Processing of the Nedd2 precursor by ICE-like proteases and granzyme B

Genes to Cells

Volumn 1, Issue 7, 1996, Pages 673-685

  Harvey, Natasha L ^a   Trapani, Joseph A ^b   Fernandes Alnemri, Teresa ^c   Litwack, Gerald ^c   Alnemri, Emad S ^c   Kumar, Sharad ^a  

^a INSTITUTE OF MEDICAL AND VETERINARY SCIENCE   (Australia)

^b AUSTIN RESEARCH INSTITUTE   (Australia)

^c THOMAS JEFFERSON UNIVERSITY HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CASP2 PROTEIN, HUMAN; CASP2 PROTEIN, MOUSE; CASPASE 2; CYSTEINE PROTEINASE; ENZYME PRECURSOR; GRANZYME; GZMB PROTEIN, HUMAN; GZMB PROTEIN, MOUSE; INTERLEUKIN 1BETA CONVERTING ENZYME; PRIMER DNA; PROTEINASE INHIBITOR; RECOMBINANT PROTEIN; SERINE PROTEINASE;

ANIMAL; APOPTOSIS; ARTICLE; CAENORHABDITIS ELEGANS; CELL STRAIN 3T3; CHEMISTRY; CYTOTOXIC T LYMPHOCYTE; GENETICS; HUMAN; IN VITRO STUDY; METABOLISM; MOUSE; NUCLEOTIDE SEQUENCE; PROTEIN CONFORMATION; PROTEIN PROCESSING;

3T3 CELLS; ANIMALS; APOPTOSIS; BASE SEQUENCE; CAENORHABDITIS ELEGANS; CASPASE 1; CASPASE 2; CYSTEINE ENDOPEPTIDASES; DNA PRIMERS; ENZYME PRECURSORS; GRANZYMES; HUMANS; MICE; PROTEASE INHIBITORS; PROTEIN CONFORMATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RECOMBINANT PROTEINS; SERINE ENDOPEPTIDASES; T-LYMPHOCYTES, CYTOTOXIC;

EID: 0030179872     PISSN: 13569597     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2443.1996.00255.x     Document Type: Article

References (5)

1. Casciola-Rosen, L.A., Anhalt, G.J. & Rosen, A. (1995) DNA-dependent protein kinase is one of a subset of autoantigens specifically cleaved early during apoptosis. J. Exp. Med. 182, 1625-1634.
2. Casciola-Rosen, L., Nicholson, D.W., Chong, K.R., et al. (1996) Apopain/CPP32 cleaves proteins that arc essential for cellular repair: a fundamental principle of apoptotic death. J. Exp. Med., in press.
3. Chinnaiyan, A.M., Orth, K., O'Rourkc, K., Duan, H., Poirier, G.G. & Dixit, V.M. (1996) Molecular ordering of the cell death pathway: Bcl-2 and Bc1-XL function upstream of the CED-3-like apoptotic proteases. J. Biol. Chem. 271, 4573-4576.
4. Darmon, A.J., Ehrman, N., Caputo, A., Fujinaga, J. & Blcackley, R.C. (1994) The cytotoxic T cell protcasc granzyme D docs not activate interlcukin-1β-converting enzyme. J. Biol. Chem. 269, 32043-32046.
5. Darmon, A.J., Nicholson, D.W. & Bleackley, R.C. (1995) Activation of the apoptotic protcasc CPP32 by cytotoxic T-cell-derivcd granzyme, B. Nature 377, 446-148.