메뉴 건너뛰기




Volumn 53, Issue 5, 2009, Pages 600-608

Phytochemicals in olive-leaf extracts and their antiproliferative activity against cancer and endothelial cells

Author keywords

Angiogenesis; Cancer; LC SPE NMR; Oleuropein; Olive leaf extract

Indexed keywords

ANTINEOPLASTIC AGENT; ANTIOXIDANT; PLANT EXTRACT;

EID: 66149158379     PISSN: 16134125     EISSN: 16134133     Source Type: Journal    
DOI: 10.1002/mnfr.200800204     Document Type: Article
Times cited : (185)

References (54)
  • 1
    • 0038310626 scopus 로고    scopus 로고
    • Adherence to a Mediterranean diet and survival in a Greek population
    • Trichopoulou, A., Costacou, T., Bamia, C., Trichopoulos, D., Adherence to a Mediterranean diet and survival in a Greek population, N. Engl. J. Med. 2003, 348, 2599-2608.
    • (2003) N. Engl. J. Med. , vol.348 , pp. 2599-2608
    • Trichopoulou, A.1    Costacou, T.2    Bamia, C.3    Trichopoulos, D.4
  • 2
    • 4544368258 scopus 로고    scopus 로고
    • Mediterranean diet, lifestyle factors, and 10- year mortality in Elderly European men and women: The HALE project
    • Knoops, K. T. B., de Groot, L. C. P. G. M., Kromhout, D., Perrin, A.-E., et al., Mediterranean diet, lifestyle factors, and 10- year mortality in Elderly European men and women: The HALE project, JAMA 2004, 292, 1433-1439.
    • (2004) JAMA , vol.292 , pp. 1433-1439
    • Knoops, K.T.B.1    de Groot, L.C.P.G.M.2    Kromhout, D.3    Perrin, A.-E.4
  • 3
    • 4544288392 scopus 로고    scopus 로고
    • Effect of a Mediterranean-style diet on endothelial dysfunction and markers of vascular nnflammation in the metabolic syndrome: A randomized trial
    • Esposito, K., Marfella, R., Ciotola, M., Di Palo, C., et al., Effect of a Mediterranean-style diet on endothelial dysfunction and markers of vascular nnflammation in the metabolic syndrome: A randomized trial, JAMA 2004, 292, 1440-1446.
    • (2004) JAMA , vol.292 , pp. 1440-1446
    • Esposito, K.1    Marfella, R.2    Ciotola, M.3    Di Palo, C.4
  • 4
    • 35548946627 scopus 로고    scopus 로고
    • Nutrition in the genomics era: Cardiovascular disease risk and the Mediterra-nean diet
    • Ordovas, J. M., Kaput, J., Corella, D., Nutrition in the genomics era: Cardiovascular disease risk and the Mediterra-nean diet, Mol. Nutr. Food Res. 2007, 51, 1293-1299.
    • (2007) Mol. Nutr. Food Res. , vol.51 , pp. 1293-1299
    • Ordovas, J.M.1    Kaput, J.2    Corella, D.3
  • 5
    • 35548952213 scopus 로고    scopus 로고
    • Intervention studies on Mediterranean diet and cardiovascular risk
    • Lairon, D., Intervention studies on Mediterranean diet and cardiovascular risk, Mol. Nutr. Food Res. 2007, 51, 1209-1214.
    • (2007) Mol. Nutr. Food Res. , vol.51 , pp. 1209-1214
    • Lairon, D.1
  • 6
    • 20044376670 scopus 로고    scopus 로고
    • Hydroxytyrosol, a natural antioxidant from olive oil, prevents protein damage induced by long-wave ultraviolet radiation in melanoma cells
    • D'Angelo, S., Ingrosso, D., Migliardi, V., Sorrentino, A., et al., Hydroxytyrosol, a natural antioxidant from olive oil, prevents protein damage induced by long-wave ultraviolet radiation in melanoma cells, Free Radic. Biol. Med. 2005, 38, 908-919.
    • (2005) Free Radic. Biol. Med. , vol.38 , pp. 908-919
    • D'Angelo, S.1    Ingrosso, D.2    Migliardi, V.3    Sorrentino, A.4
  • 7
    • 33845705480 scopus 로고    scopus 로고
    • Dietary polyphenolic phytochemicals - Promising cancer chemopreventive agents in humans? A review of their clinical properties
    • Thomasset, S. C., Berry, D. P., Garcea, G., Marczylo, T., et al., Dietary polyphenolic phytochemicals - Promising cancer chemopreventive agents in humans? A review of their clinical properties, Int. J. Cancer 2007, 120, 451-458.
    • (2007) Int.J. Cancer , vol.120 , pp. 451-458
    • Thomasset, S.C.1    Berry, D.P.2    Garcea, G.3    Marczylo, T.4
  • 8
    • 27744511607 scopus 로고    scopus 로고
    • Use of cancer chemopreventive phytochemicals as antineoplastic agents
    • D' Incalci, M., Steward, W. P., Gescher, A. J., Use of cancer chemopreventive phytochemicals as antineoplastic agents, Lancet Oncol. 2005, 6, 899-904.
    • (2005) Lancet Oncol. , vol.6 , pp. 899-904
    • D' Incalci, M.1    Steward, W.P.2    Gescher, A.J.3
  • 9
    • 34447283477 scopus 로고    scopus 로고
    • Ins and outs of dietary phytochemicals in cancer chemoprevention
    • Russo, G. L., Ins and outs of dietary phytochemicals in cancer chemoprevention, Biochem. Pharmacol. 2007, 74, 533-544.
    • (2007) Biochem. Pharmacol. , vol.74 , pp. 533-544
    • Russo, G.L.1
  • 10
    • 0142166328 scopus 로고    scopus 로고
    • Cancer chemoprevention with dietary phyto-chemicals
    • Surh, Y.-J., Cancer chemoprevention with dietary phyto-chemicals, Nat. Rev. Cancer 2003, 3, 768-780.
    • (2003) Nat. Rev. Cancer , vol.3 , pp. 768-780
    • Surh, Y.-J.1
  • 12
    • 34247109045 scopus 로고    scopus 로고
    • Natural products as sources of new drugs over the last 25 years
    • Newman, D. J., Cragg, G. M., Natural products as sources of new drugs over the last 25 years, J. Nat. Prod. 2007, 70, 461-477.
    • (2007) J. Nat. Prod. , vol.70 , pp. 461-477
    • Newman, D.J.1    Cragg, G.M.2
  • 13
    • 23044490704 scopus 로고    scopus 로고
    • Plants as a source of anti-cancer agents
    • Cragg, G. M., Newman, D. J., Plants as a source of anti-cancer agents, J. Ethnopharmacol. 2005, 100, 72-79.
    • (2005) J. Ethnopharmacol. , vol.100 , pp. 72-79
    • Cragg, G.M.1    Newman, D.J.2
  • 14
    • 33646067755 scopus 로고    scopus 로고
    • Natural product extracts of plant and marine origin having antileukemia potential. The NCI experience
    • Cragg, G. M., Newman, D. J., Yang, S. S., Natural product extracts of plant and marine origin having antileukemia potential. The NCI experience, J. Nat. Prod. 2006, 69, 488-498.
    • (2006) J.Nat. Prod. , vol.69 , pp. 488-498
    • Cragg, G.M.1    Newman, D.J.2    Yang, S.S.3
  • 15
    • 0242439376 scopus 로고    scopus 로고
    • Antioxidant effect of phenolic compounds, a-tocopherol, and other minor components in virgin olive oil
    • Mateos, R., Dominguez, M. M., Espartero, J. L., Cert, A., Antioxidant effect of phenolic compounds, a-tocopherol, and other minor components in virgin olive oil, J. Agric. Food Chem. 2003, 51, 7170-7175.
    • (2003) J. Agric. Food Chem. , vol.51 , pp. 7170-7175
    • Mateos, R.1    Dominguez, M.M.2    Espartero, J.L.3    Cert, A.4
  • 16
    • 23044525042 scopus 로고    scopus 로고
    • Mediterranean diet health benefits may be due to a synergistic combination of phytochemicals and fatty-acids
    • Fortes, C., Mediterranean diet health benefits may be due to a synergistic combination of phytochemicals and fatty-acids, BMJ (Clin. Res. Ed.) 2005, 331, E366.
    • (2005) BMJ (Clin. Res. Ed.) , vol.331
    • Fortes, C.1
  • 17
    • 33846161577 scopus 로고    scopus 로고
    • Presence of virgin olive oil phenolic metabolites in human low density lipoprotein fraction: Determination by high-performance liquid chromatography-electrospray ionization tandem mass spectrometry
    • de la Torre-Carbot, K., Chavez-Servin, J. L., Jauregui, O., Castellote, A. I., et al., Presence of virgin olive oil phenolic metabolites in human low density lipoprotein fraction: Determination by high-performance liquid chromatography-electrospray ionization tandem mass spectrometry, Anal. Chim Acta 2007, 583, 402-410.
    • (2007) Anal. Chim Acta , vol.583 , pp. 402-410
    • de la Torre-Carbot, K.1    Chavez-Servin, J.L.2    Jauregui, O.3    Castellote, A.I.4
  • 19
    • 35549009314 scopus 로고    scopus 로고
    • Molecular mechanisms of the effects of olive oil and other dietary lipids on cancer
    • Escrich, E., Moral, R., Grau, L., Costa, I., et. al. Molecular mechanisms of the effects of olive oil and other dietary lipids on cancer, Mol. Nutr. Food Res. 2007, 51, 1279-1292.
    • (2007) Mol. Nutr. Food Res. , vol.51 , pp. 1279-1292
    • Escrich, E.1    Moral, R.2    Grau, L.3    Costa, I.4
  • 20
    • 0037077381 scopus 로고    scopus 로고
    • Olea europaea L. leaf extract and derivatives: Antioxidant properties
    • Briante, R., Patumi, M., Terenziani, S., Bismuto, E., et al., Olea europaea L. leaf extract and derivatives: Antioxidant properties. J. Agric. Food Chem. 2002, 50, 4934-4940.
    • (2002) J. Agric. Food Chem. , vol.50 , pp. 4934-4940
    • Briante, R.1    Patumi, M.2    Terenziani, S.3    Bismuto, E.4
  • 21
    • 13244295506 scopus 로고    scopus 로고
    • Analysis and quantification of flavonoidic compounds from Portuguese olive (olea europaea L.) leaf cultivars
    • Meirinhos, J., Silva, B. M., Valentao, P., Seabra, R. M., et al., Analysis and quantification of flavonoidic compounds from Portuguese olive (olea europaea L.) leaf cultivars, Nat. Prod. Res. 2005, 19, 189-195.
    • (2005) Nat.Prod. Res. , vol.19 , pp. 189-195
    • Meirinhos, J.1    Silva, B.M.2    Valentao, P.3    Seabra, R.M.4
  • 22
    • 0028075792 scopus 로고
    • Oleuropein protects low density lipoprotein from oxidation
    • Visioli, F., Galli, C., Oleuropein protects low density lipoprotein from oxidation, Life Sci. 1994, 55, 1965-1971.
    • (1994) Life Sci. , vol.55 , pp. 1965-1971
    • Visioli, F.1    Galli, C.2
  • 23
    • 34247133519 scopus 로고    scopus 로고
    • Trends in complementary/alternative medicine use by breast cancer survivors: Comparing survey data from 1998 and 2005
    • Boon, H. S., Olatunde, F., Zick, S. M., Trends in complementary/alternative medicine use by breast cancer survivors: Comparing survey data from 1998 and 2005, BMC Womens Health 2007, 7, 4.
    • (2007) BMC Womens Health , vol.7 , pp. 4
    • Boon, H.S.1    Olatunde, F.2    Zick, S.M.3
  • 24
    • 33947505554 scopus 로고    scopus 로고
    • Complementary and alternative medicine among advanced cancer patients enrolled on phase I trials: A study of prognosis, quality of life, and preferences for decision making
    • Hlubocky, F. J., Ratain, M. J., Wen, M., Daugherty, C. K., Complementary and alternative medicine among advanced cancer patients enrolled on phase I trials: A study of prognosis, quality of life, and preferences for decision making, J. Clin. Oncol. 2007, 25, 548-554.
    • (2007) J. Clin. Oncol. , vol.25 , pp. 548-554
    • Hlubocky, F.J.1    Ratain, M.J.2    Wen, M.3    Daugherty, C.K.4
  • 25
    • 34249863300 scopus 로고    scopus 로고
    • Olive oil's bitter principle reverses acquired autore-sistance to trastuzumab (Herceptin™) in HER2-overexpressing breast cancer cells
    • Menendez, J. A., Vazquez-Martin, A., Colomer, R., Brunet, J., et al., Olive oil's bitter principle reverses acquired autore-sistance to trastuzumab (Herceptin™) in HER2-overexpressing breast cancer cells, BMC Cancer 2007, 7, 80.
    • (2007) BMC Cancer , vol.7 , pp. 80
    • Menendez, J.A.1    Vazquez-Martin, A.2    Colomer, R.3    Brunet, J.4
  • 26
    • 33846844941 scopus 로고    scopus 로고
    • Discovery of small-molecule HIV-1 fusion and integrase inhibitors oleuropein and hydroxytyrosol: Part I. Integrase inhibition
    • Lee-Huang, S., Huang, P. L., Zhang, D., Lee, J. W., et al., Discovery of small-molecule HIV-1 fusion and integrase inhibitors oleuropein and hydroxytyrosol: Part I. Integrase inhibition, Biochem. Biophys. Res. Commun. 2007, 354, 872-878.
    • (2007) Biochem. Biophys. Res. Commun. , vol.354 , pp. 872-878
    • Lee-Huang, S.1    Huang, P.L.2    Zhang, D.3    Lee, J.W.4
  • 27
    • 33846821864 scopus 로고    scopus 로고
    • Discovery of small-molecule HIV-1 fusion and integrase inhibitors oleuropein and hydroxytyrosol: Part II. Integrase inhibition
    • Lee-Huang, S., Huang, P. L., Zhang, D., Lee, J. W., et al., Discovery of small-molecule HIV-1 fusion and integrase inhibitors oleuropein and hydroxytyrosol: Part II. Integrase inhibition, Biochem. Biophys. Res. Commun. 2007, 354, 879-884.
    • (2007) Biochem. Biophys. Res. Commun. , vol.354 , pp. 879-884
    • Lee-Huang, S.1    Huang, P.L.2    Zhang, D.3    Lee, J.W.4
  • 28
    • 22744447495 scopus 로고    scopus 로고
    • Oleuropein, a nontoxic olive iri-doid, is an anti-tumor agent and cytoskeleton disruptor
    • Hamdi, H. K., Castellon, R., Oleuropein, a nontoxic olive iri-doid, is an anti-tumor agent and cytoskeleton disruptor, Bio-chem. Biophys. Res. Commun. 2005, 334, 769-778.
    • (2005) Bio-chem. Biophys. Res. Commun. , vol.334 , pp. 769-778
    • Hamdi, H.K.1    Castellon, R.2
  • 29
    • 34347407870 scopus 로고    scopus 로고
    • Induction of growth inhibition and differentiation of human leukemia HL-60 cells by a Tunisian gerboui olive leaf extract
    • Abaza, L., Talorete, T. P. N., Yamada, P., Kurita, Y., et al., Induction of growth inhibition and differentiation of human leukemia HL-60 cells by a Tunisian gerboui olive leaf extract, Biosci. Biotechnol. Biochem. 2007, 71, 1306-1312.
    • (2007) Biosci. Biotechnol. Biochem. , vol.71 , pp. 1306-1312
    • Abaza, L.1    Talorete, T.P.N.2    Yamada, P.3    Kurita, Y.4
  • 30
    • 0032830879 scopus 로고    scopus 로고
    • Liquid chromatography with electrospray ionisation mass spectro-metric detection of phenolic compounds from Olea europaea
    • Ryan, D., Robards, K., Prenzler, P., Jardine, D., et al., Liquid chromatography with electrospray ionisation mass spectro-metric detection of phenolic compounds from Olea europaea, J. Chromatogr. A 1999, 855, 529-537.
    • (1999) J. Chromatogr. A , vol.855 , pp. 529-537
    • Ryan, D.1    Robards, K.2    Prenzler, P.3    Jardine, D.4
  • 31
    • 0037462015 scopus 로고    scopus 로고
    • Quantitative changes in phenolic content during physiological development of the olive (Olea europaea) cultivar Hardy's Mammoth
    • Ryan, D., Prenzler, P. D., Lavee, S., Antolovich, M., et al., Quantitative changes in phenolic content during physiological development of the olive (Olea europaea) cultivar Hardy's Mammoth, J. Agric. Food Chem. 2003, 51, 2532-2538.
    • (2003) J.Agric. Food Chem. , vol.51 , pp. 2532-2538
    • Ryan, D.1    Prenzler, P.D.2    Lavee, S.3    Antolovich, M.4
  • 32
    • 33644512420 scopus 로고    scopus 로고
    • Factors affecting the contents of iridoid oleuropein in olive leaves (Olea europaea L.)
    • Ranalli, A., Contento, S., Lucera, L., Di Febo, M., et al., Factors affecting the contents of iridoid oleuropein in olive leaves (Olea europaea L.), J. Agric. Food Chem. 2006, 54, 434-440.
    • (2006) J.Agric. Food Chem. , vol.54 , pp. 434-440
    • Ranalli, A.1    Contento, S.2    Lucera, L.3    Di Febo, M.4
  • 33
    • 33847641037 scopus 로고    scopus 로고
    • Hydroxytyrosol lipophilic analogues: Enzymatic synthesis, radical scavenging activity and DNA oxidative damage protection
    • Grasso, S., Siracusa, L., Spatafora, C., Renis, M., et al., Hydroxytyrosol lipophilic analogues: Enzymatic synthesis, radical scavenging activity and DNA oxidative damage protection, Bioorg. Chem. 2007, 35, 137-152.
    • (2007) Bioorg. Chem. , vol.35 , pp. 137-152
    • Grasso, S.1    Siracusa, L.2    Spatafora, C.3    Renis, M.4
  • 34
    • 0036892587 scopus 로고    scopus 로고
    • Antioxidant activity and free radical scavenging capacity between Korean medicinal plants and flavonoids by assay-guided comparison
    • Choi, C. W., Kim, S. C., Hwang, S. S., Choi, B. K., et al., Antioxidant activity and free radical scavenging capacity between Korean medicinal plants and flavonoids by assay-guided comparison, Plant Sci. 2002, 163, 1161-1168.
    • (2002) Plant Sci. , vol.163 , pp. 1161-1168
    • Choi, C.W.1    Kim, S.C.2    Hwang, S.S.3    Choi, B.K.4
  • 35
    • 0028895694 scopus 로고
    • Genistein, a dietary ingested isoflavonoid, inhibits cell proliferation and in vitro angiogenesis
    • Fotsis, T., Pepper, M., Adlercreutz, H., Hase, T., et al., Genistein, a dietary ingested isoflavonoid, inhibits cell proliferation and in vitro angiogenesis, J. Nutr. 1995, 125, 790S-795S.
    • (1995) J. Nutr. , vol.125
    • Fotsis, T.1    Pepper, M.2    Adlercreutz, H.3    Hase, T.4
  • 36
    • 0033178888 scopus 로고    scopus 로고
    • Down-regulation of endothelial cell growth inhibitors by enhanced MYCN oncogene expression in human neuroblastoma cells
    • Fotsis, T., Breit, S., Lutz, W., Rössler, J., et al., Down-regulation of endothelial cell growth inhibitors by enhanced MYCN oncogene expression in human neuroblastoma cells, Eur. J. Biochem. 1999, 263, 757-764.
    • (1999) Eur. J. Biochem. , vol.263 , pp. 757-764
    • Fotsis, T.1    Breit, S.2    Lutz, W.3    Rössler, J.4
  • 37
    • 0033945291 scopus 로고    scopus 로고
    • Phenolic compounds and squalene in olive oils: The concentration and antioxidant potential of total phenols, simple phenols, secoiridoids, lignans and squalene
    • Owen, R. W., Mier, W., Giacosa, A., Hull, W. E., et al., Phenolic compounds and squalene in olive oils: The concentration and antioxidant potential of total phenols, simple phenols, secoiridoids, lignans and squalene, Food Chem. Toxicol. 2000, 38, 647-659.
    • (2000) Food Chem. Toxicol. , vol.38 , pp. 647-659
    • Owen, R.W.1    Mier, W.2    Giacosa, A.3    Hull, W.E.4
  • 38
    • 0033859612 scopus 로고    scopus 로고
    • Flavonoids as antioxidants
    • Pietta, P.-G., Flavonoids as antioxidants, J. Nat. Prod. 2000, 63, 1035-1042.
    • (2000) J. Nat. Prod. , vol.63 , pp. 1035-1042
    • Pietta, P.-G.1
  • 39
    • 0036136289 scopus 로고    scopus 로고
    • Antioxidant and other biological activities of phenols from olives and olive oil
    • Visioli, F., Poli, A., Gall, C., Antioxidant and other biological activities of phenols from olives and olive oil, Med. Res. Rev. 2002, 22, 65-75.
    • (2002) Med. Res. Rev. , vol.22 , pp. 65-75
    • Visioli, F.1    Poli, A.2    Gall, C.3
  • 40
    • 20444411476 scopus 로고    scopus 로고
    • Linking solubility and permeability assays for maximum throughput and reproducibility
    • Wexler, D. S., Gao, L., Anderson, F., Ow, A., et al., Linking solubility and permeability assays for maximum throughput and reproducibility, J. Biomol. Screen. 2005, 10, 383-390.
    • (2005) J. Biomol. Screen. , vol.10 , pp. 383-390
    • Wexler, D.S.1    Gao, L.2    Anderson, F.3    Ow, A.4
  • 41
    • 0028340366 scopus 로고
    • Estimation and correlation of drug water solubility with pharma-cological parameters required for biological activity
    • Morelock, M. M., Choi, L. L., Bell, G. L., Wright, J. L., Estimation and correlation of drug water solubility with pharma-cological parameters required for biological activity, J. Pharm. Sci. 1994, 83, 948-952.
    • (1994) J. Pharm. Sci. , vol.83 , pp. 948-952
    • Morelock, M.M.1    Choi, L.L.2    Bell, G.L.3    Wright, J.L.4
  • 42
    • 33644847101 scopus 로고    scopus 로고
    • Virgin olive oil phenols inhibit proliferation of human promyelocytic leukemia cells (HL60) by inducing apoptosis and differentiation
    • Fabiani, R., De Bartolomeo, A., Rosignoli, P., Servili, M., et al., Virgin olive oil phenols inhibit proliferation of human promyelocytic leukemia cells (HL60) by inducing apoptosis and differentiation, J. Nutr. 2006, 136, 614-619.
    • (2006) J.Nutr. , vol.136 , pp. 614-619
    • Fabiani, R.1    De Bartolomeo, A.2    Rosignoli, P.3    Servili, M.4
  • 43
    • 34247898924 scopus 로고    scopus 로고
    • Caspase activation and extracellular signal-regulated kinase/Akt inhibition were involved in luteolin-induced apoptosis in Lewis lung carcinoma cells
    • Kim, J. H., Lee, E. O., Lee, H. J., Ku, J. S., et al., Caspase activation and extracellular signal-regulated kinase/Akt inhibition were involved in luteolin-induced apoptosis in Lewis lung carcinoma cells, Ann. NY Acad. Sci. 2007, 1095, 598-611.
    • (2007) Ann. NY Acad. Sci. , vol.1095 , pp. 598-611
    • Kim, J.H.1    Lee, E.O.2    Lee, H.J.3    Ku, J.S.4
  • 44
    • 7444272077 scopus 로고    scopus 로고
    • Luteolin inhibits vascular endothelial growth factor-induced angiogenesis; inhibition of endothelial cell survival and pro-liferation by targeting phosphatidylinositol 39-kinase activity
    • Bagli, E., Stefaniotou, M., Morbidelli, L., Ziche, M., et al., Luteolin inhibits vascular endothelial growth factor-induced angiogenesis; inhibition of endothelial cell survival and pro-liferation by targeting phosphatidylinositol 39-kinase activity, Cancer Res. 2004, 64, 7936-7946.
    • (2004) Cancer Res. , vol.64 , pp. 7936-7946
    • Bagli, E.1    Stefaniotou, M.2    Morbidelli, L.3    Ziche, M.4
  • 45
    • 23644451183 scopus 로고    scopus 로고
    • LC-NMR coupling technology: Recent advancements and applications in natural products analysis
    • Exarchou, V., Krucker, M., Van Beek, T. A., Vervoort, J., et al., LC-NMR coupling technology: Recent advancements and applications in natural products analysis, Magn. Reson. Chem. 2005, 43, 681-687.
    • (2005) Magn. Reson. Chem. , vol.43 , pp. 681-687
    • Exarchou, V.1    Krucker, M.2    van Beek, T.A.3    Vervoort, J.4
  • 46
    • 33645812730 scopus 로고    scopus 로고
    • Hyphenated chromatographic techniques for the rapid screening and identification of antioxidants in methanolic extracts of pharmaceutically used plants
    • Exarchou, V., Fiamegos, Y. C., van Beek, T. A., Nanos, C., et al., Hyphenated chromatographic techniques for the rapid screening and identification of antioxidants in methanolic extracts of pharmaceutically used plants, J. Chromatogr. A 2006, 1112, 293-302.
    • (2006) J. Chromatogr. A , vol.1112 , pp. 293-302
    • Exarchou, V.1    Fiamegos, Y.C.2    van Beek, T.A.3    Nanos, C.4
  • 47
    • 33846207483 scopus 로고    scopus 로고
    • Identification of the major constituents of Hypericum perfo-ratum by LC/SPE/NMR and/or LC/MS
    • Tatsis, E. C., Boeren, S., Exarchou, V., Troganis, A. N., et al., Identification of the major constituents of Hypericum perfo-ratum by LC/SPE/NMR and/or LC/MS, Phytochemistry 2007, 68, 383-393.
    • (2007) Phytochemistry , vol.68 , pp. 383-393
    • Tatsis, E.C.1    Boeren, S.2    Exarchou, V.3    Troganis, A.N.4
  • 48
    • 0037048454 scopus 로고    scopus 로고
    • 13C GE-HSQC and GE-HMBC NMR studies of flavonols and flavones in organic and aqueous mixtures
    • 13C GE-HSQC and GE-HMBC NMR studies of flavonols and flavones in organic and aqueous mixtures, Tetrahedron 2002, 58, 7423-7429.
    • (2002) Tetrahedron , vol.58 , pp. 7423-7429
    • Exarchou, V.1    Troganis, A.2    Gerothanassis, I.P.3    Tsimidou, M.4
  • 49
    • 21644485321 scopus 로고    scopus 로고
    • Separation and identification of phenolic compounds in olive oil by coupling high-performance liquid chromatography with postcolumn solid-phase extraction to nuclear magnetic resonance spectroscopy (LC-SPE-NMR)
    • Christophoridou, S., Dais, P., Tseng, L. I.-H., Spraul, M., Separation and identification of phenolic compounds in olive oil by coupling high-performance liquid chromatography with postcolumn solid-phase extraction to nuclear magnetic resonance spectroscopy (LC-SPE-NMR), J. Agric. Food Chem. 2005, 53, 4667-4679.
    • (2005) J. Agric. Food Chem. , vol.53 , pp. 4667-4679
    • Christophoridou, S.1    Dais, P.2    Tseng, L.I.-H.3    Spraul, M.4
  • 50
    • 34249868772 scopus 로고    scopus 로고
    • Effects of enrichment of refined olive oil with phenolic compounds from olive leaves
    • Paiva-Martins, F., Correia, R., Felix, S., Ferreira, P., et al., Effects of enrichment of refined olive oil with phenolic compounds from olive leaves, J. Agric. Food Chem. 2007, 55, 4139-4143.
    • (2007) J. Agric. Food Chem. , vol.55 , pp. 4139-4143
    • Paiva-Martins, F.1    Correia, R.2    Felix, S.3    Ferreira, P.4
  • 51
    • 0034843004 scopus 로고    scopus 로고
    • Antioxidant activity of hydroxytyrosol acetate compared with that of other olive oil polyphenols
    • Gordon, M. H., Paiva-Martins, F., Almeida, M., Antioxidant activity of hydroxytyrosol acetate compared with that of other olive oil polyphenols, J. Agric. Food Chem. 2001, 49, 2480-2485.
    • (2001) J. Agric. Food Chem. , vol.49 , pp. 2480-2485
    • Gordon, M.H.1    Paiva-Martins, F.2    Almeida, M.3
  • 52
    • 0030741461 scopus 로고    scopus 로고
    • Flavonoids, dietary-derived inhibitors of cell proliferation and in vitro angiogenesis
    • Fotsis, T., Pepper, M. S., Aktas, E., Breit, S., et al., Flavonoids, dietary-derived inhibitors of cell proliferation and in vitro angiogenesis, Cancer Res. 1997, 57, 2916-2921.
    • (1997) Cancer Res. , vol.57 , pp. 2916-2921
    • Fotsis, T.1    Pepper, M.S.2    Aktas, E.3    Breit, S.4
  • 53
    • 0037407899 scopus 로고    scopus 로고
    • In vitro cytotoxicity to human cells in culture of some phenolics from olive oil
    • Babich, H., Visioli, F., In vitro cytotoxicity to human cells in culture of some phenolics from olive oil, Farmaco 2003, 58, 403-407.
    • (2003) Farmaco , vol.58 , pp. 403-407
    • Babich, H.1    Visioli, F.2
  • 54
    • 0036684228 scopus 로고    scopus 로고
    • Cancer chemoprevention by hydroxytyrosol isolated from virgin olive oil through G1 cell cycle arrest and apoptosis
    • Fabiani, R., De Bartolomeo, A., Rosignoli, P., Servili, M., et al., Cancer chemoprevention by hydroxytyrosol isolated from virgin olive oil through G1 cell cycle arrest and apoptosis, Eur. J. Cancer Prev. 2002, 11, 351-358
    • (2002) Eur. J. Cancer Prev. , vol.11 , pp. 351-358
    • Fabiani, R.1    De Bartolomeo, A.2    Rosignoli, P.3    Servili, M.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.