-
1
-
-
23844549294
-
-
World Health Organization , Geneva
-
World Health Organization (2005) The World Malaria report 2005. Geneva.
-
(2005)
The World Malaria report 2005
-
-
-
2
-
-
0037020035
-
Malaria control with genetically manipulated insect vectors
-
Alphey L, Beard CB, Billingsley P, Coetzee M, Crisanti A, et al. (2002) Malaria control with genetically manipulated insect vectors. Science 298: 119-121.
-
(2002)
Science
, vol.298
, pp. 119-121
-
-
Alphey, L.1
Beard, C.B.2
Billingsley, P.3
Coetzee, M.4
Crisanti, A.5
-
3
-
-
34347385078
-
Malaria vector control in the third millennium: Progress and perspectives of molecular approaches
-
Catteruccia F (2007) Malaria vector control in the third millennium: progress and perspectives of molecular approaches. Pest Manag Sci 63: 634-640.
-
(2007)
Pest Manag Sci
, vol.63
, pp. 634-640
-
-
Catteruccia, F.1
-
4
-
-
0032510796
-
The mosquito Anopheles stephensi limits malaria parasite development with inducible synthesis of nitric oxide
-
Luckhart S, Vodovotz Y, Cui L, Rosenberg R (1998) The mosquito Anopheles stephensi limits malaria parasite development with inducible synthesis of nitric oxide. Proc Natl Acad Sci U S A 95: 5700-5705.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 5700-5705
-
-
Luckhart, S.1
Vodovotz, Y.2
Cui, L.3
Rosenberg, R.4
-
5
-
-
0037020201
-
Immunity-related genes and gene families in Anopheles gambiae
-
Christophides GK, Zdobnov E, Barillas-Mury C, Birney E, Blandin S, et al.(2002) Immunity-related genes and gene families in Anopheles gambiae. Science 298: 159-165.
-
(2002)
Science
, vol.298
, pp. 159-165
-
-
Christophides, G.K.1
Zdobnov, E.2
Barillas-Mury, C.3
Birney, E.4
Blandin, S.5
-
6
-
-
0037240250
-
Insect immunity and its implication in mosquito-malaria interactions
-
Dimopoulos G (2003) Insect immunity and its implication in mosquito-malaria interactions. Cell Microbiol 5: 3-14.
-
(2003)
Cell Microbiol
, vol.5
, pp. 3-14
-
-
Dimopoulos, G.1
-
7
-
-
33751508853
-
Nitric oxide metabolites induced in Anopheles stephensi control malaria parasite infection
-
Peterson TM, Gow AJ, Luckhart S (2007) Nitric oxide metabolites induced in Anopheles stephensi control malaria parasite infection. Free Radic Biol Med 42: 132-142.
-
(2007)
Free Radic Biol Med
, vol.42
, pp. 132-142
-
-
Peterson, T.M.1
Gow, A.J.2
Luckhart, S.3
-
8
-
-
44649094083
-
-
Mendes AM, Schlegelmilch T, Cohuet A, Awono-Ambene P, De Iorio M, et al. (2008) Conserved mosquito/parasite interactions affect development of Plasmodium falciparum in Africa. PLoS Pathog 4: e1000069. doi:10.1371/journal. ppat.1000069.
-
Mendes AM, Schlegelmilch T, Cohuet A, Awono-Ambene P, De Iorio M, et al. (2008) Conserved mosquito/parasite interactions affect development of Plasmodium falciparum in Africa. PLoS Pathog 4: e1000069. doi:10.1371/journal. ppat.1000069.
-
-
-
-
9
-
-
1642301073
-
Effects of mosquito genes on Plasmodium development
-
Osta MA, Christophides GK, Kafatos FC (2004) Effects of mosquito genes on Plasmodium development. Science 303: 2030-2032.
-
(2004)
Science
, vol.303
, pp. 2030-2032
-
-
Osta, M.A.1
Christophides, G.K.2
Kafatos, F.C.3
-
10
-
-
33749533649
-
Boosting NF-kappaB-dependent basal immunity of Anopheles gambiae aborts development of Plasmodium berghei
-
Frolet C, Thoma M, Blandin S, Hoffmann JA, Levashina EA (2006) Boosting NF-kappaB-dependent basal immunity of Anopheles gambiae aborts development of Plasmodium berghei. Immunity 25: 677-685.
-
(2006)
Immunity
, vol.25
, pp. 677-685
-
-
Frolet, C.1
Thoma, M.2
Blandin, S.3
Hoffmann, J.A.4
Levashina, E.A.5
-
11
-
-
23844521954
-
Immune signaling pathways regulating bacterial and malaria parasite infection of the mosquito Anopheles gambiae
-
Meister S, Kanzok SM, Zheng XL, Luna C, Li TR, et al. (2005) Immune signaling pathways regulating bacterial and malaria parasite infection of the mosquito Anopheles gambiae. Proc Natl Acad Sci U S A 102: 11420-11425.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 11420-11425
-
-
Meister, S.1
Kanzok, S.M.2
Zheng, X.L.3
Luna, C.4
Li, T.R.5
-
12
-
-
40049086593
-
Transgenic mosquitoes and the fight against malaria: Managing technology push in a turbulent GMO world
-
Knols BG, Bossin HC, Mukabana WR, Robinson AS (2007) Transgenic mosquitoes and the fight against malaria: managing technology push in a turbulent GMO world. Am J Trop Med Hyg 77: 232-242.
-
(2007)
Am J Trop Med Hyg
, vol.77
, pp. 232-242
-
-
Knols, B.G.1
Bossin, H.C.2
Mukabana, W.R.3
Robinson, A.S.4
-
13
-
-
0038104944
-
Mammalian transforming growth factor beta1 activated after ingestion by Anopheles stephensi modulates mosquito immunity
-
Luckhart S, Crampton AL, Zamora R, Lieber MJ, Dos Santos PC, et al. (2003) Mammalian transforming growth factor beta1 activated after ingestion by Anopheles stephensi modulates mosquito immunity. Infect Immun 71: 3000-3009.
-
(2003)
Infect Immun
, vol.71
, pp. 3000-3009
-
-
Luckhart, S.1
Crampton, A.L.2
Zamora, R.3
Lieber, M.J.4
Dos Santos, P.C.5
-
14
-
-
37449010330
-
Low levels of mammalian TGF-beta1 are protective against malaria parasite infection, a paradox clarified in the mosquito host
-
Luckhart S, Lieber MJ, Singh N, Zamora R, Vodovotz Y (2008) Low levels of mammalian TGF-beta1 are protective against malaria parasite infection, a paradox clarified in the mosquito host. Exp Parasitol 118: 290-296.
-
(2008)
Exp Parasitol
, vol.118
, pp. 290-296
-
-
Luckhart, S.1
Lieber, M.J.2
Singh, N.3
Zamora, R.4
Vodovotz, Y.5
-
15
-
-
4043166192
-
Transforming growth factor-betas and related gene products in mosquito vectors of human malaria parasites: Signaling architecture for immunological crosstalk
-
Lieber MJ, Luckhart S (2004) Transforming growth factor-betas and related gene products in mosquito vectors of human malaria parasites: signaling architecture for immunological crosstalk. Mol Immunol 41: 965-977.
-
(2004)
Mol Immunol
, vol.41
, pp. 965-977
-
-
Lieber, M.J.1
Luckhart, S.2
-
16
-
-
0036888335
-
Integration of the TGF-beta pathway into the cellular signalling network
-
Lutz M, Knaus P (2002) Integration of the TGF-beta pathway into the cellular signalling network. Cell Signal 14: 977-988.
-
(2002)
Cell Signal
, vol.14
, pp. 977-988
-
-
Lutz, M.1
Knaus, P.2
-
17
-
-
33846086980
-
Transforming growth factor-beta: Innately bipolar
-
Wahl SM (2007) Transforming growth factor-beta: innately bipolar. Curr Opin Immunol 19: 55-62.
-
(2007)
Curr Opin Immunol
, vol.19
, pp. 55-62
-
-
Wahl, S.M.1
-
18
-
-
0033953639
-
Maintaining the immunological balance in parasitic infections: A role for TGF-beta?
-
Omer FM, Kurtzhals JA, Riley EM (2000) Maintaining the immunological balance in parasitic infections: a role for TGF-beta? Parasitol Today 16: 18-23.
-
(2000)
Parasitol Today
, vol.16
, pp. 18-23
-
-
Omer, F.M.1
Kurtzhals, J.A.2
Riley, E.M.3
-
19
-
-
36448936383
-
TGFbeta-SMAD signal transduction: Molecular specificity and functional flexibility
-
Schmierer B, Hill CS (2007) TGFbeta-SMAD signal transduction: molecular specificity and functional flexibility. Nat Rev Mol Cell Biol 8: 970-982.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 970-982
-
-
Schmierer, B.1
Hill, C.S.2
-
20
-
-
0038682002
-
Mechanisms of TGF-beta signaling from cell membrane to the nucleus
-
Shi Y, Massague J (2003) Mechanisms of TGF-beta signaling from cell membrane to the nucleus. Cell 113: 685-700.
-
(2003)
Cell
, vol.113
, pp. 685-700
-
-
Shi, Y.1
Massague, J.2
-
21
-
-
24944497786
-
Non-Smad TGF-beta signals
-
Moustakas A, Heldin CH (2005) Non-Smad TGF-beta signals. J Cell Sci 118: 3573-3584.
-
(2005)
J Cell Sci
, vol.118
, pp. 3573-3584
-
-
Moustakas, A.1
Heldin, C.H.2
-
22
-
-
0034023127
-
Role of Ras and Mapks in TGFbeta signaling
-
Mulder KM (2000) Role of Ras and Mapks in TGFbeta signaling. Cytokine Growth Factor Rev 11: 23-35.
-
(2000)
Cytokine Growth Factor Rev
, vol.11
, pp. 23-35
-
-
Mulder, K.M.1
-
23
-
-
0033580393
-
Cross-talk between the Smad1 and Ras/ MEK signaling pathways for TGFbeta
-
Yue J, Frey RS, Mulder KM (1999) Cross-talk between the Smad1 and Ras/ MEK signaling pathways for TGFbeta. Oncogene 18: 2033-2037.
-
(1999)
Oncogene
, vol.18
, pp. 2033-2037
-
-
Yue, J.1
Frey, R.S.2
Mulder, K.M.3
-
24
-
-
33750354369
-
Disruption of JNK2 decreases the cytokine response to Plasmodium falciparum glycosylphosphatidylinositol in vitro and confers protection in a cerebral malaria model
-
Lu Z, Serghides L, Patel SN, Degousee N, Rubin BB, et al. (2006) Disruption of JNK2 decreases the cytokine response to Plasmodium falciparum glycosylphosphatidylinositol in vitro and confers protection in a cerebral malaria model. J Immunol 177: 6344-6352.
-
(2006)
J Immunol
, vol.177
, pp. 6344-6352
-
-
Lu, Z.1
Serghides, L.2
Patel, S.N.3
Degousee, N.4
Rubin, B.B.5
-
25
-
-
33947263045
-
Disruption of CD36 impairs cytokine response to Plasmodium falciparum glycosylphosphatidylinositol and confers susceptibility to severe and fatal malaria in vivo
-
Patel SN, Lu Z, Ayi K, Serghides L, Gowda DC, et al. (2007) Disruption of CD36 impairs cytokine response to Plasmodium falciparum glycosylphosphatidylinositol and confers susceptibility to severe and fatal malaria in vivo. J Immunol 178: 3954-3961.
-
(2007)
J Immunol
, vol.178
, pp. 3954-3961
-
-
Patel, S.N.1
Lu, Z.2
Ayi, K.3
Serghides, L.4
Gowda, D.C.5
-
26
-
-
14844304290
-
Induction of proinflammatory responses in macrophages by the glycosylphosphatidylinositols of Plasmodium falciparum: The requirement of extracellular signal-regulated kinase, p38, c-Jun Nterminal kinase and NF-kappaB pathways for the expression of proinflammatory cytokines and nitric oxide
-
Zhu J, Krishnegowda G, Gowda DC (2005) Induction of proinflammatory responses in macrophages by the glycosylphosphatidylinositols of Plasmodium falciparum: the requirement of extracellular signal-regulated kinase, p38, c-Jun Nterminal kinase and NF-kappaB pathways for the expression of proinflammatory cytokines and nitric oxide. J Biol Chem 280: 8617-8627.
-
(2005)
J Biol Chem
, vol.280
, pp. 8617-8627
-
-
Zhu, J.1
Krishnegowda, G.2
Gowda, D.C.3
-
27
-
-
24644476507
-
Crosstalk mechanisms between the mitogenactivated protein kinase pathways and Smad signaling downstream of TGF-beta: Implications for carcinogenesis
-
Javelaud D, Mauviel A (2005) Crosstalk mechanisms between the mitogenactivated protein kinase pathways and Smad signaling downstream of TGF-beta: implications for carcinogenesis. Oncogene 24: 5742-5750.
-
(2005)
Oncogene
, vol.24
, pp. 5742-5750
-
-
Javelaud, D.1
Mauviel, A.2
-
28
-
-
0029788015
-
Altered transforming growth factor signaling in epithelial cells when ras activation is blocked
-
Hartsough MT, Frey RS, Zipfel PA, Buard A, Cook SJ, et al. (1996) Altered transforming growth factor signaling in epithelial cells when ras activation is blocked. J Biol Chem 271: 22368-22375.
-
(1996)
J Biol Chem
, vol.271
, pp. 22368-22375
-
-
Hartsough, M.T.1
Frey, R.S.2
Zipfel, P.A.3
Buard, A.4
Cook, S.J.5
-
29
-
-
0030751329
-
Transforming growth factor-beta signaling in epithelial cells
-
Hartsough MT, Mulder KM (1997) Transforming growth factor-beta signaling in epithelial cells. Pharmacol Ther 75: 21-41.
-
(1997)
Pharmacol Ther
, vol.75
, pp. 21-41
-
-
Hartsough, M.T.1
Mulder, K.M.2
-
31
-
-
2542508922
-
A hemocyte-like cell line established from the malaria vector Anopheles gambiae expresses six prophenoloxidase genes
-
Muller HM, Dimopoulos G, Blass C, Kafatos FC (1999) A hemocyte-like cell line established from the malaria vector Anopheles gambiae expresses six prophenoloxidase genes. J Biol Chem 274: 11727-11735.
-
(1999)
J Biol Chem
, vol.274
, pp. 11727-11735
-
-
Muller, H.M.1
Dimopoulos, G.2
Blass, C.3
Kafatos, F.C.4
-
32
-
-
42149146781
-
Insulin regulates aging and oxidative stress in Anopheles stephensi
-
Kang MA, Mott TM, Tapley EC, Lewis EE, Luckhart S (2008) Insulin regulates aging and oxidative stress in Anopheles stephensi. J Exp Biol 211: 741-748.
-
(2008)
J Exp Biol
, vol.211
, pp. 741-748
-
-
Kang, M.A.1
Mott, T.M.2
Tapley, E.C.3
Lewis, E.E.4
Luckhart, S.5
-
33
-
-
17644428078
-
Induction of nitric oxide synthase in Anopheles stephensi by Plasmodium falciparum: Mechanism of signaling and the role of parasite glycosylphosphatidylinositols
-
Lim J, Gowda DC, Krishnegowda G, Luckhart S (2005) Induction of nitric oxide synthase in Anopheles stephensi by Plasmodium falciparum: mechanism of signaling and the role of parasite glycosylphosphatidylinositols. Infect Immun 73: 2778-2789.
-
(2005)
Infect Immun
, vol.73
, pp. 2778-2789
-
-
Lim, J.1
Gowda, D.C.2
Krishnegowda, G.3
Luckhart, S.4
-
34
-
-
38049144182
-
Regulation of p53 tetramerization and nuclear export by ARC
-
Foo RS, Nam YJ, Ostreicher MJ, Metzl MD, Whelan RS, et al. (2007) Regulation of p53 tetramerization and nuclear export by ARC. Proc Natl Acad Sci U S A 104: 20826-20831.
-
(2007)
Proc Natl Acad Sci U S A
, vol.104
, pp. 20826-20831
-
-
Foo, R.S.1
Nam, Y.J.2
Ostreicher, M.J.3
Metzl, M.D.4
Whelan, R.S.5
-
35
-
-
34249876564
-
Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells
-
Masui S, Nakatake Y, Toyooka Y, Shimosato D, Yagi R, et al. (2007) Pluripotency governed by Sox2 via regulation of Oct3/4 expression in mouse embryonic stem cells. Nat Cell Biol 9: 625-635.
-
(2007)
Nat Cell Biol
, vol.9
, pp. 625-635
-
-
Masui, S.1
Nakatake, Y.2
Toyooka, Y.3
Shimosato, D.4
Yagi, R.5
-
37
-
-
34249283723
-
Synthesis and evaluation of sulfonylurea derivatives as novel antimalarials
-
Leon C, Rodrigues J, Gamboa de Dominguez N, Charris J, Gut J, et al. (2007) Synthesis and evaluation of sulfonylurea derivatives as novel antimalarials. Eur J Med Chem 42: 735-742.
-
(2007)
Eur J Med Chem
, vol.42
, pp. 735-742
-
-
Leon, C.1
Rodrigues, J.2
Gamboa de Dominguez, N.3
Charris, J.4
Gut, J.5
-
38
-
-
0028950547
-
Decreased serum levels of TGF-beta in patients with acute Plasmodium falciparum malaria
-
Wenisch C, Parschalk B, Burgmann H, Looareesuwan S, Graninger W (1995) Decreased serum levels of TGF-beta in patients with acute Plasmodium falciparum malaria. J Clin Immunol 15: 69-73.
-
(1995)
J Clin Immunol
, vol.15
, pp. 69-73
-
-
Wenisch, C.1
Parschalk, B.2
Burgmann, H.3
Looareesuwan, S.4
Graninger, W.5
-
39
-
-
0033823645
-
Reduced interleukin-12 and transforming growth factor-beta1 in severe childhood malaria: Relationship of cytokine balance with disease severity
-
Perkins DJ, Weinberg JB, Kremsner PG (2000) Reduced interleukin-12 and transforming growth factor-beta1 in severe childhood malaria: relationship of cytokine balance with disease severity. J Infect Dis 182: 988-992.
-
(2000)
J Infect Dis
, vol.182
, pp. 988-992
-
-
Perkins, D.J.1
Weinberg, J.B.2
Kremsner, P.G.3
-
40
-
-
1642565101
-
Reduced levels of transforming growth factor-beta1, interleukin-12 and increased migration inhibitory factor are associated with severe malaria
-
Chaiyaroj SC, Rutta AS, Muenthaisong K, Watkins P, Na Ubol M, et al. (2004) Reduced levels of transforming growth factor-beta1, interleukin-12 and increased migration inhibitory factor are associated with severe malaria. Acta Trop 89: 319-327.
-
(2004)
Acta Trop
, vol.89
, pp. 319-327
-
-
Chaiyaroj, S.C.1
Rutta, A.S.2
Muenthaisong, K.3
Watkins, P.4
Na Ubol, M.5
-
41
-
-
33746128777
-
Clusters of cytokines determine malaria severity in Plasmodium falciparum-infected patients from endemic areas of Central India
-
Prakash D, Fesel C, Jain R, Cazenave PA, Mishra GC, et al. (2006) Clusters of cytokines determine malaria severity in Plasmodium falciparum-infected patients from endemic areas of Central India. J Infect Dis 194: 198-207.
-
(2006)
J Infect Dis
, vol.194
, pp. 198-207
-
-
Prakash, D.1
Fesel, C.2
Jain, R.3
Cazenave, P.A.4
Mishra, G.C.5
-
42
-
-
85176688244
-
-
Alessi DR, Cuenda A, Cohen P, Dudley DT, Saltiel AR (1995) PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J Biol Chem 270: 27489-27494.
-
Alessi DR, Cuenda A, Cohen P, Dudley DT, Saltiel AR (1995) PD 098059 is a specific inhibitor of the activation of mitogen-activated protein kinase kinase in vitro and in vivo. J Biol Chem 270: 27489-27494.
-
-
-
-
43
-
-
14444279192
-
Identification of a novel inhibitor of mitogen-activated protein kinase kinase
-
Favata MF, Horiuchi KY, Manos EJ, Daulerio AJ, Stradley DA, et al. (1998) Identification of a novel inhibitor of mitogen-activated protein kinase kinase. J Biol Chem 273: 18623-18632.
-
(1998)
J Biol Chem
, vol.273
, pp. 18623-18632
-
-
Favata, M.F.1
Horiuchi, K.Y.2
Manos, E.J.3
Daulerio, A.J.4
Stradley, D.A.5
-
44
-
-
0031726220
-
Metabolic changes of the malaria parasite during the transition from the human to the mosquito host
-
Lang-Unnasch N, Murphy AD (1998) Metabolic changes of the malaria parasite during the transition from the human to the mosquito host. Annu Rev Microbiol 52: 561-590.
-
(1998)
Annu Rev Microbiol
, vol.52
, pp. 561-590
-
-
Lang-Unnasch, N.1
Murphy, A.D.2
-
45
-
-
4644359359
-
Regulation of the expression of inducible nitric oxide synthase
-
Kleinert H, Pautz A, Linker K, Schwarz PM (2004) Regulation of the expression of inducible nitric oxide synthase. Eur J Pharmacol 500: 255-266.
-
(2004)
Eur J Pharmacol
, vol.500
, pp. 255-266
-
-
Kleinert, H.1
Pautz, A.2
Linker, K.3
Schwarz, P.M.4
-
46
-
-
5644293442
-
Cross-talk between nitric oxide and transforming growth factor-beta1 in malaria
-
Vodovotz Y, Zamora R, Lieber MJ, Luckhart S (2004) Cross-talk between nitric oxide and transforming growth factor-beta1 in malaria. Curr Mol Med 4: 787-797.
-
(2004)
Curr Mol Med
, vol.4
, pp. 787-797
-
-
Vodovotz, Y.1
Zamora, R.2
Lieber, M.J.3
Luckhart, S.4
-
47
-
-
0037319834
-
Characterization of JNK-like protein derived from a mosquito cell line, C6/36
-
Mizutani T, Kobayashi M, Eshita Y, Inanami O, Yamamori T, et al. (2003)Characterization of JNK-like protein derived from a mosquito cell line, C6/36. Insect Mol Biol 12: 61-66.
-
(2003)
Insect Mol Biol
, vol.12
, pp. 61-66
-
-
Mizutani, T.1
Kobayashi, M.2
Eshita, Y.3
Inanami, O.4
Yamamori, T.5
-
48
-
-
34447618286
-
A p38 MAP kinase regulates the expression of the Aedes aegypti defensin gene in mosquito cells
-
Chen-Chih Wu R, Shaio MF, Cho WL (2007) A p38 MAP kinase regulates the expression of the Aedes aegypti defensin gene in mosquito cells. Insect Mol Biol 16: 389-399.
-
(2007)
Insect Mol Biol
, vol.16
, pp. 389-399
-
-
Chen-Chih Wu, R.1
Shaio, M.F.2
Cho, W.L.3
-
49
-
-
47649116758
-
Plasmodium development in the mosquito: Biology bottlenecks and opportunities for mathematical modeling
-
Drexler AL, Vodovotz Y, Luckhart S (2008) Plasmodium development in the mosquito: biology bottlenecks and opportunities for mathematical modeling. Trends Parasitol 24: 333-336.
-
(2008)
Trends Parasitol
, vol.24
, pp. 333-336
-
-
Drexler, A.L.1
Vodovotz, Y.2
Luckhart, S.3
-
50
-
-
37849012314
-
Progression of Plasmodium berghei through Anopheles stephensi is density-dependent
-
doi: 10.1371/journal.ppat.0030195
-
Sinden RE, Dawes EJ, Alavi Y, Waldock J, Finney O, et al. (2007) Progression of Plasmodium berghei through Anopheles stephensi is density-dependent. PLoS Pathog 3: e195. doi: 10.1371/journal.ppat.0030195.
-
(2007)
PLoS Pathog
, vol.3
-
-
Sinden, R.E.1
Dawes, E.J.2
Alavi, Y.3
Waldock, J.4
Finney, O.5
-
51
-
-
62749196220
-
Recent Developments in Anti-Cancer Agents Targeting the Ras/Raf/MEK/ERK Pathway
-
Wong KK (2009) Recent Developments in Anti-Cancer Agents Targeting the Ras/Raf/MEK/ERK Pathway. Recent Patents Anticancer Drug Discov 4: 28-35.
-
(2009)
Recent Patents Anticancer Drug Discov
, vol.4
, pp. 28-35
-
-
Wong, K.K.1
-
52
-
-
12344303646
-
PfPK7, an atypical MEK-related protein kinase, reflects the absence of classical threecomponent MAPK pathways in the human malaria parasite Plasmodium falciparum
-
Dorin D, Semblat JP, Poullet P, Alano P, Goldring JP, et al. (2005) PfPK7, an atypical MEK-related protein kinase, reflects the absence of classical threecomponent MAPK pathways in the human malaria parasite Plasmodium falciparum. Mol Microbiol 55: 184-196.
-
(2005)
Mol Microbiol
, vol.55
, pp. 184-196
-
-
Dorin, D.1
Semblat, J.P.2
Poullet, P.3
Alano, P.4
Goldring, J.P.5
-
53
-
-
9144258616
-
Protein kinases of the human malaria parasite Plasmodium falciparum: The kinome of a divergent eukaryote
-
Ward P, Equinet L, Packer J, Doerig C (2004) Protein kinases of the human malaria parasite Plasmodium falciparum: the kinome of a divergent eukaryote. BMC Genomics 5: 79.
-
(2004)
BMC Genomics
, vol.5
, pp. 79
-
-
Ward, P.1
Equinet, L.2
Packer, J.3
Doerig, C.4
-
54
-
-
0034330847
-
Nonopsonic monocyte/macrophage phagocytosis of Plasmodium falciparum- parasitized erythrocytes: A role for CD36 in malarial clearance
-
McGilvray ID, Serghides L, Kapus A, Rotstein OD, Kain KC (2000) Nonopsonic monocyte/macrophage phagocytosis of Plasmodium falciparum- parasitized erythrocytes: a role for CD36 in malarial clearance. Blood 96: 3231-3240.
-
(2000)
Blood
, vol.96
, pp. 3231-3240
-
-
McGilvray, I.D.1
Serghides, L.2
Kapus, A.3
Rotstein, O.D.4
Kain, K.C.5
-
55
-
-
46949091999
-
Plasmodium falciparum-free merozoites and infected RBCs distinctly affect soluble CD40 ligand-mediated maturation of immature monocyte-derived dendritic cells
-
Mukherjee P, Chauhan VS (2008) Plasmodium falciparum-free merozoites and infected RBCs distinctly affect soluble CD40 ligand-mediated maturation of immature monocyte-derived dendritic cells. J Leukoc Biol 84: 244-254.
-
(2008)
J Leukoc Biol
, vol.84
, pp. 244-254
-
-
Mukherjee, P.1
Chauhan, V.S.2
-
56
-
-
43049175154
-
TGF-beta1 targets the GSK-3beta/beta-catenin pathway via ERK activation in the transition of human lung fibroblasts into myofibroblasts
-
Caraci F, Gili E, Calafiore M, Failla M, La Rosa C, et al. (2008) TGF-beta1 targets the GSK-3beta/beta-catenin pathway via ERK activation in the transition of human lung fibroblasts into myofibroblasts. Pharmacol Res 57: 274-282.
-
(2008)
Pharmacol Res
, vol.57
, pp. 274-282
-
-
Caraci, F.1
Gili, E.2
Calafiore, M.3
Failla, M.4
La Rosa, C.5
-
57
-
-
32644470779
-
MAPK/AP-1- dependent regulation of PAI-1 gene expression by TGF-beta in rat mesangial cells
-
Guo B, Inoki K, Isono M, Mori H, Kanasaki K, et al. (2005) MAPK/AP-1- dependent regulation of PAI-1 gene expression by TGF-beta in rat mesangial cells. Kidney Int 68: 972-984.
-
(2005)
Kidney Int
, vol.68
, pp. 972-984
-
-
Guo, B.1
Inoki, K.2
Isono, M.3
Mori, H.4
Kanasaki, K.5
-
58
-
-
34247590285
-
TGF-beta 1 inhibition of IFN-gammainduced signaling and Th1 gene expression in CD4+ T cells is Smad3 independent but MAP kinase dependent
-
Park IK, Letterio JJ, Gorham JD (2007) TGF-beta 1 inhibition of IFN-gammainduced signaling and Th1 gene expression in CD4+ T cells is Smad3 independent but MAP kinase dependent. Mol Immunol 44: 3283-3290.
-
(2007)
Mol Immunol
, vol.44
, pp. 3283-3290
-
-
Park, I.K.1
Letterio, J.J.2
Gorham, J.D.3
-
59
-
-
0142104985
-
Smad-dependent and Smad-independent pathways in TGF-beta family signalling
-
Derynck R, Zhang YE (2003) Smad-dependent and Smad-independent pathways in TGF-beta family signalling. Nature 425: 577-584.
-
(2003)
Nature
, vol.425
, pp. 577-584
-
-
Derynck, R.1
Zhang, Y.E.2
-
60
-
-
0035823510
-
Cross-talk between the p42/p44 MAP kinase and Smad pathways in transforming growth factor beta 1-induced furin gene transactivation
-
Blanchette F, Rivard N, Rudd P, Grondin F, Attisano L, et al. (2001) Cross-talk between the p42/p44 MAP kinase and Smad pathways in transforming growth factor beta 1-induced furin gene transactivation. J Biol Chem 276: 33986-33994.
-
(2001)
J Biol Chem
, vol.276
, pp. 33986-33994
-
-
Blanchette, F.1
Rivard, N.2
Rudd, P.3
Grondin, F.4
Attisano, L.5
-
61
-
-
0033106484
-
A mechanism of repression of TGFbeta/Smad signaling by oncogenic Ras
-
Kretzschmar M, Doody J, Timokhina I, Massague J (1999) A mechanism of repression of TGFbeta/Smad signaling by oncogenic Ras. Genes Dev 13: 804-816.
-
(1999)
Genes Dev
, vol.13
, pp. 804-816
-
-
Kretzschmar, M.1
Doody, J.2
Timokhina, I.3
Massague, J.4
-
62
-
-
2442489944
-
Transforming growth factor-beta 1 regulation of collagenase-3 expression in osteoblastic cells by cross-talk between the Smad and MAPK signaling pathways and their components, Smad2 and Runx2
-
Selvamurugan N, Kwok S, Alliston T, Reiss M, Partridge NC (2004) Transforming growth factor-beta 1 regulation of collagenase-3 expression in osteoblastic cells by cross-talk between the Smad and MAPK signaling pathways and their components, Smad2 and Runx2. J Biol Chem 279: 19327-19334.
-
(2004)
J Biol Chem
, vol.279
, pp. 19327-19334
-
-
Selvamurugan, N.1
Kwok, S.2
Alliston, T.3
Reiss, M.4
Partridge, N.C.5
-
63
-
-
36148968456
-
RAS/ERK modulates TGFbeta-regulated PTEN expression in human pancreatic adenocarcinoma cells
-
Chow JY, Quach KT, Cabrera BL, Cabral JA, Beck SE, et al. (2007) RAS/ERK modulates TGFbeta-regulated PTEN expression in human pancreatic adenocarcinoma cells. Carcinogenesis 28: 2321-2327.
-
(2007)
Carcinogenesis
, vol.28
, pp. 2321-2327
-
-
Chow, J.Y.1
Quach, K.T.2
Cabrera, B.L.3
Cabral, J.A.4
Beck, S.E.5
-
64
-
-
32944477055
-
Extracellular signalregulated kinase 1/2 mitogen-activated protein kinase pathway is involved in myostatin-regulated differentiation repression
-
Yang W, Chen Y, Zhang Y, Wang X, Yang N, et al. (2006) Extracellular signalregulated kinase 1/2 mitogen-activated protein kinase pathway is involved in myostatin-regulated differentiation repression. Cancer Res 66: 1320-1326.
-
(2006)
Cancer Res
, vol.66
, pp. 1320-1326
-
-
Yang, W.1
Chen, Y.2
Zhang, Y.3
Wang, X.4
Yang, N.5
-
65
-
-
0030773834
-
Opposing BMP and EGF signalling pathways converge on the TGF-beta family mediator Smad1
-
Kretzschmar M, Doody J, Massague J (1997) Opposing BMP and EGF signalling pathways converge on the TGF-beta family mediator Smad1. Nature 389: 618-622.
-
(1997)
Nature
, vol.389
, pp. 618-622
-
-
Kretzschmar, M.1
Doody, J.2
Massague, J.3
-
66
-
-
34250860090
-
Drosophila Nemo antagonizes BMP signaling by phosphorylation of Mad and inhibition of its nuclear accumulation
-
Zeng YA, Rahnama M, Wang S, Sosu-Sedzorme W, Verheyen EM (2007) Drosophila Nemo antagonizes BMP signaling by phosphorylation of Mad and inhibition of its nuclear accumulation. Development 134: 2061-2071.
-
(2007)
Development
, vol.134
, pp. 2061-2071
-
-
Zeng, Y.A.1
Rahnama, M.2
Wang, S.3
Sosu-Sedzorme, W.4
Verheyen, E.M.5
-
67
-
-
0141923698
-
Hemozoin increases IFN-gamma-inducible macrophage nitric oxide generation through extracellular signal-regulated kinase- and NF-kappa B-dependent pathways
-
Jaramillo M, Gowda DC, Radzioch D, Olivier M (2003) Hemozoin increases IFN-gamma-inducible macrophage nitric oxide generation through extracellular signal-regulated kinase- and NF-kappa B-dependent pathways. J Immunol 171: 4243-4253.
-
(2003)
J Immunol
, vol.171
, pp. 4243-4253
-
-
Jaramillo, M.1
Gowda, D.C.2
Radzioch, D.3
Olivier, M.4
-
68
-
-
34547618476
-
Induction of nitric oxide synthase and activation of signaling proteins in Anopheles mosquitoes by the malaria pigment, hemozoin
-
Akman-Anderson L, Olivier M, Luckhart S (2007) Induction of nitric oxide synthase and activation of signaling proteins in Anopheles mosquitoes by the malaria pigment, hemozoin. Infect Immun 75: 4012-4019.
-
(2007)
Infect Immun
, vol.75
, pp. 4012-4019
-
-
Akman-Anderson, L.1
Olivier, M.2
Luckhart, S.3
-
69
-
-
34547177916
-
The integration of signaling by multiprotein complexes containing Raf kinases
-
Kyriakis JM (2007) The integration of signaling by multiprotein complexes containing Raf kinases. Biochim Biophys Acta 1773: 1238-1247.
-
(2007)
Biochim Biophys Acta
, vol.1773
, pp. 1238-1247
-
-
Kyriakis, J.M.1
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