TGF-β1 targets the GSK-3β/β-catenin pathway via ERK activation in the transition of human lung fibroblasts into myofibroblasts

Pharmacological Research

Volumn 57, Issue 4, 2008, Pages 274-282

  Caraci, Filippo ^a   Gili, Elisa ^a   Calafiore, Marco ^a   Failla, Marco ^a   La Rosa, Cristina ^a   Crimi, Nunzio ^a   Sortino, Maria Angela ^a   Nicoletti, Ferdinando ^b,c   Copani, Agata ^a,d   Vancheri, Carlo ^a  

^a UNIVERSITY OF CATANIA   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c IRCCS NEUROMED   (Italy)

^d CNR   (Italy)

Author keywords

SMA; Catenin; ERK1 2; Fibroblast; GSK 3 ; TGF 1

Indexed keywords

2 (2 AMINO 3 METHOXYPHENYL)CHROMONE; ALPHA SMOOTH MUSCLE ACTIN; BETA CATENIN; COLLAGEN; GLYCOGEN SYNTHASE KINASE 3BETA; LITHIUM CHLORIDE; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; SMALL INTERFERING RNA; TRANSFORMING GROWTH FACTOR BETA1; ACTIN; ALPHA SMA PROTEIN, HUMAN; ALPHA-SMA PROTEIN, HUMAN; GLYCOGEN SYNTHASE KINASE 3; GLYCOGEN SYNTHASE KINASE 3 BETA; MITOGEN ACTIVATED PROTEIN KINASE;

ADULT; ARTICLE; CELL TRANSFORMATION; COLLAGEN SYNTHESIS; CONFOCAL MICROSCOPY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; HUMAN; HUMAN CELL; LUNG FIBROBLAST; MOLECULAR DYNAMICS; MOUSE; MYOFIBROBLAST; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN TARGETING; PROTEIN TRANSPORT; RNA INTERFERENCE; WESTERN BLOTTING; ACTIVE TRANSPORT; BIOSYNTHESIS; CELL LINE; CELL NUCLEUS; CYTOLOGY; DRUG ANTAGONISM; DRUG EFFECT; FIBROBLAST; METABOLISM;

ACTINS; ACTIVE TRANSPORT, CELL NUCLEUS; BETA CATENIN; CELL LINE; CELL NUCLEUS; COLLAGEN; ENZYME ACTIVATION; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FIBROBLASTS; GLYCOGEN SYNTHASE KINASE 3; HUMANS; TRANSFORMING GROWTH FACTOR BETA1;

EID: 43049175154     PISSN: 10436618     EISSN: 10961186     Source Type: Journal    
DOI: 10.1016/j.phrs.2008.02.001     Document Type: Article

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