCTS;

G PROTEIN COUPLED RECEPTOR; LEUKOTRIENE B4 RECEPTOR; SEROTONIN 4 RECEPTOR;

AGONIST; ARTICLE; CIRCULAR DICHROISM; DISULFIDE BOND; ESCHERICHIA COLI; FLUORESCENCE SPECTROSCOPY; GENE EXPRESSION SYSTEM; LIGAND BINDING; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; RECEPTOR INTRINSIC ACTIVITY; RECEPTOR UPREGULATION; SIGNAL TRANSDUCTION; SITE DIRECTED MUTAGENESIS; STEADY STATE; ULTRAVIOLET SPECTROPHOTOMETRY;

ANIMALS; BENZIMIDAZOLES; BICYCLO COMPOUNDS, HETEROCYCLIC; BINDING SITES; CIRCULAR DICHROISM; DRUG THERAPY; ESCHERICHIA COLI; GENE EXPRESSION; INDOLES; MICE; MUTAGENESIS, SITE-DIRECTED; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEIN STRUCTURE, SECONDARY; RECEPTORS, SEROTONIN, 5-HT4; RECOMBINANT PROTEINS; SEROTONIN ANTAGONISTS; SPECTROMETRY, FLUORESCENCE; STRUCTURE-ACTIVITY RELATIONSHIP; SULFONAMIDES;

ESCHERICHIA COLI;

EID: 20144385917     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M412009200     Document Type: Article

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