TGF-β1 inhibition of IFN-γ-induced signaling and Th1 gene expression in CD4+ T cells is Smad3 independent but MAP kinase dependent

Molecular Immunology

Volumn 44, Issue 13, 2007, Pages 3283-3290

  Park, Il Kyoo ^a   Letterio, John J ^b   Gorham, James D ^a  

^a DARTMOUTH MEDICAL SCHOOL   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

IFN ; T helper cell; TGF ; Th1

Indexed keywords

GAMMA INTERFERON; INTERFERON; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE 2; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4; MITOGEN ACTIVATED PROTEIN KINASE P38; SMAD3 PROTEIN; TRANSFORMING GROWTH FACTOR BETA1;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INHIBITION; GENE EXPRESSION; INHIBITION KINETICS; LYMPHOCYTE FUNCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; SIGNAL PROCESSING; SIGNAL TRANSDUCTION; TH1 CELL;

ANIMALS; CELLS, CULTURED; GENE EXPRESSION REGULATION; INTERFERON TYPE II; MAP KINASE SIGNALING SYSTEM; MICE; MICE, INBRED BALB C; MICE, KNOCKOUT; MITOGEN-ACTIVATED PROTEIN KINASES; SMAD3 PROTEIN; TH1 CELLS; TRANSFORMING GROWTH FACTOR BETA1;

EID: 34247590285     PISSN: 01615890     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.molimm.2007.02.024     Document Type: Article

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