Cephalostatin 1 Selectively Triggers the Release of Smac/DIABLO and Subsequent Apoptosis That Is Characterized by an Increased Density of the Mitochondrial Matrix

Cancer Research

Volumn 63, Issue 24, 2003, Pages 8869-8876

  Dirsch, Verena M ^a,d   Müller, Irina M ^a   Eichhorst, Sören T ^b   Pettit, George R ^c   Kamano, Yoshiaki ^c   Inoue, Masuo ^c   Xu, Jun Ping ^c   Ichihara, Yoshitatsu ^c   Wanner, Gerhard ^a   Vollmar, Angelika M ^a  

^a UNIVERSITY OF MUNICH   (Germany)

^b LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^c ARIZONA STATE UNIVERSITY   (United States)

^d Center of Drug Research   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS INDUCING FACTOR; APOPTOSIS INHIBITOR; APOPTOTIC PROTEASE ACTIVATING FACTOR 1; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; BINDING PROTEIN; CARRIER PROTEIN; CASPASE; CASPASE 8; CASPASE 9; CASPASE INHIBITOR; CD95 DEATH RECEPTOR; CEPHALOSTATIN 1; CEPHALOSTATIN I; CYTOCHROME C; DIABLO PROTEIN, HUMAN; DNA FRAGMENT; ETOPOSIDE; FAS ANTIGEN; IAP LIKE PROTEIN, VERTEBRATE; IAP-LIKE PROTEIN, VERTEBRATE; MITOCHONDRIAL PROTEIN; NANOPARTICLE; NATURAL PRODUCT; PHENAZINE DERIVATIVE; PROTEIN; PROTEIN BCL 2; PROTEIN BCL X; SECOND MITOCHONDRIAL ACTIVATOR OF CASPASE; SPIRO COMPOUND; STAUROSPORINE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; BIOSYNTHESIS; CELL MEMBRANE PERMEABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; DOSE TIME EFFECT RELATION; DRUG CYTOTOXICITY; DRUG EFFECT; DRUG MECHANISM; ENZYME ACTIVATION; ENZYMOLOGY; HUMAN; HUMAN CELL; IN VITRO STUDY; INTRACELLULAR MEMBRANE; ISOELECTRIC POINT; LEUKEMIA CELL; LEUKEMIA CELL LINE; MEMBRANE POTENTIAL; METABOLISM; MITOCHONDRIAL MEMBRANE; MITOCHONDRION; PATHOLOGY; PHYSIOLOGY; PRIORITY JOURNAL; PROTEIN SECRETION; SIGNAL TRANSDUCTION; T CELL LEUKEMIA; TRANSMISSION ELECTRON MICROSCOPY; WESTERN BLOTTING;

APOPTOSIS; APOPTOTIC PROTEASE-ACTIVATING FACTOR 1; BCL-X PROTEIN; CARRIER PROTEINS; CASPASE 8; CASPASE 9; CASPASES; CELL MEMBRANE PERMEABILITY; HUMANS; INTRACELLULAR MEMBRANES; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; JURKAT CELLS; LEUKEMIA, T-CELL; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; PHENAZINES; PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; SPIRO COMPOUNDS; STEROIDS; X-LINKED INHIBITOR OF APOPTOSIS PROTEIN;

EID: 9144226235     PISSN: 00085472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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