Diminished pancreatic β-cell mass in securin-null mice is caused by β-cell apoptosis and senescence

Endocrinology

Volumn 150, Issue 6, 2009, Pages 2603-2610

  Chesnokova, Vera ^a   Wong, Chris ^a   Zonis, Svetlana ^a   Gruszka, Anna ^a   Wawrowsky, Kolja ^a   Ren, Song Guang ^a   BenShlomo, Anat ^a   Yu, Run ^a,b  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b CEDARS SINAI MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; CYCLIN DEPENDENT KINASE INHIBITOR; MESSENGER RNA; PROTEIN P21; SECURIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CELL PROLIFERATION; CELL SIZE; CHROMOSOME ANALYSIS; CONTROLLED STUDY; DIABETES MELLITUS; DNA DAMAGE; FEMALE; GENE; GENE DELETION; HYPOINSULINEMIA; HYPOPLASIA; MALE; MOUSE; NONHUMAN; NULL ALLELE; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PTTG GENE; SENESCENCE;

ANIMALS; APOPTOSIS; BETA-GALACTOSIDASE; CARRIER PROTEINS; CELL AGING; CELL PROLIFERATION; CYCLIN-DEPENDENT KINASE INHIBITOR P21; DNA DAMAGE; FEMALE; GENE DELETION; INSULIN-SECRETING CELLS; MALE; MICE; MICE, TRANSGENIC;

EID: 66649104890     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2008-0972     Document Type: Article

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